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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: Urethane + ethanol (combination)
CASRN: ="URETHCOMB"
Study Number: C00602C
Exposure Route:
TDMS Number: 0060203
Sex: Female
Strain and Species: F 344/N Rats

Female Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Untreated Control 10 67 331 93 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver Untreated Control 10 67 332 93 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver Untreated Control 10 68 338 93 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver Untreated Control 10 68 340 93 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 110 PPM 9 69 342 93 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 110 PPM 9 70 348 93 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 330 PPM 8 71 351 93 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 10000 PPM 10 77 384 16 1 Hepatodiaphragmatic Nodule Moribund Sacrifice
Alimentary System Mesentery 3300 PPM 1 75 374 93 1 Foreign Body Mild Terminal Sacrifice
Alimentary System Mesentery 3300 PPM 1 75 374 93 1 Granuloma Moderate Terminal Sacrifice
Alimentary System Pancreas Untreated Control 10 68 338 93 1 Inflammation Minimal, Chronic Terminal Sacrifice
Alimentary System Stomach Forestomach 10000 PPM 10 78 387 29 1 Hyperplasia Mild, Squamous Moribund Sacrifice
Alimentary System Stomach Glandular Untreated Control 10 67 335 93 1 Granuloma Minimal Terminal Sacrifice
Cardiovascular System Heart Untreated Control 10 67 333 93 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Untreated Control 10 67 334 93 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Untreated Control 10 67 335 93 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Untreated Control 10 68 337 93 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Untreated Control 10 68 339 93 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart 3300 PPM 10 75 371 93 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart 3300 PPM 10 75 373 93 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart 3300 PPM 10 75 374 93 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart 3300 PPM 10 76 376 93 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart 3300 PPM 10 76 379 93 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart 3300 PPM 10 76 380 93 1 Cardiomyopathy Minimal Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 3300 PPM 10 75 372 93 1 Cyst Terminal Sacrifice
Endocrine System Thyroid Gland 10000 PPM 10 77 381 36 1 Ultimobranchial Cyst Minimal Moribund Sacrifice
Genital System Clitoral Gland 1100 PPM 1 73 365 93 1 Cyst Terminal Sacrifice
Genital System Ovary 110 PPM 1 70 348 93 1 Cyst Terminal Sacrifice
Genital System Ovary 330 PPM 2 71 353 93 1 Cyst Terminal Sacrifice
Genital System Ovary 1100 PPM 2 73 363 93 1 Cyst Terminal Sacrifice
Genital System Ovary 1100 PPM 2 74 369 93 1 Cyst Terminal Sacrifice
Genital System Ovary 3300 PPM 10 75 375 93 1 Cyst Terminal Sacrifice
Genital System Ovary 330 PPM 2 71 352 93 1 Ovotestis Terminal Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 77 381 36 1 Depletion Cellular Mild Moribund Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 77 382 36 1 Depletion Cellular Mild Moribund Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 77 383 16 1 Depletion Cellular Moderate Moribund Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 77 384 16 1 Depletion Cellular Moderate Moribund Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 77 385 35 1 Depletion Cellular Moderate Moribund Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 78 386 16 1 Depletion Cellular Moderate Moribund Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 78 387 29 1 Depletion Cellular Moderate Moribund Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 78 388 16 1 Depletion Cellular Moderate Moribund Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 78 389 16 1 Depletion Cellular Moderate Moribund Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 78 390 36 1 Depletion Cellular Mild Moribund Sacrifice
Hematopoietic System Lymph Node Mandibular 3300 PPM 10 75 372 93 1 Depletion Lymphoid Mild Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 3300 PPM 10 75 374 93 1 Depletion Lymphoid Moderate Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 3300 PPM 10 76 376 93 1 Depletion Lymphoid Mild Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 10000 PPM 10 77 381 36 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Lymph Node Mandibular 10000 PPM 10 77 382 36 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Lymph Node Mandibular 10000 PPM 10 77 383 16 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Lymph Node Mandibular 10000 PPM 10 77 384 16 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Lymph Node Mandibular 10000 PPM 10 77 385 35 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Lymph Node Mandibular 10000 PPM 10 78 386 16 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Lymph Node Mandibular 10000 PPM 10 78 387 29 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Lymph Node Mandibular 10000 PPM 10 78 388 16 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Lymph Node Mandibular 10000 PPM 10 78 389 16 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Lymph Node Mandibular 10000 PPM 10 78 390 36 1 Depletion Lymphoid Minimal Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 3300 PPM 10 75 372 93 1 Depletion Lymphoid Mild Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 3300 PPM 10 75 374 93 1 Depletion Lymphoid Mild Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 10000 PPM 10 77 381 36 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 10000 PPM 10 77 382 36 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 10000 PPM 10 77 383 16 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 10000 PPM 10 77 384 16 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 10000 PPM 10 77 385 35 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 10000 PPM 10 78 386 16 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 10000 PPM 10 78 387 29 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 10000 PPM 10 78 388 16 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 10000 PPM 10 78 389 16 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 10000 PPM 10 78 390 36 1 Depletion Lymphoid Mild Moribund Sacrifice
Hematopoietic System Lymph Node Pancreatic 3300 PPM 10 75 374 93 1 Hyperplasia Moderate, Lymphoid Terminal Sacrifice
Hematopoietic System Spleen 3300 PPM 10 75 371 93 1 Depletion Lymphoid Minimal Terminal Sacrifice
Hematopoietic System Spleen 3300 PPM 10 75 372 93 1 Depletion Lymphoid Minimal Terminal Sacrifice
Hematopoietic System Spleen 3300 PPM 10 75 373 93 1 Depletion Lymphoid Mild Terminal Sacrifice
Hematopoietic System Spleen 3300 PPM 10 75 374 93 1 Depletion Lymphoid Mild Terminal Sacrifice
Hematopoietic System Spleen 3300 PPM 10 75 375 93 1 Depletion Lymphoid Mild Terminal Sacrifice
Hematopoietic System Spleen 3300 PPM 10 76 376 93 1 Depletion Lymphoid Mild Terminal Sacrifice
Hematopoietic System Spleen 3300 PPM 10 76 377 93 1 Depletion Lymphoid Mild Terminal Sacrifice
Hematopoietic System Spleen 3300 PPM 10 76 378 93 1 Depletion Lymphoid Minimal Terminal Sacrifice
Hematopoietic System Spleen 3300 PPM 10 76 380 93 1 Depletion Lymphoid Minimal Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 77 381 36 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Spleen 10000 PPM 10 77 382 36 1 Depletion Lymphoid Mild Moribund Sacrifice
Hematopoietic System Spleen 10000 PPM 10 77 383 16 1 Depletion Lymphoid Minimal Moribund Sacrifice
Hematopoietic System Spleen 10000 PPM 10 77 384 16 1 Depletion Lymphoid Mild Moribund Sacrifice
Hematopoietic System Spleen 10000 PPM 10 77 385 35 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Spleen 10000 PPM 10 78 386 16 1 Depletion Lymphoid Minimal Moribund Sacrifice
Hematopoietic System Spleen 10000 PPM 10 78 387 29 1 Depletion Lymphoid Mild Moribund Sacrifice
Hematopoietic System Spleen 10000 PPM 10 78 388 16 1 Depletion Lymphoid Mild Moribund Sacrifice
Hematopoietic System Spleen 10000 PPM 10 78 389 16 1 Depletion Lymphoid Mild Moribund Sacrifice
Hematopoietic System Spleen 10000 PPM 10 78 390 36 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Thymus 10000 PPM 10 78 387 29 1 Depletion Lymphoid Moderate Moribund Sacrifice
Respiratory System Lung 1100 PPM 2 73 362 93 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung 1100 PPM 2 73 365 93 1 Inflammation Mild, Chronic Terminal Sacrifice
Respiratory System Nose Glands Untreated Control 10 68 339 93 1 Inflammation Minimal, Acute Terminal Sacrifice
Special Senses System Eye 110 PPM 1 70 348 93 1 Inflammation Marked, Chronic Active Terminal Sacrifice
Urinary System Kidney Cortex Untreated Control 10 67 331 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex Untreated Control 10 67 332 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex Untreated Control 10 67 333 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex Untreated Control 10 67 334 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex Untreated Control 10 67 335 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex Untreated Control 10 68 337 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex Untreated Control 10 68 338 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex Untreated Control 10 68 339 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex Untreated Control 10 68 340 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 110 PPM 10 69 341 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 110 PPM 10 69 342 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 110 PPM 10 69 343 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 110 PPM 10 69 344 93 1 Mineralization Mild Terminal Sacrifice
Urinary System Kidney Cortex 110 PPM 10 70 346 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 110 PPM 10 70 347 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 110 PPM 10 70 348 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 110 PPM 10 70 349 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 110 PPM 10 70 350 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 330 PPM 10 71 351 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 330 PPM 10 71 352 93 1 Mineralization Mild Terminal Sacrifice
Urinary System Kidney Cortex 330 PPM 10 71 353 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 330 PPM 10 71 355 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 330 PPM 10 72 356 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 330 PPM 10 72 358 93 1 Mineralization Mild Terminal Sacrifice
Urinary System Kidney Cortex 330 PPM 10 72 360 93 1 Mineralization Mild Terminal Sacrifice
Urinary System Kidney Cortex 1100 PPM 10 73 361 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 1100 PPM 10 73 362 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 1100 PPM 10 73 363 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 1100 PPM 10 73 364 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 1100 PPM 10 73 365 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 1100 PPM 10 74 366 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 1100 PPM 10 74 367 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 1100 PPM 10 74 368 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 1100 PPM 10 74 369 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 1100 PPM 10 74 370 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 3300 PPM 10 75 371 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 3300 PPM 10 75 372 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 3300 PPM 10 75 373 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 3300 PPM 10 75 374 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 3300 PPM 10 75 375 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 3300 PPM 10 76 376 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 3300 PPM 10 76 377 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 3300 PPM 10 76 378 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 3300 PPM 10 76 379 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 3300 PPM 10 76 380 93 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Cortex 10000 PPM 10 77 381 36 1 Mineralization Minimal Moribund Sacrifice
Urinary System Kidney Cortex 10000 PPM 10 77 383 16 1 Mineralization Minimal Moribund Sacrifice
Urinary System Kidney Cortex 10000 PPM 10 77 384 16 1 Mineralization Minimal Moribund Sacrifice
Urinary System Kidney Cortex 10000 PPM 10 77 385 35 1 Mineralization Minimal Moribund Sacrifice
Urinary System Kidney Cortex 10000 PPM 10 78 386 16 1 Mineralization Minimal Moribund Sacrifice
Urinary System Kidney Cortex 10000 PPM 10 78 388 16 1 Mineralization Minimal Moribund Sacrifice
Urinary System Kidney Cortex 10000 PPM 10 78 389 16 1 Mineralization Minimal Moribund Sacrifice
Urinary System Kidney Cortex 10000 PPM 10 78 390 36 1 Mineralization Minimal Moribund Sacrifice
Urinary System Kidney Untreated Control 10 67 332 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Untreated Control 10 67 333 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Untreated Control 10 68 336 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Untreated Control 10 68 339 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 110 PPM 10 69 342 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 110 PPM 10 69 343 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 110 PPM 10 70 347 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 110 PPM 10 70 348 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 110 PPM 10 70 349 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 110 PPM 10 70 350 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 330 PPM 10 71 354 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 330 PPM 10 71 355 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 330 PPM 10 72 358 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1100 PPM 10 73 363 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1100 PPM 10 73 365 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1100 PPM 10 74 366 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1100 PPM 10 74 369 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1100 PPM 10 74 370 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3300 PPM 10 75 371 93 1 Nephropathy Mild Terminal Sacrifice
Urinary System Kidney 3300 PPM 10 75 372 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3300 PPM 10 75 373 93 1 Nephropathy Moderate Terminal Sacrifice
Urinary System Kidney 3300 PPM 10 75 374 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3300 PPM 10 75 375 93 1 Nephropathy Mild Terminal Sacrifice
Urinary System Kidney 3300 PPM 10 76 376 93 1 Nephropathy Mild Terminal Sacrifice
Urinary System Kidney 3300 PPM 10 76 377 93 1 Nephropathy Moderate Terminal Sacrifice
Urinary System Kidney 3300 PPM 10 76 378 93 1 Nephropathy Mild Terminal Sacrifice
Urinary System Kidney 3300 PPM 10 76 379 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3300 PPM 10 76 380 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 10000 PPM 10 77 382 36 1 Nephropathy Minimal Moribund Sacrifice
Urinary System Kidney 10000 PPM 10 77 384 16 1 Nephropathy Minimal Moribund Sacrifice
Urinary System Kidney 10000 PPM 10 78 386 16 1 Nephropathy Minimal Moribund Sacrifice
Urinary System Kidney 10000 PPM 10 78 388 16 1 Nephropathy Minimal Moribund Sacrifice
Urinary System Kidney 10000 PPM 10 78 389 16 1 Nephropathy Minimal Moribund Sacrifice