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Current Search Critera

Short-Term Study Individual Animal Clinical Observations

Study Information:

Chemical Name: o-Chloroaniline
CASRN: ="95-51-2"
Study Number: C91001
Exposure Route: GAVAGE
TDMS Number: 9100101
Sex: Male
Strain and Species: F 344/N Rats

Animal Number Dose Group Clinical Observation Qualifier Incident Number Observation Date First Dose Date Days On Study Removal Observation
1 Vehicle Control Nasal/Eye Discharge 03/16/1992 01/27/92 50.00 No
1 Vehicle Control Nasal/Eye Discharge 03/23/1992 01/27/92 57.00 No
7 Vehicle Control Eye Abnormality 03/02/1992 01/27/92 36.00 No
7 Vehicle Control Eye Abnormality 03/09/1992 01/27/92 43.00 No
7 Vehicle Control Eye Abnormality 03/16/1992 01/27/92 50.00 No
7 Vehicle Control Eye Abnormality 03/23/1992 01/27/92 57.00 No
7 Vehicle Control Eye Abnormality 03/30/1992 01/27/92 64.00 No
7 Vehicle Control Eye Abnormality 04/06/1992 01/27/92 71.00 No
7 Vehicle Control Eye Abnormality 04/13/1992 01/27/92 78.00 No
7 Vehicle Control Eye Abnormality 04/20/1992 01/27/92 85.00 No
10 Vehicle Control Nasal/Eye Discharge 03/09/1992 01/27/92 43.00 No
11 10 MG/KG Nasal/Eye Discharge 03/30/1992 01/27/92 64.00 No
11 10 MG/KG Nasal/Eye Discharge 04/13/1992 01/27/92 78.00 No
13 10 MG/KG Nasal/Eye Discharge 04/13/1992 01/27/92 78.00 No
15 10 MG/KG Nasal/Eye Discharge 03/02/1992 01/27/92 36.00 No
15 10 MG/KG Nasal/Eye Discharge 03/09/1992 01/27/92 43.00 No
16 10 MG/KG Nasal/Eye Discharge 03/09/1992 01/27/92 43.00 No
16 10 MG/KG Nasal/Eye Discharge 03/30/1992 01/27/92 64.00 No
18 10 MG/KG Nasal/Eye Discharge 03/16/1992 01/27/92 50.00 No
22 20 MG/KG Nasal/Eye Discharge 04/06/1992 01/27/92 71.00 No
23 20 MG/KG Nasal/Eye Discharge 04/06/1992 01/27/92 71.00 No
30 20 MG/KG Eye Abnormality 03/30/1992 01/27/92 64.00 No
30 20 MG/KG Nasal/Eye Discharge 04/06/1992 01/27/92 71.00 No
30 20 MG/KG Eye Abnormality 04/06/1992 01/27/92 71.00 No
30 20 MG/KG Nasal/Eye Discharge 04/13/1992 01/27/92 78.00 No
30 20 MG/KG Eye Abnormality 04/13/1992 01/27/92 78.00 No
30 20 MG/KG Eye Abnormality 04/20/1992 01/27/92 85.00 No
30 20 MG/KG Nasal/Eye Discharge 04/20/1992 01/27/92 85.00 No
31 40 MG/KG Nasal/Eye Discharge 03/23/1992 01/27/92 57.00 No
31 40 MG/KG Nasal/Eye Discharge 04/13/1992 01/27/92 78.00 No
31 40 MG/KG Nasal/Eye Discharge 04/20/1992 01/27/92 85.00 No
38 40 MG/KG Tremors 03/30/1992 01/27/92 64.00 No
41 80 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
41 80 MG/KG Tremors 03/16/1992 01/27/92 50.00 No
41 80 MG/KG Tremors 03/23/1992 01/27/92 57.00 No
41 80 MG/KG Tremors 03/30/1992 01/27/92 64.00 No
41 80 MG/KG Tremors 04/06/1992 01/27/92 71.00 No
41 80 MG/KG Tremors 04/13/1992 01/27/92 78.00 No
41 80 MG/KG Tremors 04/20/1992 01/27/92 85.00 No
41 80 MG/KG Tremors 04/28/1992 01/27/92 93.00 Yes
42 80 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
42 80 MG/KG Tremors 03/16/1992 01/27/92 50.00 No
42 80 MG/KG Tremors 03/23/1992 01/27/92 57.00 No
42 80 MG/KG Tremors 03/30/1992 01/27/92 64.00 No
42 80 MG/KG Tremors 04/06/1992 01/27/92 71.00 No
42 80 MG/KG Tremors 04/13/1992 01/27/92 78.00 No
42 80 MG/KG Tremors 04/20/1992 01/27/92 85.00 No
42 80 MG/KG Tremors 04/28/1992 01/27/92 93.00 Yes
43 80 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
43 80 MG/KG Tremors 03/16/1992 01/27/92 50.00 No
43 80 MG/KG Tremors 03/23/1992 01/27/92 57.00 No
43 80 MG/KG Tremors 03/30/1992 01/27/92 64.00 No
43 80 MG/KG Tremors 04/06/1992 01/27/92 71.00 No
43 80 MG/KG Tremors 04/13/1992 01/27/92 78.00 No
43 80 MG/KG Tremors 04/20/1992 01/27/92 85.00 No
43 80 MG/KG Tremors 04/28/1992 01/27/92 93.00 Yes
44 80 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
44 80 MG/KG Tremors 03/16/1992 01/27/92 50.00 No
44 80 MG/KG Tremors 03/23/1992 01/27/92 57.00 No
44 80 MG/KG Tremors 03/30/1992 01/27/92 64.00 No
44 80 MG/KG Tremors 04/06/1992 01/27/92 71.00 No
44 80 MG/KG Tremors 04/13/1992 01/27/92 78.00 No
44 80 MG/KG Tremors 04/20/1992 01/27/92 85.00 No
44 80 MG/KG Tremors 04/28/1992 01/27/92 93.00 Yes
45 80 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
45 80 MG/KG Tremors 03/16/1992 01/27/92 50.00 No
45 80 MG/KG Tremors 03/23/1992 01/27/92 57.00 No
45 80 MG/KG Tremors 03/30/1992 01/27/92 64.00 No
45 80 MG/KG Tremors 04/06/1992 01/27/92 71.00 No
45 80 MG/KG Tremors 04/13/1992 01/27/92 78.00 No
45 80 MG/KG Nasal/Eye Discharge 04/13/1992 01/27/92 78.00 No
45 80 MG/KG Tremors 04/20/1992 01/27/92 85.00 No
45 80 MG/KG Tremors 04/28/1992 01/27/92 93.00 Yes
46 80 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
46 80 MG/KG Tremors 03/16/1992 01/27/92 50.00 No
46 80 MG/KG Tremors 03/23/1992 01/27/92 57.00 No
46 80 MG/KG Tremors 03/30/1992 01/27/92 64.00 No
46 80 MG/KG Tremors 04/06/1992 01/27/92 71.00 No
46 80 MG/KG Tremors 04/13/1992 01/27/92 78.00 No
46 80 MG/KG Tremors 04/20/1992 01/27/92 85.00 No
46 80 MG/KG Tremors 04/28/1992 01/27/92 93.00 Yes
47 80 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
47 80 MG/KG Tremors 03/16/1992 01/27/92 50.00 No
47 80 MG/KG Tremors 03/23/1992 01/27/92 57.00 No
47 80 MG/KG Tremors 03/30/1992 01/27/92 64.00 No
47 80 MG/KG Tremors 04/06/1992 01/27/92 71.00 No
47 80 MG/KG Nasal/Eye Discharge 04/13/1992 01/27/92 78.00 No
47 80 MG/KG Tremors 04/13/1992 01/27/92 78.00 No
47 80 MG/KG Tremors 04/20/1992 01/27/92 85.00 No
47 80 MG/KG Tremors 04/28/1992 01/27/92 93.00 Yes
48 80 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
48 80 MG/KG Tremors 03/16/1992 01/27/92 50.00 No
48 80 MG/KG Tremors 03/23/1992 01/27/92 57.00 No
48 80 MG/KG Tremors 03/30/1992 01/27/92 64.00 No
48 80 MG/KG Tremors 04/06/1992 01/27/92 71.00 No
48 80 MG/KG Tremors 04/13/1992 01/27/92 78.00 No
48 80 MG/KG Tremors 04/20/1992 01/27/92 85.00 No
48 80 MG/KG Tremors 04/28/1992 01/27/92 93.00 Yes
49 80 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
49 80 MG/KG Tremors 03/16/1992 01/27/92 50.00 No
49 80 MG/KG Tremors 03/23/1992 01/27/92 57.00 No
49 80 MG/KG Tremors 03/30/1992 01/27/92 64.00 No
49 80 MG/KG Tremors 04/06/1992 01/27/92 71.00 No
49 80 MG/KG Tremors 04/13/1992 01/27/92 78.00 No
49 80 MG/KG Tremors 04/20/1992 01/27/92 85.00 No
49 80 MG/KG Tremors 04/28/1992 01/27/92 93.00 Yes
50 80 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
50 80 MG/KG Tremors 03/16/1992 01/27/92 50.00 No
50 80 MG/KG Tremors 03/23/1992 01/27/92 57.00 No
50 80 MG/KG Tremors 03/30/1992 01/27/92 64.00 No
50 80 MG/KG Tremors 04/06/1992 01/27/92 71.00 No
50 80 MG/KG Tremors 04/13/1992 01/27/92 78.00 No
50 80 MG/KG Tremors 04/20/1992 01/27/92 85.00 No
50 80 MG/KG Tremors 04/28/1992 01/27/92 93.00 Yes
51 160 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
51 160 MG/KG Nasal/Eye Discharge 02/24/1992 01/27/92 29.00 No
51 160 MG/KG Tremors 03/02/1992 01/27/92 36.00 No
51 160 MG/KG Tremors 03/09/1992 01/27/92 43.00 No
51 160 MG/KG Tremors 03/16/1992 01/27/92 50.00 No
51 160 MG/KG Tremors 03/23/1992 01/27/92 57.00 No
51 160 MG/KG Tremors 03/30/1992 01/27/92 64.00 No
51 160 MG/KG Tremors 04/06/1992 01/27/92 71.00 No
51 160 MG/KG Nasal/Eye Discharge 04/13/1992 01/27/92 78.00 No
51 160 MG/KG Tremors 04/13/1992 01/27/92 78.00 No
51 160 MG/KG Tremors 04/20/1992 01/27/92 85.00 No
51 160 MG/KG Tremors 04/28/1992 01/27/92 93.00 Yes
52 160 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
52 160 MG/KG Tremors 02/24/1992 01/27/92 29.00 No
52 160 MG/KG Tremors 03/02/1992 01/27/92 36.00 No
52 160 MG/KG Tremors 03/09/1992 01/27/92 43.00 No
52 160 MG/KG Tremors 03/16/1992 01/27/92 50.00 No
52 160 MG/KG Tremors 03/23/1992 01/27/92 57.00 No
52 160 MG/KG Tremors 03/30/1992 01/27/92 64.00 No
52 160 MG/KG Tremors 04/06/1992 01/27/92 71.00 No
52 160 MG/KG Tremors 04/13/1992 01/27/92 78.00 No
52 160 MG/KG Tremors 04/20/1992 01/27/92 85.00 No
52 160 MG/KG Tremors 04/28/1992 01/27/92 93.00 Yes
53 160 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
53 160 MG/KG Tremors 03/09/1992 01/27/92 43.00 No
53 160 MG/KG Tremors 03/16/1992 01/27/92 50.00 No
53 160 MG/KG Tremors 03/23/1992 01/27/92 57.00 No
53 160 MG/KG Tremors 03/30/1992 01/27/92 64.00 No
53 160 MG/KG Tremors 04/06/1992 01/27/92 71.00 No
53 160 MG/KG Tremors 04/13/1992 01/27/92 78.00 No
53 160 MG/KG Tremors 04/20/1992 01/27/92 85.00 No
53 160 MG/KG Tremors 04/28/1992 01/27/92 93.00 Yes
54 160 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
54 160 MG/KG Tremors 03/16/1992 01/27/92 50.00 No
54 160 MG/KG Tremors 03/23/1992 01/27/92 57.00 No
54 160 MG/KG Tremors 03/30/1992 01/27/92 64.00 No
54 160 MG/KG Tremors 04/06/1992 01/27/92 71.00 No
54 160 MG/KG Tremors 04/13/1992 01/27/92 78.00 No
54 160 MG/KG Tremors 04/20/1992 01/27/92 85.00 No
54 160 MG/KG Tremors 04/28/1992 01/27/92 93.00 Yes
55 160 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
55 160 MG/KG Tremors 03/16/1992 01/27/92 50.00 No
55 160 MG/KG Tremors 03/23/1992 01/27/92 57.00 No
55 160 MG/KG Tremors 03/30/1992 01/27/92 64.00 No
55 160 MG/KG Tremors 04/06/1992 01/27/92 71.00 No
55 160 MG/KG Tremors 04/13/1992 01/27/92 78.00 No
55 160 MG/KG Tremors 04/20/1992 01/27/92 85.00 No
55 160 MG/KG Tremors 04/28/1992 01/27/92 93.00 Yes
56 160 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
56 160 MG/KG Tremors 03/16/1992 01/27/92 50.00 No
56 160 MG/KG Tremors 03/23/1992 01/27/92 57.00 No
56 160 MG/KG Tremors 03/30/1992 01/27/92 64.00 No
56 160 MG/KG Tremors 04/06/1992 01/27/92 71.00 No
56 160 MG/KG Tremors 04/13/1992 01/27/92 78.00 No
56 160 MG/KG Tremors 04/20/1992 01/27/92 85.00 No
56 160 MG/KG Tremors 04/28/1992 01/27/92 93.00 Yes
57 160 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
57 160 MG/KG Tremors 03/02/1992 01/27/92 36.00 No
57 160 MG/KG Tremors 03/16/1992 01/27/92 50.00 No
57 160 MG/KG Tremors 03/23/1992 01/27/92 57.00 No
57 160 MG/KG Tremors 03/30/1992 01/27/92 64.00 No
57 160 MG/KG Tremors 04/06/1992 01/27/92 71.00 No
57 160 MG/KG Tremors 04/13/1992 01/27/92 78.00 No
57 160 MG/KG Tremors 04/20/1992 01/27/92 85.00 No
57 160 MG/KG Tremors 04/28/1992 01/27/92 93.00 Yes
58 160 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
58 160 MG/KG Tremors 03/16/1992 01/27/92 50.00 No
58 160 MG/KG Tremors 03/23/1992 01/27/92 57.00 No
58 160 MG/KG Tremors 03/30/1992 01/27/92 64.00 No
58 160 MG/KG Tremors 04/06/1992 01/27/92 71.00 No
58 160 MG/KG Tremors 04/13/1992 01/27/92 78.00 No
58 160 MG/KG Tremors 04/20/1992 01/27/92 85.00 No
58 160 MG/KG Tremors 04/28/1992 01/27/92 93.00 Yes
59 160 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
59 160 MG/KG Tremors 03/16/1992 01/27/92 50.00 No
59 160 MG/KG Tremors 03/23/1992 01/27/92 57.00 No
59 160 MG/KG Tremors 03/30/1992 01/27/92 64.00 No
59 160 MG/KG Tremors 04/06/1992 01/27/92 71.00 No
59 160 MG/KG Tremors 04/13/1992 01/27/92 78.00 No
59 160 MG/KG Tremors 04/20/1992 01/27/92 85.00 No
59 160 MG/KG Tremors 04/28/1992 01/27/92 93.00 Yes
60 160 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
60 160 MG/KG Tremors 03/16/1992 01/27/92 50.00 No
60 160 MG/KG Tremors 03/23/1992 01/27/92 57.00 No
60 160 MG/KG Tremors 03/30/1992 01/27/92 64.00 No
60 160 MG/KG Tremors 04/06/1992 01/27/92 71.00 No
60 160 MG/KG Tremors 04/13/1992 01/27/92 78.00 No
60 160 MG/KG Abnormal Breathing 04/13/1992 01/27/92 78.00 No
60 160 MG/KG Tremors 04/20/1992 01/27/92 85.00 No
60 160 MG/KG Abnormal Breathing 04/20/1992 01/27/92 85.00 No
60 160 MG/KG Tremors 04/28/1992 01/27/92 93.00 Yes
143 20 MG/KG Eye Abnormality 02/03/1992 01/27/92 8.00 No
143 20 MG/KG Eye Abnormality 02/10/1992 01/27/92 15.00 No
143 20 MG/KG Eye Abnormality 02/18/1992 01/27/92 23.00 Yes
161 80 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
161 80 MG/KG Tremors 02/18/1992 01/27/92 23.00 Yes
162 80 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
162 80 MG/KG Tremors 02/18/1992 01/27/92 23.00 Yes
163 80 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
163 80 MG/KG Tremors 02/18/1992 01/27/92 23.00 Yes
164 80 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
164 80 MG/KG Tremors 02/18/1992 01/27/92 23.00 Yes
165 80 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
165 80 MG/KG Tremors 02/18/1992 01/27/92 23.00 Yes
166 80 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
166 80 MG/KG Tremors 02/18/1992 01/27/92 23.00 Yes
167 80 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
167 80 MG/KG Tremors 02/18/1992 01/27/92 23.00 Yes
168 80 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
168 80 MG/KG Tremors 02/18/1992 01/27/92 23.00 Yes
169 80 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
169 80 MG/KG Tremors 02/18/1992 01/27/92 23.00 Yes
170 80 MG/KG Eye Abnormality 02/03/1992 01/27/92 8.00 No
170 80 MG/KG Eye Abnormality 02/10/1992 01/27/92 15.00 No
170 80 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
170 80 MG/KG Eye Abnormality 02/17/1992 01/27/92 22.00 No
170 80 MG/KG Tremors 02/18/1992 01/27/92 23.00 Yes
171 160 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
171 160 MG/KG Tremors 02/18/1992 01/27/92 23.00 Yes
172 160 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
172 160 MG/KG Tremors 02/18/1992 01/27/92 23.00 Yes
173 160 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
173 160 MG/KG Tremors 02/18/1992 01/27/92 23.00 Yes
174 160 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
174 160 MG/KG Tremors 02/18/1992 01/27/92 23.00 Yes
175 160 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
175 160 MG/KG Tremors 02/18/1992 01/27/92 23.00 Yes
176 160 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
176 160 MG/KG Tremors 02/18/1992 01/27/92 23.00 Yes
177 160 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
177 160 MG/KG Tremors 02/18/1992 01/27/92 23.00 Yes
178 160 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
178 160 MG/KG Tremors 02/18/1992 01/27/92 23.00 Yes
179 160 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
179 160 MG/KG Tremors 02/18/1992 01/27/92 23.00 Yes
180 160 MG/KG Tremors 02/17/1992 01/27/92 22.00 No
180 160 MG/KG Tremors 02/18/1992 01/27/92 23.00 Yes