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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: Methyl ethyl ketoxime
CASRN: ="96-29-7"
Study Number: C88009
Exposure Route: DOSED WATER
TDMS Number: 8800904
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Centrilobular 10000 PPM 10 59 59 92 1 Cytomegaly Mild Terminal Sacrifice
Alimentary System Liver Centrilobular 10000 PPM 10 51 51 92 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Alimentary System Liver Centrilobular 10000 PPM 10 52 52 92 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Alimentary System Liver Centrilobular 10000 PPM 10 53 53 92 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Alimentary System Liver Centrilobular 10000 PPM 10 54 54 92 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Alimentary System Liver Centrilobular 10000 PPM 10 55 55 92 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Alimentary System Liver Centrilobular 10000 PPM 10 56 56 92 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Alimentary System Liver Centrilobular 10000 PPM 10 58 58 92 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Alimentary System Liver Centrilobular 10000 PPM 10 60 60 92 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Alimentary System Liver Kupffer Cell 10000 PPM 10 52 52 92 1 Erythrophagocytosis Minimal Terminal Sacrifice
Alimentary System Liver Kupffer Cell 10000 PPM 10 53 53 92 1 Erythrophagocytosis Minimal Terminal Sacrifice
Alimentary System Liver Kupffer Cell 10000 PPM 10 54 54 92 1 Erythrophagocytosis Mild Terminal Sacrifice
Alimentary System Liver Kupffer Cell 10000 PPM 10 55 55 92 1 Erythrophagocytosis Minimal Terminal Sacrifice
Alimentary System Liver Kupffer Cell 10000 PPM 10 56 56 92 1 Erythrophagocytosis Minimal Terminal Sacrifice
Alimentary System Liver Kupffer Cell 10000 PPM 10 57 57 92 1 Erythrophagocytosis Minimal Terminal Sacrifice
Alimentary System Liver Kupffer Cell 10000 PPM 10 58 58 92 1 Erythrophagocytosis Minimal Terminal Sacrifice
Alimentary System Liver Kupffer Cell 10000 PPM 10 60 60 92 1 Erythrophagocytosis Minimal Terminal Sacrifice
Alimentary System Liver Kupffer Cell 10000 PPM 10 51 51 92 1 Pigmentation Mild Terminal Sacrifice
Alimentary System Liver Kupffer Cell 10000 PPM 10 52 52 92 1 Pigmentation Mild Terminal Sacrifice
Alimentary System Liver Kupffer Cell 10000 PPM 10 53 53 92 1 Pigmentation Mild Terminal Sacrifice
Alimentary System Liver Kupffer Cell 10000 PPM 10 54 54 92 1 Pigmentation Mild Terminal Sacrifice
Alimentary System Liver Kupffer Cell 10000 PPM 10 55 55 92 1 Pigmentation Mild Terminal Sacrifice
Alimentary System Liver Kupffer Cell 10000 PPM 10 56 56 92 1 Pigmentation Mild Terminal Sacrifice
Alimentary System Liver Kupffer Cell 10000 PPM 10 57 57 92 1 Pigmentation Mild Terminal Sacrifice
Alimentary System Liver Kupffer Cell 10000 PPM 10 58 58 92 1 Pigmentation Mild Terminal Sacrifice
Alimentary System Liver Kupffer Cell 10000 PPM 10 59 59 92 1 Pigmentation Mild Terminal Sacrifice
Alimentary System Liver Kupffer Cell 10000 PPM 10 60 60 92 1 Pigmentation Mild Terminal Sacrifice
Alimentary System Pancreas Acinar Cell 5000 PPM 1 48 48 92 1 Hypoplasia Marked Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 9 9 92 1 Inflammation Minimal, Focal, Acute Terminal Sacrifice
Endocrine System Adrenal Cortex Subcapsular 10000 PPM 10 52 52 92 1 Hyperplasia Minimal Terminal Sacrifice
Genital System Preputial Gland 625 PPM 1 16 16 92 1 Inflammation Moderate Terminal Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 51 51 92 1 Pigmentation Minimal Terminal Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 52 52 92 1 Pigmentation Minimal Terminal Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 53 53 92 1 Pigmentation Minimal Terminal Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 54 54 92 1 Pigmentation Minimal Terminal Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 55 55 92 1 Pigmentation Minimal Terminal Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 56 56 92 1 Pigmentation Minimal Terminal Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 57 57 92 1 Pigmentation Minimal Terminal Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 58 58 92 1 Pigmentation Minimal Terminal Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 59 59 92 1 Pigmentation Minimal Terminal Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 60 60 92 1 Pigmentation Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 10 2 2 92 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 41 41 92 1 Hyperplasia Mild, Erythrocyte Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 42 42 92 1 Hyperplasia Minimal, Erythrocyte Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 43 43 92 1 Hyperplasia Mild, Erythrocyte Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 44 44 92 1 Hyperplasia Mild, Erythrocyte Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 45 45 92 1 Hyperplasia Minimal, Erythrocyte Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 46 46 92 1 Hyperplasia Minimal, Erythrocyte Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 47 47 92 1 Hyperplasia Minimal, Erythrocyte Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 48 48 92 1 Hyperplasia Mild, Erythrocyte Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 49 49 92 1 Hyperplasia Mild, Erythrocyte Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 50 50 92 1 Hyperplasia Minimal, Erythrocyte Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 51 51 92 1 Hyperplasia Moderate, Erythrocyte Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 52 52 92 1 Hyperplasia Moderate, Erythrocyte Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 53 53 92 1 Hyperplasia Moderate, Erythrocyte Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 54 54 92 1 Hyperplasia Moderate, Erythrocyte Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 55 55 92 1 Hyperplasia Mild, Erythrocyte Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 56 56 92 1 Hyperplasia Moderate, Erythrocyte Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 57 57 92 1 Hyperplasia Moderate, Erythrocyte Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 58 58 92 1 Hyperplasia Moderate, Erythrocyte Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 59 59 92 1 Hyperplasia Moderate, Erythrocyte Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 60 60 92 1 Hyperplasia Mild, Erythrocyte Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 41 41 92 1 Pigmentation Mild Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 42 42 92 1 Pigmentation Minimal Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 44 44 92 1 Pigmentation Mild Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 51 51 92 1 Pigmentation Mild Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 52 52 92 1 Pigmentation Mild Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 53 53 92 1 Pigmentation Mild Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 54 54 92 1 Pigmentation Mild Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 55 55 92 1 Pigmentation Mild Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 56 56 92 1 Pigmentation Mild Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 57 57 92 1 Pigmentation Mild Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 58 58 92 1 Pigmentation Mild Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 59 59 92 1 Pigmentation Mild Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 60 60 92 1 Pigmentation Mild Terminal Sacrifice
Hematopoietic System Thymus Vehicle Control 10 10 10 92 1 Hemorrhage Minimal Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 2 2 92 1 Hemorrhage Minimal Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 3 3 92 1 Hemorrhage Minimal Terminal Sacrifice
Respiratory System Lung 625 PPM 1 15 15 92 1 Hemorrhage Minimal Terminal Sacrifice
Respiratory System Lung 1250 PPM 1 28 28 92 1 Hemorrhage Minimal Terminal Sacrifice
Respiratory System Lung 5000 PPM 1 44 44 92 1 Hemorrhage Mild Terminal Sacrifice
Respiratory System Lung 10000 PPM 10 57 57 92 1 Hemorrhage Mild Terminal Sacrifice
Respiratory System Lung 625 PPM 1 15 15 92 1 Inflammation Mild, Focal, Chronic Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 41 41 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 42 42 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 43 43 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 44 44 92 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 45 45 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 47 47 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 49 49 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10000 PPM 10 51 51 92 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10000 PPM 10 52 52 92 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10000 PPM 10 53 53 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10000 PPM 10 54 54 92 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10000 PPM 10 55 55 92 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10000 PPM 10 56 56 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10000 PPM 10 57 57 92 1 Degeneration Moderate Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10000 PPM 10 58 58 92 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10000 PPM 10 59 59 92 1 Degeneration Moderate Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10000 PPM 10 60 60 92 1 Degeneration Mild Terminal Sacrifice
Urinary System Kidney Renal Tubule 10000 PPM 10 52 52 92 1 Pigmentation Minimal Terminal Sacrifice
Urinary System Kidney Renal Tubule 10000 PPM 10 53 53 92 1 Pigmentation Minimal Terminal Sacrifice
Urinary System Kidney Renal Tubule 10000 PPM 10 56 56 92 1 Pigmentation Minimal Terminal Sacrifice
Urinary System Kidney Renal Tubule 10000 PPM 10 58 58 92 1 Pigmentation Minimal Terminal Sacrifice
Urinary System Kidney Renal Tubule 10000 PPM 10 60 60 92 1 Pigmentation Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 2 2 92 1 Infiltration Cellular Mild, Focal, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 1250 PPM 10 22 22 92 1 Hyperplasia Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 1250 PPM 10 23 23 92 1 Hyperplasia Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 1250 PPM 10 24 24 92 1 Hyperplasia Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 1250 PPM 10 25 25 92 1 Hyperplasia Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 1250 PPM 10 27 27 92 1 Hyperplasia Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 2500 PPM 10 32 32 92 1 Hyperplasia Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 2500 PPM 10 34 34 92 1 Hyperplasia Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 2500 PPM 10 35 35 92 1 Hyperplasia Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 2500 PPM 10 36 36 92 1 Hyperplasia Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 2500 PPM 10 37 37 92 1 Hyperplasia Mild Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 2500 PPM 10 38 38 92 1 Hyperplasia Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 2500 PPM 10 39 39 92 1 Hyperplasia Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 2500 PPM 10 40 40 92 1 Hyperplasia Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 5000 PPM 10 41 41 92 1 Hyperplasia Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 5000 PPM 10 43 43 92 1 Hyperplasia Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 5000 PPM 10 44 44 92 1 Hyperplasia Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 5000 PPM 10 45 45 92 1 Hyperplasia Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 5000 PPM 10 47 47 92 1 Hyperplasia Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 5000 PPM 10 48 48 92 1 Hyperplasia Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 5000 PPM 10 49 49 92 1 Hyperplasia Mild Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 5000 PPM 10 50 50 92 1 Hyperplasia Mild Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 10000 PPM 10 51 51 92 1 Hyperplasia Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 10000 PPM 10 52 52 92 1 Hyperplasia Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 10000 PPM 10 53 53 92 1 Hyperplasia Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 10000 PPM 10 54 54 92 1 Hyperplasia Mild Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 10000 PPM 10 55 55 92 1 Hyperplasia Mild Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 10000 PPM 10 56 56 92 1 Hyperplasia Mild Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 10000 PPM 10 57 57 92 1 Hyperplasia Mild Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 10000 PPM 10 58 58 92 1 Hyperplasia Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 10000 PPM 10 59 59 92 1 Hyperplasia Mild Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 10000 PPM 10 60 60 92 1 Hyperplasia Mild Terminal Sacrifice
Urinary System Urinary Bladder Vehicle Control 10 3 3 92 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 1250 PPM 10 23 23 92 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 1250 PPM 10 24 24 92 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 2500 PPM 10 32 32 92 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 2500 PPM 10 33 33 92 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 2500 PPM 10 34 34 92 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 2500 PPM 10 38 38 92 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 2500 PPM 10 39 39 92 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 2500 PPM 10 40 40 92 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 5000 PPM 10 43 43 92 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 5000 PPM 10 44 44 92 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 5000 PPM 10 47 47 92 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 5000 PPM 10 48 48 92 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 5000 PPM 10 49 49 92 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 10000 PPM 10 52 52 92 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 10000 PPM 10 53 53 92 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 10000 PPM 10 54 54 92 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 10000 PPM 10 55 55 92 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 10000 PPM 10 56 56 92 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 10000 PPM 10 57 57 92 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 10000 PPM 10 58 58 92 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 10000 PPM 10 59 59 92 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 10000 PPM 10 60 60 92 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 2500 PPM 10 31 31 92 1 Pigmentation Mild Terminal Sacrifice
Urinary System Urinary Bladder 2500 PPM 10 39 39 92 1 Pigmentation Mild Terminal Sacrifice
Urinary System Urinary Bladder 10000 PPM 10 52 52 92 1 Pigmentation Mild Terminal Sacrifice