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Short-Term Study Individual Animal Clinical Observations

Study Information:

Chemical Name: Tetrachlorophthalic anhydride
CASRN: ="117-08-8"
Study Number: C61585
Exposure Route: GAVAGE
TDMS Number: 0511301
Sex: Male
Strain and Species: F 344/N Rats

Animal Number Dose Group Clinical Observation Qualifier Incident Number Observation Date First Dose Date Days On Study Removal Observation
25 187 MG/KG Rales 08/27/1987 06/03/87 86.00 No
29 187 MG/KG Salivating 08/26/1987 06/03/87 84.00 Yes
29 187 MG/KG Nasal Discharge 08/26/1987 06/03/87 84.00 Yes
38 375 MG/KG Reddened Eye 06/25/1987 06/03/87 22.00 No
38 375 MG/KG Reddened Eye 07/02/1987 06/03/87 29.00 No
51 1500 MG/KG Wound Face, 6-10 Mm 07/07/1987 06/03/87 35.00 Yes
52 1500 MG/KG Missing Anatomy Left Front Leg 07/04/1987 06/03/87 32.00 Yes
52 1500 MG/KG Missing Anatomy Both Eyes 07/04/1987 06/03/87 32.00 Yes
52 1500 MG/KG Missing Anatomy Face 07/04/1987 06/03/87 32.00 Yes
53 1500 MG/KG Ruffled Fur 07/30/1987 06/03/87 58.00 No
53 1500 MG/KG Emaciated 08/06/1987 06/03/87 65.00 No
53 1500 MG/KG Ruffled Fur 08/06/1987 06/03/87 65.00 No
53 1500 MG/KG Hypoactivity 08/13/1987 06/03/87 72.00 No
53 1500 MG/KG Ruffled Fur 08/13/1987 06/03/87 72.00 No
53 1500 MG/KG Ruffled Fur 08/27/1987 06/03/87 86.00 No
54 1500 MG/KG Discoloration Hair, Yellow 07/05/1987 06/03/87 33.00 Yes
54 1500 MG/KG Missing Anatomy Right Eye 07/05/1987 06/03/87 33.00 Yes
55 1500 MG/KG Missing Anatomy Body Ventral 07/04/1987 06/03/87 32.00 Yes
56 1500 MG/KG Diarrhea 06/18/1987 06/03/87 15.00 No
56 1500 MG/KG Missing Anatomy Body Dorsal 07/26/1987 06/03/87 53.00 Yes
56 1500 MG/KG Missing Anatomy Body Ventral 07/26/1987 06/03/87 53.00 Yes
57 1500 MG/KG Missing Anatomy Left Rear Foot 08/15/1987 06/03/87 73.00 Yes
60 1500 MG/KG Urine Stain 08/06/1987 06/03/87 64.00 No
60 1500 MG/KG Urine Stain 08/27/1987 06/03/87 85.00 No