COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:

TOX-98: Toxicity Report Tables & Curves

Pathology Tables, Survival and Growth Curves from NTP
Short-Term and Genetic Toxicology Studies


Note: The study data are being disseminated prior to external peer review under applicable information quality guidelines and do not represent and should not be construed to represent any final NTP determination or policy.

The PA43 tables were replaced in order to remove unneeded endpoints and allow for greater consistency across studies. The cell count percentage data were removed since it is the absolute cell counts that are evaluated/interpreted. Terms for machine generated and manual hematocrit were updated to be consisted with terms for the same measures. A few additional parameters were also removed.

https://doi.org/10.22427/NTP-DATA-TOX-98

TOX-98: Acetoin & 2,3-Pentanedione

Short-Term


2-Week Acetoin Study Tables - Rats

2-Week Acetoin Individual Animal Data - Rats

2-Week Acetoin Study Tables - Mice

2-Week Acetoin Individual Animal Data - Mice

3-Month Acetoin Study Tables - Rats

3-Month Acetoin Individual Animal Data - Rats

3-Month Acetoin Study Tables - Mice

3-Month Acetoin Individual Animal Data - Mice

3-Month 2,3-Pentanedione Study Tables - Rats

3-Month 2,3-Pentanedione Individual Animal Data - Rats

3-Month 2,3-Pentanedione Study Tables - Mice

3-Month 2,3-Pentanedione Individual Animal Data - Mice

Genetic Toxicology


Genetic Toxicity Evaluation of Acetoin (513-86-0) in Micronucleus Study G99018 in Wistar Han Rats

Genetic Toxicity Evaluation of Acetoin (513-86-0) in Micronucleus Study G99018B in B6C3F1 Mice

Genetic Toxicity Evaluation of Acetoin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A17696

Genetic Toxicity Evaluation of 2,3-Pentanedione (600-14-6) in Micronucleus Study G08010 in Wistar Han Rats

Genetic Toxicity Evaluation of 2,3-Pentanedione (600-14-6) in Micronucleus Study G08010B in B6C3F1 Mice