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RR-8: NTP Research Report on In Vivo Repeat Dose Biological Potency Study of Triphenyl Phosphate (CAS No. 115-86-6) in Male Sprague Dawley Rats (Hsd: Sprague Dawley SD) (Gavage Studies)

DOI: https://doi.org/10.22427/NTP-DATA-RR-8
GEO: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE121134
TGX BMD Response: https://manticore.niehs.nih.gov/tgxbenchmarkdoseresponse/chemical?chemical_type=Triphenyl+Phosphate&submit=Show+Results

Short-Term

Benchmark Dose Analysis

BMDExpress Project File (17MB)
Appendix (1MB)
BMD Apical Endpoint Model Fits (2MB)
BMDExpress Software (67MB)
BMDExpress Project File (JSON format) (79MB)
BMDExpress Expression Data (5MB)
BMDExpress GO Biological Process BMD Results (9MB)
BMDExpress GO Biological Process Deduplicated BMD Results (7MB)
BMDExpress Individual Gene BMD Results (435KB)
BMDExpress Individual Probe Set BMD Results (2MB)
BMDExpress Prefilter Results (200KB)
Model Parameters (291KB)
Batch Correction Documentation (26MB)
GO Biological Process BMD Analysis Results (3MB)
Individual Gene BMD Analysis Results File (266KB)
Microarray Files (49MB)

Summary Tables

Table 1 - Mean Body Weight Summary (44KB)
Table 2 - Organ Weights Summary (48KB)
Table 3 - Clinical Chemistry Summary (48KB)
Table 4 - Hormone and Enzymes Summary (109KB)
Table 5 - BMD, NOEL and LOEL Summary for Apical Endpoints (22KB)
Table 6 - Top 20 GO Biological Process Gene Sets (98KB)