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Current Search Critera

Short-Term Study Individual Animal Clinical Observations

Study Information:

Chemical Name: Diethanolamine
CASRN: ="111-42-2"
Study Number: C55174B
Exposure Route: DERMAL,SOLUTION
TDMS Number: 0516206
Sex: Female
Strain and Species: B6C3F1 Mice

Animal Number Dose Group Clinical Observation Qualifier Incident Number Observation Date First Dose Date Days On Study Removal Observation
67 Vehicle Control Sore Tail 11/16/1987 10/13/87 35.00 No
67 Vehicle Control Sore Tail 11/23/1987 10/13/87 42.00 No
67 Vehicle Control Sore Tail 11/30/1987 10/13/87 49.00 No
101 630 MG/KG Irritation 10/21/1987 10/13/87 9.00 No
101 630 MG/KG Discoloration Hair, White 11/30/1987 10/13/87 49.00 No
101 630 MG/KG Alopecia Body Ventral 12/14/1987 10/13/87 63.00 No
101 630 MG/KG Alopecia Body Ventral 12/21/1987 10/13/87 70.00 No
101 630 MG/KG Alopecia Body Ventral 12/28/1987 10/13/87 77.00 No
101 630 MG/KG Alopecia Body Ventral 01/04/1988 10/13/87 84.00 No
101 630 MG/KG Alopecia Body Ventral 01/11/1988 10/13/87 91.00 No
101 630 MG/KG Alopecia Body Ventral 01/15/1988 10/13/87 95.00 Yes
102 630 MG/KG Irritation 10/21/1987 10/13/87 9.00 No
103 630 MG/KG (Skin Paint Only) Crusty 01/11/1988 10/13/87 91.00 No
104 630 MG/KG Irritation 10/21/1987 10/13/87 9.00 No
104 630 MG/KG Discoloration Hair, White 11/23/1987 10/13/87 42.00 No
104 630 MG/KG Irritation 11/23/1987 10/13/87 42.00 No
104 630 MG/KG Discoloration Hair, White 12/21/1987 10/13/87 70.00 No
104 630 MG/KG Discoloration Hair, White 01/04/1988 10/13/87 84.00 No
105 630 MG/KG Irritation 10/21/1987 10/13/87 9.00 No
105 630 MG/KG Irritation 11/23/1987 10/13/87 42.00 No
105 630 MG/KG Emaciated 01/15/1988 10/13/87 95.00 Yes
106 630 MG/KG Discoloration Hair, White 11/30/1987 10/13/87 49.00 No
106 630 MG/KG Discoloration Hair, White 01/11/1988 10/13/87 91.00 No
107 630 MG/KG (Skin Paint Only) Discoloration Yellow 10/28/1987 10/13/87 16.00 No
107 630 MG/KG Alopecia Body Ventral 01/11/1988 10/13/87 91.00 No
107 630 MG/KG Alopecia Body Ventral 01/15/1988 10/13/87 95.00 Yes
108 630 MG/KG Irritation 10/28/1987 10/13/87 16.00 No
108 630 MG/KG Irritation 11/02/1987 10/13/87 21.00 No
108 630 MG/KG Irritation 11/09/1987 10/13/87 28.00 No
108 630 MG/KG Discoloration Hair, White 11/30/1987 10/13/87 49.00 No
108 630 MG/KG Discoloration Hair, White 12/21/1987 10/13/87 70.00 No
109 630 MG/KG Irritation 10/28/1987 10/13/87 16.00 No
109 630 MG/KG Irritation 11/02/1987 10/13/87 21.00 No
109 630 MG/KG Irritation 11/09/1987 10/13/87 28.00 No
109 630 MG/KG (Skin Paint Only) Discoloration White 11/09/1987 10/13/87 28.00 No
109 630 MG/KG Discoloration Hair, White 11/16/1987 10/13/87 35.00 No
109 630 MG/KG Discoloration Hair, White 11/30/1987 10/13/87 49.00 No
109 630 MG/KG Discoloration Hair, White 12/07/1987 10/13/87 56.00 No
109 630 MG/KG Discoloration Hair, White 01/04/1988 10/13/87 84.00 No
109 630 MG/KG Discoloration Hair, White 01/11/1988 10/13/87 91.00 No
110 630 MG/KG Discoloration Hair, White 01/04/1988 10/13/87 84.00 No
111 1250 MG/KG Irritation 10/14/1987 10/13/87 2.00 No
111 1250 MG/KG Irritation 10/21/1987 10/13/87 9.00 No
111 1250 MG/KG (Skin Paint Only) Crusty 10/21/1987 10/13/87 9.00 No
111 1250 MG/KG (Skin Paint Only) Crusty 10/28/1987 10/13/87 16.00 No
111 1250 MG/KG (Skin Paint Only) Crusty 11/02/1987 10/13/87 21.00 No
111 1250 MG/KG (Skin Paint Only) Discoloration White 11/09/1987 10/13/87 28.00 No
111 1250 MG/KG (Skin Paint Only) Crusty 11/09/1987 10/13/87 28.00 No
111 1250 MG/KG (Skin Paint Only) Crusty 11/16/1987 10/13/87 35.00 No
111 1250 MG/KG Discoloration Hair, White 11/16/1987 10/13/87 35.00 No
111 1250 MG/KG (Skin Paint Only) Crusty 11/23/1987 10/13/87 42.00 No
111 1250 MG/KG Discoloration Hair, White 11/23/1987 10/13/87 42.00 No
111 1250 MG/KG (Skin Paint Only) Crusty 11/30/1987 10/13/87 49.00 No
111 1250 MG/KG Discoloration Hair, White 11/30/1987 10/13/87 49.00 No
111 1250 MG/KG (Skin Paint Only) Crusty 12/07/1987 10/13/87 56.00 No
111 1250 MG/KG Discoloration Hair, White 12/07/1987 10/13/87 56.00 No
111 1250 MG/KG (Skin Paint Only) Crusty 12/14/1987 10/13/87 63.00 No
111 1250 MG/KG Discoloration Hair, White 12/14/1987 10/13/87 63.00 No
111 1250 MG/KG (Skin Paint Only) Crusty 12/21/1987 10/13/87 70.00 No
111 1250 MG/KG Discoloration Hair, White 12/21/1987 10/13/87 70.00 No
111 1250 MG/KG (Skin Paint Only) Crusty 12/28/1987 10/13/87 77.00 No
111 1250 MG/KG Discoloration Hair, White 12/28/1987 10/13/87 77.00 No
111 1250 MG/KG Discoloration Hair, White 01/04/1988 10/13/87 84.00 No
111 1250 MG/KG (Skin Paint Only) Crusty 01/04/1988 10/13/87 84.00 No
111 1250 MG/KG Discoloration Hair, White 01/11/1988 10/13/87 91.00 No
111 1250 MG/KG (Skin Paint Only) Crusty 01/11/1988 10/13/87 91.00 No
111 1250 MG/KG (Skin Paint Only) Crusty 01/15/1988 10/13/87 95.00 Yes
111 1250 MG/KG Discoloration Hair, White 01/15/1988 10/13/87 95.00 Yes
112 1250 MG/KG Irritation 10/14/1987 10/13/87 2.00 No
112 1250 MG/KG (Skin Paint Only) Crusty 10/21/1987 10/13/87 9.00 No
112 1250 MG/KG Irritation 10/21/1987 10/13/87 9.00 No
112 1250 MG/KG (Skin Paint Only) Crusty 10/28/1987 10/13/87 16.00 No
112 1250 MG/KG (Skin Paint Only) Crusty 11/02/1987 10/13/87 21.00 No
112 1250 MG/KG (Skin Paint Only) Crusty 11/09/1987 10/13/87 28.00 No
112 1250 MG/KG (Skin Paint Only) Crusty 11/16/1987 10/13/87 35.00 No
112 1250 MG/KG Discoloration Hair, White 11/16/1987 10/13/87 35.00 No
112 1250 MG/KG Discoloration Hair, White 11/23/1987 10/13/87 42.00 No
112 1250 MG/KG (Skin Paint Only) Crusty 11/23/1987 10/13/87 42.00 No
112 1250 MG/KG (Skin Paint Only) Crusty 11/30/1987 10/13/87 49.00 No
112 1250 MG/KG (Skin Paint Only) Crusty 12/07/1987 10/13/87 56.00 No
112 1250 MG/KG (Skin Paint Only) Crusty 12/14/1987 10/13/87 63.00 No
112 1250 MG/KG (Skin Paint Only) Crusty 12/21/1987 10/13/87 70.00 No
112 1250 MG/KG Discoloration Hair, White 12/28/1987 10/13/87 77.00 No
112 1250 MG/KG (Skin Paint Only) Crusty 01/04/1988 10/13/87 84.00 No
112 1250 MG/KG (Skin Paint Only) Crusty 01/11/1988 10/13/87 91.00 No
112 1250 MG/KG (Skin Paint Only) Crusty 01/15/1988 10/13/87 95.00 Yes
112 1250 MG/KG Discoloration Hair, White 01/15/1988 10/13/87 95.00 Yes
113 1250 MG/KG Irritation 10/14/1987 10/13/87 2.00 No
113 1250 MG/KG Thickened 10/21/1987 10/13/87 9.00 No
113 1250 MG/KG Irritation 10/21/1987 10/13/87 9.00 No
113 1250 MG/KG (Skin Paint Only) Crusty 10/28/1987 10/13/87 16.00 No
113 1250 MG/KG (Skin Paint Only) Crusty 11/02/1987 10/13/87 21.00 No
113 1250 MG/KG (Skin Paint Only) Crusty 11/09/1987 10/13/87 28.00 No
113 1250 MG/KG Sore Right Ear 11/16/1987 10/13/87 35.00 No
113 1250 MG/KG (Skin Paint Only) Crusty 11/16/1987 10/13/87 35.00 No
113 1250 MG/KG (Skin Paint Only) Crusty 11/23/1987 10/13/87 42.00 No
113 1250 MG/KG (Skin Paint Only) Crusty 11/30/1987 10/13/87 49.00 No
113 1250 MG/KG (Skin Paint Only) Crusty 12/07/1987 10/13/87 56.00 No
113 1250 MG/KG (Skin Paint Only) Crusty 12/14/1987 10/13/87 63.00 No
113 1250 MG/KG (Skin Paint Only) Crusty 12/21/1987 10/13/87 70.00 No
113 1250 MG/KG (Skin Paint Only) Crusty 12/28/1987 10/13/87 77.00 No
113 1250 MG/KG Discoloration Hair, White 12/28/1987 10/13/87 77.00 No
113 1250 MG/KG (Skin Paint Only) Crusty 01/04/1988 10/13/87 84.00 No
113 1250 MG/KG (Skin Paint Only) Crusty 01/11/1988 10/13/87 91.00 No
113 1250 MG/KG (Skin Paint Only) Crusty 01/15/1988 10/13/87 95.00 Yes
114 1250 MG/KG Irritation 10/21/1987 10/13/87 9.00 No
114 1250 MG/KG Thickened 10/21/1987 10/13/87 9.00 No
114 1250 MG/KG (Skin Paint Only) Crusty 10/28/1987 10/13/87 16.00 No
114 1250 MG/KG Prostration 11/02/1987 10/13/87 21.00 Yes
114 1250 MG/KG Emaciated 11/02/1987 10/13/87 21.00 Yes
114 1250 MG/KG (Skin Paint Only) Crusty 11/02/1987 10/13/87 21.00 Yes
115 1250 MG/KG (Skin Paint Only) Crusty 10/14/1987 10/13/87 2.00 No
115 1250 MG/KG Irritation 10/14/1987 10/13/87 2.00 No
115 1250 MG/KG Irritation 10/21/1987 10/13/87 9.00 No
115 1250 MG/KG (Skin Paint Only) Crusty 10/21/1987 10/13/87 9.00 No
115 1250 MG/KG Irritation 10/28/1987 10/13/87 16.00 No
116 1250 MG/KG Thickened 10/21/1987 10/13/87 9.00 No
116 1250 MG/KG (Skin Paint Only) Crusty 10/28/1987 10/13/87 16.00 No
116 1250 MG/KG (Skin Paint Only) Crusty 11/02/1987 10/13/87 21.00 No
116 1250 MG/KG (Skin Paint Only) Crusty 11/09/1987 10/13/87 28.00 No
116 1250 MG/KG (Skin Paint Only) Discoloration White 11/09/1987 10/13/87 28.00 No
116 1250 MG/KG (Skin Paint Only) Crusty 11/16/1987 10/13/87 35.00 No
116 1250 MG/KG Discoloration Hair, White 11/16/1987 10/13/87 35.00 No
116 1250 MG/KG Discoloration Hair, White 11/23/1987 10/13/87 42.00 No
116 1250 MG/KG (Skin Paint Only) Crusty 11/23/1987 10/13/87 42.00 No
116 1250 MG/KG (Skin Paint Only) Crusty 11/30/1987 10/13/87 49.00 No
116 1250 MG/KG Discoloration Hair, White 11/30/1987 10/13/87 49.00 No
116 1250 MG/KG Irritation 12/07/1987 10/13/87 56.00 No
116 1250 MG/KG Discoloration Hair, White 12/07/1987 10/13/87 56.00 No
116 1250 MG/KG (Skin Paint Only) Crusty 12/14/1987 10/13/87 63.00 No
116 1250 MG/KG (Skin Paint Only) Crusty 12/21/1987 10/13/87 70.00 No
116 1250 MG/KG (Skin Paint Only) Crusty 12/28/1987 10/13/87 77.00 No
116 1250 MG/KG Discoloration Hair, White 12/28/1987 10/13/87 77.00 No
116 1250 MG/KG (Skin Paint Only) Crusty 01/04/1988 10/13/87 84.00 No
116 1250 MG/KG Discoloration Hair, White 01/04/1988 10/13/87 84.00 No
116 1250 MG/KG (Skin Paint Only) Crusty 01/11/1988 10/13/87 91.00 No
116 1250 MG/KG Discoloration Hair, White 01/11/1988 10/13/87 91.00 No
116 1250 MG/KG Discoloration Hair, White 01/15/1988 10/13/87 95.00 Yes
116 1250 MG/KG (Skin Paint Only) Crusty 01/15/1988 10/13/87 95.00 Yes
117 1250 MG/KG (Skin Paint Only) Crusty 10/21/1987 10/13/87 9.00 No
117 1250 MG/KG Thickened 10/21/1987 10/13/87 9.00 No
117 1250 MG/KG Irritation 10/21/1987 10/13/87 9.00 No
117 1250 MG/KG (Skin Paint Only) Crusty 10/24/1987 10/13/87 12.00 Yes
117 1250 MG/KG Thickened 10/24/1987 10/13/87 12.00 Yes
117 1250 MG/KG Irritation 10/24/1987 10/13/87 12.00 Yes
118 1250 MG/KG Thickened 10/21/1987 10/13/87 9.00 No
118 1250 MG/KG (Skin Paint Only) Scaly 10/21/1987 10/13/87 9.00 No
118 1250 MG/KG Thickened 10/24/1987 10/13/87 12.00 Yes
118 1250 MG/KG (Skin Paint Only) Scaly 10/24/1987 10/13/87 12.00 Yes
119 1250 MG/KG (Skin Paint Only) Discoloration Red 10/14/1987 10/13/87 2.00 No
119 1250 MG/KG (Skin Paint Only) Scaly 10/21/1987 10/13/87 9.00 No
119 1250 MG/KG Irritation 10/21/1987 10/13/87 9.00 No
119 1250 MG/KG Thickened 10/21/1987 10/13/87 9.00 No
119 1250 MG/KG (Skin Paint Only) Crusty 10/21/1987 10/13/87 9.00 No
119 1250 MG/KG (Skin Paint Only) Crusty 10/28/1987 10/13/87 16.00 No
119 1250 MG/KG (Skin Paint Only) Crusty 11/02/1987 10/13/87 21.00 No
119 1250 MG/KG (Skin Paint Only) Crusty 11/09/1987 10/13/87 28.00 No
119 1250 MG/KG (Skin Paint Only) Crusty 11/16/1987 10/13/87 35.00 No
119 1250 MG/KG (Skin Paint Only) Crusty 11/23/1987 10/13/87 42.00 No
119 1250 MG/KG Discoloration Hair, White 11/30/1987 10/13/87 49.00 No
119 1250 MG/KG Sore Right Ear 11/30/1987 10/13/87 49.00 No
119 1250 MG/KG (Skin Paint Only) Crusty 11/30/1987 10/13/87 49.00 No
119 1250 MG/KG Discoloration Hair, White 12/07/1987 10/13/87 56.00 No
119 1250 MG/KG Sore Right Ear 12/07/1987 10/13/87 56.00 No
119 1250 MG/KG (Skin Paint Only) Crusty 12/07/1987 10/13/87 56.00 No
119 1250 MG/KG (Skin Paint Only) Crusty 12/14/1987 10/13/87 63.00 No
119 1250 MG/KG Discoloration Hair, White 12/21/1987 10/13/87 70.00 No
119 1250 MG/KG (Skin Paint Only) Crusty 12/21/1987 10/13/87 70.00 No
119 1250 MG/KG Discoloration Hair, White 12/28/1987 10/13/87 77.00 No
119 1250 MG/KG Missing Anatomy Right Ear, 0- 2 Mm 12/28/1987 10/13/87 77.00 No
119 1250 MG/KG Missing Anatomy Right Ear, 0- 2 Mm 01/04/1988 10/13/87 84.00 No
119 1250 MG/KG (Skin Paint Only) Crusty 01/04/1988 10/13/87 84.00 No
119 1250 MG/KG Discoloration Hair, White 01/11/1988 10/13/87 91.00 No
119 1250 MG/KG Missing Anatomy Right Ear, 0- 2 Mm 01/11/1988 10/13/87 91.00 No
119 1250 MG/KG (Skin Paint Only) Crusty 01/11/1988 10/13/87 91.00 No
119 1250 MG/KG (Skin Paint Only) Crusty 01/15/1988 10/13/87 95.00 Yes
119 1250 MG/KG Discoloration Hair, White 01/15/1988 10/13/87 95.00 Yes
119 1250 MG/KG Missing Anatomy Right Ear, 0- 2 Mm 01/15/1988 10/13/87 95.00 Yes
120 1250 MG/KG Irritation 10/14/1987 10/13/87 2.00 No
120 1250 MG/KG (Skin Paint Only) Crusty 10/14/1987 10/13/87 2.00 No
120 1250 MG/KG (Skin Paint Only) Crusty 10/21/1987 10/13/87 9.00 No
120 1250 MG/KG (Skin Paint Only) Crusty 10/28/1987 10/13/87 16.00 No
120 1250 MG/KG (Skin Paint Only) Crusty 11/02/1987 10/13/87 21.00 No
120 1250 MG/KG (Skin Paint Only) Crusty 11/09/1987 10/13/87 28.00 No
120 1250 MG/KG (Skin Paint Only) Crusty 11/16/1987 10/13/87 35.00 No
120 1250 MG/KG (Skin Paint Only) Crusty 11/23/1987 10/13/87 42.00 No
120 1250 MG/KG (Skin Paint Only) Crusty 11/30/1987 10/13/87 49.00 No
120 1250 MG/KG (Skin Paint Only) Crusty 12/07/1987 10/13/87 56.00 No
120 1250 MG/KG Discoloration Hair, White 12/07/1987 10/13/87 56.00 No
120 1250 MG/KG (Skin Paint Only) Crusty 12/14/1987 10/13/87 63.00 No
120 1250 MG/KG (Skin Paint Only) Crusty 12/21/1987 10/13/87 70.00 No
120 1250 MG/KG Discoloration Hair, White 12/28/1987 10/13/87 77.00 No
120 1250 MG/KG (Skin Paint Only) Crusty 01/04/1988 10/13/87 84.00 No
120 1250 MG/KG (Skin Paint Only) Crusty 01/11/1988 10/13/87 91.00 No
120 1250 MG/KG Discoloration Hair, White 01/11/1988 10/13/87 91.00 No
120 1250 MG/KG (Skin Paint Only) Crusty 01/15/1988 10/13/87 95.00 Yes