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Long-Term Study Individual Animal Clinical Observations

Study Information:

Chemical Name: beta-Myrcene
CASRN: ="123-35-3"
Study Number: C99023
Exposure Route: GAVAGE
TDMS Number: 9902304
Sex: Female
Strain and Species: B6C3F1 Mice

Animal Number Dose Group Clinical Observation Qualifier Incident Number Observation Date First Dose Date Days On Study Removal Observation
210 Vehicle Control Mass Torso/Lateral, Small (1mm-5mm) 1 09/24/2003 04/10/02 533.00 No
210 Vehicle Control Mass Torso/Lateral, Small (1mm-5mm) 1 10/22/2003 04/10/02 561.00 No
210 Vehicle Control Mass Torso/Lateral, Small (1mm-5mm) 1 11/19/2003 04/10/02 589.00 No
210 Vehicle Control Thin 12/17/2003 04/10/02 617.00 No
210 Vehicle Control Ulcer/Abscess Torso/Lateral 1 12/17/2003 04/10/02 617.00 No
210 Vehicle Control Mass Torso/Lateral, Large (16mm And Larger) 1 12/17/2003 04/10/02 617.00 No
210 Vehicle Control Mass Torso/Lateral, Large (16mm And Larger) 1 12/22/2003 04/10/02 622.00 Yes
210 Vehicle Control Ulcer/Abscess Torso/Lateral 1 12/22/2003 04/10/02 622.00 Yes
210 Vehicle Control Thin 12/22/2003 04/10/02 622.00 Yes
213 Vehicle Control Lethargic 03/02/2004 04/10/02 693.00 Yes
213 Vehicle Control Thin 03/02/2004 04/10/02 693.00 Yes
213 Vehicle Control Abnormal Breathing 03/02/2004 04/10/02 693.00 Yes
213 Vehicle Control Mass Torso/Lateral, Large (16mm And Larger) 1 03/02/2004 04/10/02 693.00 Yes
214 Vehicle Control Mass Torso/Dorsal, Large (16mm And Larger) 1 12/17/2003 04/10/02 617.00 No
214 Vehicle Control Mass Torso/Dorsal, Large (16mm And Larger) 1 12/22/2003 04/10/02 622.00 Yes
216 Vehicle Control Eye Abnormality 03/10/2004 04/10/02 701.00 No
216 Vehicle Control Eye Abnormality 03/15/2004 04/10/02 706.00 Yes
221 Vehicle Control Ruffled Fur 08/19/2003 04/10/02 497.00 Yes
221 Vehicle Control Lethargic 08/19/2003 04/10/02 497.00 Yes
229 Vehicle Control Abnormal Breathing 03/10/2004 04/10/02 701.00 No
229 Vehicle Control Abnormal Breathing 04/06/2004 04/10/02 728.00 Yes
251 0.25 G/KG Thin 03/26/2004 04/10/02 717.00 Yes
251 0.25 G/KG Ruffled Fur 03/26/2004 04/10/02 717.00 Yes
251 0.25 G/KG Lethargic 03/26/2004 04/10/02 717.00 Yes
252 0.25 G/KG Ulcer/Abscess Torso/Lateral 1 12/31/2003 04/10/02 631.00 Yes
256 0.25 G/KG Mass Torso/Lateral, Medium (6mm-15mm) 2 03/10/2004 04/10/02 701.00 No
256 0.25 G/KG Diarrhea 03/10/2004 04/10/02 701.00 No
256 0.25 G/KG Mass Torso/Lateral, Large (16mm And Larger) 2 03/25/2004 04/10/02 716.00 Yes
256 0.25 G/KG Thin 03/25/2004 04/10/02 716.00 Yes
256 0.25 G/KG Ruffled Fur 03/25/2004 04/10/02 716.00 Yes
258 0.25 G/KG Eye Abnormality 10/22/2003 04/10/02 561.00 No
258 0.25 G/KG Eye Abnormality 11/19/2003 04/10/02 589.00 No
261 0.25 G/KG Mass Torso/Ventral, Small (1mm-5mm) 1 03/10/2004 04/10/02 701.00 No
261 0.25 G/KG Abnormal Breathing 03/25/2004 04/10/02 716.00 Yes
261 0.25 G/KG Lethargic 03/25/2004 04/10/02 716.00 Yes
261 0.25 G/KG Thin 03/25/2004 04/10/02 716.00 Yes
261 0.25 G/KG Mass Torso/Dorsal, Medium (6mm-15mm) 1 03/25/2004 04/10/02 716.00 Yes
261 0.25 G/KG Mass Torso/Ventral, Medium (6mm-15mm) 2 03/25/2004 04/10/02 716.00 Yes
261 0.25 G/KG Ruffled Fur 03/25/2004 04/10/02 716.00 Yes
261 0.25 G/KG Ataxia 03/25/2004 04/10/02 716.00 Yes
271 0.25 G/KG Thin 09/23/2003 04/10/02 532.00 Yes
271 0.25 G/KG Ruffled Fur 09/23/2003 04/10/02 532.00 Yes
281 0.25 G/KG Abnormal Breathing 08/26/2002 04/10/02 139.00 Yes
281 0.25 G/KG Lethargic 08/26/2002 04/10/02 139.00 Yes
288 0.25 G/KG Abnormal Breathing 03/10/2004 04/10/02 701.00 No
288 0.25 G/KG Ruffled Fur 03/18/2004 04/10/02 709.00 Yes
288 0.25 G/KG Abnormal Breathing 03/18/2004 04/10/02 709.00 Yes
288 0.25 G/KG Thin 03/18/2004 04/10/02 709.00 Yes
301 0.5 G/KG Thin 02/05/2004 04/10/02 667.00 Yes
301 0.5 G/KG Lethargic 02/05/2004 04/10/02 667.00 Yes
304 0.5 G/KG Ulcer/Abscess Head 1 04/07/2004 04/10/02 729.00 Yes
305 0.5 G/KG Ulcer/Abscess Torso/Lateral 4 05/07/2003 04/10/02 393.00 No
305 0.5 G/KG Ulcer/Abscess Torso/Lateral 4 05/08/2003 04/10/02 394.00 Yes
306 0.5 G/KG Eye Abnormality 01/14/2004 04/10/02 645.00 No
306 0.5 G/KG Eye Abnormality 02/11/2004 04/10/02 673.00 No
306 0.5 G/KG Eye Abnormality 03/10/2004 04/10/02 701.00 No
306 0.5 G/KG Eye Abnormality 04/05/2004 04/10/02 727.00 Yes
308 0.5 G/KG Eye Abnormality 04/05/2004 04/10/02 727.00 Yes
315 0.5 G/KG Thin 12/15/2003 04/10/02 615.00 Yes
315 0.5 G/KG Lethargic 12/15/2003 04/10/02 615.00 Yes
315 0.5 G/KG Ulcer/Abscess Torso/Ventral 1 12/15/2003 04/10/02 615.00 Yes
322 0.5 G/KG Lethargic 10/10/2003 04/10/02 549.00 Yes
322 0.5 G/KG Thin 10/10/2003 04/10/02 549.00 Yes
328 0.5 G/KG Thin 07/24/2003 04/10/02 471.00 Yes
328 0.5 G/KG Lethargic 07/24/2003 04/10/02 471.00 Yes
333 0.5 G/KG Mass Torso/Ventral, Small (1mm-5mm) 1 10/22/2003 04/10/02 561.00 No
333 0.5 G/KG Mass Torso/Ventral, Small (1mm-5mm) 1 10/27/2003 04/10/02 566.00 Yes
337 0.5 G/KG Thin 01/14/2004 04/10/02 645.00 No
337 0.5 G/KG Ruffled Fur 02/12/2004 04/10/02 674.00 Yes
337 0.5 G/KG Abnormal Breathing 02/12/2004 04/10/02 674.00 Yes
337 0.5 G/KG Lethargic 02/12/2004 04/10/02 674.00 Yes
350 0.5 G/KG Thin 12/17/2003 04/10/02 617.00 No
350 0.5 G/KG Abnormal Breathing 12/17/2003 04/10/02 617.00 No
350 0.5 G/KG Ruffled Fur 12/17/2003 04/10/02 617.00 No
350 0.5 G/KG Lethargic 12/17/2003 04/10/02 617.00 No
350 0.5 G/KG Thin 12/19/2003 04/10/02 619.00 Yes
350 0.5 G/KG Lethargic 12/19/2003 04/10/02 619.00 Yes
359 1.0 G/KG Thin 09/24/2003 04/10/02 533.00 No
359 1.0 G/KG Thin 09/29/2003 04/10/02 538.00 Yes
361 1.0 G/KG Eye Abnormality 03/10/2004 04/10/02 701.00 No
361 1.0 G/KG Eye Abnormality 04/07/2004 04/10/02 729.00 Yes
370 1.0 G/KG Abnormal Breathing 01/28/2004 04/10/02 659.00 Yes
370 1.0 G/KG Mass Torso/Lateral, Medium (6mm-15mm) 1 01/28/2004 04/10/02 659.00 Yes
371 1.0 G/KG Ruffled Fur 07/21/2003 04/10/02 468.00 Yes
371 1.0 G/KG Lethargic 07/21/2003 04/10/02 468.00 Yes
371 1.0 G/KG Thin 07/21/2003 04/10/02 468.00 Yes
380 1.0 G/KG Abnormal Breathing 06/19/2003 04/10/02 436.00 Yes
380 1.0 G/KG Lethargic 06/19/2003 04/10/02 436.00 Yes
383 1.0 G/KG Abnormal Breathing 06/19/2003 04/10/02 436.00 Yes
383 1.0 G/KG Lethargic 06/19/2003 04/10/02 436.00 Yes
391 1.0 G/KG Lethargic 06/19/2003 04/10/02 436.00 Yes
391 1.0 G/KG Abnormal Breathing 06/19/2003 04/10/02 436.00 Yes
396 1.0 G/KG Ruffled Fur 06/19/2003 04/10/02 436.00 Yes