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Current Search Critera

Short-Term Study Individual Animal Clinical Observations

Study Information:

Chemical Name: Methacrylonitrile
CASRN: ="126-98-7"
Study Number: C88050
Exposure Route:
TDMS Number: 8805001
Sex: Male
Strain and Species: F 344/N Rats

Animal Number Dose Group Clinical Observation Qualifier Incident Number Observation Date First Dose Date Days On Study Removal Observation
5 Untreated Control Nasal/Eye Discharge 02/16/1992 02/06/92 11.00 No
11 0.6 G/L Nasal/Eye Discharge 02/16/1992 02/06/92 11.00 No
11 0.6 G/L Ruffled Fur 02/16/1992 02/06/92 11.00 No
13 0.6 G/L Ruffled Fur 02/16/1992 02/06/92 11.00 No
13 0.6 G/L Nasal/Eye Discharge 02/16/1992 02/06/92 11.00 No
14 0.6 G/L Nasal/Eye Discharge 02/16/1992 02/06/92 11.00 No
16 1.2 G/L Nasal/Eye Discharge 02/16/1992 02/06/92 11.00 No
18 1.2 G/L Nasal/Eye Discharge 02/11/1992 02/06/92 6.00 No
18 1.2 G/L Nasal/Eye Discharge 02/12/1992 02/06/92 7.00 No
18 1.2 G/L Nasal/Eye Discharge 02/13/1992 02/06/92 8.00 No
18 1.2 G/L Nasal/Eye Discharge 02/14/1992 02/06/92 9.00 No
18 1.2 G/L Nasal/Eye Discharge 02/15/1992 02/06/92 10.00 No
18 1.2 G/L Ruffled Fur 02/16/1992 02/06/92 11.00 No
18 1.2 G/L Nasal/Eye Discharge 02/16/1992 02/06/92 11.00 No
18 1.2 G/L Nasal/Eye Discharge 02/17/1992 02/06/92 12.00 No
18 1.2 G/L Nasal/Eye Discharge 02/18/1992 02/06/92 13.00 No
18 1.2 G/L Nasal/Eye Discharge 02/19/1992 02/06/92 14.00 No
18 1.2 G/L Nasal/Eye Discharge 02/20/1992 02/06/92 15.00 Yes
18 1.2 G/L Nasal/Eye Discharge 02/20/1992 02/06/92 15.00 No
19 1.2 G/L Nasal/Eye Discharge 02/09/1992 02/06/92 4.00 No
19 1.2 G/L Ruffled Fur 02/16/1992 02/06/92 11.00 No
20 1.2 G/L Nasal/Eye Discharge 02/09/1992 02/06/92 4.00 No
20 1.2 G/L Nasal/Eye Discharge 02/13/1992 02/06/92 8.00 No
20 1.2 G/L Ruffled Fur 02/16/1992 02/06/92 11.00 No
21 2.4 G/L Thin 02/13/1992 02/06/92 8.00 No
21 2.4 G/L Thin 02/14/1992 02/06/92 9.00 No
21 2.4 G/L Thin 02/15/1992 02/06/92 10.00 No
21 2.4 G/L Nasal/Eye Discharge 02/16/1992 02/06/92 11.00 No
21 2.4 G/L Ruffled Fur 02/16/1992 02/06/92 11.00 No
21 2.4 G/L Thin 02/16/1992 02/06/92 11.00 No
21 2.4 G/L Thin 02/17/1992 02/06/92 12.00 No
21 2.4 G/L Thin 02/18/1992 02/06/92 13.00 No
21 2.4 G/L Thin 02/19/1992 02/06/92 14.00 No
21 2.4 G/L Thin 02/20/1992 02/06/92 15.00 Yes
21 2.4 G/L Thin 02/20/1992 02/06/92 15.00 No
22 2.4 G/L Thin 02/13/1992 02/06/92 8.00 No
22 2.4 G/L Nasal/Eye Discharge 02/13/1992 02/06/92 8.00 No
22 2.4 G/L Thin 02/14/1992 02/06/92 9.00 No
22 2.4 G/L Thin 02/15/1992 02/06/92 10.00 No
22 2.4 G/L Thin 02/16/1992 02/06/92 11.00 No
22 2.4 G/L Nasal/Eye Discharge 02/16/1992 02/06/92 11.00 No
22 2.4 G/L Ruffled Fur 02/16/1992 02/06/92 11.00 No
22 2.4 G/L Thin 02/17/1992 02/06/92 12.00 No
22 2.4 G/L Thin 02/18/1992 02/06/92 13.00 No
22 2.4 G/L Thin 02/19/1992 02/06/92 14.00 No
22 2.4 G/L Thin 02/20/1992 02/06/92 15.00 Yes
22 2.4 G/L Thin 02/20/1992 02/06/92 15.00 No
23 2.4 G/L Nasal/Eye Discharge 02/13/1992 02/06/92 8.00 No
23 2.4 G/L Thin 02/13/1992 02/06/92 8.00 No
23 2.4 G/L Thin 02/14/1992 02/06/92 9.00 No
23 2.4 G/L Thin 02/15/1992 02/06/92 10.00 No
23 2.4 G/L Ruffled Fur 02/15/1992 02/06/92 10.00 No
23 2.4 G/L Ruffled Fur 02/16/1992 02/06/92 11.00 No
23 2.4 G/L Nasal/Eye Discharge 02/16/1992 02/06/92 11.00 No
23 2.4 G/L Thin 02/16/1992 02/06/92 11.00 No
23 2.4 G/L Thin 02/17/1992 02/06/92 12.00 No
23 2.4 G/L Thin 02/18/1992 02/06/92 13.00 No
23 2.4 G/L Thin 02/19/1992 02/06/92 14.00 No
23 2.4 G/L Thin 02/20/1992 02/06/92 15.00 Yes
23 2.4 G/L Thin 02/20/1992 02/06/92 15.00 No
24 2.4 G/L Nasal/Eye Discharge 02/13/1992 02/06/92 8.00 No
24 2.4 G/L Thin 02/13/1992 02/06/92 8.00 No
24 2.4 G/L Thin 02/14/1992 02/06/92 9.00 No
24 2.4 G/L Thin 02/15/1992 02/06/92 10.00 No
24 2.4 G/L Thin 02/16/1992 02/06/92 11.00 No
24 2.4 G/L Ruffled Fur 02/16/1992 02/06/92 11.00 No
24 2.4 G/L Nasal/Eye Discharge 02/16/1992 02/06/92 11.00 No
24 2.4 G/L Thin 02/17/1992 02/06/92 12.00 No
24 2.4 G/L Thin 02/18/1992 02/06/92 13.00 No
24 2.4 G/L Thin 02/19/1992 02/06/92 14.00 No
24 2.4 G/L Thin 02/20/1992 02/06/92 15.00 No
24 2.4 G/L Thin 02/20/1992 02/06/92 15.00 Yes
25 2.4 G/L Nasal/Eye Discharge 02/11/1992 02/06/92 6.00 No
25 2.4 G/L Thin 02/13/1992 02/06/92 8.00 No
25 2.4 G/L Thin 02/14/1992 02/06/92 9.00 No
25 2.4 G/L Thin 02/15/1992 02/06/92 10.00 No
25 2.4 G/L Thin 02/16/1992 02/06/92 11.00 No
25 2.4 G/L Ruffled Fur 02/16/1992 02/06/92 11.00 No
25 2.4 G/L Thin 02/17/1992 02/06/92 12.00 No
25 2.4 G/L Thin 02/18/1992 02/06/92 13.00 No
25 2.4 G/L Thin 02/19/1992 02/06/92 14.00 No
25 2.4 G/L Thin 02/20/1992 02/06/92 15.00 No
25 2.4 G/L Thin 02/20/1992 02/06/92 15.00 Yes
26 4.8 G/L Thin 02/09/1992 02/06/92 4.00 No
26 4.8 G/L Nasal/Eye Discharge 02/13/1992 02/06/92 8.00 No
26 4.8 G/L Thin 02/13/1992 02/06/92 8.00 No
26 4.8 G/L Thin 02/14/1992 02/06/92 9.00 No
26 4.8 G/L Ruffled Fur 02/15/1992 02/06/92 10.00 No
26 4.8 G/L Thin 02/15/1992 02/06/92 10.00 No
26 4.8 G/L Nasal/Eye Discharge 02/16/1992 02/06/92 11.00 No
26 4.8 G/L Thin 02/16/1992 02/06/92 11.00 No
26 4.8 G/L Ruffled Fur 02/16/1992 02/06/92 11.00 No
26 4.8 G/L Thin 02/17/1992 02/06/92 12.00 No
26 4.8 G/L Thin 02/18/1992 02/06/92 13.00 No
26 4.8 G/L Thin 02/19/1992 02/06/92 14.00 No
26 4.8 G/L Thin 02/20/1992 02/06/92 15.00 No
26 4.8 G/L Thin 02/20/1992 02/06/92 15.00 Yes
27 4.8 G/L Nasal/Eye Discharge 02/08/1992 02/06/92 3.00 No
27 4.8 G/L Nasal/Eye Discharge 02/09/1992 02/06/92 4.00 No
27 4.8 G/L Nasal/Eye Discharge 02/10/1992 02/06/92 5.00 No
27 4.8 G/L Nasal/Eye Discharge 02/11/1992 02/06/92 6.00 No
27 4.8 G/L Nasal/Eye Discharge 02/12/1992 02/06/92 7.00 No
27 4.8 G/L Thin 02/13/1992 02/06/92 8.00 No
27 4.8 G/L Nasal/Eye Discharge 02/13/1992 02/06/92 8.00 No
27 4.8 G/L Nasal/Eye Discharge 02/14/1992 02/06/92 9.00 No
27 4.8 G/L Thin 02/14/1992 02/06/92 9.00 No
27 4.8 G/L Ruffled Fur 02/15/1992 02/06/92 10.00 No
27 4.8 G/L Nasal/Eye Discharge 02/15/1992 02/06/92 10.00 No
27 4.8 G/L Thin 02/15/1992 02/06/92 10.00 No
27 4.8 G/L Thin 02/16/1992 02/06/92 11.00 No
27 4.8 G/L Ruffled Fur 02/16/1992 02/06/92 11.00 No
27 4.8 G/L Nasal/Eye Discharge 02/16/1992 02/06/92 11.00 No
27 4.8 G/L Thin 02/17/1992 02/06/92 12.00 No
27 4.8 G/L Thin 02/18/1992 02/06/92 13.00 No
27 4.8 G/L Thin 02/19/1992 02/06/92 14.00 No
27 4.8 G/L Thin 02/20/1992 02/06/92 15.00 No
27 4.8 G/L Thin 02/20/1992 02/06/92 15.00 Yes
28 4.8 G/L Nasal/Eye Discharge 02/07/1992 02/06/92 2.00 No
28 4.8 G/L Nasal/Eye Discharge 02/08/1992 02/06/92 3.00 No
28 4.8 G/L Thin 02/09/1992 02/06/92 4.00 No
28 4.8 G/L Nasal/Eye Discharge 02/09/1992 02/06/92 4.00 No
28 4.8 G/L Nasal/Eye Discharge 02/10/1992 02/06/92 5.00 No
28 4.8 G/L Nasal/Eye Discharge 02/11/1992 02/06/92 6.00 No
28 4.8 G/L Nasal/Eye Discharge 02/12/1992 02/06/92 7.00 No
28 4.8 G/L Nasal/Eye Discharge 02/13/1992 02/06/92 8.00 No
28 4.8 G/L Thin 02/13/1992 02/06/92 8.00 No
28 4.8 G/L Nasal/Eye Discharge 02/14/1992 02/06/92 9.00 No
28 4.8 G/L Thin 02/14/1992 02/06/92 9.00 No
28 4.8 G/L Thin 02/15/1992 02/06/92 10.00 No
28 4.8 G/L Nasal/Eye Discharge 02/15/1992 02/06/92 10.00 No
28 4.8 G/L Ruffled Fur 02/15/1992 02/06/92 10.00 No
28 4.8 G/L Thin 02/16/1992 02/06/92 11.00 No
28 4.8 G/L Nasal/Eye Discharge 02/16/1992 02/06/92 11.00 No
28 4.8 G/L Ruffled Fur 02/16/1992 02/06/92 11.00 No
28 4.8 G/L Thin 02/17/1992 02/06/92 12.00 No
28 4.8 G/L Thin 02/18/1992 02/06/92 13.00 No
28 4.8 G/L Thin 02/19/1992 02/06/92 14.00 No
28 4.8 G/L Thin 02/20/1992 02/06/92 15.00 Yes
28 4.8 G/L Thin 02/20/1992 02/06/92 15.00 No
29 4.8 G/L Nasal/Eye Discharge 02/09/1992 02/06/92 4.00 No
29 4.8 G/L Nasal/Eye Discharge 02/10/1992 02/06/92 5.00 No
29 4.8 G/L Nasal/Eye Discharge 02/11/1992 02/06/92 6.00 No
29 4.8 G/L Nasal/Eye Discharge 02/12/1992 02/06/92 7.00 No
29 4.8 G/L Thin 02/13/1992 02/06/92 8.00 No
29 4.8 G/L Thin 02/14/1992 02/06/92 9.00 No
29 4.8 G/L Thin 02/15/1992 02/06/92 10.00 No
29 4.8 G/L Ruffled Fur 02/15/1992 02/06/92 10.00 No
29 4.8 G/L Thin 02/16/1992 02/06/92 11.00 No
29 4.8 G/L Nasal/Eye Discharge 02/16/1992 02/06/92 11.00 No
29 4.8 G/L Ruffled Fur 02/16/1992 02/06/92 11.00 No
29 4.8 G/L Thin 02/17/1992 02/06/92 12.00 No
29 4.8 G/L Thin 02/18/1992 02/06/92 13.00 No
29 4.8 G/L Thin 02/19/1992 02/06/92 14.00 No
29 4.8 G/L Thin 02/20/1992 02/06/92 15.00 No
29 4.8 G/L Thin 02/20/1992 02/06/92 15.00 Yes
30 4.8 G/L Nasal/Eye Discharge 02/12/1992 02/06/92 7.00 No
30 4.8 G/L Thin 02/13/1992 02/06/92 8.00 No
30 4.8 G/L Thin 02/14/1992 02/06/92 9.00 No
30 4.8 G/L Thin 02/15/1992 02/06/92 10.00 No
30 4.8 G/L Ruffled Fur 02/15/1992 02/06/92 10.00 No
30 4.8 G/L Ruffled Fur 02/16/1992 02/06/92 11.00 No
30 4.8 G/L Thin 02/16/1992 02/06/92 11.00 No
30 4.8 G/L Nasal/Eye Discharge 02/16/1992 02/06/92 11.00 No
30 4.8 G/L Thin 02/17/1992 02/06/92 12.00 No
30 4.8 G/L Thin 02/18/1992 02/06/92 13.00 No
30 4.8 G/L Thin 02/19/1992 02/06/92 14.00 No
30 4.8 G/L Thin 02/20/1992 02/06/92 15.00 Yes
30 4.8 G/L Thin 02/20/1992 02/06/92 15.00 No