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Current Search Critera

Short-Term Study Individual Animal Clinical Observations

Study Information:

Chemical Name: Isobutyl nitrite
CASRN: ="542-56-3"
Study Number: C61052B
Exposure Route: RESPIRATORY EXPOSURE WHOLE BODY
TDMS Number: 0518501
Sex: Female
Strain and Species: F 344/N Rats

Animal Number Dose Group Clinical Observation Qualifier Incident Number Observation Date First Dose Date Days On Study Removal Observation
11 Vehicle Control Discharge Vaginal Area, Yellow 07/01/1987 04/16/87 77.00 No
34 10 PPM Wound Tail 05/07/1987 04/16/87 22.00 No
34 10 PPM Wound Tail 05/14/1987 04/16/87 29.00 No
38 10 PPM Wound Tail 05/14/1987 04/16/87 29.00 No
38 10 PPM Wound Tail 05/21/1987 04/16/87 36.00 No
38 10 PPM Wound Tail 06/04/1987 04/16/87 50.00 No
40 10 PPM Nasal Discharge Red 05/07/1987 04/16/87 22.00 No
40 10 PPM Discharge Vaginal Area, Yellow 07/01/1987 04/16/87 77.00 No
51 25 PPM Ruffled Fur 04/30/1987 04/16/87 15.00 No
51 25 PPM Discharge Vaginal Area, Yellow 06/18/1987 04/16/87 64.00 No
51 25 PPM Discharge Vaginal Area, Clear 06/25/1987 04/16/87 71.00 No
51 25 PPM Discharge Vaginal Area, Yellow 07/01/1987 04/16/87 77.00 No
54 25 PPM Wound Tail 05/14/1987 04/16/87 29.00 No
56 25 PPM Ruffled Fur 04/30/1987 04/16/87 15.00 No
58 25 PPM Discharge Vaginal Area, Yellow 06/25/1987 04/16/87 71.00 No
59 25 PPM Wound Tail 05/21/1987 04/16/87 36.00 No
60 25 PPM Wound Tail 07/15/1987 04/16/87 91.00 Yes
71 75 PPM Wound Tail 06/04/1987 04/16/87 50.00 No
71 75 PPM Wound Tail 07/09/1987 04/16/87 85.00 No
73 75 PPM Discharge Vaginal Area, Yellow 06/18/1987 04/16/87 64.00 No
76 75 PPM Wound Nose 06/04/1987 04/16/87 50.00 No
76 75 PPM Wound Nose 06/11/1987 04/16/87 57.00 No
77 75 PPM Wound Toes 07/09/1987 04/16/87 85.00 No
100 150 PPM Hyperactive 04/21/1987 04/16/87 6.00 No
100 150 PPM Wound Tail 06/25/1987 04/16/87 71.00 No
111 300 PPM Ruffled Fur 04/30/1987 04/16/87 15.00 No
111 300 PPM Ruffled Fur 05/07/1987 04/16/87 22.00 No
111 300 PPM Ruffled Fur 05/14/1987 04/16/87 29.00 No
111 300 PPM Ruffled Fur 05/21/1987 04/16/87 36.00 No
112 300 PPM Hyperactive 04/22/1987 04/16/87 7.00 No
112 300 PPM Hyperactive 04/23/1987 04/16/87 8.00 No
112 300 PPM Hyperactive 05/07/1987 04/16/87 22.00 No
112 300 PPM Ruffled Fur 05/14/1987 04/16/87 29.00 No
112 300 PPM Ruffled Fur 05/21/1987 04/16/87 36.00 No
112 300 PPM Hyperactive 06/04/1987 04/16/87 50.00 No
112 300 PPM Hyperactive 06/18/1987 04/16/87 64.00 No
112 300 PPM Hyperactive 06/25/1987 04/16/87 71.00 No
113 300 PPM Nasal Discharge Red 04/16/1987 04/16/87 1.00 No
113 300 PPM Hyperactive 04/22/1987 04/16/87 7.00 No
113 300 PPM Hyperactive 04/23/1987 04/16/87 8.00 No
113 300 PPM Ruffled Fur 04/30/1987 04/16/87 15.00 No
113 300 PPM Ruffled Fur 05/07/1987 04/16/87 22.00 No
113 300 PPM Hyperactive 05/07/1987 04/16/87 22.00 No
113 300 PPM Ruffled Fur 05/14/1987 04/16/87 29.00 No
113 300 PPM Ruffled Fur 05/28/1987 04/16/87 43.00 No
113 300 PPM Hyperactive 06/18/1987 04/16/87 64.00 No
113 300 PPM Discharge Vaginal Area, Yellow 06/18/1987 04/16/87 64.00 No
113 300 PPM Discharge Vaginal Area, Yellow 06/25/1987 04/16/87 71.00 No
113 300 PPM Discharge Vaginal Area, Yellow 07/01/1987 04/16/87 77.00 No
114 300 PPM Hyperactive 04/22/1987 04/16/87 7.00 No
115 300 PPM Hyperactive 04/22/1987 04/16/87 7.00 No
115 300 PPM Ruffled Fur 05/07/1987 04/16/87 22.00 No
116 300 PPM Hyperactive 04/22/1987 04/16/87 7.00 No
116 300 PPM Hyperactive 04/23/1987 04/16/87 8.00 No
116 300 PPM Hyperactive 05/07/1987 04/16/87 22.00 No
116 300 PPM Ruffled Fur 06/04/1987 04/16/87 50.00 No
117 300 PPM Hyperactive 04/23/1987 04/16/87 8.00 No
117 300 PPM Hyperactive 05/07/1987 04/16/87 22.00 No
117 300 PPM Ruffled Fur 05/07/1987 04/16/87 22.00 No
117 300 PPM Ruffled Fur 05/28/1987 04/16/87 43.00 No
117 300 PPM Discharge Vaginal Area, Yellow 06/25/1987 04/16/87 71.00 No
118 300 PPM Hyperactive 04/22/1987 04/16/87 7.00 No
118 300 PPM Hyperactive 04/23/1987 04/16/87 8.00 No
118 300 PPM Hyperactive 05/07/1987 04/16/87 22.00 No
118 300 PPM Wound Tail 05/07/1987 04/16/87 22.00 No
118 300 PPM Ruffled Fur 05/14/1987 04/16/87 29.00 No
118 300 PPM Wound Tail 05/14/1987 04/16/87 29.00 No
118 300 PPM Wound Tail 05/21/1987 04/16/87 36.00 No
118 300 PPM Ruffled Fur 05/21/1987 04/16/87 36.00 No
118 300 PPM Hyperactive 05/28/1987 04/16/87 43.00 No
118 300 PPM Ruffled Fur 07/01/1987 04/16/87 77.00 No
119 300 PPM Hyperactive 04/22/1987 04/16/87 7.00 No
119 300 PPM Hyperactive 04/23/1987 04/16/87 8.00 No
119 300 PPM Discoloration Nose, Black 04/30/1987 04/16/87 15.00 No
119 300 PPM Wound Nose 04/30/1987 04/16/87 15.00 No
119 300 PPM Ruffled Fur 05/07/1987 04/16/87 22.00 No
119 300 PPM Hyperactive 05/07/1987 04/16/87 22.00 No
119 300 PPM Discharge Right Eye, Red 05/07/1987 04/16/87 22.00 No
119 300 PPM Ruffled Fur 05/14/1987 04/16/87 29.00 No
119 300 PPM Discharge Right Eye, Red 05/14/1987 04/16/87 29.00 No
119 300 PPM Ruffled Fur 05/28/1987 04/16/87 43.00 No
119 300 PPM Hyperactive 05/28/1987 04/16/87 43.00 No
119 300 PPM Ruffled Fur 06/04/1987 04/16/87 50.00 No
119 300 PPM Wound Tail 06/18/1987 04/16/87 64.00 No
119 300 PPM Discharge Right Eye, Red 07/09/1987 04/16/87 85.00 No
120 300 PPM Ruffled Fur 04/23/1987 04/16/87 8.00 No
120 300 PPM Ruffled Fur 04/30/1987 04/16/87 15.00 No
120 300 PPM Ruffled Fur 05/07/1987 04/16/87 22.00 No
120 300 PPM Ruffled Fur 05/14/1987 04/16/87 29.00 No
120 300 PPM Ruffled Fur 05/21/1987 04/16/87 36.00 No
120 300 PPM Ruffled Fur 05/28/1987 04/16/87 43.00 No