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Chemical Properties

CAS Registry Number: 65-45-2

Selected information from two of the National Library of Medicine's databases: ChemIDPlus2 and HSDB3.

Names 1

  • 2-Hydroxybenzamide
  • Salicylamide

Structure

Chemical Structure for Chemical Abstracts Service Registry Number 65-45-2 from NLM

Synonyms (Sources: NTP,HSDB,RTECS,MESH)2

  • 2-Carbamoylphenol
  • 2-Hydroxybenzamide
  • 4-10-00-00169 (Beilstein Handbook Reference)
  • Acket
  • Afko-Sal
  • Algamon
  • Algiamida
  • Allevin
  • Amid kyseliny salicylove [Czech]
  • Amid-Sal
  • Amidosal
  • Anamid
  • BRN 0742439
  • Benesal
  • Benzamide, 2-hydroxy-
  • Benzamide, o-hydroxy-
  • Benzoic acid, 2-hydroxy-, amide
  • Cetamide
  • Cymidon
  • Dolomide
  • Dropsprin
  • H.P. 34
  • HSDB 227
  • Liquiprin
  • Morsarinas
  • Novecyl
  • OHB
  • Oramid
  • Panithal
  • Raspberin
  • SR 4326
  • Salamid
  • Salamide
  • Saliamid
  • Saliamin
  • Salicilamide [Italian]
  • Salicim
  • Salicylic acid amide
  • Salipur
  • Salizell
  • Salrin
  • Salymid
  • Serramida
  • Urtosal
  • o-Hydroxybenzamide

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Other Registry Numbers2

  • None Found

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Chemical Properties3

Property Description
Boiling Point
  • 181.5 DEG C @ 14 MM HG
Color/Form
  • WHITE OR SLIGHTLY PINK CRYSTALLINE POWDER
  • YELLOW LEAFLETS FROM DILUTE ALCOHOL
Corrosivity
  • None Found
Critical Temperature & Pressure
  • None Found
Density/Specific Gravity
  • 1.175 @ 140 DEG C/4 DEG C
Dissociation Constants
  • pKa = 8.37 20 deg C
Heat Of Combustion
  • None Found
Heat Of Vaporization
  • None Found
Melting Point
  • 140 DEG C
Molecular Weight
  • 137.13
Odor
  • None Found
Other Chemical/Physical Properties
  • FORMS A WATER-SOLUBLE SODIUM SALT @ PH 9
Relative Evaporation Rate
  • None Found
Solubilities
  • FREELY SOL IN SOLN OF ALKALIES
  • SLIGHTLY SOL IN NAPHTHA, CARBON TETRACHLORIDE
  • SOL IN CHLOROFORM, ALC, ETHER
  • SOLUBILITY IN WATER: 0.2% @ 30 DEG C; 0.8% @ 47 DEG C; IN GLYCEROL: 2.0% @ 5 DEG C; 5.0% @ 39 DEG C; 10.0% @ 60 DEG C; IN PROPYLENE GLYCOL: 10.0% @ 5 DEG C
  • Water solubility = 2.06X10+3 mg/L at 25 deg C
Spectral Properties
  • INDEX OF REFRACTION: 1.595 (ALPHA); 1.637 (BETA); 1.727 (GAMMA) (MONOCLINIC SYSTEM)
  • IR: 1696 (Coblentz Society Spectral Collection)
  • Intense mass spectral peaks: 65 m/z, 92 m/z, 120 m/z, 137 m/z
  • MASS: 86 (Aldermaston, Eight Peak Index of Mass Spectra, UK)
  • MAX ABSORPTION (ALCOHOL): 548 NM (A= 548, 1%, 1 CM); 302 NM (A= 302, 1%, 1 CM)
  • NMR: 6740 (Sadtler Research Laboratories Spectral Collection)
  • SADTLER REFERENCE NUMBER: 3253 (IR, PRISM); 373 (IR, GRATING); MAX ABSORPTION (ALCOHOL): 302 NM (LOG E= 3.62)
  • UV: 973 (Sadtler Research Laboratories Spectral Collection)
Surface Tension
  • None Found
Taste
  • SOMEWHAT BITTER
Vapor Density
  • None Found
Vapor Pressure
  • None Found
Viscosity
  • None Found
log P (octanol-water)
  • Log Kow = 1.28
pH
  • ABOUT 5 @ 28 DEG C (AQ SOLN)

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Uses3

  • MEDICATION (VET): **QC REVIEWED**
  • MEDICATION **QC REVIEWED**

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Notes (Sources: NTP,HSDB,RTECS,MESH)2

  • None Found.

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Superlist Classes2

  • None Found

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Links to Additional Information2

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Footnotes

1 Source: the NTP's CEBS database.

2 Source: the National Library of Medicine's ChemIDPlus, 02/28/2017.

3 Source: the National Library of Medicine's Hazardous Substance Database, 02/28/2017.

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