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Current Search Critera

Short-Term Study Individual Animal Clinical Observations

Study Information:

Chemical Name: 3'-Azido-3'-deoxythymidine (AIDS)
CASRN: ="30516-87-1"
Study Number: C88072
Exposure Route: GAVAGE
TDMS Number: 8807202
Sex: Female
Strain and Species: F 344/N Rats

Animal Number Dose Group Clinical Observation Qualifier Incident Number Observation Date First Dose Date Days On Study Removal Observation
57 Vehicle Control Alopecia 07/19/1989 04/17/89 94.00 Yes
63 125 MG/KG Fractured Appendage Tail 05/09/1989 04/17/89 23.00 No
63 125 MG/KG Fractured Appendage Tail 05/16/1989 04/17/89 30.00 No
63 125 MG/KG Fractured Appendage Tail 05/23/1989 04/17/89 37.00 No
63 125 MG/KG Fractured Appendage Tail 05/30/1989 04/17/89 44.00 No
63 125 MG/KG Fractured Appendage Tail 06/06/1989 04/17/89 51.00 No
63 125 MG/KG Fractured Appendage Tail 06/13/1989 04/17/89 58.00 No
63 125 MG/KG Fractured Appendage Tail 06/20/1989 04/17/89 65.00 No
63 125 MG/KG Fractured Appendage Tail 06/27/1989 04/17/89 72.00 No
63 125 MG/KG Fractured Appendage Tail 07/03/1989 04/17/89 78.00 No
63 125 MG/KG Fractured Appendage Tail 07/11/1989 04/17/89 86.00 No
63 125 MG/KG Fractured Appendage Tail 07/18/1989 04/17/89 93.00 No
63 125 MG/KG Fractured Appendage Tail 07/19/1989 04/17/89 94.00 Yes
72 250 MG/KG Opacity 05/16/1989 04/17/89 30.00 No
72 250 MG/KG Micro-Ophthalmia 05/23/1989 04/17/89 37.00 No
72 250 MG/KG Micro-Ophthalmia 05/30/1989 04/17/89 44.00 No
72 250 MG/KG Micro-Ophthalmia 06/06/1989 04/17/89 51.00 No
72 250 MG/KG Micro-Ophthalmia 06/13/1989 04/17/89 58.00 No
72 250 MG/KG Micro-Ophthalmia 06/20/1989 04/17/89 65.00 No
72 250 MG/KG Micro-Ophthalmia 06/27/1989 04/17/89 72.00 No
72 250 MG/KG Micro-Ophthalmia 07/03/1989 04/17/89 78.00 No
72 250 MG/KG Micro-Ophthalmia 07/11/1989 04/17/89 86.00 No
72 250 MG/KG Reddened Eye 07/11/1989 04/17/89 86.00 No
72 250 MG/KG Micro-Ophthalmia 07/18/1989 04/17/89 93.00 No
72 250 MG/KG Reddened Eye 07/18/1989 04/17/89 93.00 No
72 250 MG/KG Micro-Ophthalmia 07/19/1989 04/17/89 94.00 Yes
81 500 MG/KG Alopecia 05/23/1989 04/17/89 37.00 No
81 500 MG/KG Alopecia 05/30/1989 04/17/89 44.00 No
81 500 MG/KG Alopecia 06/06/1989 04/17/89 51.00 No
81 500 MG/KG Alopecia 06/13/1989 04/17/89 58.00 No
81 500 MG/KG Alopecia 06/20/1989 04/17/89 65.00 No
81 500 MG/KG Alopecia 06/27/1989 04/17/89 72.00 No
81 500 MG/KG Alopecia 07/03/1989 04/17/89 78.00 No
81 500 MG/KG Alopecia 07/11/1989 04/17/89 86.00 No
81 500 MG/KG Alopecia 07/18/1989 04/17/89 93.00 No
81 500 MG/KG Alopecia 07/19/1989 04/17/89 94.00 Yes
82 500 MG/KG Alopecia 06/06/1989 04/17/89 51.00 No
82 500 MG/KG Alopecia 06/13/1989 04/17/89 58.00 No
82 500 MG/KG Alopecia 06/20/1989 04/17/89 65.00 No
82 500 MG/KG Alopecia 06/27/1989 04/17/89 72.00 No
82 500 MG/KG Alopecia 07/03/1989 04/17/89 78.00 No
82 500 MG/KG Alopecia 07/11/1989 04/17/89 86.00 No
82 500 MG/KG Alopecia 07/18/1989 04/17/89 93.00 No
82 500 MG/KG Alopecia 07/19/1989 04/17/89 94.00 Yes
84 500 MG/KG Alopecia 06/06/1989 04/17/89 51.00 No
84 500 MG/KG Alopecia 06/13/1989 04/17/89 58.00 No
84 500 MG/KG Alopecia 06/20/1989 04/17/89 65.00 No
84 500 MG/KG Alopecia 06/27/1989 04/17/89 72.00 No
84 500 MG/KG Alopecia 07/11/1989 04/17/89 86.00 No
84 500 MG/KG Alopecia 07/18/1989 04/17/89 93.00 No
84 500 MG/KG Alopecia 07/19/1989 04/17/89 94.00 Yes
85 500 MG/KG Alopecia 06/13/1989 04/17/89 58.00 No
85 500 MG/KG Alopecia 06/20/1989 04/17/89 65.00 No
85 500 MG/KG Alopecia 06/27/1989 04/17/89 72.00 No
85 500 MG/KG Alopecia 07/03/1989 04/17/89 78.00 No
85 500 MG/KG Alopecia 07/11/1989 04/17/89 86.00 No
85 500 MG/KG Alopecia 07/18/1989 04/17/89 93.00 No
85 500 MG/KG Alopecia 07/19/1989 04/17/89 94.00 Yes
89 500 MG/KG Micro-Ophthalmia 07/11/1989 04/17/89 86.00 No
89 500 MG/KG Micro-Ophthalmia 07/18/1989 04/17/89 93.00 No
89 500 MG/KG Micro-Ophthalmia 07/19/1989 04/17/89 94.00 Yes
95 1000 MG/KG Head Tilted 07/19/1989 04/17/89 94.00 Yes
97 1000 MG/KG Rales 06/13/1989 04/17/89 58.00 No