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Short-Term Study Individual Animal Clinical Observations

Study Information:

Chemical Name: Chemical mixture - drinking water contaminants
CASRN: ="CHEMMIXH2O"
Study Number: C62420
Exposure Route: DOSED WATER
TDMS Number: 0519304
Sex: Female
Strain and Species: B6C3F1 Mice

Animal Number Dose Group Clinical Observation Qualifier Incident Number Observation Date First Dose Date Days On Study Removal Observation
151 Vehicle Control Alopecia Body Ventral 01/05/1989 09/27/88 101.00 No
173 Vehicle Control Emaciated 03/16/1989 09/27/88 171.00 No
173 Vehicle Control Emaciated 03/23/1989 09/27/88 178.00 Yes
173 Vehicle Control Abnormal Posture 03/23/1989 09/27/88 178.00 Yes
173 Vehicle Control Abnormal Posture 03/23/1989 09/27/88 178.00 No
173 Vehicle Control Emaciated 03/23/1989 09/27/88 178.00 No
176 Vehicle Control Alopecia Entire Animal 12/15/1988 09/27/88 80.00 No
176 Vehicle Control Alopecia Entire Animal 12/22/1988 09/27/88 87.00 No
176 Vehicle Control Alopecia Entire Animal 12/29/1988 09/27/88 94.00 No
176 Vehicle Control Alopecia Entire Animal 01/05/1989 09/27/88 101.00 No
176 Vehicle Control Alopecia Entire Animal 01/12/1989 09/27/88 108.00 No
176 Vehicle Control Alopecia Entire Animal 01/19/1989 09/27/88 115.00 No
176 Vehicle Control Alopecia Entire Animal 01/26/1989 09/27/88 122.00 No
176 Vehicle Control Alopecia Entire Animal 02/02/1989 09/27/88 129.00 No
176 Vehicle Control Alopecia Entire Animal 02/09/1989 09/27/88 136.00 No
176 Vehicle Control Alopecia Entire Animal 02/16/1989 09/27/88 143.00 No
176 Vehicle Control Alopecia Entire Animal 02/23/1989 09/27/88 150.00 No
176 Vehicle Control Alopecia Entire Animal 03/02/1989 09/27/88 157.00 No
176 Vehicle Control Alopecia Entire Animal 03/09/1989 09/27/88 164.00 No
176 Vehicle Control Alopecia Body Ventral 03/16/1989 09/27/88 171.00 No
176 Vehicle Control Alopecia Body Ventral 03/23/1989 09/27/88 178.00 No
176 Vehicle Control Alopecia Body Ventral 03/23/1989 09/27/88 178.00 Yes
190 25 PPM Alopecia Shoulder 12/29/1988 09/27/88 94.00 No
198 25 PPM Limb Paralysis Right Front Leg 03/28/1989 09/27/88 183.00 Yes
198 25 PPM Swelling Right Front Leg, 0- 2 Mm 03/28/1989 09/27/88 183.00 Yes
204 25 PPM Alopecia Body Dorsal 12/15/1988 09/27/88 80.00 No
204 25 PPM Alopecia Body Dorsal 12/22/1988 09/27/88 87.00 No
207 25 PPM Fractured Appendage Tail 12/15/1988 09/27/88 80.00 No
207 25 PPM Fractured Appendage Tail 12/22/1988 09/27/88 87.00 No
207 25 PPM Fractured Appendage Tail 12/29/1988 09/27/88 94.00 No
207 25 PPM Fractured Appendage Tail 01/05/1989 09/27/88 101.00 No
207 25 PPM Fractured Appendage Tail 01/12/1989 09/27/88 108.00 No
207 25 PPM Fractured Appendage Tail 01/19/1989 09/27/88 115.00 No
207 25 PPM Fractured Appendage Tail 01/26/1989 09/27/88 122.00 No
207 25 PPM Fractured Appendage Tail 02/02/1989 09/27/88 129.00 No
207 25 PPM Fractured Appendage Tail 02/09/1989 09/27/88 136.00 No
207 25 PPM Fractured Appendage Tail 02/16/1989 09/27/88 143.00 No
207 25 PPM Fractured Appendage Tail 02/23/1989 09/27/88 150.00 No
207 25 PPM Fractured Appendage Tail 03/02/1989 09/27/88 157.00 No
207 25 PPM Fractured Appendage Tail 03/09/1989 09/27/88 164.00 No
207 25 PPM Fractured Appendage Tail 03/16/1989 09/27/88 171.00 No
207 25 PPM Fractured Appendage Tail 03/23/1989 09/27/88 178.00 Yes
207 25 PPM Fractured Appendage Tail 03/23/1989 09/27/88 178.00 No
215 75 PPM Fractured Appendage Tail 09/27/1988 09/27/88 1.00 No
215 75 PPM Fractured Appendage Tail 10/01/1988 09/27/88 5.00 No
215 75 PPM Missing Anatomy Tail, 0- 2 Mm 10/07/1988 09/27/88 11.00 No
215 75 PPM Missing Anatomy Tail, 0- 2 Mm 10/14/1988 09/27/88 18.00 No
215 75 PPM Missing Anatomy Tail, 0- 2 Mm 10/20/1988 09/27/88 24.00 No
215 75 PPM Missing Anatomy Tail, 0- 2 Mm 10/27/1988 09/27/88 31.00 No
215 75 PPM Missing Anatomy Tail, 0- 2 Mm 11/03/1988 09/27/88 38.00 No
215 75 PPM Missing Anatomy Tail, 0- 2 Mm 11/10/1988 09/27/88 45.00 No
215 75 PPM Missing Anatomy Tail, 0- 2 Mm 11/17/1988 09/27/88 52.00 No
215 75 PPM Missing Anatomy Tail, 0- 2 Mm 11/24/1988 09/27/88 59.00 No
215 75 PPM Missing Anatomy Tail, 0- 2 Mm 12/01/1988 09/27/88 66.00 No
215 75 PPM Missing Anatomy Tail, 0- 2 Mm 12/08/1988 09/27/88 73.00 No
215 75 PPM Missing Anatomy Tail, 0- 2 Mm 12/15/1988 09/27/88 80.00 No
215 75 PPM Missing Anatomy Tail, 0- 2 Mm 12/22/1988 09/27/88 87.00 No
215 75 PPM Missing Anatomy Tail, 0- 2 Mm 12/29/1988 09/27/88 94.00 No
215 75 PPM Missing Anatomy Tail, 0- 2 Mm 12/30/1988 09/27/88 95.00 Yes
215 75 PPM Fractured Appendage Tail 12/30/1988 09/27/88 95.00 Yes
230 75 PPM Missing Anatomy Tail, 0- 2 Mm 11/17/1988 09/27/88 52.00 No
230 75 PPM Missing Anatomy Tail, 0- 2 Mm 11/24/1988 09/27/88 59.00 No
230 75 PPM Missing Anatomy Tail, 0- 2 Mm 12/01/1988 09/27/88 66.00 No
230 75 PPM Missing Anatomy Tail, 0- 2 Mm 12/09/1988 09/27/88 74.00 No
230 75 PPM Missing Anatomy Tail, 0- 2 Mm 12/15/1988 09/27/88 80.00 No
230 75 PPM Missing Anatomy Tail, 0- 2 Mm 12/22/1988 09/27/88 87.00 No
230 75 PPM Missing Anatomy Tail, 0- 2 Mm 12/29/1988 09/27/88 94.00 No
230 75 PPM Missing Anatomy Tail, 0- 2 Mm 01/05/1989 09/27/88 101.00 No
230 75 PPM Missing Anatomy Tail, 0- 2 Mm 01/12/1989 09/27/88 108.00 No
230 75 PPM Missing Anatomy Tail, 0- 2 Mm 01/19/1989 09/27/88 115.00 No
230 75 PPM Missing Anatomy Tail, 0- 2 Mm 01/26/1989 09/27/88 122.00 No
230 75 PPM Missing Anatomy Tail, 0- 2 Mm 02/02/1989 09/27/88 129.00 No
230 75 PPM Missing Anatomy Tail, 0- 2 Mm 02/09/1989 09/27/88 136.00 No
230 75 PPM Missing Anatomy Tail, 0- 2 Mm 02/16/1989 09/27/88 143.00 No
230 75 PPM Missing Anatomy Tail, 0- 2 Mm 02/23/1989 09/27/88 150.00 No
230 75 PPM Missing Anatomy Tail, 0- 2 Mm 03/02/1989 09/27/88 157.00 No
230 75 PPM Missing Anatomy Tail, 0- 2 Mm 03/09/1989 09/27/88 164.00 No
230 75 PPM Missing Anatomy Tail, 0- 2 Mm 03/16/1989 09/27/88 171.00 No
230 75 PPM Missing Anatomy Tail, 0- 2 Mm 03/23/1989 09/27/88 178.00 No
230 75 PPM Missing Anatomy Tail, 0- 2 Mm 03/28/1989 09/27/88 183.00 Yes
236 75 PPM Alopecia Body Ventral 01/19/1989 09/27/88 115.00 No
236 75 PPM Alopecia Face 03/16/1989 09/27/88 171.00 No
236 75 PPM Alopecia Body Ventral 03/23/1989 09/27/88 178.00 No
236 75 PPM Alopecia Body Ventral 03/23/1989 09/27/88 178.00 Yes
257 224 PPM Fractured Appendage Tail 12/15/1988 09/27/88 80.00 No
257 224 PPM Fractured Appendage Tail 12/22/1988 09/27/88 87.00 No
257 224 PPM Fractured Appendage Tail 12/29/1988 09/27/88 94.00 No
257 224 PPM Fractured Appendage Tail 01/06/1989 09/27/88 102.00 No
257 224 PPM Fractured Appendage Tail 01/12/1989 09/27/88 108.00 No
257 224 PPM Fractured Appendage Tail 01/19/1989 09/27/88 115.00 No
257 224 PPM Fractured Appendage Tail 01/26/1989 09/27/88 122.00 No
257 224 PPM Fractured Appendage Tail 02/02/1989 09/27/88 129.00 No
257 224 PPM Fractured Appendage Tail 02/09/1989 09/27/88 136.00 No
257 224 PPM Fractured Appendage Tail 02/16/1989 09/27/88 143.00 No
257 224 PPM Fractured Appendage Tail 02/23/1989 09/27/88 150.00 No
257 224 PPM Fractured Appendage Tail 03/02/1989 09/27/88 157.00 No
257 224 PPM Fractured Appendage Tail 03/09/1989 09/27/88 164.00 No
257 224 PPM Fractured Appendage Tail 03/16/1989 09/27/88 171.00 No
257 224 PPM Fractured Appendage Tail 03/23/1989 09/27/88 178.00 No
257 224 PPM Fractured Appendage Tail 03/28/1989 09/27/88 183.00 Yes
275 748 PPM Alopecia Entire Animal 12/22/1988 09/27/88 87.00 No
275 748 PPM Alopecia Entire Animal 12/29/1988 09/27/88 94.00 No
275 748 PPM Alopecia Entire Animal 12/30/1988 09/27/88 95.00 Yes