If this is the first time you are viewing this file, please choose 'Save As' from the 'File' menu and resave this file as an Excel file type. This will greatly speed up future viewings of this file.

Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: o-Chloroaniline
CASRN: ="95-51-2"
Study Number: C91001
Exposure Route: GAVAGE
TDMS Number: 9100102
Sex: Female
Strain and Species: B6C3F1 Mice

Female Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Endocrine System Parathyroid Gland 160 MG/KG 10 112 112 86 1 Cyst Minimal Dosing Accident
Endocrine System Thyroid Gland 160 MG/KG 10 118 118 93 1 Cyst Minimal Terminal Sacrifice
Endocrine System Thyroid Gland 20 MG/KG 1 87 87 93 1 Inflammation Minimal, Granulomatous Dosing Accident
Genital System Ovary 40 MG/KG 1 96 96 93 1 Cyst Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 101 101 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 102 102 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 103 103 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 104 104 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 105 105 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 107 107 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 108 108 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 109 109 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 110 110 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 112 112 86 1 Hematopoietic Cell Proliferation Minimal Dosing Accident
Hematopoietic System Spleen 160 MG/KG 10 111 111 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 113 113 93 1 Hematopoietic Cell Proliferation Moderate Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 114 114 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 115 115 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 116 116 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 117 117 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 118 118 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 119 119 93 1 Hematopoietic Cell Proliferation Moderate Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 120 120 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 100 100 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 91 91 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 92 92 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 93 93 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 94 94 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 95 95 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 96 96 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 97 97 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 98 98 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 99 99 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 101 101 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 102 102 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 104 104 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 105 105 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 106 106 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 107 107 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 108 108 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 109 109 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 110 110 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 112 112 86 1 Pigmentation Mild, Hemosiderin Dosing Accident
Hematopoietic System Spleen 160 MG/KG 10 111 111 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 113 113 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 114 114 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 115 115 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 116 116 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 117 117 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 118 118 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 119 119 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 120 120 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Thymus 160 MG/KG 10 112 112 86 1 Hemorrhage Mild Dosing Accident
Hematopoietic System Thymus 20 MG/KG 1 87 87 93 1 Inflammation Mild, Granulomatous Dosing Accident
Respiratory System Lung 160 MG/KG 10 112 112 86 1 Hemorrhage Moderate, Focal Dosing Accident