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Current Search Critera

Long-Term Study Individual Animal Clinical Observations

Study Information:

Chemical Name: 5-(Hydroxymethyl)-2-furfural
CASRN: ="67-47-0"
Study Number: C95011B
Exposure Route: GAVAGE
TDMS Number: 9501106
Sex: Female
Strain and Species: B6C3F1 Mice

Animal Number Dose Group Clinical Observation Qualifier Incident Number Observation Date First Dose Date Days On Study Removal Observation
213 Vehicle Control Paralysis 01/10/2003 08/08/01 521.00 Yes
221 Vehicle Control Mass Torso/Lateral, Large (16mm And Larger) 1 07/09/2003 08/08/01 701.00 No
221 Vehicle Control Mass Torso/Lateral, Large (16mm And Larger) 1 07/24/2003 08/08/01 716.00 Yes
222 Vehicle Control Thin 07/08/2003 08/08/01 700.00 Yes
222 Vehicle Control Head Tilt 07/08/2003 08/08/01 700.00 Yes
222 Vehicle Control Ataxia 07/08/2003 08/08/01 700.00 Yes
224 Vehicle Control Ulcer/Abscess Torso/Ventral 1 01/23/2002 08/08/01 169.00 No
226 Vehicle Control Thin 03/31/2003 08/08/01 601.00 Yes
226 Vehicle Control Abnormal Breathing 03/31/2003 08/08/01 601.00 Yes
226 Vehicle Control Lethargic 03/31/2003 08/08/01 601.00 Yes
227 Vehicle Control Ruffled Fur 06/11/2003 08/08/01 673.00 No
227 Vehicle Control Ruffled Fur 07/09/2003 08/08/01 701.00 No
227 Vehicle Control Ruffled Fur 08/04/2003 08/08/01 727.00 Yes
227 Vehicle Control Thin 08/04/2003 08/08/01 727.00 Yes
239 Vehicle Control Thin 10/30/2002 08/08/01 449.00 No
239 Vehicle Control Thin 10/31/2002 08/08/01 450.00 Yes
250 Vehicle Control Eye Abnormality 04/16/2003 08/08/01 617.00 No
250 Vehicle Control Eye Abnormality 05/14/2003 08/08/01 645.00 No
250 Vehicle Control Eye Abnormality 06/11/2003 08/08/01 673.00 No
250 Vehicle Control Eye Abnormality 07/09/2003 08/08/01 701.00 No
250 Vehicle Control Eye Abnormality 08/05/2003 08/08/01 728.00 Yes
257 188 MG/KG Mass Torso/Lateral, Small (1mm-5mm) 1 08/06/2003 08/08/01 729.00 Yes
258 188 MG/KG Mass Torso/Dorsal, Large (16mm And Larger) 1 05/14/2003 08/08/01 645.00 No
258 188 MG/KG Mass Torso/Lateral, Large (16mm And Larger) 1 06/09/2003 08/08/01 671.00 Yes
258 188 MG/KG Thin 06/09/2003 08/08/01 671.00 Yes
258 188 MG/KG Lethargic 06/09/2003 08/08/01 671.00 Yes
260 188 MG/KG Mass Appendage, Large (16mm And Larger) 1 02/07/2003 08/08/01 549.00 Yes
260 188 MG/KG Ulcer/Abscess Appendage 1 02/07/2003 08/08/01 549.00 Yes
264 188 MG/KG Mass Torso/Dorsal, Medium (6mm-15mm) 1 06/11/2003 08/08/01 673.00 No
264 188 MG/KG Mass Torso/Dorsal, Large (16mm And Larger) 1 07/09/2003 08/08/01 701.00 No
264 188 MG/KG Ulcer/Abscess Torso/Dorsal 1 07/09/2003 08/08/01 701.00 No
264 188 MG/KG Mass Torso/Dorsal, Large (16mm And Larger) 1 07/11/2003 08/08/01 703.00 Yes
264 188 MG/KG Ulcer/Abscess Torso/Dorsal 1 07/11/2003 08/08/01 703.00 Yes
266 188 MG/KG Hindlimb Splay 01/16/2003 08/08/01 527.00 Yes
266 188 MG/KG Thin 01/16/2003 08/08/01 527.00 Yes
267 188 MG/KG Abnormal Breathing 04/02/2003 08/08/01 603.00 Yes
274 188 MG/KG Ulcer/Abscess Torso/Ventral 1 01/23/2002 08/08/01 169.00 No
303 375 MG/KG Mass Appendage, Large (16mm And Larger) 1 05/14/2003 08/08/01 645.00 No
303 375 MG/KG Mass Appendage, Large (16mm And Larger) 1 05/17/2003 08/08/01 648.00 Yes
305 375 MG/KG Mass Torso/Dorsal, Medium (6mm-15mm) 1 07/09/2003 08/08/01 701.00 No
305 375 MG/KG Thin 07/09/2003 08/08/01 701.00 Yes
305 375 MG/KG Mass Torso/Dorsal, Medium (6mm-15mm) 1 07/09/2003 08/08/01 701.00 Yes
305 375 MG/KG Thin 07/09/2003 08/08/01 701.00 No
306 375 MG/KG Eye Abnormality 01/22/2003 08/08/01 533.00 No
306 375 MG/KG Eye Abnormality 02/13/2003 08/08/01 555.00 Yes
306 375 MG/KG Mass Head, Small (1mm-5mm) 1 02/13/2003 08/08/01 555.00 Yes
313 375 MG/KG Mass Torso/Lateral, Large (16mm And Larger) 1 07/09/2003 08/08/01 701.00 No
313 375 MG/KG Mass Torso/Lateral, Large (16mm And Larger) 1 08/04/2003 08/08/01 727.00 Yes
314 375 MG/KG Ruffled Fur 06/11/2003 08/08/01 673.00 Yes
314 375 MG/KG Thin 06/11/2003 08/08/01 673.00 Yes
314 375 MG/KG Abnormal Breathing 06/11/2003 08/08/01 673.00 Yes
314 375 MG/KG Lethargic 06/11/2003 08/08/01 673.00 Yes
331 375 MG/KG Eye Abnormality 12/25/2002 08/08/01 505.00 No
331 375 MG/KG Nasal/Eye Discharge 01/22/2003 08/08/01 533.00 No
331 375 MG/KG Eye Abnormality 01/22/2003 08/08/01 533.00 No
331 375 MG/KG Eye Abnormality 02/19/2003 08/08/01 561.00 No
331 375 MG/KG Eye Abnormality 03/19/2003 08/08/01 589.00 No
331 375 MG/KG Eye Abnormality 04/16/2003 08/08/01 617.00 No
331 375 MG/KG Mass Head, Small (1mm-5mm) 1 04/16/2003 08/08/01 617.00 No
331 375 MG/KG Eye Abnormality 05/14/2003 08/08/01 645.00 No
331 375 MG/KG Mass Head, Small (1mm-5mm) 1 05/14/2003 08/08/01 645.00 No
331 375 MG/KG Hindlimb Splay 06/11/2003 08/08/01 673.00 Yes
331 375 MG/KG Ataxia 06/11/2003 08/08/01 673.00 Yes
331 375 MG/KG Mass Head, Small (1mm-5mm) 1 06/11/2003 08/08/01 673.00 Yes
331 375 MG/KG Lethargic 06/11/2003 08/08/01 673.00 Yes
334 375 MG/KG Thin 06/13/2003 08/08/01 675.00 Yes
335 375 MG/KG Thin 04/16/2003 08/08/01 617.00 No
335 375 MG/KG Thin 05/14/2003 08/08/01 645.00 No
335 375 MG/KG Thin 07/09/2003 08/08/01 701.00 No
342 375 MG/KG Thin 04/16/2003 08/08/01 617.00 No
342 375 MG/KG Lethargic 04/25/2003 08/08/01 626.00 Yes
342 375 MG/KG Head Tilt 04/25/2003 08/08/01 626.00 Yes
342 375 MG/KG Ataxia 04/25/2003 08/08/01 626.00 Yes
342 375 MG/KG Thin 04/25/2003 08/08/01 626.00 Yes
343 375 MG/KG Paralysis 07/29/2003 08/08/01 721.00 Yes
349 375 MG/KG Head Tilt 04/14/2003 08/08/01 615.00 Yes
349 375 MG/KG Ataxia 04/14/2003 08/08/01 615.00 Yes
354 750 MG/KG Lethargic 10/08/2002 08/08/01 427.00 Yes
354 750 MG/KG Abnormal Breathing 10/08/2002 08/08/01 427.00 Yes
354 750 MG/KG Ruffled Fur 10/08/2002 08/08/01 427.00 Yes
357 750 MG/KG Eye Abnormality 03/19/2003 08/08/01 589.00 No
357 750 MG/KG Mass Head, Small (1mm-5mm) 1 04/16/2003 08/08/01 617.00 No
357 750 MG/KG Eye Abnormality 04/16/2003 08/08/01 617.00 No
357 750 MG/KG Mass Head, Small (1mm-5mm) 1 05/14/2003 08/08/01 645.00 No
357 750 MG/KG Eye Abnormality 05/14/2003 08/08/01 645.00 No
357 750 MG/KG Eye Abnormality 06/11/2003 08/08/01 673.00 No
357 750 MG/KG Mass Head, Small (1mm-5mm) 1 06/11/2003 08/08/01 673.00 No
357 750 MG/KG Eye Abnormality 06/13/2003 08/08/01 675.00 Yes
357 750 MG/KG Mass Head, Small (1mm-5mm) 1 06/13/2003 08/08/01 675.00 Yes
363 750 MG/KG Thin 07/09/2003 08/08/01 701.00 No
366 750 MG/KG Abnormal Breathing 10/29/2002 08/08/01 448.00 Yes
366 750 MG/KG Lethargic 10/29/2002 08/08/01 448.00 Yes
368 750 MG/KG Thin 06/11/2003 08/08/01 673.00 No
368 750 MG/KG Thin 07/09/2003 08/08/01 701.00 No
375 750 MG/KG Abnormal Breathing 11/18/2002 08/08/01 468.00 Yes
375 750 MG/KG Lethargic 11/18/2002 08/08/01 468.00 Yes
385 750 MG/KG Thin 06/11/2003 08/08/01 673.00 No
385 750 MG/KG Thin 07/09/2003 08/08/01 701.00 No
385 750 MG/KG Ataxia 07/16/2003 08/08/01 708.00 Yes
385 750 MG/KG Thin 07/16/2003 08/08/01 708.00 Yes
385 750 MG/KG Abnormal Breathing 07/16/2003 08/08/01 708.00 Yes
386 750 MG/KG Thin 06/11/2003 08/08/01 673.00 No
386 750 MG/KG Thin 07/09/2003 08/08/01 701.00 No
386 750 MG/KG Thin 08/04/2003 08/08/01 727.00 Yes
388 750 MG/KG Thin 05/28/2003 08/08/01 659.00 Yes
388 750 MG/KG Lethargic 05/28/2003 08/08/01 659.00 Yes