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Current Search Critera

Short-Term Study Individual Animal Clinical Observations

Study Information:

Chemical Name: o-Chloroaniline
CASRN: ="95-51-2"
Study Number: C91001
Exposure Route: GAVAGE
TDMS Number: 9100101
Sex: Female
Strain and Species: F 344/N Rats

Animal Number Dose Group Clinical Observation Qualifier Incident Number Observation Date First Dose Date Days On Study Removal Observation
61 Vehicle Control Nasal/Eye Discharge 03/17/1992 01/28/92 50.00 No
68 Vehicle Control Nasal/Eye Discharge 04/07/1992 01/28/92 71.00 No
68 Vehicle Control Nasal/Eye Discharge 04/14/1992 01/28/92 78.00 No
69 Vehicle Control Nasal/Eye Discharge 04/07/1992 01/28/92 71.00 No
69 Vehicle Control Nasal/Eye Discharge 04/14/1992 01/28/92 78.00 No
70 Vehicle Control Nasal/Eye Discharge 03/03/1992 01/28/92 36.00 No
70 Vehicle Control Nasal/Eye Discharge 03/10/1992 01/28/92 43.00 No
70 Vehicle Control Nasal/Eye Discharge 03/17/1992 01/28/92 50.00 No
71 10 MG/KG Nasal/Eye Discharge 04/21/1992 01/28/92 85.00 No
71 10 MG/KG Nasal/Eye Discharge 04/29/1992 01/28/92 93.00 Yes
73 10 MG/KG Nasal/Eye Discharge 03/03/1992 01/28/92 36.00 No
76 10 MG/KG Nasal/Eye Discharge 03/17/1992 01/28/92 50.00 No
76 10 MG/KG Nasal/Eye Discharge 03/24/1992 01/28/92 57.00 No
76 10 MG/KG Nasal/Eye Discharge 03/31/1992 01/28/92 64.00 No
79 10 MG/KG Abnormal Breathing 04/07/1992 01/28/92 71.00 No
88 20 MG/KG Nasal/Eye Discharge 04/07/1992 01/28/92 71.00 No
88 20 MG/KG Nasal/Eye Discharge 04/21/1992 01/28/92 85.00 No
92 40 MG/KG Nasal/Eye Discharge 03/24/1992 01/28/92 57.00 No
96 40 MG/KG Nasal/Eye Discharge 03/24/1992 01/28/92 57.00 No
99 40 MG/KG Tremors 04/29/1992 01/28/92 93.00 Yes
101 80 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
101 80 MG/KG Tremors 03/17/1992 01/28/92 50.00 No
101 80 MG/KG Tremors 03/31/1992 01/28/92 64.00 No
101 80 MG/KG Tremors 04/07/1992 01/28/92 71.00 No
101 80 MG/KG Tremors 04/14/1992 01/28/92 78.00 No
101 80 MG/KG Tremors 04/21/1992 01/28/92 85.00 No
102 80 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
102 80 MG/KG Nasal/Eye Discharge 02/18/1992 01/28/92 22.00 No
102 80 MG/KG Tremors 03/17/1992 01/28/92 50.00 No
102 80 MG/KG Tremors 03/31/1992 01/28/92 64.00 No
102 80 MG/KG Tremors 04/07/1992 01/28/92 71.00 No
102 80 MG/KG Tremors 04/14/1992 01/28/92 78.00 No
102 80 MG/KG Tremors 04/21/1992 01/28/92 85.00 No
102 80 MG/KG Abnormal Breathing 04/21/1992 01/28/92 85.00 No
103 80 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
103 80 MG/KG Tremors 03/17/1992 01/28/92 50.00 No
103 80 MG/KG Tremors 03/31/1992 01/28/92 64.00 No
103 80 MG/KG Tremors 04/07/1992 01/28/92 71.00 No
103 80 MG/KG Tremors 04/14/1992 01/28/92 78.00 No
103 80 MG/KG Tremors 04/21/1992 01/28/92 85.00 No
104 80 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
104 80 MG/KG Tremors 03/17/1992 01/28/92 50.00 No
104 80 MG/KG Tremors 03/31/1992 01/28/92 64.00 No
104 80 MG/KG Tremors 04/07/1992 01/28/92 71.00 No
104 80 MG/KG Tremors 04/14/1992 01/28/92 78.00 No
104 80 MG/KG Tremors 04/21/1992 01/28/92 85.00 No
104 80 MG/KG Nasal/Eye Discharge 04/29/1992 01/28/92 93.00 Yes
105 80 MG/KG Eye Abnormality 02/11/1992 01/28/92 15.00 No
105 80 MG/KG Eye Abnormality 02/18/1992 01/28/92 22.00 No
105 80 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
105 80 MG/KG Eye Abnormality 02/25/1992 01/28/92 29.00 No
105 80 MG/KG Eye Abnormality 03/03/1992 01/28/92 36.00 No
105 80 MG/KG Eye Abnormality 03/10/1992 01/28/92 43.00 No
105 80 MG/KG Tremors 03/17/1992 01/28/92 50.00 No
105 80 MG/KG Eye Abnormality 03/17/1992 01/28/92 50.00 No
105 80 MG/KG Eye Abnormality 03/24/1992 01/28/92 57.00 No
105 80 MG/KG Tremors 03/31/1992 01/28/92 64.00 No
105 80 MG/KG Eye Abnormality 03/31/1992 01/28/92 64.00 No
105 80 MG/KG Tremors 04/07/1992 01/28/92 71.00 No
105 80 MG/KG Eye Abnormality 04/07/1992 01/28/92 71.00 No
105 80 MG/KG Tremors 04/14/1992 01/28/92 78.00 No
105 80 MG/KG Eye Abnormality 04/14/1992 01/28/92 78.00 No
105 80 MG/KG Eye Abnormality 04/21/1992 01/28/92 85.00 No
105 80 MG/KG Tremors 04/21/1992 01/28/92 85.00 No
106 80 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
106 80 MG/KG Tremors 03/17/1992 01/28/92 50.00 No
106 80 MG/KG Tremors 03/31/1992 01/28/92 64.00 No
106 80 MG/KG Tremors 04/07/1992 01/28/92 71.00 No
106 80 MG/KG Tremors 04/14/1992 01/28/92 78.00 No
106 80 MG/KG Tremors 04/21/1992 01/28/92 85.00 No
107 80 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
107 80 MG/KG Tremors 03/17/1992 01/28/92 50.00 No
107 80 MG/KG Tremors 03/31/1992 01/28/92 64.00 No
107 80 MG/KG Tremors 04/07/1992 01/28/92 71.00 No
107 80 MG/KG Tremors 04/14/1992 01/28/92 78.00 No
107 80 MG/KG Tremors 04/21/1992 01/28/92 85.00 No
108 80 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
108 80 MG/KG Nasal/Eye Discharge 03/17/1992 01/28/92 50.00 No
108 80 MG/KG Tremors 03/17/1992 01/28/92 50.00 No
108 80 MG/KG Tremors 03/31/1992 01/28/92 64.00 No
108 80 MG/KG Tremors 04/07/1992 01/28/92 71.00 No
108 80 MG/KG Tremors 04/14/1992 01/28/92 78.00 No
108 80 MG/KG Tremors 04/21/1992 01/28/92 85.00 No
109 80 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
109 80 MG/KG Tremors 03/17/1992 01/28/92 50.00 No
109 80 MG/KG Tremors 03/31/1992 01/28/92 64.00 No
109 80 MG/KG Tremors 04/07/1992 01/28/92 71.00 No
109 80 MG/KG Tremors 04/14/1992 01/28/92 78.00 No
109 80 MG/KG Tremors 04/21/1992 01/28/92 85.00 No
110 80 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
110 80 MG/KG Tremors 03/17/1992 01/28/92 50.00 No
110 80 MG/KG Tremors 03/31/1992 01/28/92 64.00 No
110 80 MG/KG Tremors 04/07/1992 01/28/92 71.00 No
110 80 MG/KG Tremors 04/14/1992 01/28/92 78.00 No
110 80 MG/KG Tremors 04/21/1992 01/28/92 85.00 No
111 160 MG/KG Tremors 02/07/1992 01/28/92 11.00 No
111 160 MG/KG Thin 02/07/1992 01/28/92 11.00 No
111 160 MG/KG Tremors 02/11/1992 01/28/92 15.00 No
111 160 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
111 160 MG/KG Tremors 03/03/1992 01/28/92 36.00 No
111 160 MG/KG Tremors 03/10/1992 01/28/92 43.00 No
111 160 MG/KG Tremors 03/17/1992 01/28/92 50.00 No
111 160 MG/KG Tremors 03/31/1992 01/28/92 64.00 No
111 160 MG/KG Tremors 04/07/1992 01/28/92 71.00 No
111 160 MG/KG Tremors 04/14/1992 01/28/92 78.00 No
111 160 MG/KG Tremors 04/21/1992 01/28/92 85.00 No
111 160 MG/KG Tremors 04/29/1992 01/28/92 93.00 Yes
112 160 MG/KG Thin 02/07/1992 01/28/92 11.00 No
112 160 MG/KG Tremors 02/07/1992 01/28/92 11.00 No
112 160 MG/KG Tremors 02/11/1992 01/28/92 15.00 No
112 160 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
112 160 MG/KG Tremors 03/10/1992 01/28/92 43.00 No
112 160 MG/KG Tremors 03/17/1992 01/28/92 50.00 No
112 160 MG/KG Abnormal Breathing 03/24/1992 01/28/92 57.00 No
112 160 MG/KG Tremors 03/31/1992 01/28/92 64.00 No
112 160 MG/KG Tremors 04/07/1992 01/28/92 71.00 No
112 160 MG/KG Tremors 04/14/1992 01/28/92 78.00 No
112 160 MG/KG Tremors 04/21/1992 01/28/92 85.00 No
112 160 MG/KG Tremors 04/29/1992 01/28/92 93.00 Yes
112 160 MG/KG Abnormal Breathing 04/29/1992 01/28/92 93.00 Yes
113 160 MG/KG Tremors 02/07/1992 01/28/92 11.00 No
113 160 MG/KG Thin 02/07/1992 01/28/92 11.00 No
113 160 MG/KG Tremors 02/11/1992 01/28/92 15.00 No
113 160 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
113 160 MG/KG Tremors 03/03/1992 01/28/92 36.00 No
113 160 MG/KG Tremors 03/10/1992 01/28/92 43.00 No
113 160 MG/KG Tremors 03/17/1992 01/28/92 50.00 No
113 160 MG/KG Tremors 03/31/1992 01/28/92 64.00 No
113 160 MG/KG Tremors 04/07/1992 01/28/92 71.00 No
113 160 MG/KG Tremors 04/14/1992 01/28/92 78.00 No
113 160 MG/KG Tremors 04/21/1992 01/28/92 85.00 No
114 160 MG/KG Thin 02/07/1992 01/28/92 11.00 No
114 160 MG/KG Tremors 02/07/1992 01/28/92 11.00 No
114 160 MG/KG Tremors 02/11/1992 01/28/92 15.00 No
114 160 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
114 160 MG/KG Tremors 03/03/1992 01/28/92 36.00 No
114 160 MG/KG Tremors 03/10/1992 01/28/92 43.00 No
114 160 MG/KG Tremors 03/17/1992 01/28/92 50.00 No
114 160 MG/KG Tremors 03/31/1992 01/28/92 64.00 No
114 160 MG/KG Tremors 04/07/1992 01/28/92 71.00 No
114 160 MG/KG Tremors 04/14/1992 01/28/92 78.00 No
114 160 MG/KG Tremors 04/21/1992 01/28/92 85.00 No
114 160 MG/KG Tremors 04/29/1992 01/28/92 93.00 Yes
115 160 MG/KG Tremors 02/07/1992 01/28/92 11.00 No
115 160 MG/KG Thin 02/07/1992 01/28/92 11.00 No
115 160 MG/KG Tremors 02/11/1992 01/28/92 15.00 No
115 160 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
115 160 MG/KG Tremors 03/03/1992 01/28/92 36.00 No
115 160 MG/KG Tremors 03/10/1992 01/28/92 43.00 No
115 160 MG/KG Tremors 03/17/1992 01/28/92 50.00 No
115 160 MG/KG Tremors 03/31/1992 01/28/92 64.00 No
115 160 MG/KG Tremors 04/07/1992 01/28/92 71.00 No
115 160 MG/KG Tremors 04/14/1992 01/28/92 78.00 No
115 160 MG/KG Tremors 04/21/1992 01/28/92 85.00 No
115 160 MG/KG Tremors 04/29/1992 01/28/92 93.00 Yes
116 160 MG/KG Thin 02/07/1992 01/28/92 11.00 No
116 160 MG/KG Tremors 02/07/1992 01/28/92 11.00 No
116 160 MG/KG Tremors 02/11/1992 01/28/92 15.00 No
116 160 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
116 160 MG/KG Tremors 02/25/1992 01/28/92 29.00 No
116 160 MG/KG Tremors 03/03/1992 01/28/92 36.00 No
116 160 MG/KG Tremors 03/10/1992 01/28/92 43.00 No
116 160 MG/KG Tremors 03/17/1992 01/28/92 50.00 No
116 160 MG/KG Tremors 03/31/1992 01/28/92 64.00 No
116 160 MG/KG Tremors 04/07/1992 01/28/92 71.00 No
116 160 MG/KG Tremors 04/14/1992 01/28/92 78.00 No
116 160 MG/KG Tremors 04/21/1992 01/28/92 85.00 No
116 160 MG/KG Tremors 04/29/1992 01/28/92 93.00 Yes
117 160 MG/KG Thin 02/07/1992 01/28/92 11.00 No
117 160 MG/KG Tremors 02/07/1992 01/28/92 11.00 No
117 160 MG/KG Tremors 02/11/1992 01/28/92 15.00 No
117 160 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
117 160 MG/KG Tremors 03/03/1992 01/28/92 36.00 No
117 160 MG/KG Tremors 03/10/1992 01/28/92 43.00 No
117 160 MG/KG Tremors 03/17/1992 01/28/92 50.00 No
117 160 MG/KG Tremors 03/31/1992 01/28/92 64.00 No
117 160 MG/KG Tremors 04/07/1992 01/28/92 71.00 No
117 160 MG/KG Tremors 04/14/1992 01/28/92 78.00 No
117 160 MG/KG Tremors 04/21/1992 01/28/92 85.00 No
117 160 MG/KG Tremors 04/29/1992 01/28/92 93.00 Yes
118 160 MG/KG Thin 02/07/1992 01/28/92 11.00 No
118 160 MG/KG Tremors 02/07/1992 01/28/92 11.00 No
118 160 MG/KG Tremors 02/11/1992 01/28/92 15.00 No
118 160 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
118 160 MG/KG Tremors 03/10/1992 01/28/92 43.00 No
118 160 MG/KG Tremors 03/17/1992 01/28/92 50.00 No
118 160 MG/KG Tremors 03/31/1992 01/28/92 64.00 No
118 160 MG/KG Tremors 04/07/1992 01/28/92 71.00 No
118 160 MG/KG Tremors 04/14/1992 01/28/92 78.00 No
118 160 MG/KG Tremors 04/21/1992 01/28/92 85.00 No
118 160 MG/KG Tremors 04/29/1992 01/28/92 93.00 Yes
119 160 MG/KG Thin 02/07/1992 01/28/92 11.00 No
119 160 MG/KG Tremors 02/07/1992 01/28/92 11.00 No
119 160 MG/KG Tremors 02/11/1992 01/28/92 15.00 No
119 160 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
119 160 MG/KG Nasal/Eye Discharge 03/03/1992 01/28/92 36.00 No
119 160 MG/KG Tremors 03/10/1992 01/28/92 43.00 No
119 160 MG/KG Tremors 03/17/1992 01/28/92 50.00 No
119 160 MG/KG Tremors 03/31/1992 01/28/92 64.00 No
119 160 MG/KG Tremors 04/07/1992 01/28/92 71.00 No
119 160 MG/KG Tremors 04/14/1992 01/28/92 78.00 No
119 160 MG/KG Tremors 04/21/1992 01/28/92 85.00 No
119 160 MG/KG Tremors 04/29/1992 01/28/92 93.00 Yes
120 160 MG/KG Thin 02/07/1992 01/28/92 11.00 No
120 160 MG/KG Tremors 02/07/1992 01/28/92 11.00 No
120 160 MG/KG Tremors 02/11/1992 01/28/92 15.00 No
120 160 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
120 160 MG/KG Tremors 03/10/1992 01/28/92 43.00 No
120 160 MG/KG Tremors 03/17/1992 01/28/92 50.00 No
120 160 MG/KG Nasal/Eye Discharge 03/24/1992 01/28/92 57.00 No
120 160 MG/KG Tremors 03/24/1992 01/28/92 57.00 No
120 160 MG/KG Tremors 03/31/1992 01/28/92 64.00 No
120 160 MG/KG Nasal/Eye Discharge 03/31/1992 01/28/92 64.00 No
120 160 MG/KG Tremors 04/07/1992 01/28/92 71.00 No
120 160 MG/KG Tremors 04/14/1992 01/28/92 78.00 No
120 160 MG/KG Tremors 04/21/1992 01/28/92 85.00 No
120 160 MG/KG Tremors 04/29/1992 01/28/92 93.00 Yes
221 80 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
222 80 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
223 80 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
224 80 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
225 80 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
226 80 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
227 80 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
228 80 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
229 80 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
230 80 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
231 160 MG/KG Thin 02/07/1992 01/28/92 11.00 No
231 160 MG/KG Tremors 02/07/1992 01/28/92 11.00 No
231 160 MG/KG Tremors 02/11/1992 01/28/92 15.00 No
231 160 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
232 160 MG/KG Tremors 02/07/1992 01/28/92 11.00 No
232 160 MG/KG Thin 02/07/1992 01/28/92 11.00 No
232 160 MG/KG Tremors 02/11/1992 01/28/92 15.00 No
232 160 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
233 160 MG/KG Tremors 02/07/1992 01/28/92 11.00 No
233 160 MG/KG Thin 02/07/1992 01/28/92 11.00 No
233 160 MG/KG Tremors 02/11/1992 01/28/92 15.00 No
233 160 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
234 160 MG/KG Thin 02/07/1992 01/28/92 11.00 No
234 160 MG/KG Tremors 02/07/1992 01/28/92 11.00 No
234 160 MG/KG Tremors 02/11/1992 01/28/92 15.00 No
234 160 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
235 160 MG/KG Thin 02/07/1992 01/28/92 11.00 No
235 160 MG/KG Tremors 02/07/1992 01/28/92 11.00 No
235 160 MG/KG Tremors 02/11/1992 01/28/92 15.00 No
235 160 MG/KG Tremors 02/18/1992 01/28/92 22.00 No
236 160 MG/KG Tremors 02/07/1992 01/28/92 11.00 No
236 160 MG/KG Thin 02/07/1992 01/28/92 11.00 No
236 160 MG/KG Tremors 02/11/1992 01/28/92 15.00 No
237 160 MG/KG Thin 02/07/1992 01/28/92 11.00 No
237 160 MG/KG Tremors 02/07/1992 01/28/92 11.00 No
237 160 MG/KG Tremors 02/11/1992 01/28/92 15.00 No
238 160 MG/KG Tremors 02/07/1992 01/28/92 11.00 No
238 160 MG/KG Thin 02/07/1992 01/28/92 11.00 No
238 160 MG/KG Tremors 02/11/1992 01/28/92 15.00 No
239 160 MG/KG Tremors 02/07/1992 01/28/92 11.00 No
239 160 MG/KG Thin 02/07/1992 01/28/92 11.00 No
239 160 MG/KG Tremors 02/11/1992 01/28/92 15.00 No
240 160 MG/KG Thin 02/07/1992 01/28/92 11.00 No
240 160 MG/KG Tremors 02/07/1992 01/28/92 11.00 No
240 160 MG/KG Tremors 02/11/1992 01/28/92 15.00 No