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Short-Term Study Individual Animal Clinical Observations

Study Information:

Chemical Name: Sodium cyanide
CASRN: ="143-33-9"
Study Number: C62124B
Exposure Route: DOSED WATER
TDMS Number: 0515905
Sex: Male
Strain and Species: F 344/N Rats

Animal Number Dose Group Clinical Observation Qualifier Incident Number Observation Date First Dose Date Days On Study Removal Observation
2 Vehicle Control Reddened Eye 01/17/1989 11/07/88 72.00 No
2 Vehicle Control Reddened Eye 01/31/1989 11/07/88 86.00 No
4 Vehicle Control Reddened Eye 01/31/1989 11/07/88 86.00 No
5 Vehicle Control Reddened Eye 01/31/1989 11/07/88 86.00 No
6 Vehicle Control Reddened Eye 01/31/1989 11/07/88 86.00 No
7 Vehicle Control Alopecia 01/03/1989 11/07/88 58.00 No
7 Vehicle Control Alopecia 01/10/1989 11/07/88 65.00 No
7 Vehicle Control Alopecia 01/17/1989 11/07/88 72.00 No
7 Vehicle Control Reddened Eye 01/31/1989 11/07/88 86.00 No
8 Vehicle Control Reddened Eye 01/31/1989 11/07/88 86.00 No
8 Vehicle Control Alopecia 02/08/1989 11/07/88 94.00 Yes
9 Vehicle Control Reddened Eye 01/31/1989 11/07/88 86.00 No
10 Vehicle Control Reddened Eye 01/31/1989 11/07/88 86.00 No
12 0.0003 % Reddened Eye 01/31/1989 11/07/88 86.00 No
16 0.0003 % Reddened Eye 01/31/1989 11/07/88 86.00 No
20 0.0003 % Reddened Eye 01/31/1989 11/07/88 86.00 No
23 0.001 % Reddened Eye 01/31/1989 11/07/88 86.00 No
31 0.003 % Alopecia 11/29/1988 11/07/88 23.00 No
32 0.003 % Reddened Eye 01/31/1989 11/07/88 86.00 No
33 0.003 % Reddened Eye 01/31/1989 11/07/88 86.00 No
35 0.003 % Reddened Eye 01/31/1989 11/07/88 86.00 No
36 0.003 % Reddened Eye 01/31/1989 11/07/88 86.00 No
38 0.003 % Reddened Eye 01/31/1989 11/07/88 86.00 No
39 0.003 % Reddened Eye 01/31/1989 11/07/88 86.00 No
41 0.01 % Sore Right Eye 01/10/1989 11/07/88 65.00 No
41 0.01 % Reddened Eye 01/31/1989 11/07/88 86.00 No
42 0.01 % Reddened Eye 01/31/1989 11/07/88 86.00 No
45 0.01 % Reddened Eye 01/31/1989 11/07/88 86.00 No
47 0.01 % Reddened Eye 01/31/1989 11/07/88 86.00 No
48 0.01 % Reddened Eye 01/31/1989 11/07/88 86.00 No
49 0.01 % Reddened Eye 01/31/1989 11/07/88 86.00 No
51 0.03 % Reddened Eye 01/31/1989 11/07/88 86.00 No
53 0.03 % Reddened Eye 01/31/1989 11/07/88 86.00 No
54 0.03 % Reddened Eye 01/31/1989 11/07/88 86.00 No
55 0.03 % Reddened Eye 01/31/1989 11/07/88 86.00 No
57 0.03 % Reddened Eye 01/31/1989 11/07/88 86.00 No
58 0.03 % Reddened Eye 01/31/1989 11/07/88 86.00 No
59 0.03 % Reddened Eye 01/31/1989 11/07/88 86.00 No
60 0.03 % Reddened Eye 01/31/1989 11/07/88 86.00 No
124 Vehicle Control Alopecia 11/07/1988 11/07/88 1.00 No
124 Vehicle Control Sore Nose 11/15/1988 11/07/88 9.00 No
124 Vehicle Control Head Tilted 01/31/1989 11/07/88 86.00 No
128 Vehicle Control Hyperactive 11/22/1988 11/07/88 16.00 No
128 Vehicle Control Hypoactivity 11/29/1988 11/07/88 23.00 No
130 Vehicle Control Reddened Eye 11/15/1988 11/07/88 9.00 No
130 Vehicle Control Reddened Eye 11/22/1988 11/07/88 16.00 No
130 Vehicle Control Reddened Eye 11/29/1988 11/07/88 23.00 No
141 0.001 % Reddened Eye 12/06/1988 11/07/88 30.00 No
141 0.001 % Exophthalmos 12/13/1988 11/07/88 37.00 No
142 0.001 % Exophthalmos 11/15/1988 11/07/88 9.00 No
142 0.001 % Exophthalmos 11/22/1988 11/07/88 16.00 No
142 0.001 % Exophthalmos 11/29/1988 11/07/88 23.00 No
142 0.001 % Exophthalmos 12/06/1988 11/07/88 30.00 No
142 0.001 % Exophthalmos 12/20/1988 11/07/88 44.00 No
147 0.001 % Reddened Eye 11/15/1988 11/07/88 9.00 No
147 0.001 % Reddened Eye 11/29/1988 11/07/88 23.00 No
147 0.001 % Reddened Eye 12/06/1988 11/07/88 30.00 No
147 0.001 % Reddened Eye 12/20/1988 11/07/88 44.00 No
147 0.001 % Reddened Eye 01/10/1989 11/07/88 65.00 No
147 0.001 % Reddened Eye 01/17/1989 11/07/88 72.00 No
147 0.001 % Reddened Eye 01/24/1989 11/07/88 79.00 No
147 0.001 % Reddened Eye 01/31/1989 11/07/88 86.00 No
148 0.001 % Head Tilted 01/31/1989 11/07/88 86.00 No
149 0.001 % Reddened Eye 11/15/1988 11/07/88 9.00 No
150 0.001 % Reddened Eye 11/29/1988 11/07/88 23.00 No
151 0.003 % Exophthalmos 11/15/1988 11/07/88 9.00 No
151 0.003 % Exophthalmos 11/22/1988 11/07/88 16.00 No
151 0.003 % Exophthalmos 11/29/1988 11/07/88 23.00 No
151 0.003 % Exophthalmos 12/06/1988 11/07/88 30.00 No
151 0.003 % Exophthalmos 12/13/1988 11/07/88 37.00 No
151 0.003 % Head Tilted 01/03/1989 11/07/88 58.00 No
151 0.003 % Exophthalmos 01/03/1989 11/07/88 58.00 No
151 0.003 % Exophthalmos 01/24/1989 11/07/88 79.00 No
151 0.003 % Exophthalmos 01/31/1989 11/07/88 86.00 No
153 0.003 % Alopecia 01/31/1989 11/07/88 86.00 No
153 0.003 % Head Tilted 01/31/1989 11/07/88 86.00 No
159 0.003 % Opacity 01/31/1989 11/07/88 86.00 No
159 0.003 % Opacity 02/06/1989 11/07/88 92.00 Yes
163 0.01 % Alopecia 11/07/1988 11/07/88 1.00 No
163 0.01 % Alopecia 11/08/1988 11/07/88 2.00 No
163 0.01 % Alopecia 11/15/1988 11/07/88 9.00 No
163 0.01 % Alopecia 11/22/1988 11/07/88 16.00 No
163 0.01 % Alopecia 11/29/1988 11/07/88 23.00 No
163 0.01 % Alopecia 12/06/1988 11/07/88 30.00 No
170 0.01 % Opacity 11/15/1988 11/07/88 9.00 No
170 0.01 % Opacity 11/22/1988 11/07/88 16.00 No
170 0.01 % Reddened Eye 11/22/1988 11/07/88 16.00 No
170 0.01 % Opacity 11/29/1988 11/07/88 23.00 No
170 0.01 % Opacity 12/06/1988 11/07/88 30.00 No
170 0.01 % Opacity 12/13/1988 11/07/88 37.00 No
170 0.01 % Opacity 12/20/1988 11/07/88 44.00 No
170 0.01 % Opacity 12/27/1988 11/07/88 51.00 No
170 0.01 % Head Tilted 01/03/1989 11/07/88 58.00 No
170 0.01 % Opacity 01/03/1989 11/07/88 58.00 No
170 0.01 % Opacity 01/10/1989 11/07/88 65.00 No
170 0.01 % Head Tilted 01/10/1989 11/07/88 65.00 No
170 0.01 % Head Tilted 01/17/1989 11/07/88 72.00 No
170 0.01 % Opacity 01/17/1989 11/07/88 72.00 No
170 0.01 % Opacity 01/24/1989 11/07/88 79.00 No
170 0.01 % Micro-Ophthalmia 01/31/1989 11/07/88 86.00 No
170 0.01 % Opacity 01/31/1989 11/07/88 86.00 No
170 0.01 % Micro-Ophthalmia 02/06/1989 11/07/88 92.00 Yes
170 0.01 % Opacity 02/06/1989 11/07/88 92.00 Yes