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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: o-Chloroaniline
CASRN: ="95-51-2"
Study Number: C91001
Exposure Route: GAVAGE
TDMS Number: 9100102
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Esophagus 10 MG/KG 1 11 11 9 1 Inflammation Moderate, Suppurative Dosing Accident
Hematopoietic System Spleen 40 MG/KG 10 33 33 93 1 Hematopoietic Cell Proliferation Minimal Natural Death
Hematopoietic System Spleen 40 MG/KG 10 32 32 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 34 34 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 36 36 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 38 38 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 40 MG/KG 10 39 39 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 41 41 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 42 42 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 43 43 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 44 44 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 45 45 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 46 46 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 47 47 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 48 48 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 49 49 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 50 50 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 59 59 93 1 Hematopoietic Cell Proliferation Minimal Natural Death
Hematopoietic System Spleen 160 MG/KG 10 51 51 93 1 Hematopoietic Cell Proliferation Moderate Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 52 52 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 53 53 93 1 Hematopoietic Cell Proliferation Moderate Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 54 54 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 55 55 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 56 56 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 57 57 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 58 58 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 60 60 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 10 47 47 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 59 59 93 1 Pigmentation Minimal, Hemosiderin Natural Death
Hematopoietic System Spleen 160 MG/KG 10 51 51 93 1 Pigmentation Moderate, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 52 52 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 53 53 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 54 54 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 55 55 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 56 56 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 57 57 93 1 Pigmentation Mild, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 58 58 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 160 MG/KG 10 60 60 93 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Thymus 10 MG/KG 1 11 11 9 1 Inflammation Mild, Suppurative Dosing Accident
Respiratory System Pleura 10 MG/KG 1 11 11 9 1 Inflammation Minimal, Suppurative Dosing Accident
Urinary System Kidney Vehicle Control 10 1 1 93 1 Nephropathy Minimal Terminal Sacrifice