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Chemical Properties

CAS Registry Number: 66-75-1

Selected information from two of the National Library of Medicine's databases: ChemIDPlus2 and HSDB3.

Names 1

    Structure

    Chemical Structure for Chemical Abstracts Service Registry Number 66-75-1 from NLM

    Synonyms (Sources: NTP,HSDB,RTECS,MESH)2

    • 2,4(1H,3H)-Pyrimidinedione, 5-(bis(2-chloroethyl)amino)-
    • 2,6-Dihydroxy-5-bis(2-chloroethyl)aminopyrimidine
    • 5-(Bis(2-chloroethyl)amino)-2,4(1H,3H)pyrimidinedione
    • 5-(Bis(2-chloroethyl)amino)uracil
    • 5-(Di-(beta-chloroethyl)amino)uracil
    • 5-(Di-2-chloroethyl)aminouracil
    • 5-Aminouracil mustard
    • 5-N,N-Bis(2-chloroethyl)aminouracil
    • Aminouracil mustard
    • CB-4835
    • Chlorethaminacil
    • Demethyldopan
    • Desmethyldopan
    • ENT 50439
    • HSDB 3261
    • NCI-C04820
    • NSC-34462
    • Nordopan
    • RCRA waste number U237
    • SK-19849
    • U-8344
    • Uracil lost [German]
    • Uracil mustard
    • Uracil nitrogen mustard
    • Uracil, 5-(bis(2-chloroethyl)amino)-
    • Uracillost
    • Uracilmostaza
    • Uramustin
    • Uramustine

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    Other Registry Numbers2

    • None Found

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    Chemical Properties3

    Property Description
    Boiling Point
    • None Found
    Color/Form
    • OFF-WHITE, CRYSTALLINE POWDER
    • WHITE CRYSTALS FROM METHANOL & WATER
    Corrosivity
    • None Found
    Critical Temperature & Pressure
    • None Found
    Density/Specific Gravity
    • None Found
    Dissociation Constants
    • None Found
    Heat Of Combustion
    • None Found
    Heat Of Vaporization
    • None Found
    Melting Point
    • None Found
    Molecular Weight
    • 252.10
    Odor
    • ODORLESS
    Other Chemical/Physical Properties
    • DECOMP @ 206 DEG C
    Relative Evaporation Rate
    • None Found
    Solubilities
    • 2 MG/ML IN ACETONE
    • 2 MG/ML IN METHANOL
    • INSOL IN BENZENE
    • SLIGHTLY SOL IN ALCOHOL; PRACTICALLY INSOL IN CHLOROFORM
    • SOL IN DIMETHYLACETAMIDE & 5% AQ SOLN THEREOF
    • SPARINGLY SOL IN WATER
    Spectral Properties
    • MAX ABSORPTION (0.01 N H2SO4 IN 95% ETHANOL): 257 NM (E= 5675)
    Surface Tension
    • None Found
    Taste
    • None Found
    Vapor Density
    • None Found
    Vapor Pressure
    • None Found
    Viscosity
    • None Found
    log P (octanol-water)
    • None Found
    pH
    • None Found

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    Uses3

    • MEDICATION **PEER REVIEWED**

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    Notes (Sources: NTP,HSDB,RTECS,MESH)2

    • Nitrogen mustard derivative of URACIL. It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal and bone marrow damage.

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    Superlist Classes2

    • Overall Carcinogenic Evaluation: Group 2B
    • Reportable Quantity (RQ) = 10 lb

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    Links to Additional Information2

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    Footnotes

    1 Source: the NTP's CEBS database.

    2 Source: the National Library of Medicine's ChemIDPlus, 02/28/2017.

    3 Source: the National Library of Medicine's Hazardous Substance Database, 02/28/2017.

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