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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: alpha-Methylstyrene
CASRN: ="98-83-9"
Study Number: C88006B
Exposure Route: RESPIRATORY EXPOSURE WHOLE BODY
TDMS Number: 8800601
Sex: Male
Strain and Species: F 344/N Rats

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Vehicle Control 10 2 10 93 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 75 PPM 10 5 202 93 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 600 PPM 10 18 807 93 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Mesentery Fat 600 PPM 1 17 802 93 1 Necrosis Moderate Terminal Sacrifice
Alimentary System Pancreas 1000 PPM 10 21 1001 93 1 Atrophy Minimal Terminal Sacrifice
Genital System Testes Vehicle Control 10 2 9 93 1 Degeneration Moderate Terminal Sacrifice
Hematopoietic System Lymph Node Mediastinal 75 PPM 1 6 206 93 1 Hemorrhage Marked Terminal Sacrifice
Respiratory System Larynx 1000 PPM 10 21 1002 93 1 Foreign Body Terminal Sacrifice
Special Senses System Eye 75 PPM 1 5 205 93 1 Hemorrhage Marked Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule Vehicle Control 10 1 1 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule Vehicle Control 10 1 2 93 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule Vehicle Control 10 1 3 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule Vehicle Control 10 1 4 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule Vehicle Control 10 1 5 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule Vehicle Control 10 2 10 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule Vehicle Control 10 2 6 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule Vehicle Control 10 2 7 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule Vehicle Control 10 2 9 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 75 PPM 10 5 201 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 75 PPM 10 5 202 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 75 PPM 10 5 203 93 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 75 PPM 10 5 204 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 75 PPM 10 5 205 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 75 PPM 10 6 206 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 75 PPM 10 6 207 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 75 PPM 10 6 208 93 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 75 PPM 10 6 209 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 75 PPM 10 6 210 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 150 PPM 10 10 406 93 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 150 PPM 10 10 407 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 150 PPM 10 10 408 93 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 150 PPM 10 10 409 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 150 PPM 10 10 410 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 150 PPM 10 9 401 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 150 PPM 10 9 402 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 150 PPM 10 9 403 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 150 PPM 10 9 404 93 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 150 PPM 10 9 405 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 300 PPM 10 13 601 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 300 PPM 10 13 602 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 300 PPM 10 13 603 93 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 300 PPM 10 13 604 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 300 PPM 10 13 605 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 300 PPM 10 14 606 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 300 PPM 10 14 607 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 300 PPM 10 14 608 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 300 PPM 10 14 609 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 300 PPM 10 14 610 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 600 PPM 10 17 801 93 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 600 PPM 10 17 802 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 600 PPM 10 17 803 93 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 600 PPM 10 17 804 93 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 600 PPM 10 17 805 93 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 600 PPM 10 18 806 93 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 600 PPM 10 18 807 93 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 600 PPM 10 18 808 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 600 PPM 10 18 809 93 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 600 PPM 10 18 810 93 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 1000 PPM 10 21 1001 93 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 1000 PPM 10 21 1002 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 1000 PPM 10 21 1003 93 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 1000 PPM 10 21 1004 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 1000 PPM 10 21 1005 93 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 1000 PPM 10 22 1006 93 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 1000 PPM 10 22 1007 93 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 1000 PPM 10 22 1008 93 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 1000 PPM 10 22 1009 93 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 1000 PPM 10 22 1010 93 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule Vehicle Control 10 1 1 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule Vehicle Control 10 1 2 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule Vehicle Control 10 1 3 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule Vehicle Control 10 1 5 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule Vehicle Control 10 2 10 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule Vehicle Control 10 2 6 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule Vehicle Control 10 2 7 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule Vehicle Control 10 2 8 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 75 PPM 10 5 201 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 75 PPM 10 5 204 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 75 PPM 10 5 205 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 75 PPM 10 6 206 93 1 Regeneration Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 150 PPM 10 10 407 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 150 PPM 10 10 408 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 150 PPM 10 10 409 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 150 PPM 10 10 410 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 150 PPM 10 9 401 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 150 PPM 10 9 402 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 150 PPM 10 9 403 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 150 PPM 10 9 404 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 150 PPM 10 9 405 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 300 PPM 10 13 601 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 300 PPM 10 13 604 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 300 PPM 10 14 606 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 300 PPM 10 14 609 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 300 PPM 10 14 610 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 600 PPM 10 17 801 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 600 PPM 10 17 802 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 600 PPM 10 17 803 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 600 PPM 10 17 805 93 1 Regeneration Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 600 PPM 10 18 806 93 1 Regeneration Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 600 PPM 10 18 807 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 600 PPM 10 18 808 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 600 PPM 10 18 809 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 600 PPM 10 18 810 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 1000 PPM 10 21 1003 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 1000 PPM 10 21 1004 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 1000 PPM 10 21 1005 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 1000 PPM 10 22 1006 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 1000 PPM 10 22 1007 93 1 Regeneration Mild Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 1000 PPM 10 22 1008 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 1000 PPM 10 22 1009 93 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Cortex, Renal Tubule 1000 PPM 10 22 1010 93 1 Regeneration Minimal Terminal Sacrifice