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ADME/TK Evaluation (K06049) of 2-Methoxy-4-nitroaniline (97-52-9) in Harlan Sprague-Dawley Rats and B6C3F1 Mice Exposed via Gavage Administration, Intravenous Injection or Dermal Application

Radiolabel Description:
Carbon-14; 2-Methoxy-4-nitroaniline, [ring-14C(U)]- 

Intravenous, PEG400:ethanol:saline (60:10:30); Oral, Cremophor; Dermal, acetone.

Mathews JM, Zhan Q, Etheridge AS, Patel PR, Black SR, Banks TT, Fennell TR, Snyder RW, Burgess JP, Warren SD, Surh I, Waidyanatha S.
Metabolism and disposition of 2-methoxy-4-nitroaniline in male and female Harlan Sprague Dawley rats and B6C3F1/N mice.
Xenobiotica. 2012 Dec;42(12):1213-24. doi: Epub 2012 Jun 23. PMID: 22725680

Data Summary - Male Rats

Data Summary - Female Rats

Data Summary - Male Mice

Data Summary - Female Mice