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Current Search Critera

Short-Term Study Individual Animal Clinical Observations

Study Information:

Chemical Name: Isobutyl nitrite
CASRN: ="542-56-3"
Study Number: C61052B
Exposure Route: RESPIRATORY EXPOSURE WHOLE BODY
TDMS Number: 0518502
Sex: Female
Strain and Species: B6C3F1 Mice

Animal Number Dose Group Clinical Observation Qualifier Incident Number Observation Date First Dose Date Days On Study Removal Observation
11 Vehicle Control Alopecia Body Ventral 07/22/1987 04/17/87 97.00 Yes
12 Vehicle Control Alopecia Body Dorsal 07/17/1987 04/17/87 92.00 No
12 Vehicle Control Alopecia Body Dorsal 07/22/1987 04/17/87 97.00 Yes
14 Vehicle Control Alopecia Body Ventral 06/26/1987 04/17/87 71.00 No
14 Vehicle Control Alopecia Body Ventral 07/02/1987 04/17/87 77.00 No
14 Vehicle Control Alopecia Body Ventral 07/10/1987 04/17/87 85.00 No
14 Vehicle Control Alopecia Body Ventral 07/17/1987 04/17/87 92.00 No
14 Vehicle Control Alopecia Body Ventral 07/22/1987 04/17/87 97.00 Yes
15 Vehicle Control Alopecia Body Ventral 07/17/1987 04/17/87 92.00 No
15 Vehicle Control Alopecia Body Ventral 07/22/1987 04/17/87 97.00 Yes
17 Vehicle Control Alopecia Body Ventral 05/15/1987 04/17/87 29.00 No
17 Vehicle Control Alopecia Body Ventral 05/22/1987 04/17/87 36.00 No
17 Vehicle Control Alopecia Body Ventral 05/29/1987 04/17/87 43.00 No
17 Vehicle Control Alopecia Body Ventral 06/05/1987 04/17/87 50.00 No
17 Vehicle Control Alopecia Body Ventral 06/12/1987 04/17/87 57.00 No
17 Vehicle Control Alopecia Body Ventral 06/19/1987 04/17/87 64.00 No
17 Vehicle Control Alopecia Body Ventral 06/26/1987 04/17/87 71.00 No
17 Vehicle Control Alopecia Body Ventral 07/02/1987 04/17/87 77.00 No
17 Vehicle Control Alopecia Body Ventral 07/10/1987 04/17/87 85.00 No
17 Vehicle Control Alopecia Body Ventral 07/17/1987 04/17/87 92.00 No
17 Vehicle Control Alopecia Body Ventral 07/22/1987 04/17/87 97.00 Yes
19 Vehicle Control Alopecia Body Ventral 06/26/1987 04/17/87 71.00 No
19 Vehicle Control Alopecia Body Ventral 07/02/1987 04/17/87 77.00 No
19 Vehicle Control Alopecia Body Ventral 07/10/1987 04/17/87 85.00 No
20 Vehicle Control Other 06/12/1987 04/17/87 57.00 No
20 Vehicle Control Other 06/19/1987 04/17/87 64.00 No
20 Vehicle Control Other 06/26/1987 04/17/87 71.00 No
20 Vehicle Control Other 07/02/1987 04/17/87 77.00 No
20 Vehicle Control Other 07/10/1987 04/17/87 85.00 No
20 Vehicle Control Other 07/17/1987 04/17/87 92.00 No
20 Vehicle Control Other 07/22/1987 04/17/87 97.00 Yes
35 10 PPM Alopecia Body Ventral 07/22/1987 04/17/87 97.00 Yes
38 10 PPM Alopecia Body Ventral 05/29/1987 04/17/87 43.00 No
38 10 PPM Alopecia Body Ventral 06/05/1987 04/17/87 50.00 No
38 10 PPM Alopecia Body Ventral 06/12/1987 04/17/87 57.00 No
38 10 PPM Alopecia Body Ventral 06/19/1987 04/17/87 64.00 No
38 10 PPM Alopecia Body Ventral 06/26/1987 04/17/87 71.00 No
38 10 PPM Alopecia Body Ventral 07/02/1987 04/17/87 77.00 No
38 10 PPM Alopecia Body Ventral 07/10/1987 04/17/87 85.00 No
38 10 PPM Alopecia Body Ventral 07/17/1987 04/17/87 92.00 No
38 10 PPM Alopecia Body Ventral 07/22/1987 04/17/87 97.00 Yes
40 10 PPM Alopecia Body Ventral 06/12/1987 04/17/87 57.00 No
40 10 PPM Alopecia Body Ventral 06/19/1987 04/17/87 64.00 No
40 10 PPM Alopecia Body Ventral 06/26/1987 04/17/87 71.00 No
40 10 PPM Alopecia Body Ventral 07/02/1987 04/17/87 77.00 No
40 10 PPM Alopecia Body Ventral 07/10/1987 04/17/87 85.00 No
40 10 PPM Alopecia Body Ventral 07/17/1987 04/17/87 92.00 No
40 10 PPM Alopecia Body Ventral 07/22/1987 04/17/87 97.00 Yes
52 25 PPM Alopecia Body Ventral 05/29/1987 04/17/87 43.00 No
52 25 PPM Alopecia Body Ventral 06/05/1987 04/17/87 50.00 No
52 25 PPM Alopecia Body Ventral 06/12/1987 04/17/87 57.00 No
52 25 PPM Alopecia Body Ventral 06/19/1987 04/17/87 64.00 No
52 25 PPM Alopecia Body Ventral 06/26/1987 04/17/87 71.00 No
52 25 PPM Alopecia Body Ventral 07/02/1987 04/17/87 77.00 No
52 25 PPM Alopecia Body Ventral 07/10/1987 04/17/87 85.00 No
52 25 PPM Alopecia Body Ventral 07/17/1987 04/17/87 92.00 No
52 25 PPM Alopecia Body Ventral 07/22/1987 04/17/87 97.00 Yes
54 25 PPM Alopecia Body Ventral 06/26/1987 04/17/87 71.00 No
54 25 PPM Alopecia Body Ventral 07/02/1987 04/17/87 77.00 No
54 25 PPM Alopecia Body Ventral 07/10/1987 04/17/87 85.00 No
54 25 PPM Alopecia Body Ventral 07/17/1987 04/17/87 92.00 No
54 25 PPM Alopecia Body Ventral 07/22/1987 04/17/87 97.00 Yes
55 25 PPM Alopecia Body Ventral 05/29/1987 04/17/87 43.00 No
55 25 PPM Alopecia Body Ventral 06/05/1987 04/17/87 50.00 No
55 25 PPM Alopecia Body Ventral 06/12/1987 04/17/87 57.00 No
55 25 PPM Alopecia Body Ventral 06/19/1987 04/17/87 64.00 No
55 25 PPM Alopecia Body Ventral 06/26/1987 04/17/87 71.00 No
55 25 PPM Alopecia Body Ventral 07/02/1987 04/17/87 77.00 No
55 25 PPM Alopecia Body Ventral 07/10/1987 04/17/87 85.00 No
55 25 PPM Alopecia Body Ventral 07/17/1987 04/17/87 92.00 No
55 25 PPM Alopecia Body Ventral 07/22/1987 04/17/87 97.00 Yes
56 25 PPM Alopecia Body Ventral 05/15/1987 04/17/87 29.00 No
56 25 PPM Alopecia Body Ventral 05/22/1987 04/17/87 36.00 No
56 25 PPM Alopecia Body Ventral 05/29/1987 04/17/87 43.00 No
56 25 PPM Alopecia Body Ventral 06/05/1987 04/17/87 50.00 No
56 25 PPM Alopecia Body Ventral 06/12/1987 04/17/87 57.00 No
56 25 PPM Alopecia Body Ventral 06/19/1987 04/17/87 64.00 No
56 25 PPM Alopecia Body Ventral 06/26/1987 04/17/87 71.00 No
56 25 PPM Alopecia Body Ventral 07/02/1987 04/17/87 77.00 No
56 25 PPM Alopecia Body Ventral 07/10/1987 04/17/87 85.00 No
56 25 PPM Alopecia Body Ventral 07/17/1987 04/17/87 92.00 No
56 25 PPM Alopecia Body Ventral 07/22/1987 04/17/87 97.00 Yes
59 25 PPM Alopecia Body Ventral 07/17/1987 04/17/87 92.00 No
71 75 PPM Alopecia Body Ventral 07/10/1987 04/17/87 85.00 No
71 75 PPM Alopecia Body Ventral 07/17/1987 04/17/87 92.00 No
71 75 PPM Alopecia Body Ventral 07/22/1987 04/17/87 97.00 Yes
77 75 PPM Alopecia Body Ventral 07/10/1987 04/17/87 85.00 No
77 75 PPM Alopecia Body Ventral 07/17/1987 04/17/87 92.00 No
77 75 PPM Alopecia Body Ventral 07/22/1987 04/17/87 97.00 Yes
91 150 PPM Alopecia Body Ventral 05/29/1987 04/17/87 43.00 No
91 150 PPM Alopecia Body Ventral 06/05/1987 04/17/87 50.00 No
91 150 PPM Alopecia Body Ventral 06/12/1987 04/17/87 57.00 No
91 150 PPM Alopecia Body Ventral 06/19/1987 04/17/87 64.00 No
91 150 PPM Wound Face 06/23/1987 04/17/87 68.00 Yes
91 150 PPM Emaciated 06/23/1987 04/17/87 68.00 Yes
91 150 PPM Alopecia Body Ventral 06/23/1987 04/17/87 68.00 Yes
92 150 PPM Alopecia Body Ventral 07/02/1987 04/17/87 77.00 No
92 150 PPM Alopecia Body Ventral 07/10/1987 04/17/87 85.00 No
92 150 PPM Alopecia Body Ventral 07/17/1987 04/17/87 92.00 No
92 150 PPM Alopecia Body Ventral 07/22/1987 04/17/87 97.00 Yes
94 150 PPM Alopecia Body Ventral 07/17/1987 04/17/87 92.00 No
96 150 PPM Alopecia Body Ventral 06/12/1987 04/17/87 57.00 No
96 150 PPM Alopecia Body Ventral 06/19/1987 04/17/87 64.00 No
96 150 PPM Alopecia Body Ventral 06/26/1987 04/17/87 71.00 No
96 150 PPM Alopecia Body Ventral 07/02/1987 04/17/87 77.00 No
96 150 PPM Alopecia Body Ventral 07/10/1987 04/17/87 85.00 No
96 150 PPM Alopecia Body Ventral 07/17/1987 04/17/87 92.00 No
96 150 PPM Alopecia Body Ventral 07/22/1987 04/17/87 97.00 Yes
97 150 PPM Alopecia Body Ventral 05/29/1987 04/17/87 43.00 No
97 150 PPM Alopecia Body Ventral 06/26/1987 04/17/87 71.00 No
97 150 PPM Alopecia Body Ventral 07/02/1987 04/17/87 77.00 No
97 150 PPM Alopecia Body Ventral 07/10/1987 04/17/87 85.00 No
97 150 PPM Alopecia Body Ventral 07/17/1987 04/17/87 92.00 No
97 150 PPM Alopecia Body Ventral 07/22/1987 04/17/87 97.00 Yes
98 150 PPM Alopecia Body Ventral 07/02/1987 04/17/87 77.00 No
98 150 PPM Alopecia Body Ventral 07/10/1987 04/17/87 85.00 No
100 150 PPM Alopecia Body Ventral 05/29/1987 04/17/87 43.00 No
100 150 PPM Alopecia Body Ventral 06/05/1987 04/17/87 50.00 No
100 150 PPM Alopecia Body Ventral 06/12/1987 04/17/87 57.00 No
100 150 PPM Alopecia Body Ventral 06/19/1987 04/17/87 64.00 No
100 150 PPM Alopecia Body Ventral 06/26/1987 04/17/87 71.00 No
100 150 PPM Alopecia Body Ventral 07/02/1987 04/17/87 77.00 No
100 150 PPM Alopecia Body Ventral 07/10/1987 04/17/87 85.00 No
100 150 PPM Alopecia Body Ventral 07/17/1987 04/17/87 92.00 No
100 150 PPM Alopecia Body Ventral 07/22/1987 04/17/87 97.00 Yes
115 300 PPM Alopecia Body Ventral 05/29/1987 04/17/87 43.00 No
115 300 PPM Alopecia Body Ventral 06/05/1987 04/17/87 50.00 No
115 300 PPM Alopecia Body Ventral 06/12/1987 04/17/87 57.00 No
115 300 PPM Alopecia Body Ventral 06/19/1987 04/17/87 64.00 No
115 300 PPM Alopecia Body Ventral 06/26/1987 04/17/87 71.00 No
115 300 PPM Alopecia Body Ventral 07/02/1987 04/17/87 77.00 No
115 300 PPM Alopecia Body Ventral 07/10/1987 04/17/87 85.00 No
115 300 PPM Alopecia Body Ventral 07/17/1987 04/17/87 92.00 No
115 300 PPM Alopecia Body Ventral 07/22/1987 04/17/87 97.00 Yes
116 300 PPM Alopecia Body Ventral 05/22/1987 04/17/87 36.00 No
116 300 PPM Alopecia Body Ventral 05/29/1987 04/17/87 43.00 No
116 300 PPM Alopecia Body Ventral 06/05/1987 04/17/87 50.00 No
116 300 PPM Alopecia Body Ventral 06/12/1987 04/17/87 57.00 No
116 300 PPM Alopecia Body Ventral 06/19/1987 04/17/87 64.00 No
116 300 PPM Alopecia Body Ventral 06/26/1987 04/17/87 71.00 No
116 300 PPM Alopecia Body Ventral 07/02/1987 04/17/87 77.00 No
116 300 PPM Alopecia Body Ventral 07/10/1987 04/17/87 85.00 No
116 300 PPM Alopecia Body Ventral 07/17/1987 04/17/87 92.00 No
116 300 PPM Alopecia Body Ventral 07/22/1987 04/17/87 97.00 Yes
117 300 PPM Abnormal Posture 06/05/1987 04/17/87 50.00 No
117 300 PPM Abnormal Posture 07/17/1987 04/17/87 92.00 No
117 300 PPM Abnormal Posture 07/17/1987 04/17/87 92.00 Yes
117 300 PPM Dyspnea 07/17/1987 04/17/87 92.00 Yes
117 300 PPM Ruffled Fur 07/17/1987 04/17/87 92.00 No
118 300 PPM Alopecia Body Ventral 07/17/1987 04/17/87 92.00 No
118 300 PPM Alopecia Body Ventral 07/22/1987 04/17/87 97.00 Yes
120 300 PPM Alopecia Body Ventral 07/22/1987 04/17/87 97.00 Yes