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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: o-Chloroaniline
CASRN: ="95-51-2"
Study Number: C91001
Exposure Route: GAVAGE
TDMS Number: 9100101
Sex: Male
Strain and Species: F 344/N Rats

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Vehicle Control 10 1 4 93 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 160 MG/KG 10 11 51 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Alimentary System Liver 160 MG/KG 10 11 52 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Alimentary System Liver 160 MG/KG 10 11 53 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Alimentary System Liver 160 MG/KG 10 11 54 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Alimentary System Liver 160 MG/KG 10 11 55 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Alimentary System Liver 160 MG/KG 10 12 56 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Alimentary System Liver 160 MG/KG 10 12 57 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Alimentary System Liver 160 MG/KG 10 12 58 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Alimentary System Liver 160 MG/KG 10 12 59 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Alimentary System Liver 160 MG/KG 10 12 60 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Cardiovascular System Heart Myocardium Vehicle Control 10 1 3 93 1 Degeneration Minimal, Focal, Chronic Terminal Sacrifice
Cardiovascular System Heart Myocardium Vehicle Control 10 2 6 93 1 Degeneration Minimal, Focal, Chronic Terminal Sacrifice
Cardiovascular System Heart Myocardium 160 MG/KG 10 11 53 93 1 Degeneration Minimal, Focal, Chronic Terminal Sacrifice
Cardiovascular System Heart Myocardium 160 MG/KG 10 12 56 93 1 Degeneration Mild, Focal, Chronic Terminal Sacrifice
Genital System Preputial Gland Vehicle Control 10 1 3 93 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Preputial Gland Vehicle Control 10 1 5 93 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Preputial Gland Vehicle Control 10 2 10 93 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Preputial Gland Vehicle Control 10 2 6 93 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Preputial Gland Vehicle Control 10 2 8 93 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Preputial Gland Vehicle Control 10 2 9 93 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Preputial Gland 160 MG/KG 10 11 53 93 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Preputial Gland 160 MG/KG 10 11 54 93 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Preputial Gland 160 MG/KG 10 11 55 93 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Preputial Gland 160 MG/KG 10 12 56 93 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Preputial Gland 160 MG/KG 10 12 57 93 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Preputial Gland 160 MG/KG 10 12 58 93 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Hematopoietic System Bone Marrow Erythroid Cell 40 MG/KG 10 8 40 12 1 Hyperplasia Mild Natural Death
Hematopoietic System Bone Marrow Erythroid Cell 80 MG/KG 10 10 46 93 1 Hyperplasia Mild Terminal Sacrifice
Hematopoietic System Bone Marrow Erythroid Cell 80 MG/KG 10 10 47 93 1 Hyperplasia Minimal Terminal Sacrifice
Hematopoietic System Bone Marrow Erythroid Cell 80 MG/KG 10 10 48 93 1 Hyperplasia Mild Terminal Sacrifice
Hematopoietic System Bone Marrow Erythroid Cell 80 MG/KG 10 10 49 93 1 Hyperplasia Minimal Terminal Sacrifice
Hematopoietic System Bone Marrow Erythroid Cell 80 MG/KG 10 10 50 93 1 Hyperplasia Minimal Terminal Sacrifice
Hematopoietic System Bone Marrow Erythroid Cell 80 MG/KG 10 9 41 93 1 Hyperplasia Minimal Terminal Sacrifice
Hematopoietic System Bone Marrow Erythroid Cell 80 MG/KG 10 9 42 93 1 Hyperplasia Mild Terminal Sacrifice
Hematopoietic System Bone Marrow Erythroid Cell 80 MG/KG 10 9 43 93 1 Hyperplasia Mild Terminal Sacrifice
Hematopoietic System Bone Marrow Erythroid Cell 80 MG/KG 10 9 44 93 1 Hyperplasia Mild Terminal Sacrifice
Hematopoietic System Bone Marrow Erythroid Cell 80 MG/KG 10 9 45 93 1 Hyperplasia Mild Terminal Sacrifice
Hematopoietic System Bone Marrow Erythroid Cell 160 MG/KG 10 11 51 93 1 Hyperplasia Mild Terminal Sacrifice
Hematopoietic System Bone Marrow Erythroid Cell 160 MG/KG 10 11 52 93 1 Hyperplasia Mild Terminal Sacrifice
Hematopoietic System Bone Marrow Erythroid Cell 160 MG/KG 10 11 53 93 1 Hyperplasia Mild Terminal Sacrifice
Hematopoietic System Bone Marrow Erythroid Cell 160 MG/KG 10 11 54 93 1 Hyperplasia Mild Terminal Sacrifice
Hematopoietic System Bone Marrow Erythroid Cell 160 MG/KG 10 11 55 93 1 Hyperplasia Mild Terminal Sacrifice
Hematopoietic System Bone Marrow Erythroid Cell 160 MG/KG 10 12 56 93 1 Hyperplasia Mild Terminal Sacrifice
Hematopoietic System Bone Marrow Erythroid Cell 160 MG/KG 10 12 57 93 1 Hyperplasia Mild Terminal Sacrifice
Hematopoietic System Bone Marrow Erythroid Cell 160 MG/KG 10 12 58 93 1 Hyperplasia Mild Terminal Sacrifice
Hematopoietic System Bone Marrow Erythroid Cell 160 MG/KG 10 12 59 93 1 Hyperplasia Mild Terminal Sacrifice
Hematopoietic System Bone Marrow Erythroid Cell 160 MG/KG 10 12 60 93 1 Hyperplasia Mild Terminal Sacrifice
Hematopoietic System Spleen Capsule 80 MG/KG 10 10 46 93 1 Fibrosis Minimal Terminal Sacrifice
Hematopoietic System Spleen Capsule 80 MG/KG 10 10 47 93 1 Fibrosis Minimal Terminal Sacrifice
Hematopoietic System Spleen Capsule 80 MG/KG 10 10 48 93 1 Fibrosis Minimal Terminal Sacrifice
Hematopoietic System Spleen Capsule 80 MG/KG 10 10 49 93 1 Fibrosis Minimal Terminal Sacrifice
Hematopoietic System Spleen Capsule 80 MG/KG 10 10 50 93 1 Fibrosis Minimal Terminal Sacrifice
Hematopoietic System Spleen Capsule 80 MG/KG 10 9 41 93 1 Fibrosis Minimal Terminal Sacrifice
Hematopoietic System Spleen Capsule 80 MG/KG 10 9 42 93 1 Fibrosis Minimal Terminal Sacrifice
Hematopoietic System Spleen Capsule 80 MG/KG 10 9 43 93 1 Fibrosis Minimal Terminal Sacrifice
Hematopoietic System Spleen Capsule 80 MG/KG 10 9 44 93 1 Fibrosis Minimal Terminal Sacrifice
Hematopoietic System Spleen Capsule 80 MG/KG 10 9 45 93 1 Fibrosis Minimal Terminal Sacrifice
Hematopoietic System Spleen Capsule 160 MG/KG 10 11 52 93 1 Fibrosis Mild Terminal Sacrifice
Hematopoietic System Spleen Capsule 160 MG/KG 10 11 53 93 1 Fibrosis Mild Terminal Sacrifice
Hematopoietic System Spleen Capsule 160 MG/KG 10 11 54 93 1 Fibrosis Mild Terminal Sacrifice
Hematopoietic System Spleen Capsule 160 MG/KG 10 11 55 93 1 Fibrosis Mild Terminal Sacrifice
Hematopoietic System Spleen Capsule 160 MG/KG 10 12 56 93 1 Fibrosis Mild Terminal Sacrifice
Hematopoietic System Spleen Capsule 160 MG/KG 10 12 57 93 1 Fibrosis Mild Terminal Sacrifice
Hematopoietic System Spleen Capsule 160 MG/KG 10 12 58 93 1 Fibrosis Mild Terminal Sacrifice
Hematopoietic System Spleen Capsule 160 MG/KG 10 12 59 93 1 Fibrosis Mild Terminal Sacrifice
Hematopoietic System Spleen Capsule 160 MG/KG 10 12 60 93 1 Fibrosis Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 10 46 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 10 47 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 10 48 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 10 49 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 10 50 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 9 41 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 9 42 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 9 43 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 9 44 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 9 45 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 11 51 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 11 52 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 11 53 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 11 54 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 11 55 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 12 56 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 12 57 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 12 58 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 12 59 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 12 60 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 11 51 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 11 52 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 11 53 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 11 54 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 11 55 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 12 56 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 12 57 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 12 58 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 12 59 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Urinary System Kidney Cortex 160 MG/KG 10 11 51 93 1 Pigmentation Mild, Diffuse, Hemosiderin Terminal Sacrifice
Urinary System Kidney Cortex 160 MG/KG 10 11 52 93 1 Pigmentation Mild, Diffuse, Hemosiderin Terminal Sacrifice
Urinary System Kidney Cortex 160 MG/KG 10 11 53 93 1 Pigmentation Minimal, Diffuse, Hemosiderin Terminal Sacrifice
Urinary System Kidney Cortex 160 MG/KG 10 11 54 93 1 Pigmentation Mild, Diffuse, Hemosiderin Terminal Sacrifice
Urinary System Kidney Cortex 160 MG/KG 10 11 55 93 1 Pigmentation Minimal, Diffuse, Hemosiderin Terminal Sacrifice
Urinary System Kidney Cortex 160 MG/KG 10 12 56 93 1 Pigmentation Mild, Diffuse, Hemosiderin Terminal Sacrifice
Urinary System Kidney Cortex 160 MG/KG 10 12 57 93 1 Pigmentation Minimal, Diffuse, Hemosiderin Terminal Sacrifice
Urinary System Kidney Cortex 160 MG/KG 10 12 58 93 1 Pigmentation Minimal, Diffuse, Hemosiderin Terminal Sacrifice
Urinary System Kidney Cortex 160 MG/KG 10 12 59 93 1 Pigmentation Minimal, Diffuse, Hemosiderin Terminal Sacrifice
Urinary System Kidney Cortex 160 MG/KG 10 12 60 93 1 Pigmentation Minimal, Diffuse, Hemosiderin Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 1 1 93 1 Mineralization Minimal, Focal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 1 2 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 1 3 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 1 4 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 1 5 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 2 10 93 1 Mineralization Mild, Diffuse Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 2 6 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 2 7 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 2 8 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 2 9 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 10 MG/KG 10 3 11 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 10 MG/KG 10 3 12 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 10 MG/KG 10 3 13 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 10 MG/KG 10 3 14 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 10 MG/KG 10 3 15 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 10 MG/KG 10 4 16 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 10 MG/KG 10 4 17 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 10 MG/KG 10 4 18 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 10 MG/KG 10 4 19 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 10 MG/KG 10 4 20 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 20 MG/KG 10 5 21 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 20 MG/KG 10 5 22 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 20 MG/KG 10 5 23 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 20 MG/KG 10 5 24 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 20 MG/KG 10 5 25 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 20 MG/KG 10 6 26 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 20 MG/KG 10 6 27 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 20 MG/KG 10 6 28 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 20 MG/KG 10 6 29 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 20 MG/KG 10 6 30 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 40 MG/KG 10 8 40 12 1 Mineralization Minimal, Diffuse Natural Death
Urinary System Kidney 40 MG/KG 10 7 31 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 40 MG/KG 10 7 32 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 40 MG/KG 10 7 33 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 40 MG/KG 10 7 34 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 40 MG/KG 10 7 35 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 40 MG/KG 10 8 36 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 40 MG/KG 10 8 37 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 40 MG/KG 10 8 38 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 40 MG/KG 10 8 39 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 80 MG/KG 10 10 46 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 80 MG/KG 10 10 47 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 80 MG/KG 10 10 48 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 80 MG/KG 10 10 49 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 80 MG/KG 10 10 50 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 80 MG/KG 10 9 41 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 80 MG/KG 10 9 42 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 80 MG/KG 10 9 43 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 80 MG/KG 10 9 44 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 80 MG/KG 10 9 45 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 160 MG/KG 10 11 51 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 160 MG/KG 10 11 52 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 160 MG/KG 10 11 54 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 160 MG/KG 10 11 55 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 160 MG/KG 10 12 56 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 160 MG/KG 10 12 57 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 160 MG/KG 10 12 58 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice
Urinary System Kidney 160 MG/KG 10 12 59 93 1 Mineralization Mild, Diffuse Terminal Sacrifice
Urinary System Kidney 160 MG/KG 10 12 60 93 1 Mineralization Minimal, Diffuse Terminal Sacrifice