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Short-Term Study Individual Animal Clinical Observations

Study Information:

Chemical Name: tert-Butyl alcohol
CASRN: ="75-65-0"
Study Number: C55367B
Exposure Route: DOSED WATER
TDMS Number: 0514202
Sex: Male
Strain and Species: B6C3F1 Mice

Animal Number Dose Group Clinical Observation Qualifier Incident Number Observation Date First Dose Date Days On Study Removal Observation
1 Vehicle Control Ruffled Fur 01/27/1986 12/10/85 49.00 No
1 Vehicle Control Discoloration Tail, White 02/24/1986 12/10/85 77.00 No
1 Vehicle Control Discoloration Tail, White 03/03/1986 12/10/85 84.00 No
1 Vehicle Control Discoloration Tail, White 03/10/1986 12/10/85 91.00 No
2 Vehicle Control Ruffled Fur 01/27/1986 12/10/85 49.00 No
3 Vehicle Control Ruffled Fur 01/27/1986 12/10/85 49.00 No
4 Vehicle Control Ruffled Fur 01/27/1986 12/10/85 49.00 No
8 Vehicle Control Ruffled Fur 01/27/1986 12/10/85 49.00 No
16 0.25 % Alopecia 12/30/1985 12/10/85 21.00 No
20 0.25 % Alopecia 12/30/1985 12/10/85 21.00 No
20 0.25 % Alopecia 01/13/1986 12/10/85 35.00 No
20 0.25 % Alopecia 01/20/1986 12/10/85 42.00 No
20 0.25 % Alopecia 01/27/1986 12/10/85 49.00 No
20 0.25 % Alopecia 02/03/1986 12/10/85 56.00 No
20 0.25 % Alopecia 02/10/1986 12/10/85 63.00 No
20 0.25 % Alopecia 02/17/1986 12/10/85 70.00 No
20 0.25 % Alopecia 02/24/1986 12/10/85 77.00 No
20 0.25 % Alopecia 03/03/1986 12/10/85 84.00 No
20 0.25 % Alopecia 03/10/1986 12/10/85 91.00 No
20 0.25 % Alopecia 03/15/1986 12/10/85 96.00 Yes
21 0.5 % Ruffled Fur 01/27/1986 12/10/85 49.00 No
27 0.5 % Ruffled Fur 01/27/1986 12/10/85 49.00 No
30 0.5 % Alopecia 12/10/1985 12/10/85 1.00 No
31 1.0 % Ruffled Fur 01/27/1986 12/10/85 49.00 No
33 1.0 % Ruffled Fur 01/27/1986 12/10/85 49.00 No
36 1.0 % Hypoactivity 01/27/1986 12/10/85 49.00 No
40 1.0 % Ruffled Fur 01/27/1986 12/10/85 49.00 No
41 2.0 % Emaciated 01/20/1986 12/10/85 42.00 No
42 2.0 % Ruffled Fur 01/27/1986 12/10/85 49.00 No
43 2.0 % Ruffled Fur 01/27/1986 12/10/85 49.00 No
46 2.0 % Ruffled Fur 01/27/1986 12/10/85 49.00 No
50 2.0 % Urine Stain Yellow 01/27/1986 12/10/85 49.00 No
50 2.0 % Ruffled Fur 01/27/1986 12/10/85 49.00 No
50 2.0 % Alopecia 02/03/1986 12/10/85 56.00 No
51 4.0 % Ruffled Fur 01/27/1986 12/10/85 49.00 No
53 4.0 % Emaciated 01/06/1986 12/10/85 28.00 Yes
53 4.0 % Dyspnea 01/06/1986 12/10/85 28.00 Yes
53 4.0 % Dyspnea 01/06/1986 12/10/85 28.00 No
53 4.0 % Hypoactivity 01/06/1986 12/10/85 28.00 Yes
53 4.0 % Tremors 01/06/1986 12/10/85 28.00 No
53 4.0 % Abnormal Posture 01/06/1986 12/10/85 28.00 No
53 4.0 % Tremors 01/06/1986 12/10/85 28.00 Yes
53 4.0 % Hypothermia 01/06/1986 12/10/85 28.00 Yes
54 4.0 % Micro-Ophthalmia 02/09/1986 12/10/85 62.00 Yes
54 4.0 % Emaciated 02/09/1986 12/10/85 62.00 Yes
54 4.0 % Hypoactivity 02/09/1986 12/10/85 62.00 Yes
54 4.0 % Ruffled Fur 02/09/1986 12/10/85 62.00 Yes
54 4.0 % Head Tilted 02/09/1986 12/10/85 62.00 Yes
54 4.0 % Ataxia 02/09/1986 12/10/85 62.00 Yes
54 4.0 % Urine Stain Yellow 02/09/1986 12/10/85 62.00 Yes
58 4.0 % Ruffled Fur 01/27/1986 12/10/85 49.00 No
59 4.0 % Ruffled Fur 01/27/1986 12/10/85 49.00 No
60 4.0 % Abnormal Posture 03/13/1986 12/10/85 94.00 Yes
60 4.0 % Hypoactivity 03/13/1986 12/10/85 94.00 Yes
60 4.0 % Emaciated 03/13/1986 12/10/85 94.00 Yes
60 4.0 % Ataxia 03/13/1986 12/10/85 94.00 Yes