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Current Search Critera

Long-Term Study Individual Animal Clinical Observations

Study Information:

Chemical Name: Dipropylene glycol
CASRN: ="25265-71-8"
Study Number: C88031B
Exposure Route: DOSED WATER
TDMS Number: 8803106
Sex: Female
Strain and Species: B6C3F1 Mice

Animal Number Dose Group Clinical Observation Qualifier Incident Number Observation Date First Dose Date Days On Study Removal Observation
204 Vehicle Control Mass Torso/Dorsal, Large (16mm And Larger) 1 12/18/1998 03/18/97 641.00 Yes
204 Vehicle Control Paralysis 12/18/1998 03/18/97 641.00 Yes
212 Vehicle Control Lethargic 01/26/1999 03/18/97 680.00 No
212 Vehicle Control Thin 01/26/1999 03/18/97 680.00 No
212 Vehicle Control Thin 01/29/1999 03/18/97 683.00 Yes
227 Vehicle Control Eye Abnormality 12/29/1998 03/18/97 652.00 No
227 Vehicle Control Eye Abnormality 01/26/1999 03/18/97 680.00 No
227 Vehicle Control Eye Abnormality 02/23/1999 03/18/97 708.00 No
227 Vehicle Control Mass Head, Small (1mm-5mm) 1 02/23/1999 03/18/97 708.00 No
227 Vehicle Control Eye Abnormality 03/17/1999 03/18/97 730.00 Yes
227 Vehicle Control Mass Head, Small (1mm-5mm) 1 03/17/1999 03/18/97 730.00 Yes
236 Vehicle Control Thin 10/06/1998 03/18/97 568.00 No
236 Vehicle Control Mass Head, Large (16mm And Larger) 1 10/06/1998 03/18/97 568.00 No
236 Vehicle Control Thin 10/08/1998 03/18/97 570.00 Yes
236 Vehicle Control Mass Head, Large (16mm And Larger) 1 10/08/1998 03/18/97 570.00 Yes
237 Vehicle Control Mass Torso/Lateral, Medium (6mm-15mm) 1 02/23/1999 03/18/97 708.00 No
237 Vehicle Control Mass Torso/Lateral, Large (16mm And Larger) 1 03/16/1999 03/18/97 729.00 Yes
239 Vehicle Control Thin 07/27/1998 03/18/97 497.00 Yes
239 Vehicle Control Ruffled Fur 07/27/1998 03/18/97 497.00 Yes
243 Vehicle Control Abnormal Breathing 12/01/1998 03/18/97 624.00 No
243 Vehicle Control Head Tilt 12/01/1998 03/18/97 624.00 No
243 Vehicle Control Head Tilt 12/29/1998 03/18/97 652.00 No
243 Vehicle Control Head Tilt 01/26/1999 03/18/97 680.00 No
243 Vehicle Control Thin 01/26/1999 03/18/97 680.00 No
243 Vehicle Control Mass Torso/Ventral, Small (1mm-5mm) 1 01/26/1999 03/18/97 680.00 No
243 Vehicle Control Mass Torso/Ventral, Small (1mm-5mm) 1 02/19/1999 03/18/97 704.00 Yes
243 Vehicle Control Thin 02/19/1999 03/18/97 704.00 Yes
250 Vehicle Control Mass Torso/Lateral, Large (16mm And Larger) 1 03/08/1999 03/18/97 721.00 Yes
252 1.0 % Mass Torso/Ventral, Large (16mm And Larger) 1 02/04/1999 03/18/97 689.00 Yes
253 1.0 % Mass Torso/Lateral, Large (16mm And Larger) 1 12/29/1998 03/18/97 652.00 No
253 1.0 % Mass Torso/Lateral, Large (16mm And Larger) 1 01/26/1999 03/18/97 680.00 No
253 1.0 % Eye Abnormality 02/23/1999 03/18/97 708.00 No
253 1.0 % Eye Abnormality 03/15/1999 03/18/97 728.00 Yes
256 1.0 % Mass Torso/Lateral, Medium (6mm-15mm) 2 01/26/1999 03/18/97 680.00 No
256 1.0 % Mass Torso/Ventral, Large (16mm And Larger) 1 02/02/1999 03/18/97 687.00 Yes
257 1.0 % Mass Torso/Lateral, Medium (6mm-15mm) 1 02/23/1999 03/18/97 708.00 No
257 1.0 % Mass Torso/Lateral, Medium (6mm-15mm) 1 03/16/1999 03/18/97 729.00 Yes
262 1.0 % Mass Torso/Lateral, Medium (6mm-15mm) 1 01/26/1999 03/18/97 680.00 No
262 1.0 % Mass Torso/Lateral, Medium (6mm-15mm) 1 02/23/1999 03/18/97 708.00 No
262 1.0 % Mass Torso/Lateral, Large (16mm And Larger) 2 02/26/1999 03/18/97 711.00 Yes
264 1.0 % Mass Torso/Dorsal, Medium (6mm-15mm) 1 03/15/1999 03/18/97 728.00 Yes
275 1.0 % Mass Torso/Dorsal, Medium (6mm-15mm) 1 01/26/1999 03/18/97 680.00 No
275 1.0 % Mass Torso/Dorsal, Medium (6mm-15mm) 1 02/08/1999 03/18/97 693.00 Yes
283 1.0 % Mass Torso/Ventral, Large (16mm And Larger) 1 03/13/1999 03/18/97 726.00 Yes
285 1.0 % Mass Torso/Ventral, Large (16mm And Larger) 1 12/01/1998 03/18/97 624.00 No
285 1.0 % Mass Torso/Lateral, Medium (6mm-15mm) 1 12/01/1998 03/18/97 624.00 No
285 1.0 % Mass Torso/Ventral, Large (16mm And Larger) 1 12/18/1998 03/18/97 641.00 Yes
289 1.0 % Mass Torso/Ventral, Medium (6mm-15mm) 1 03/16/1999 03/18/97 729.00 Yes
293 1.0 % Thin 09/08/1998 03/18/97 540.00 No
293 1.0 % Thin 09/11/1998 03/18/97 543.00 Yes
299 1.0 % Mass Torso/Lateral, Medium (6mm-15mm) 1 03/16/1999 03/18/97 729.00 Yes
308 2.0 % Abnormal Breathing 12/01/1998 03/18/97 624.00 No
308 2.0 % Thin 12/01/1998 03/18/97 624.00 No
308 2.0 % Thin 12/29/1998 03/18/97 652.00 No
308 2.0 % Abnormal Breathing 12/29/1998 03/18/97 652.00 No
308 2.0 % Abnormal Breathing 12/31/1998 03/18/97 654.00 Yes
308 2.0 % Thin 12/31/1998 03/18/97 654.00 Yes
313 2.0 % Mass Torso/Lateral, Large (16mm And Larger) 1 10/06/1998 03/18/97 568.00 No
320 2.0 % Abnormal Breathing 11/03/1998 03/18/97 596.00 No
327 2.0 % Thin 09/11/1998 03/18/97 543.00 Yes
339 2.0 % Mass Torso/Ventral, Large (16mm And Larger) 2 12/29/1998 03/18/97 652.00 No
339 2.0 % Mass Torso/Ventral, Large (16mm And Larger) 2 12/31/1998 03/18/97 654.00 Yes
341 2.0 % Ulcer/Abscess Torso/Dorsal 1 12/29/1998 03/18/97 652.00 No
341 2.0 % Ulcer/Abscess Torso/Dorsal 1 01/26/1999 03/18/97 680.00 No
341 2.0 % Ulcer/Abscess Torso/Dorsal 3 02/23/1999 03/18/97 708.00 No
341 2.0 % Ulcer/Abscess Torso/Dorsal 5 03/16/1999 03/18/97 729.00 Yes
350 2.0 % Mass Appendage, Large (16mm And Larger) 1 10/06/1998 03/18/97 568.00 No
350 2.0 % Mass Appendage, Large (16mm And Larger) 1 10/14/1998 03/18/97 576.00 Yes
351 4.0 % Abnormal Breathing 07/31/1998 03/18/97 501.00 Yes
351 4.0 % Lethargic 07/31/1998 03/18/97 501.00 Yes
354 4.0 % Abnormal Breathing 07/31/1998 03/18/97 501.00 Yes
354 4.0 % Lethargic 07/31/1998 03/18/97 501.00 Yes
357 4.0 % Mass Torso/Dorsal, Medium (6mm-15mm) 1 01/26/1999 03/18/97 680.00 No
357 4.0 % Mass Torso/Dorsal, Large (16mm And Larger) 1 02/23/1999 03/18/97 708.00 No
357 4.0 % Thin 02/23/1999 03/18/97 708.00 No
357 4.0 % Thin 03/15/1999 03/18/97 728.00 Yes
357 4.0 % Mass Torso/Dorsal, Large (16mm And Larger) 1 03/15/1999 03/18/97 728.00 Yes
364 4.0 % Lethargic 09/10/1998 03/18/97 542.00 Yes
364 4.0 % Abnormal Breathing 09/10/1998 03/18/97 542.00 Yes
367 4.0 % Thin 06/12/1998 03/18/97 452.00 Yes
371 4.0 % Mass Torso/Ventral, Medium (6mm-15mm) 1 03/16/1999 03/18/97 729.00 Yes
373 4.0 % Thin 12/01/1998 03/18/97 624.00 No
373 4.0 % Thin 12/29/1998 03/18/97 652.00 No
373 4.0 % Thin 01/26/1999 03/18/97 680.00 No
373 4.0 % Thin 02/23/1999 03/18/97 708.00 No
373 4.0 % Thin 03/17/1999 03/18/97 730.00 Yes
376 4.0 % Thin 10/31/1997 03/18/97 228.00 Yes
377 4.0 % Abnormal Breathing 12/29/1998 03/18/97 652.00 No
377 4.0 % Thin 12/29/1998 03/18/97 652.00 No
377 4.0 % Abnormal Breathing 12/31/1998 03/18/97 654.00 Yes
377 4.0 % Thin 12/31/1998 03/18/97 654.00 Yes
382 4.0 % Ruffled Fur 12/30/1997 03/18/97 288.00 No
382 4.0 % Mass Torso/Dorsal, Medium (6mm-15mm) 1 01/27/1998 03/18/97 316.00 No
382 4.0 % Ruffled Fur 01/27/1998 03/18/97 316.00 No
382 4.0 % Mass Torso/Dorsal, Medium (6mm-15mm) 1 02/24/1998 03/18/97 344.00 No
382 4.0 % Ruffled Fur 02/24/1998 03/18/97 344.00 No
382 4.0 % Mass Torso/Dorsal, Small (1mm-5mm) 1 03/24/1998 03/18/97 372.00 No
382 4.0 % Ruffled Fur 03/24/1998 03/18/97 372.00 No
382 4.0 % Ruffled Fur 04/16/1998 03/18/97 395.00 Yes
382 4.0 % Thin 04/16/1998 03/18/97 395.00 Yes
383 4.0 % Mass Torso/Lateral, Large (16mm And Larger) 1 02/02/1999 03/18/97 687.00 Yes
385 4.0 % Mass Torso/Dorsal, Medium (6mm-15mm) 1 10/03/1998 03/18/97 565.00 Yes
392 4.0 % Eye Abnormality 02/23/1999 03/18/97 708.00 No
392 4.0 % Eye Abnormality 03/15/1999 03/18/97 728.00 Yes
400 4.0 % Mass Torso/Ventral, Small (1mm-5mm) 1 12/29/1998 03/18/97 652.00 No
400 4.0 % Mass Torso/Ventral, Small (1mm-5mm) 1 01/26/1999 03/18/97 680.00 No
400 4.0 % Mass Torso/Lateral, Medium (6mm-15mm) 1 02/23/1999 03/18/97 708.00 No
400 4.0 % Mass Torso/Lateral, Medium (6mm-15mm) 1 03/15/1999 03/18/97 728.00 Yes