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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: Urethane + ethanol (combination)
CASRN: ="URETHCOMB"
Study Number: C00602C
Exposure Route:
TDMS Number: 0060204
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Untreated Control 10 125 125 93 1 Fatty Change Minimal Terminal Sacrifice
Alimentary System Liver Untreated Control 10 129 129 93 1 Fatty Change Mild Terminal Sacrifice
Alimentary System Pancreas 10000 PPM 10 171 171 17 1 Inflammation Mild, Chronic Moribund Sacrifice
Alimentary System Stomach Forestomach Untreated Control 10 127 127 93 1 Inflammation Minimal, Chronic Terminal Sacrifice
Alimentary System Stomach Glandular 10000 PPM 10 171 171 17 1 Mineralization Minimal Moribund Sacrifice
Alimentary System Stomach Glandular 10000 PPM 10 176 176 17 1 Mineralization Mild Moribund Sacrifice
Alimentary System Stomach Glandular 10000 PPM 10 179 179 17 1 Mineralization Mild Moribund Sacrifice
Alimentary System Stomach Glandular 10000 PPM 10 180 180 17 1 Mineralization Mild Moribund Sacrifice
Cardiovascular System Heart 1100 PPM 10 156 156 93 1 Hemorrhage Mild Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule Untreated Control 10 121 121 93 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule Untreated Control 10 123 123 93 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule Untreated Control 10 129 129 93 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule Untreated Control 10 130 130 93 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule 330 PPM 1 141 141 84 1 Hyperplasia Minimal Accidentally Killed
Endocrine System Adrenal Cortex Capsule 3300 PPM 10 165 165 93 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule 10000 PPM 10 180 180 17 1 Hyperplasia Minimal Moribund Sacrifice
Endocrine System Adrenal Medulla Untreated Control 10 126 126 93 1 Hyperplasia Mild Terminal Sacrifice
Endocrine System Parathyroid Gland Untreated Control 10 121 121 93 1 Cyst Terminal Sacrifice
Endocrine System Parathyroid Gland 3300 PPM 10 163 163 93 1 Cyst Terminal Sacrifice
Endocrine System Thyroid Gland Untreated Control 10 126 126 93 1 Inflammation Minimal, Chronic Terminal Sacrifice
Genital System Prostate 3300 PPM 10 165 165 93 1 Concretion Mild Terminal Sacrifice
Genital System Prostate 3300 PPM 10 169 169 93 1 Concretion Mild Terminal Sacrifice
Genital System Prostate 3300 PPM 10 170 170 93 1 Concretion Mild Terminal Sacrifice
Genital System Testes 10000 PPM 10 175 175 17 1 Cyst Moribund Sacrifice
Hematopoietic System Bone Marrow 3300 PPM 10 162 162 93 1 Depletion Cellular Mild Terminal Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 171 171 17 1 Depletion Cellular Mild Moribund Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 172 172 17 1 Depletion Cellular Mild Moribund Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 173 173 17 1 Depletion Cellular Mild Moribund Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 177 177 17 1 Depletion Cellular Mild Moribund Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 180 180 17 1 Depletion Cellular Mild Moribund Sacrifice
Hematopoietic System Lymph Node Inguinal Untreated Control 10 127 127 93 1 Hyperplasia Marked, Lymphoid Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 3300 PPM 10 161 161 93 1 Depletion Lymphoid Mild Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 3300 PPM 10 162 162 93 1 Depletion Lymphoid Mild Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 10000 PPM 10 174 174 17 1 Depletion Lymphoid Mild Moribund Sacrifice
Hematopoietic System Lymph Node Mandibular 10000 PPM 10 179 179 17 1 Depletion Lymphoid Mild Moribund Sacrifice
Hematopoietic System Lymph Node Mandibular 10000 PPM 10 180 180 17 1 Depletion Lymphoid Mild Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 3300 PPM 10 161 161 93 1 Depletion Lymphoid Moderate Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 3300 PPM 10 162 162 93 1 Depletion Lymphoid Mild Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 3300 PPM 10 163 163 93 1 Depletion Lymphoid Mild Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 10000 PPM 10 173 173 17 1 Depletion Lymphoid Mild Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 10000 PPM 10 174 174 17 1 Depletion Lymphoid Mild Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 10000 PPM 10 175 175 17 1 Depletion Lymphoid Mild Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 10000 PPM 10 177 177 17 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 10000 PPM 10 178 178 17 1 Depletion Lymphoid Mild Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 10000 PPM 10 179 179 17 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 10000 PPM 10 180 180 17 1 Depletion Lymphoid Mild Moribund Sacrifice
Hematopoietic System Spleen 10000 PPM 10 177 177 17 1 Depletion Lymphoid Mild Moribund Sacrifice
Hematopoietic System Spleen 10000 PPM 10 179 179 17 1 Depletion Lymphoid Mild Moribund Sacrifice
Hematopoietic System Spleen 10000 PPM 10 180 180 17 1 Depletion Lymphoid Mild Moribund Sacrifice
Hematopoietic System Thymus 3300 PPM 10 161 161 93 1 Depletion Lymphoid Moderate Terminal Sacrifice
Hematopoietic System Thymus 10000 PPM 10 172 172 17 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Thymus 10000 PPM 10 173 173 17 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Thymus 10000 PPM 10 174 174 17 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Thymus 10000 PPM 10 175 175 17 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Thymus 10000 PPM 10 177 177 17 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Thymus 10000 PPM 10 178 178 17 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Thymus 10000 PPM 10 179 179 17 1 Depletion Lymphoid Moderate Moribund Sacrifice
Hematopoietic System Thymus 10000 PPM 10 180 180 17 1 Depletion Lymphoid Mild Moribund Sacrifice
Hematopoietic System Thymus Untreated Control 10 121 121 93 1 Ectopic Parathyroid Gland Terminal Sacrifice
Respiratory System Lung Alveolar Epith 110 PPM 10 138 138 93 1 Hyperplasia Mild Terminal Sacrifice
Respiratory System Lung Alveolar Epith 330 PPM 10 142 142 93 1 Hyperplasia Marked Terminal Sacrifice
Respiratory System Lung Alveolar Epith 330 PPM 10 144 144 93 1 Hyperplasia Marked Terminal Sacrifice
Respiratory System Lung Alveolar Epith 1100 PPM 10 153 153 93 1 Hyperplasia Mild Terminal Sacrifice
Respiratory System Lung Alveolar Epith 1100 PPM 10 154 154 93 1 Hyperplasia Moderate Terminal Sacrifice
Respiratory System Lung Alveolar Epith 1100 PPM 10 157 157 93 1 Hyperplasia Minimal Terminal Sacrifice
Respiratory System Lung Alveolar Epith 3300 PPM 10 165 165 93 1 Hyperplasia Mild Terminal Sacrifice
Respiratory System Lung Alveolar Epith 3300 PPM 10 167 167 93 1 Hyperplasia Minimal Terminal Sacrifice
Respiratory System Lung Alveolar Epith 3300 PPM 10 168 168 93 1 Hyperplasia Mild Terminal Sacrifice
Respiratory System Lung Alveolar Epith 3300 PPM 10 169 169 93 1 Hyperplasia Minimal Terminal Sacrifice
Respiratory System Lung Alveolar Epith 3300 PPM 10 170 170 93 1 Hyperplasia Moderate Terminal Sacrifice
Respiratory System Lung 3300 PPM 10 166 166 2 1 Foreign Body Mild Natural Death
Respiratory System Lung Untreated Control 10 128 128 93 1 Hemorrhage Minimal Terminal Sacrifice
Respiratory System Lung 110 PPM 10 139 139 93 1 Hemorrhage Minimal Terminal Sacrifice
Respiratory System Lung 110 PPM 10 140 140 93 1 Hemorrhage Minimal Terminal Sacrifice
Respiratory System Lung 330 PPM 10 141 141 84 1 Hemorrhage Minimal Accidentally Killed
Respiratory System Lung 1100 PPM 10 160 160 93 1 Hemorrhage Minimal Terminal Sacrifice
Respiratory System Lung 3300 PPM 10 165 165 93 1 Hemorrhage Mild Terminal Sacrifice
Respiratory System Lung 3300 PPM 10 168 168 93 1 Hemorrhage Minimal Terminal Sacrifice
Respiratory System Lung 10000 PPM 10 179 179 17 1 Hemorrhage Minimal Moribund Sacrifice
Respiratory System Lung 110 PPM 10 138 138 93 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung 330 PPM 10 145 145 93 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung 1100 PPM 10 160 160 93 1 Inflammation Minimal Terminal Sacrifice
Respiratory System Lung 3300 PPM 10 161 161 93 1 Inflammation Minimal Terminal Sacrifice
Respiratory System Lung 3300 PPM 10 163 163 93 1 Inflammation Minimal Terminal Sacrifice
Respiratory System Lung 3300 PPM 10 164 164 93 1 Inflammation Minimal Terminal Sacrifice
Respiratory System Lung 3300 PPM 10 165 165 93 1 Inflammation Minimal Terminal Sacrifice
Respiratory System Lung 3300 PPM 10 167 167 93 1 Inflammation Minimal Terminal Sacrifice
Respiratory System Lung 3300 PPM 10 169 169 93 1 Inflammation Minimal Terminal Sacrifice
Respiratory System Lung 3300 PPM 10 170 170 93 1 Inflammation Minimal Terminal Sacrifice
Respiratory System Lung 10000 PPM 10 171 171 17 1 Inflammation Minimal Moribund Sacrifice
Respiratory System Lung 10000 PPM 10 175 175 17 1 Inflammation Minimal Moribund Sacrifice
Respiratory System Lung 10000 PPM 10 176 176 17 1 Inflammation Minimal Moribund Sacrifice
Respiratory System Lung 10000 PPM 10 179 179 17 1 Inflammation Minimal Moribund Sacrifice
Respiratory System Lung 10000 PPM 10 180 180 17 1 Inflammation Minimal Moribund Sacrifice
Respiratory System Trachea 3300 PPM 10 166 166 2 1 Foreign Body Moderate Natural Death
Urinary System Kidney Untreated Control 10 121 121 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Untreated Control 10 123 123 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Untreated Control 10 127 127 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 330 PPM 10 150 150 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1100 PPM 10 152 152 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1100 PPM 10 155 155 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3300 PPM 10 161 161 93 1 Nephropathy Moderate Terminal Sacrifice
Urinary System Kidney 3300 PPM 10 162 162 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3300 PPM 10 163 163 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3300 PPM 10 164 164 93 1 Nephropathy Mild Terminal Sacrifice
Urinary System Kidney 3300 PPM 10 165 165 93 1 Nephropathy Mild Terminal Sacrifice
Urinary System Kidney 3300 PPM 10 167 167 93 1 Nephropathy Mild Terminal Sacrifice
Urinary System Kidney 3300 PPM 10 168 168 93 1 Nephropathy Mild Terminal Sacrifice
Urinary System Kidney 3300 PPM 10 169 169 93 1 Nephropathy Mild Terminal Sacrifice
Urinary System Kidney 3300 PPM 10 170 170 93 1 Nephropathy Moderate Terminal Sacrifice
Urinary System Kidney 10000 PPM 10 171 171 17 1 Nephropathy Minimal Moribund Sacrifice
Urinary System Kidney 10000 PPM 10 174 174 17 1 Nephropathy Minimal Moribund Sacrifice