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ADME/TK Evaluation (K10022) of Hydroquinone (123-31-9) in Harlan Sprague-Dawley Rats and B6C3F1/N Mice Exposed via Gavage Administration, Intravenous Injection or Dermal Application

Radiolabel Description:
Carbon-14 uniformly in the ring; Hydroquinone, [ring-14C(U)]-

Intravenous, saline; Oral, distilled water; Dermal, 95% ethanol

Black SR, Fennell TR, Mathews JM, Snyder RW, Patel PR, Watson SL, Sutherland V, Waidyanatha S.
Disposition of [14C]hydroquinone in Harlan Sprague-Dawley rats and B6C3F1/N mice: species and route comparison.
Xenobiotica. 2018 Nov;48(11):1128-1141. doi: Epub 2017 Nov 22. PMID: 29166815

Data Summary - Male Rats

Data Summary - Female Rats

Data Summary - Male Mice

Data Summary - Female Mice

Summary Data-Toxicokinetics