Evaluation of the Chronic Toxicity and Carcinogenicity (C20614) of Perfluorooctanoic Acid (PFOA) (335-67-1) in Harlan Sprague Dawley Rats Exposed via Dosed Feed (2 Year Females & 16 Week Males)
Pathology Tables, Survival and Growth Curves from NTP Studies
Long-Term
Interim (16 Week) of Chronic Study One (C20614) – Male and Female Rats
- E01 - Animal Removal Summary By Treatment Group (12KB)
- E02 - Animals Removed from Experiment (57KB)
- E05 - Clinical Observations Summary (23KB)
- E08 - Feed Water and Compound Consumption Table (33KB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (34KB)
- P04 - Neoplasms by Individual Animal (272KB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (33KB)
- P09 - Non-Neoplastic Lesions by Individual Animal (306KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - Females 0-0, 0-300, 0-1000 (62KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - Females 0-0, 150-300, 300-1000 (57KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - Females 0-1000, 300-1000 (58KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - Females 0-300, 150-300 (29KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - Males 0-0, 0-150, 0-300 (73KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - Males 0-0, 150-150, 300-300 (73KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - Males 0-150, 150-150 (48KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - Males 0-300, 300-300 (66KB)
- P14 - Individual Animal Pathology Data (276KB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (273KB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (36KB)
- PA06 - Organ Weights Summary (165KB)
- PA41 - Clinical Chemistry Summary (171KB)
- PA45 - Liver Special Studies Summary (67KB)
- PA48 - Tissue Concentration Summary (80KB)
- R02 - Reproductive Performance Summary (38KB)
Chronic Study One (C20614) - Male and Female Rats
- E01 - Animal Removal Summary By Treatment Group (12KB)
- E02 - Animals Removed from Experiment (96KB)
- E03 - Growth Curves - litter (0-0, 0-150, 0-300) male (31KB)
- E03 - Growth Curves - litter (0-0, 0-300, 0-1000) female (35KB)
- E03 - Growth Curves - litter (0-0, 150-150, 300-300) male (32KB)
- E03 - Growth Curves - litter (0-0, 150-300, 300-1000) female (36KB)
- E03 - Growth Curves - litter (0-1000, 300-1000) female (31KB)
- E03 - Growth Curves - litter (0-150, 150-150) male (28KB)
- E03 - Growth Curves - litter (0-300, 150-300) female (30KB)
- E03 - Growth Curves - litter (0-300, 300-300) male (28KB)
- E04 - Mean Body Weights and Survival Table litter (0-0, 0-300, 0-1000) female (11KB)
- E04 - Mean Body Weights and Survival Table litter (0-0, 150-300, 300-1000) female (11KB)
- E04 - Mean Body Weights and Survival Table litter (0-0,0-150,0-300) male (8KB)
- E04 - Mean Body Weights and Survival Table litter (0-0,150-150,300-300) male (8KB)
- E04 - Mean Body Weights and Survival Table litter (0-1000, 300-1000) female (10KB)
- E04 - Mean Body Weights and Survival Table litter (0-150,150-150) male (8KB)
- E04 - Mean Body Weights and Survival Table litter (0-300, 150-300) female (10KB)
- E04 - Mean Body Weights and Survival Table litter (0-300, 300-300) male (8KB)
- E05 - Clinical Observations Summary (23KB)
- E08 - Feed Water and Compound Consumption Table (33KB)
- F0 Female Harlan Sprague Dawley Rats Post-Cull Pup Body Weights (21KB)
- F0 Female Harlan Sprague Dawley Rats Gestational Body and Body Weight Gains (19KB)
- F0 Female Harlan Sprague Dawley Rats Gestational and Lactational Chemical Consumption (19KB)
- F0 Female Harlan Sprague Dawley Rats Gestational and Lactational Food Consumption (20KB)
- F0 Female Harlan Sprague Dawley Rats Lactational Body and Body Weight Gains (19KB)
- F0 Litter Data Analysis in Female Harlan Sprague Dawley Rats: Live Litter Size and Survival (22KB)
- F0 Litter Data Analysis in Female Harlan Sprague Dawley Rats: PND1 Data (21KB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (35KB)
- P04 - Neoplasms by Individual Animal (414KB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (32KB)
- P08 - Statistical Analysis of Primary Tumors - Uterine 0-0 0-300 0-1000 (74KB)
- P08 - Statistical Analysis of Primary Tumors - Uterine 0-0 150-300 300-1000 (55KB)
- P08 - Statistical Analysis of Primary Tumors - Uterine 0-1000 300-1000 (57KB)
- P08 - Statistical Analysis of Primary Tumors - Uterine 0-300 150-300 (48KB)
- P08 - Statistical Analysis of Primary Tumors - litter 0-0 0-300 0-1000 (54KB)
- P08 - Statistical Analysis of Primary Tumors - litter 0-0 150-300 300-1000 (62KB)
- P08 - Statistical Analysis of Primary Tumors - litter 0-1000 300-1000 (59KB)
- P08 - Statistical Analysis of Primary Tumors - litter 0-300 150-300 (40KB)
- P09 - Non-Neoplastic Lesions by Individual Animal (490KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - Uterine 0-0 0-300 0-1000 (112KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - Uterine 0-0 150-300 300-1000 (88KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - Uterine 0-1000 300-1000 (80KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - Uterine 0-300 150-300 (82KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - litter (0-0, 0-300, 0-1000) (154KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - litter (0-0, 150-300, 300-1000) (156KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - litter (0-1000, 300-1000) (128KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - litter (0-300, 150-300) (118KB)
- P11 - Statistical Analysis of Survival Data - litter (0-0, 0-300, 0-1000) (12KB)
- P11 - Statistical Analysis of Survival Data - litter (0-0, 150-300, 300-1000) (12KB)
- P11 - Statistical Analysis of Survival Data - litter (0-1000, 300-1000) (12KB)
- P11 - Statistical Analysis of Survival Data - litter (0-300, 150-300) (11KB)
- P14 - Individual Animal Pathology Data (858KB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (372KB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (36KB)
- P18_-_Incidence_Rates_of_Non-Neoplastic_Lesions_by_Anatomic_Site_with_Average_Severity_Grades-Uterine_Hyperplasia_ (2MB)
- P40 - Survival Curves - 0-0, 0-300, 0-1000 (33KB)
- P40 - Survival Curves - 0-0, 150-300, 300-1000 (33KB)
- P40 - Survival Curves - 0-1000, 300-1000 (31KB)
- P40 - Survival Curves - 0-300, 150-300 (30KB)
- P40 - Survival Curves - All Treatments (35KB)
Chronic Individual Animal Data of Study One (C20614) - Male and Female Rats
- Female Individual Animal Body Weight All Animals (610KB)
- Female Individual Animal Neoplastic Pathology Data (160KB)
- Female Individual Animal Non Neoplastic Pathology Data (1MB)
- Female Individual Animal Survival Data (50KB)
- Female Individual Animal Terminal Body Weight Data (85KB)
- Female Individual Clinical Observations (238KB)
- Male Individual Animal Body Weight All Animals (180KB)
- Male Individual Animal Neoplastic Pathology Data (2KB)
- Male Individual Animal Non Neoplastic Pathology Data (109KB)
- Male Individual Animal Survival Data (47KB)
- Male Individual Clinical Observations (3KB)
- Individual Animal Clinical Chemistry Data (13KB)
- Individual Animal DamID and PupID Data (26KB)
- Individual Animal Liver Special Studies Data (7KB)
- Individual Animal Organ Weight Data (14KB)
- Individual Animal Reproductive Performance Data (12KB)
- Individual Animal Tissue Concentration Data (10KB)