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Current Search Critera

Short-Term Study Individual Animal Clinical Observations

Study Information:

Chemical Name: Methacrylonitrile
CASRN: ="126-98-7"
Study Number: C88050
Exposure Route: GAVAGE
TDMS Number: 8805003
Sex: Male
Strain and Species: F 344/N Rats

Animal Number Dose Group Clinical Observation Qualifier Incident Number Observation Date First Dose Date Days On Study Removal Observation
2 Vehicle Control Nasal/Eye Discharge 10/15/1992 07/13/92 95.00 Yes
15 7.5 MG/KG Nasal/Eye Discharge 10/15/1992 07/13/92 95.00 Yes
24 15.0 MG/KG Nasal/Eye Discharge 09/14/1992 07/13/92 64.00 No
148 15 MG/KG Nasal/Eye Discharge 07/27/1992 07/13/92 8.00 No
148 15 MG/KG Ulcer/Abscess Head 1 07/27/1992 07/13/92 8.00 No
148 15 MG/KG Eye Abnormality 07/27/1992 07/13/92 8.00 No
148 15 MG/KG Eye Abnormality 08/03/1992 07/13/92 15.00 No
148 15 MG/KG Eye Abnormality 08/10/1992 07/13/92 22.00 No
148 15 MG/KG Eye Abnormality 08/17/1992 07/13/92 29.00 No
148 15 MG/KG Eye Abnormality 08/20/1992 07/13/92 32.00 Yes
152 30 MG/KG Eye Abnormality 08/03/1992 07/13/92 15.00 No
166 60 MG/KG Eye Abnormality 08/10/1992 07/13/92 22.00 No
171 120 MG/KG Tremors 07/20/1992 07/13/92 1.00 Yes
171 120 MG/KG Ataxia 07/20/1992 07/13/92 1.00 Yes
171 120 MG/KG Abnormal Breathing 07/20/1992 07/13/92 1.00 Yes
171 120 MG/KG Lethargic 07/20/1992 07/13/92 1.00 Yes
174 120 MG/KG Ataxia 07/20/1992 07/13/92 1.00 Yes
174 120 MG/KG Tremors 07/20/1992 07/13/92 1.00 Yes
174 120 MG/KG Lethargic 07/20/1992 07/13/92 1.00 Yes
174 120 MG/KG Abnormal Breathing 07/20/1992 07/13/92 1.00 Yes
180 120 MG/KG Lethargic 07/21/1992 07/13/92 2.00 Yes
180 120 MG/KG Abnormal Breathing 07/21/1992 07/13/92 2.00 Yes