Evaluation of the Chronic Toxicity and Carcinogenicity (C20614B) of Perfluorooctanoic Acid (PFOA) (335-67-1) in Male Harlan Sprague Dawley Rats Exposed via Dosed Feed
Pathology Tables, Survival and Growth Curves from NTP Studies
Long-Term
Interim (16 Week) of Chronic Study Two (C20614B) – Male Rats
- E01 - Animal Removal Summary By Treatment Group (12KB)
- E02 - Animals Removed from Experiment (47KB)
- E05 - Clinical Observations Summary (24KB)
- E08 - Feed Water and Compound Consumption Table (34KB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (26KB)
- P04 - Neoplasms by Individual Animal (98KB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (27KB)
- P09 - Non-Neoplastic Lesions by Individual Animal (101KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - Males 0-0, 0-20, 0-40, 0-80 (25KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - Males 0-0, 300-0 (13KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - Males 0-20, 300-20 (22KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - Males 0-40, 300-40 (20KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - Males 0-80, 300-80 (22KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - Males 300-0, 300-20, 300-40, 300-80 (25KB)
- P14 - Individual Animal Pathology Data (166KB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (99KB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (27KB)
- PA48 - Tissue Concentration Summary (75KB)
- R02 - Reproductive Performance Summary (36KB)
Chronic Study Two (C20614B) – Male Rats
- E01 - Animal Removal Summary By Treatment Group (12KB)
- E02 - Animals Removed from Experiment (118KB)
- E03 - Growth Curves - litter (0-0, 0-20, 0-40, 0-80) (37KB)
- E03 - Growth Curves - litter (0-0, 300-0) (31KB)
- E03 - Growth Curves - litter (0-20, 300-20) (31KB)
- E03 - Growth Curves - litter (0-40, 300-40) (31KB)
- E03 - Growth Curves - litter (0-80, 300-80) (30KB)
- E03 - Growth Curves - litter (300-0, 300-20, 300-40, 300-80) (37KB)
- E04 - Mean Body Weights and Survival Table litter (0-0, 0-20, 0-40, 0-80) (12KB)
- E04 - Mean Body Weights and Survival Table litter (0-0, 300-0) (10KB)
- E04 - Mean Body Weights and Survival Table litter (0-20, 300-20) (10KB)
- E04 - Mean Body Weights and Survival Table litter (0-40, 300-40) (10KB)
- E04 - Mean Body Weights and Survival Table litter (0-80, 300-80) (10KB)
- E04 - Mean Body Weights and Survival Table litter (300-0, 300-20, 300-40, 300-80) (12KB)
- E05 - Clinical Observations Summary (25KB)
- E08 - Feed Water and Compound Consumption Table (34KB)
- F0 Female Harlan Sprague Dawley Rats Gestational Body and Body Weight Gains (17KB)
- F0 Female Harlan Sprague Dawley Rats Gestational and Lactational Chemical Consumption (18KB)
- F0 Female Harlan Sprague Dawley Rats Gestational and Lactational Food Consumption (18KB)
- F0 Female Harlan Sprague Dawley Rats Lactational Body and Body Weight Gains (17KB)
- F0 Litter Data Analysis in Female Harlan Sprague Dawley Rats: Male Pup Body Weights (16KB)
- F0 Litter Data Analysis in Female Harlan Sprague Dawley Rats: PND1 Data (18KB)
- F0 Litter Data Analysis in Female Harlan Sprague Dawley Rats: PND4 Data (17KB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (64KB)
- P04 - Neoplasms by Individual Animal (654KB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (52KB)
- P08 - Statistical Analysis of Primary Tumors - litter(0-0, 0-20, 0-40, 0-80) (78KB)
- P08 - Statistical Analysis of Primary Tumors - litter(0-0, 300-0) (61KB)
- P08 - Statistical Analysis of Primary Tumors - litter(0-20, 300-20) (68KB)
- P08 - Statistical Analysis of Primary Tumors - litter(0-40, 300-40) (47KB)
- P08 - Statistical Analysis of Primary Tumors - litter(0-80, 300-80) (49KB)
- P08 - Statistical Analysis of Primary Tumors - litter(300-0, 300-40, 300-60, 300-80) (78KB)
- P09 - Non-Neoplastic Lesions by Individual Animal (830KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - litter(0-0, 0-20, 0-40, 0-80) (182KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - litter(0-0, 300-0) (133KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - litter(0-20, 300-20) (135KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - litter(0-40, 300-40) (143KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - litter(0-80, 300-80) (132KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - litter(300-0, 300-20, 300-40, 300-80) (173KB)
- P11 - Statistical Analysis of Survival Data - litter (0-0, 0-20, 0-40, 0-80) (12KB)
- P11 - Statistical Analysis of Survival Data - litter (0-0, 300-0) (11KB)
- P11 - Statistical Analysis of Survival Data - litter (0-20, 300-20) (11KB)
- P11 - Statistical Analysis of Survival Data - litter (0-40, 300-40) (11KB)
- P11 - Statistical Analysis of Survival Data - litter (0-80, 300-80) (11KB)
- P11 - Statistical Analysis of Survival Data - litter (300-0, 300-20, 300-40, 300-80) (12KB)
- P14 - Individual Animal Pathology Data (1MB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (585KB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (66KB)
- P40 - Survival Curves - 0-0, 0-20, 0-40, 0-80 (31KB)
- P40 - Survival Curves - 0-0, 300-0 (29KB)
- P40 - Survival Curves - 0-20, 300-20 (29KB)
- P40 - Survival Curves - 0-40, 300-40 (29KB)
- P40 - Survival Curves - 0-80, 300-80 (29KB)
- P40 - Survival Curves - 300-0, 300-20, 300-40, 300-80 (31KB)
- P40 - Survival Curves - All Treatment Groups (36KB)
Chronic Individual Animal Data of Study Two (C20614B) - Male Rats
- 002-02657-0004-0000-6 Male IndividualBodyWeightAllAnimals (1MB)
- Male Individual Animal Neoplastic Pathology Data (223KB)
- Male Individual Animal Non Neoplastic Pathology Data (2MB)
- Male Individual Animal Survival Data (78KB)
- Male Individual Animal Terminal Body Weight Data (134KB)
- Male Individual Clinical Observations (226KB)
- Individual Animal Clinical Chemistry Data (12KB)
- Individual Animal DamID and PupID Data (24KB)
- Individual Animal Liver Special Studies Data (8KB)
- Individual Animal Organ Weight Data (11KB)
- Individual Animal Reproductive Performance Data (16KB)
- Individual Animal Tissue Concentration Data (12KB)