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Current Search Critera

Short-Term Study Individual Animal Clinical Observations

Study Information:

Chemical Name: Tetrahydrofuran
CASRN: ="109-99-9"
Study Number: C60560B
Exposure Route: RESPIRATORY EXPOSURE WHOLE BODY
TDMS Number: 0518102
Sex: Male
Strain and Species: B6C3F1 Mice

Animal Number Dose Group Clinical Observation Qualifier Incident Number Observation Date First Dose Date Days On Study Removal Observation
8 Vehicle Control Ruffled Fur 02/23/1987 02/12/87 12.00 No
10 Vehicle Control Alopecia Body Ventral, 3- 5 Mm 03/16/1987 02/12/87 33.00 No
10 Vehicle Control Alopecia Body Ventral, 16-20 Mm 03/23/1987 02/12/87 40.00 No
10 Vehicle Control Alopecia Body Ventral, 26 Or Gr 03/30/1987 02/12/87 47.00 No
10 Vehicle Control Alopecia Body Ventral, 26 Or Gr 04/06/1987 02/12/87 54.00 No
10 Vehicle Control Alopecia Body Ventral, 21-25 Mm 04/13/1987 02/12/87 61.00 No
10 Vehicle Control Alopecia Body Ventral, 26 Or Gr 04/20/1987 02/12/87 68.00 No
10 Vehicle Control Alopecia Body Ventral, 26 Or Gr 04/27/1987 02/12/87 75.00 No
10 Vehicle Control Alopecia Body Ventral, 26 Or Gr 05/04/1987 02/12/87 82.00 No
10 Vehicle Control Alopecia Body Ventral, 26 Or Gr 05/11/1987 02/12/87 89.00 No
201 66 PPM Alopecia Body Ventral, 16-20 Mm 03/16/1987 02/12/87 33.00 No
201 66 PPM Alopecia Body Ventral, 21-25 Mm 03/23/1987 02/12/87 40.00 No
201 66 PPM Alopecia Body Ventral, 16-20 Mm 03/30/1987 02/12/87 47.00 No
201 66 PPM Alopecia Body Ventral, 3- 5 Mm 04/06/1987 02/12/87 54.00 No
201 66 PPM Alopecia Body Ventral, 3- 5 Mm 04/27/1987 02/12/87 75.00 No
201 66 PPM Alopecia Body Ventral, 3- 5 Mm 05/11/1987 02/12/87 89.00 No
201 66 PPM Alopecia Body Ventral, 3- 5 Mm 05/15/1987 02/12/87 93.00 Yes
202 66 PPM Alopecia Body Ventral, 3- 5 Mm 03/30/1987 02/12/87 47.00 No
202 66 PPM Alopecia Body Ventral, 6-10 Mm 04/13/1987 02/12/87 61.00 No
202 66 PPM Alopecia Body Ventral, 3- 5 Mm 04/20/1987 02/12/87 68.00 No
202 66 PPM Alopecia Body Ventral, 6-10 Mm 05/04/1987 02/12/87 82.00 No
202 66 PPM Alopecia Body Ventral, 3- 5 Mm 05/11/1987 02/12/87 89.00 No
204 66 PPM Ruffled Fur 03/02/1987 02/12/87 19.00 No
204 66 PPM Ruffled Fur 03/09/1987 02/12/87 26.00 No
204 66 PPM Ruffled Fur 03/30/1987 02/12/87 47.00 No
208 66 PPM Alopecia Body Ventral, 3- 5 Mm 03/30/1987 02/12/87 47.00 No
208 66 PPM Ruffled Fur 04/06/1987 02/12/87 54.00 No
208 66 PPM Alopecia Body Ventral, 3- 5 Mm 04/06/1987 02/12/87 54.00 No
208 66 PPM Ruffled Fur 04/20/1987 02/12/87 68.00 No
208 66 PPM Alopecia Body Ventral, 11-15 Mm 04/20/1987 02/12/87 68.00 No
208 66 PPM Alopecia Body Ventral, 6-10 Mm 04/27/1987 02/12/87 75.00 No
208 66 PPM Alopecia Body Ventral, 11-15 Mm 05/04/1987 02/12/87 82.00 No
208 66 PPM Alopecia Body Ventral, 11-15 Mm 05/11/1987 02/12/87 89.00 No
209 66 PPM Ruffled Fur 03/30/1987 02/12/87 47.00 No
209 66 PPM Ruffled Fur 04/06/1987 02/12/87 54.00 No
210 66 PPM Ruffled Fur 02/23/1987 02/12/87 12.00 No
210 66 PPM Ruffled Fur 03/02/1987 02/12/87 19.00 No
210 66 PPM Ruffled Fur 03/09/1987 02/12/87 26.00 No
210 66 PPM Ruffled Fur 03/30/1987 02/12/87 47.00 No
210 66 PPM Ruffled Fur 04/06/1987 02/12/87 54.00 No
210 66 PPM Ruffled Fur 04/13/1987 02/12/87 61.00 No
403 200 PPM Ruffled Fur 03/02/1987 02/12/87 19.00 No
406 200 PPM Alopecia Body Ventral, 3- 5 Mm 03/30/1987 02/12/87 47.00 No
406 200 PPM Alopecia Body Ventral, 3- 5 Mm 04/13/1987 02/12/87 61.00 No
406 200 PPM Alopecia Body Ventral, 16-20 Mm 04/20/1987 02/12/87 68.00 No
406 200 PPM Alopecia Body Ventral, 16-20 Mm 04/27/1987 02/12/87 75.00 No
406 200 PPM Alopecia Body Ventral, 16-20 Mm 05/04/1987 02/12/87 82.00 No
406 200 PPM Alopecia Body Ventral, 21-25 Mm 05/11/1987 02/12/87 89.00 No
406 200 PPM Alopecia Body Ventral, 21-25 Mm 05/15/1987 02/12/87 93.00 Yes
407 200 PPM Alopecia Body Ventral, 3- 5 Mm 04/06/1987 02/12/87 54.00 No
407 200 PPM Ruffled Fur 04/13/1987 02/12/87 61.00 No
407 200 PPM Alopecia Body Ventral, 11-15 Mm 04/13/1987 02/12/87 61.00 No
407 200 PPM Ruffled Fur 04/20/1987 02/12/87 68.00 No
407 200 PPM Alopecia Body Ventral, 6-10 Mm 04/20/1987 02/12/87 68.00 No
407 200 PPM Alopecia Body Ventral, 11-15 Mm 05/04/1987 02/12/87 82.00 No
407 200 PPM Alopecia Body Ventral, 16-20 Mm 05/11/1987 02/12/87 89.00 No
410 200 PPM Ruffled Fur 02/23/1987 02/12/87 12.00 No
410 200 PPM Ruffled Fur 03/02/1987 02/12/87 19.00 No
410 200 PPM Ruffled Fur 03/09/1987 02/12/87 26.00 No
410 200 PPM Ruffled Fur 03/30/1987 02/12/87 47.00 No
410 200 PPM Ruffled Fur 04/06/1987 02/12/87 54.00 No
602 600 PPM Ruffled Fur 03/02/1987 02/12/87 19.00 No
602 600 PPM Ruffled Fur 04/06/1987 02/12/87 54.00 No
605 600 PPM Alopecia Body Ventral, 3- 5 Mm 05/04/1987 02/12/87 82.00 No
605 600 PPM Alopecia Body Ventral, 21-25 Mm 05/15/1987 02/12/87 93.00 Yes
606 600 PPM Alopecia Groin, 11-15 Mm 05/11/1987 02/12/87 89.00 No
606 600 PPM Alopecia Groin, 6-10 Mm 05/15/1987 02/12/87 93.00 Yes
608 600 PPM Alopecia Body Ventral, 3- 5 Mm 05/04/1987 02/12/87 82.00 No
608 600 PPM Alopecia Body Ventral, 6-10 Mm 05/15/1987 02/12/87 93.00 Yes
609 600 PPM Swelling Left Rear Leg 05/04/1987 02/12/87 82.00 No
610 600 PPM Alopecia Body Ventral, 16-20 Mm 03/09/1987 02/12/87 26.00 No
610 600 PPM Alopecia Body Ventral, 6-10 Mm 03/16/1987 02/12/87 33.00 No
610 600 PPM Alopecia Body Ventral, 16-20 Mm 03/23/1987 02/12/87 40.00 No
610 600 PPM Alopecia Body Ventral, 26 Or Gr 03/30/1987 02/12/87 47.00 No
610 600 PPM Alopecia Body Ventral, 26 Or Gr 04/06/1987 02/12/87 54.00 No
610 600 PPM Alopecia Right Front Leg, 6-10 Mm 04/06/1987 02/12/87 54.00 No
610 600 PPM Alopecia Body Ventral, 16-20 Mm 04/13/1987 02/12/87 61.00 No
610 600 PPM Alopecia Body Ventral, 26 Or Gr 04/20/1987 02/12/87 68.00 No
610 600 PPM Alopecia Body Ventral, 16-20 Mm 04/27/1987 02/12/87 75.00 No
610 600 PPM Alopecia Body Ventral, 3- 5 Mm 05/04/1987 02/12/87 82.00 No
610 600 PPM Alopecia Body Ventral, 26 Or Gr 05/11/1987 02/12/87 89.00 No
610 600 PPM Alopecia Body Ventral, 6-10 Mm 05/15/1987 02/12/87 93.00 Yes
801 1800 PPM Alopecia Body Ventral, 6-10 Mm 05/15/1987 02/12/87 93.00 Yes
803 1800 PPM Ruffled Fur 03/16/1987 02/12/87 33.00 No
803 1800 PPM Ruffled Fur 03/30/1987 02/12/87 47.00 No
803 1800 PPM Alopecia Head, 6-10 Mm 04/06/1987 02/12/87 54.00 No
803 1800 PPM Ruffled Fur 04/06/1987 02/12/87 54.00 No
803 1800 PPM Ruffled Fur 04/13/1987 02/12/87 61.00 No
803 1800 PPM Ruffled Fur 04/20/1987 02/12/87 68.00 No
803 1800 PPM Ruffled Fur 05/04/1987 02/12/87 82.00 No
808 1800 PPM Alopecia Body Dorsal, 6-10 Mm 05/15/1987 02/12/87 93.00 Yes
1001 5000 PPM Hypoactivity 02/12/1987 02/12/87 1.00 No
1002 5000 PPM Hypoactivity 02/12/1987 02/12/87 1.00 No
1003 5000 PPM Hypoactivity 02/12/1987 02/12/87 1.00 No
1004 5000 PPM Hypoactivity 02/12/1987 02/12/87 1.00 No
1004 5000 PPM Emaciated 02/16/1987 02/12/87 5.00 No
1005 5000 PPM Hypoactivity 02/12/1987 02/12/87 1.00 No
1008 5000 PPM Emaciated 02/16/1987 02/12/87 5.00 No
1010 5000 PPM Emaciated 03/05/1987 02/12/87 22.00 Yes
1010 5000 PPM Abnormal Posture 03/05/1987 02/12/87 22.00 Yes
1010 5000 PPM Dyspnea 03/05/1987 02/12/87 22.00 Yes
1010 5000 PPM Hypoactivity 03/05/1987 02/12/87 22.00 Yes