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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: m-Chloroaniline
CASRN: ="108-42-9"
Study Number: C61529B
Exposure Route: GAVAGE
TDMS Number: 6152902
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Esophagus 20 MG/KG 3 24 24 9 1 Foreign Body Dosing Accident
Alimentary System Esophagus Vehicle Control 10 2 2 9 1 Inflammation Moderate, Suppurative Dosing Accident
Alimentary System Esophagus Vehicle Control 10 2 2 9 1 Perforation Dosing Accident
Alimentary System Liver Kupffer Cell 80 MG/KG 3 42 42 93 1 Pigmentation Minimal Terminal Sacrifice
Alimentary System Liver Kupffer Cell 80 MG/KG 3 43 43 93 1 Pigmentation Minimal Terminal Sacrifice
Alimentary System Liver Kupffer Cell 80 MG/KG 3 44 44 93 1 Pigmentation Minimal Terminal Sacrifice
Alimentary System Liver Kupffer Cell 160 MG/KG 10 52 52 93 1 Pigmentation Mild Terminal Sacrifice
Alimentary System Liver Kupffer Cell 160 MG/KG 10 53 53 93 1 Pigmentation Mild Terminal Sacrifice
Alimentary System Liver Kupffer Cell 160 MG/KG 10 54 54 93 1 Pigmentation Mild Terminal Sacrifice
Alimentary System Liver Kupffer Cell 160 MG/KG 10 55 55 93 1 Pigmentation Minimal Terminal Sacrifice
Alimentary System Liver Kupffer Cell 160 MG/KG 10 56 56 93 1 Pigmentation Mild Terminal Sacrifice
Alimentary System Liver Kupffer Cell 160 MG/KG 10 57 57 93 1 Pigmentation Minimal Terminal Sacrifice
Alimentary System Liver Kupffer Cell 160 MG/KG 10 58 58 93 1 Pigmentation Minimal Terminal Sacrifice
Alimentary System Liver Kupffer Cell 160 MG/KG 10 59 59 93 1 Pigmentation Minimal Terminal Sacrifice
Alimentary System Liver Kupffer Cell 160 MG/KG 10 60 60 93 1 Pigmentation Minimal Terminal Sacrifice
Alimentary System Liver 160 MG/KG 10 52 52 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Alimentary System Liver 160 MG/KG 10 53 53 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Alimentary System Liver 160 MG/KG 10 54 54 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Alimentary System Liver 160 MG/KG 10 55 55 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Alimentary System Liver 160 MG/KG 10 56 56 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Alimentary System Liver 160 MG/KG 10 57 57 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Alimentary System Liver 160 MG/KG 10 58 58 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Alimentary System Liver 160 MG/KG 10 60 60 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 160 MG/KG 10 54 54 93 1 Degeneration Minimal Terminal Sacrifice
Cardiovascular System Heart Pericardium Vehicle Control 10 2 2 9 1 Inflammation Mild, Suppurative Dosing Accident
Cardiovascular System Heart Pericardium 20 MG/KG 3 27 27 5 1 Inflammation Mild, Suppurative Dosing Accident
Cardiovascular System Heart 20 MG/KG 3 24 24 9 1 Inflammation Mild, Suppurative Dosing Accident
Cardiovascular System Heart 20 MG/KG 3 28 28 9 1 Inflammation Mild, Suppurative Dosing Accident
Hematopoietic System Bone Marrow Erythroid Cell 160 MG/KG 10 53 53 93 1 Hyperplasia Minimal Terminal Sacrifice
Hematopoietic System Bone Marrow Erythroid Cell 160 MG/KG 10 56 56 93 1 Hyperplasia Mild Terminal Sacrifice
Hematopoietic System Bone Marrow Erythroid Cell 160 MG/KG 10 57 57 93 1 Hyperplasia Minimal Terminal Sacrifice
Hematopoietic System Bone Marrow Erythroid Cell 160 MG/KG 10 60 60 93 1 Hyperplasia Minimal Terminal Sacrifice
Hematopoietic System Bone Marrow 40 MG/KG 10 31 31 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 40 MG/KG 10 32 32 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 40 MG/KG 10 33 33 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 40 MG/KG 10 34 34 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 40 MG/KG 10 35 35 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 40 MG/KG 10 36 36 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 40 MG/KG 10 37 37 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 40 MG/KG 10 38 38 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 40 MG/KG 10 39 39 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 40 MG/KG 10 40 40 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 80 MG/KG 10 41 41 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 80 MG/KG 10 42 42 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 80 MG/KG 10 43 43 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 80 MG/KG 10 44 44 93 1 Pigmentation Moderate, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 80 MG/KG 10 45 45 93 1 Pigmentation Moderate, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 80 MG/KG 10 46 46 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 80 MG/KG 10 47 47 93 1 Pigmentation Moderate, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 80 MG/KG 10 48 48 93 1 Pigmentation Moderate, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 80 MG/KG 10 49 49 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 80 MG/KG 10 50 50 93 1 Pigmentation Moderate, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 160 MG/KG 10 51 51 93 1 Pigmentation Marked, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 160 MG/KG 10 52 52 93 1 Pigmentation Marked, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 160 MG/KG 10 53 53 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 160 MG/KG 10 54 54 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 160 MG/KG 10 55 55 93 1 Pigmentation Marked, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 160 MG/KG 10 56 56 93 1 Pigmentation Marked, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 160 MG/KG 10 57 57 93 1 Pigmentation Marked, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 160 MG/KG 10 58 58 93 1 Pigmentation Marked, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 160 MG/KG 10 59 59 93 1 Pigmentation Marked, Hemosiderin Terminal Sacrifice
Hematopoietic System Bone Marrow 160 MG/KG 10 60 60 93 1 Pigmentation Marked, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 20 MG/KG 10 24 24 9 1 Hematopoietic Cell Proliferation Minimal Dosing Accident
Hematopoietic System Spleen 20 MG/KG 10 23 23 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 20 MG/KG 10 25 25 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 31 31 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 32 32 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 33 33 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 34 34 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 35 35 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 36 36 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 37 37 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 38 38 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 39 39 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 40 40 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 41 41 93 1 Hematopoietic Cell Proliferation Marked Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 42 42 93 1 Hematopoietic Cell Proliferation Moderate Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 43 43 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 44 44 93 1 Hematopoietic Cell Proliferation Moderate Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 45 45 93 1 Hematopoietic Cell Proliferation Moderate Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 46 46 93 1 Hematopoietic Cell Proliferation Moderate Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 47 47 93 1 Hematopoietic Cell Proliferation Moderate Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 48 48 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 49 49 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 50 50 93 1 Hematopoietic Cell Proliferation Moderate Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 51 51 93 1 Hematopoietic Cell Proliferation Marked Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 52 52 93 1 Hematopoietic Cell Proliferation Marked Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 53 53 93 1 Hematopoietic Cell Proliferation Marked Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 54 54 93 1 Hematopoietic Cell Proliferation Marked Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 55 55 93 1 Hematopoietic Cell Proliferation Moderate Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 56 56 93 1 Hematopoietic Cell Proliferation Marked Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 57 57 93 1 Hematopoietic Cell Proliferation Marked Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 58 58 93 1 Hematopoietic Cell Proliferation Marked Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 59 59 93 1 Hematopoietic Cell Proliferation Moderate Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 60 60 93 1 Hematopoietic Cell Proliferation Marked Terminal Sacrifice
Hematopoietic System Spleen 10 MG/KG 10 16 16 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 20 MG/KG 10 21 21 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 20 MG/KG 10 22 22 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 20 MG/KG 10 23 23 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 20 MG/KG 10 26 26 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 31 31 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 32 32 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 33 33 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 34 34 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 35 35 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 36 36 93 1 Pigmentation Moderate, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 37 37 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 38 38 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 39 39 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 40 40 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 41 41 93 1 Pigmentation Moderate, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 42 42 93 1 Pigmentation Moderate, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 43 43 93 1 Pigmentation Moderate, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 44 44 93 1 Pigmentation Moderate, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 45 45 93 1 Pigmentation Marked, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 46 46 93 1 Pigmentation Moderate, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 47 47 93 1 Pigmentation Moderate, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 48 48 93 1 Pigmentation Moderate, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 49 49 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 50 50 93 1 Pigmentation Moderate, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 51 51 93 1 Pigmentation Marked, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 52 52 93 1 Pigmentation Marked, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 53 53 93 1 Pigmentation Marked, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 54 54 93 1 Pigmentation Marked, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 55 55 93 1 Pigmentation Marked, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 56 56 93 1 Pigmentation Marked, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 57 57 93 1 Pigmentation Marked, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 58 58 93 1 Pigmentation Marked, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 59 59 93 1 Pigmentation Marked, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 60 60 93 1 Pigmentation Marked, Hemosiderin Terminal Sacrifice
Respiratory System Lung Serosa Vehicle Control 10 2 2 9 1 Inflammation Marked, Suppurative Dosing Accident
Respiratory System Lung Serosa 20 MG/KG 3 24 24 9 1 Inflammation Moderate, Suppurative Dosing Accident
Respiratory System Lung Serosa 20 MG/KG 3 27 27 5 1 Inflammation Moderate, Suppurative Dosing Accident
Respiratory System Lung Serosa 20 MG/KG 3 28 28 9 1 Inflammation Moderate, Suppurative Dosing Accident
Respiratory System Lung Vehicle Control 10 2 2 9 1 Foreign Body Dosing Accident
Respiratory System Lung 20 MG/KG 3 24 24 9 1 Foreign Body Dosing Accident