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TR-593: Technical Report Pathology Tables and Curves

Pathology Tables, Survival and Growth Curves from NTP
Short-Term and Long-Term Studies

Revisions to the 2,3-Butanedione Subchronic Study in Rats TDMS Tables: The number of 50 ppm male and female rats with eyes examined microscopically has been updated to 10 for males and 10 for females. No additional diagnoses have been made.

DOI: https://doi.org/10.22427/NTP-DATA-TR-593

TR-593: 2,3-Butanedione

Short-Term

3-Month Study Tables - Rats

E03 - Growth Curves (65KB)
E04 - Mean Body Weights and Survival Table (18KB)
E05 - Clinical Observations Summary (18KB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (38KB)
P04 - Neoplasms by Individual Animal (214KB)
P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (34KB)
P09 - Non-Neoplastic Lesions by Individual Animal (249KB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (307KB)
P14 - Individual Animal Pathology Data (312KB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (39KB)
P40 - Survival Curves (435KB)

3-Month Individual Animal Data - Rats

Female Individual Animal Body Weight Data (35KB)
Female Individual Animal Non Neoplastic Pathology Data (101KB)
Female Individual Animal Survival Data (11KB)
Female Individual Animal Terminal Body Weight Data (19KB)
Female Individual Clinical Observations (14KB)
Male Individual Animal Body Weight Data (37KB)
Male Individual Animal Non Neoplastic Pathology Data (100KB)
Male Individual Animal Survival Data (11KB)
Male Individual Animal Terminal Body Weight Data (19KB)
Male Individual Clinical Observations (15KB)
Individual Animal Clinical Chemistry Data (32KB)
Individual Animal Hematology Data (57KB)
Individual Animal Organ Weight Data (13KB)

3-Month Study Tables - Mice

E03 - Growth Curves (441KB)
E04 - Mean Body Weights and Survival Table (18KB)
E05 - Clinical Observations Summary (18KB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (35KB)
P04 - Neoplasms by Individual Animal (213KB)
P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (34KB)
P09 - Non-Neoplastic Lesions by Individual Animal (242KB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (232KB)
P14 - Individual Animal Pathology Data (317KB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (37KB)
P40 - Survival Curves (435KB)

3-Month Individual Animal Data - Mice

Female Individual Animal Body Weight Data (36KB)
Female Individual Animal Clinical Observations (13KB)
Female Individual Animal Non Neoplastic Pathology Data (120KB)
Female Individual Animal Survival Data (11KB)
Female Individual Animal Terminal Body Weight Data (19KB)
Male Individual Animal Body Weight Data (36KB)
Male Individual Animal Clinical Observations (15KB)
Male Individual Animal Non Neoplastic Pathology Data (122KB)
Male Individual Animal Survival Data (11KB)
Male Individual Animal Terminal Body Weight Data (19KB)
Individual Animal Hematology Data (23KB)
Individual Animal Organ Weight Data (12KB)

Long-Term

Chronic Study Tables - Rats

E03 - Growth Curves (71KB)
E04 - Mean Body Weights and Survival Table (25KB)
E05 - Clinical Observations Summary (25KB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (60KB)
P04 - Neoplasms by Individual Animal (648KB)
P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (48KB)
P08 - Statistical Analysis of Primary Tumors (192KB)
P08 - Statistical Analysis of Primary Tumors-Custom Nose (22KB)
P09 - Non-Neoplastic Lesions by Individual Animal (907KB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (526KB)
P11 - Statistical Analysis of Survival Data (24KB)
P14 - Individual Animal Pathology Data (1MB)
P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (607KB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (63KB)
P40 - Survival Curves (446KB)

Chronic Individual Animal Data - Rats

Female Individual Animal Body Weight Data (367KB)
Female Individual Animal Clinical Observations (271KB)
Female Individual Animal Neoplastic Pathology Data (119KB)
Female Individual Animal Non Neoplastic Pathology Data (967KB)
Female Individual Animal Survival Data (34KB)
Female Individual Animal Terminal Body Weight Data (57KB)
Male Individual Animal Body Weight Data (378KB)
Male Individual Animal Clinical Observations (272KB)
Male Individual Animal Neoplastic Pathology Data (77KB)
Male Individual Animal Non Neoplastic Pathology Data (941KB)
Male Individual Animal Survival Data (33KB)
Male Individual Animal Terminal Body Weight Data (57KB)

Chronic Study Tables - Mice

E03 - Growth Curves (454KB)
E04 - Mean Body Weights and Survival Table (24KB)
E05 - Clinical Observations Summary (20KB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (70KB)
P04 - Neoplasms by Individual Animal (748KB)
P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (52KB)
P08 - Statistical Analysis of Primary Tumors (141KB)
P09 - Non-Neoplastic Lesions by Individual Animal (954KB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (712KB)
P11 - Statistical Analysis of Survival Data (24KB)
P14 - Individual Animal Pathology Data (2MB)
P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (632KB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (72KB)
P40 - Survival Curves (443KB)

Chronic Individual Animal Data - Mice

Female Individual Animal Body Weight Data (409KB)
Female Individual Animal Clinical Observations (140KB)
Female Individual Animal Neoplastic Pathology Data (172KB)
Female Individual Animal Non Neoplastic Pathology Data (915KB)
Female Individual Animal Survival Data (33KB)
Female Individual Animal Terminal Body Weight Data (57KB)
Male Individual Animal Body Weight Data (393KB)
Male Individual Animal Clinical Observations (84KB)
Male Individual Animal Neoplastic Pathology Data (122KB)
Male Individual Animal Non Neoplastic Pathology Data (812KB)
Male Individual Animal Survival Data (33KB)
Male Individual Animal Terminal Body Weight Data (57KB)