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Short-Term Study Body Weights

Study Information:

Chemical Name: 1020 Long Multiwalled Carbon Nanotube
CASRN: ="L-MWNT-1020"
Study Number: C07062
Exposure Route: RESPIRATORY EXPOSURE WHOLE BODY
TDMS Number: 0706201
Sex: Female
Strain and Species: HSD Rats

Animal Number Cage Number Dose Group Days On Study Week 1 Week 2 Week 3 Week 4 Week 5 Week 7 Week 11 Week 23 Removal Reason
101 8 Vehicle Control 73 116 148.5 172.8 189.3 219.5 SSAC w/o Nec
102 8 Vehicle Control 32 98.7 132.1 155.3 168.6 184.8 Terminal Sacrifice
103 8 Vehicle Control 32 103.6 138.9 163.6 176.7 191.6 Terminal Sacrifice
104 8 Vehicle Control 32 107.5 139.1 160.4 186.9 199.2 Terminal Sacrifice
105 8 Vehicle Control 31 109.1 134.9 152.1 172.2 168.4 SSAC w/o Nec
106 9 Vehicle Control 73 111.9 150.2 170.7 182.3 227.8 SSAC w/o Nec
107 9 Vehicle Control 32 108.9 143.1 167.1 185.4 196.5 Terminal Sacrifice
108 9 Vehicle Control 32 101.6 141.5 166.6 176.2 192.1 Terminal Sacrifice
109 9 Vehicle Control 157 102 141.9 172.4 181.2 257.5 SSAC w/o Nec
110 9 Vehicle Control 45 109.4 143.5 169 176.5 206.1 SSAC w/o Nec
111 10 Vehicle Control 157 116.9 143.4 171.5 186.8 261.6 SSAC w/o Nec
112 10 Vehicle Control 31 112.4 149.5 172.3 185 185.2 SSAC w/o Nec
113 10 Vehicle Control 32 108.2 145.6 175.1 192.5 206.6 Terminal Sacrifice
114 10 Vehicle Control 31 102.9 138.4 166.6 185.7 183.6 SSAC w/o Nec
115 10 Vehicle Control 45 107.8 135.7 159.9 175.7 200.2 SSAC w/o Nec
116 11 Vehicle Control 31 118.1 156.2 184.9 200.3 199.8 SSAC w/o Nec
117 11 Vehicle Control 31 109.1 144.5 164 177.9 175.5 SSAC w/o Nec
118 11 Vehicle Control 31 110.5 137.3 154.5 176.5 174.8 SSAC w/o Nec
119 11 Vehicle Control 73 95.4 121.2 143.6 155.3 203.5 SSAC w/o Nec
120 11 Vehicle Control 32 95.3 129.8 159.7 170.9 177.8 Terminal Sacrifice
121 12 Vehicle Control 45 107.7 149 170.6 195 220 SSAC w/o Nec
122 12 Vehicle Control 31 105 134 157.1 169.8 167.5 SSAC w/o Nec
123 12 Vehicle Control 45 113.7 142.2 172.8 187.4 205.8 SSAC w/o Nec
124 12 Vehicle Control 32 119 148.3 173 194.4 203.2 Terminal Sacrifice
125 12 Vehicle Control 157 104.5 143 168.3 180.6 254.6 SSAC w/o Nec
126 13 Vehicle Control 31 104.8 140.5 167.1 187.5 188.5 SSAC w/o Nec
127 13 Vehicle Control 32 101.7 135.2 160.7 176.5 183.6 Terminal Sacrifice
128 13 Vehicle Control 73 115.7 145.1 166.1 180.8 233 SSAC w/o Nec
129 13 Vehicle Control 31 106.2 141.7 171.3 189 184.1 SSAC w/o Nec
130 13 Vehicle Control 157 105.2 137.2 160.2 171 246.5 SSAC w/o Nec
131 14 Vehicle Control 157 113.4 143.1 171.1 188 257.2 SSAC w/o Nec
132 14 Vehicle Control 45 94.8 139.1 163.3 176.3 201.1 SSAC w/o Nec
133 14 Vehicle Control 32 112 147.2 177.1 190.7 204.9 Terminal Sacrifice
134 14 Vehicle Control 31 115.9 151.1 178.6 198.6 191 SSAC w/o Nec
135 14 Vehicle Control 73 100.3 137 159.1 169.9 229.1 SSAC w/o Nec
301 22 0.1mg/m3 73 101.4 135.8 157.9 167.5 211.8 SSAC w/o Nec
302 22 0.1mg/m3 32 110.7 143.2 170.6 188.5 193.8 Terminal Sacrifice
303 22 0.1mg/m3 32 98 129.5 150.4 168 175.9 Terminal Sacrifice
304 22 0.1mg/m3 32 113.4 144.1 169.5 183.6 197.5 Terminal Sacrifice
305 22 0.1mg/m3 31 105.9 145.1 174.1 191.8 189 SSAC w/o Nec
306 23 0.1mg/m3 73 112.1 140.3 162.6 177.9 216.2 SSAC w/o Nec
307 23 0.1mg/m3 32 106.3 134 151.4 167.2 172.1 Terminal Sacrifice
308 23 0.1mg/m3 32 108.6 131.3 144.6 154.3 164.2 Terminal Sacrifice
309 23 0.1mg/m3 157 119.4 144.3 161.8 174.5 249.5 SSAC w/o Nec
310 23 0.1mg/m3 45 103.8 142.1 171.5 185.4 213.7 SSAC w/o Nec
311 24 0.1mg/m3 157 102.2 139.4 162.5 177.7 256 SSAC w/o Nec
312 24 0.1mg/m3 31 114.6 144.4 171.6 188.1 189.8 SSAC w/o Nec
313 24 0.1mg/m3 32 116.2 152.4 182.6 201.7 209.6 Terminal Sacrifice
314 24 0.1mg/m3 31 118.1 152.5 183.5 200.6 196.3 SSAC w/o Nec
315 24 0.1mg/m3 45 109.1 138.7 164.2 177.1 198.9 SSAC w/o Nec
316 25 0.1mg/m3 31 104.3 140.2 166.5 178.4 175.4 SSAC w/o Nec
317 25 0.1mg/m3 31 104.3 136.3 159.2 174 171.9 SSAC w/o Nec
318 25 0.1mg/m3 31 105.5 129.5 155.3 170.8 173.7 SSAC w/o Nec
319 25 0.1mg/m3 73 102.2 141.6 175.3 185.6 248.1 SSAC w/o Nec
320 25 0.1mg/m3 32 117 142.1 164.7 187.2 193.7 Terminal Sacrifice
321 26 0.1mg/m3 45 99.7 121.9 137.5 151.6 167.8 SSAC w/o Nec
322 26 0.1mg/m3 31 93.6 134.2 158.9 167.7 163.7 SSAC w/o Nec
323 26 0.1mg/m3 45 116.9 150.3 179.8 192.8 220 SSAC w/o Nec
324 26 0.1mg/m3 32 98.5 139.7 171.1 186.7 204.2 Terminal Sacrifice
325 26 0.1mg/m3 157 109.4 146.9 171.5 184.9 268 SSAC w/o Nec
326 27 0.1mg/m3 31 109.7 141.6 165.4 182.8 179.7 SSAC w/o Nec
327 27 0.1mg/m3 32 100.9 135.8 170.6 187.7 199.6 Terminal Sacrifice
328 27 0.1mg/m3 73 105.6 143.2 170.7 185.4 231.8 SSAC w/o Nec
329 27 0.1mg/m3 31 107.4 136.1 158.6 176.2 180.3 SSAC w/o Nec
330 27 0.1mg/m3 157 105.3 145.7 174.9 190.2 274.2 SSAC w/o Nec
331 28 0.1mg/m3 157 103.6 144.6 174.6 189.8 271.9 SSAC w/o Nec
332 28 0.1mg/m3 45 110.8 142.7 166.9 191.8 216.9 SSAC w/o Nec
333 28 0.1mg/m3 32 105.8 139.5 179.1 196.6 205.5 Terminal Sacrifice
334 28 0.1mg/m3 31 116.2 147.4 174 194.1 195 SSAC w/o Nec
335 28 0.1mg/m3 73 115 154.3 182.5 194.8 237.2 SSAC w/o Nec
501 36 0.3mg/m3 73 96.8 133.4 162.5 176 215.7 SSAC w/o Nec
502 36 0.3mg/m3 32 109.4 145 175.1 194.2 206.6 Terminal Sacrifice
503 36 0.3mg/m3 32 102.5 141.3 162.6 180.6 192.5 Terminal Sacrifice
504 36 0.3mg/m3 32 105.9 139.3 167.2 178 191.4 Terminal Sacrifice
505 36 0.3mg/m3 31 101.9 135.1 164.9 179.2 177.6 SSAC w/o Nec
506 37 0.3mg/m3 73 112.3 144.4 168.9 183.3 235.2 SSAC w/o Nec
507 37 0.3mg/m3 32 108.9 145.7 168.2 187 191.6 Terminal Sacrifice
508 37 0.3mg/m3 32 106.4 142.1 171.3 187.4 193.9 Terminal Sacrifice
509 37 0.3mg/m3 157 115.5 149.5 174.3 182.1 288.5 SSAC w/o Nec
510 37 0.3mg/m3 45 103.8 131.8 150.4 170.7 198.3 SSAC w/o Nec
511 38 0.3mg/m3 157 113.4 154 183.3 195.3 266.4 SSAC w/o Nec
512 38 0.3mg/m3 31 101.6 138.1 165.9 180.4 181 SSAC w/o Nec
513 38 0.3mg/m3 32 125.3 156.9 187.6 196.6 206.2 Terminal Sacrifice
514 38 0.3mg/m3 31 103.5 139.9 173.9 196 193.5 SSAC w/o Nec
515 38 0.3mg/m3 45 96.3 126.6 151.1 167.4 188.1 SSAC w/o Nec
516 39 0.3mg/m3 31 101.7 135.9 163.6 175.9 176.8 SSAC w/o Nec
517 39 0.3mg/m3 31 102.9 145.1 173.4 192.2 188 SSAC w/o Nec
518 39 0.3mg/m3 31 105.1 133.5 153 171.4 174.7 SSAC w/o Nec
519 39 0.3mg/m3 73 96.1 141.3 175.2 190.7 237.2 SSAC w/o Nec
520 39 0.3mg/m3 32 108.6 146 172.3 190 194.5 Terminal Sacrifice
521 40 0.3mg/m3 45 95.8 132.2 157.9 171.7 188.1 SSAC w/o Nec
522 40 0.3mg/m3 31 103.6 141.7 170.1 181.2 181.1 SSAC w/o Nec
523 40 0.3mg/m3 45 106 125.9 154.9 169.5 191.2 SSAC w/o Nec
524 40 0.3mg/m3 32 90.9 125.1 151.7 169.2 177.6 Terminal Sacrifice
525 40 0.3mg/m3 157 106.6 132.1 161.3 176.3 242.6 SSAC w/o Nec
526 41 0.3mg/m3 31 108.9 144.3 165.4 177.6 174.8 SSAC w/o Nec
527 41 0.3mg/m3 32 108.8 139.9 166.9 189.1 204.8 Terminal Sacrifice
528 41 0.3mg/m3 73 117.1 143.5 165.8 176.8 225.5 SSAC w/o Nec
529 41 0.3mg/m3 31 98.7 123.5 146.1 165.9 164.2 SSAC w/o Nec
530 41 0.3mg/m3 157 107 144.3 166 183.5 262.8 SSAC w/o Nec
531 42 0.3mg/m3 157 115.1 146.4 170.2 185.2 254.9 SSAC w/o Nec
532 42 0.3mg/m3 45 112.3 141.8 167 177.3 200.7 SSAC w/o Nec
533 42 0.3mg/m3 32 108.4 141.2 167.3 186.8 192.5 Terminal Sacrifice
534 42 0.3mg/m3 31 101.5 140.6 168.2 188.9 185.3 SSAC w/o Nec
535 42 0.3mg/m3 73 95.5 126.4 150.4 168.1 212.6 SSAC w/o Nec
701 50 1mg/m3 73 109.9 141 173.2 188.2 242.8 SSAC w/o Nec
702 50 1mg/m3 32 113.7 145.2 170.7 184.7 196.5 Terminal Sacrifice
703 50 1mg/m3 32 99.5 138.1 156.2 173.7 188 Terminal Sacrifice
704 50 1mg/m3 32 110.4 146.7 174.4 190.2 203.5 Terminal Sacrifice
705 50 1mg/m3 31 105.9 144.1 173.6 189.8 186 SSAC w/o Nec
706 51 1mg/m3 73 105.2 138.9 159.5 178.8 239.9 SSAC w/o Nec
707 51 1mg/m3 32 100 137 174.7 170.8 178.6 Terminal Sacrifice
708 51 1mg/m3 32 107 133 156.9 165.3 175.4 Terminal Sacrifice
709 51 1mg/m3 157 91.8 129.4 144 162.9 255.1 SSAC w/o Nec
710 51 1mg/m3 45 109.8 142.8 152.9 188.1 215.7 SSAC w/o Nec
711 52 1mg/m3 157 97.8 134.4 158.5 172.1 251.2 SSAC w/o Nec
712 52 1mg/m3 31 119.4 144 164.2 181.9 180.9 SSAC w/o Nec
713 52 1mg/m3 32 103.2 141.1 163.9 182.6 197.5 Terminal Sacrifice
714 52 1mg/m3 31 103.9 134.7 156.7 173.2 172.5 SSAC w/o Nec
715 52 1mg/m3 45 107.2 139.5 165.5 184.4 212.9 SSAC w/o Nec
716 53 1mg/m3 31 95.5 128 158.7 178 176.6 SSAC w/o Nec
717 53 1mg/m3 31 114.8 141.9 165.2 179 181.2 SSAC w/o Nec
718 53 1mg/m3 31 112.3 146.5 171.3 188.2 189.2 SSAC w/o Nec
719 53 1mg/m3 73 114.1 144.9 166.5 184.6 232.8 SSAC w/o Nec
720 53 1mg/m3 32 105.8 144.1 166.1 183 192.5 Terminal Sacrifice
721 54 1mg/m3 45 106.2 141.3 164.2 172 190.4 SSAC w/o Nec
722 54 1mg/m3 31 102 139.4 161.2 179.8 177.4 SSAC w/o Nec
723 54 1mg/m3 45 100.7 136.2 162.2 177.1 197.4 SSAC w/o Nec
724 54 1mg/m3 32 114.9 147.6 171.6 187.1 194.5 Terminal Sacrifice
725 54 1mg/m3 157 111.5 145.6 171 183.8 262 SSAC w/o Nec
726 55 1mg/m3 31 101.8 130.6 146.6 166.9 169.1 SSAC w/o Nec
727 55 1mg/m3 32 115.8 143.6 158.4 170.4 180.3 Terminal Sacrifice
728 55 1mg/m3 73 100.4 136.9 159.5 177.7 220.5 SSAC w/o Nec
729 55 1mg/m3 31 101.9 127.9 150.7 159.3 162.5 SSAC w/o Nec
730 55 1mg/m3 157 116.6 155.9 179.3 199.7 293 SSAC w/o Nec
731 56 1mg/m3 157 108 138.1 155.9 177.9 240.2 SSAC w/o Nec
732 56 1mg/m3 45 100.5 138.6 166 179.2 210.4 SSAC w/o Nec
733 56 1mg/m3 32 108.3 139.5 176.1 194.1 208 Terminal Sacrifice
734 56 1mg/m3 31 103 138.8 157.5 170.8 174.8 SSAC w/o Nec
735 56 1mg/m3 73 110.3 146.5 171.7 188.6 237.1 SSAC w/o Nec
901 64 3mg/m3 73 103.8 143.7 166.9 181.9 235.7 SSAC w/o Nec
902 64 3mg/m3 32 106.8 144.4 171.5 191.5 205.7 Terminal Sacrifice
903 64 3mg/m3 32 107.9 137.2 156.3 176.8 187.6 Terminal Sacrifice
904 64 3mg/m3 32 105.3 141.8 172.5 186.4 200.3 Terminal Sacrifice
905 64 3mg/m3 31 103.2 135.4 159.8 176.3 175.2 SSAC w/o Nec
906 65 3mg/m3 73 99.9 131.9 155 171.7 223.8 SSAC w/o Nec
907 65 3mg/m3 32 108.8 139.2 162.7 178.3 185.7 Terminal Sacrifice
908 65 3mg/m3 32 108.1 142.1 170.1 187.4 199.4 Terminal Sacrifice
909 65 3mg/m3 157 108.4 141.2 168.2 188.1 285.1 SSAC w/o Nec
910 65 3mg/m3 45 105.5 134.6 158.8 172.2 192.9 SSAC w/o Nec
911 66 3mg/m3 157 115.5 149.3 179.3 198.3 280.8 SSAC w/o Nec
912 66 3mg/m3 31 98.8 140.5 163.6 176.9 181.9 SSAC w/o Nec
913 66 3mg/m3 32 116.3 149.9 176.7 195 203.7 Terminal Sacrifice
914 66 3mg/m3 31 115.3 147.2 170.1 180.1 182.5 SSAC w/o Nec
915 66 3mg/m3 45 108.7 142.8 171.8 193.8 215.5 SSAC w/o Nec
916 67 3mg/m3 31 113.1 145 167.3 180.4 185.9 SSAC w/o Nec
917 67 3mg/m3 31 112.4 143.4 164.7 181.3 183.5 SSAC w/o Nec
918 67 3mg/m3 31 108.5 140.7 168.1 186.5 185.2 SSAC w/o Nec
919 67 3mg/m3 73 96 138.8 165.2 188.3 234.5 SSAC w/o Nec
920 67 3mg/m3 32 96.7 126.4 144.7 162.9 173.6 Terminal Sacrifice
921 68 3mg/m3 45 100.1 131.8 153.3 171.4 196.1 SSAC w/o Nec
922 68 3mg/m3 31 120.4 161.7 184.1 202.7 204.8 SSAC w/o Nec
923 68 3mg/m3 45 114 146.9 173.4 190.9 214.3 SSAC w/o Nec
924 68 3mg/m3 32 107.4 143 179.9 201.2 214 Terminal Sacrifice
925 68 3mg/m3 157 99.4 139 161.4 179.9 250.5 SSAC w/o Nec
926 69 3mg/m3 31 98.6 138.2 167.7 190 188.5 SSAC w/o Nec
927 69 3mg/m3 32 102.8 131.9 147.9 161.2 179.9 Terminal Sacrifice
928 69 3mg/m3 73 102.9 136.9 166.5 187 240.2 SSAC w/o Nec
929 69 3mg/m3 31 107.7 143.9 172 190.6 188 SSAC w/o Nec
930 69 3mg/m3 157 99 139.1 160.7 176.8 261.4 SSAC w/o Nec
931 70 3mg/m3 157 102.5 135.8 161.1 179.8 262.2 SSAC w/o Nec
932 70 3mg/m3 45 98.8 132.7 153.4 172.4 193.4 SSAC w/o Nec
933 70 3mg/m3 32 116.8 153.3 179.6 194.2 203.2 Terminal Sacrifice
934 70 3mg/m3 31 114.1 148.1 168.3 188.9 186.7 SSAC w/o Nec
935 70 3mg/m3 73 105.6 135 154.6 167.6 209.9 SSAC w/o Nec
1101 78 10mg/m3 73 102.6 136.3 154.9 170.6 214.4 SSAC w/o Nec
1102 78 10mg/m3 32 96.3 127.9 152.3 167.2 175.7 Terminal Sacrifice
1103 78 10mg/m3 32 118.1 151.8 176.2 193 205.6 Terminal Sacrifice
1104 78 10mg/m3 32 98.3 137.7 164.9 183.9 196.8 Terminal Sacrifice
1105 78 10mg/m3 31 104 138.2 159.9 169.8 168.6 SSAC w/o Nec
1106 79 10mg/m3 73 105 135.1 154.9 165.3 205.2 SSAC w/o Nec
1107 79 10mg/m3 32 97.9 135.6 162.4 182.6 190.8 Terminal Sacrifice
1108 79 10mg/m3 32 101.6 138.9 165.7 176.4 188.7 Terminal Sacrifice
1109 79 10mg/m3 157 115.7 147 173 190.2 267.4 SSAC w/o Nec
1110 79 10mg/m3 45 107.4 142.8 168.7 193.6 220.6 SSAC w/o Nec
1111 80 10mg/m3 157 106.8 140.9 169 190.1 271.3 SSAC w/o Nec
1112 80 10mg/m3 31 116.1 151.2 179.2 194.2 192.5 SSAC w/o Nec
1113 80 10mg/m3 32 104.1 136.2 159.9 175.8 184.5 Terminal Sacrifice
1114 80 10mg/m3 31 106.8 146.6 177.9 195.6 198 SSAC w/o Nec
1115 80 10mg/m3 45 111.5 157.5 181.4 194.7 213.8 SSAC w/o Nec
1116 81 10mg/m3 31 106.2 140.5 167.7 187.2 187.5 SSAC w/o Nec
1117 81 10mg/m3 31 104 132.2 163.2 182 179.1 SSAC w/o Nec
1118 81 10mg/m3 31 95 126.4 152.3 165.9 163.7 SSAC w/o Nec
1119 81 10mg/m3 73 105 134.9 154.1 171 218.9 SSAC w/o Nec
1120 81 10mg/m3 32 115.4 156.1 188.9 206.4 214.6 Terminal Sacrifice
1121 82 10mg/m3 45 98.8 138.4 169.7 184.4 205.5 SSAC w/o Nec
1122 82 10mg/m3 31 111.4 139.1 165.7 181.4 181 SSAC w/o Nec
1123 82 10mg/m3 45 107.5 141.7 162.6 189.6 209.9 SSAC w/o Nec
1124 82 10mg/m3 32 96.8 132.2 156.6 170.9 185.6 Terminal Sacrifice
1125 82 10mg/m3 157 102.2 133.9 150.2 171 252.4 SSAC w/o Nec
1126 83 10mg/m3 31 106.7 146.1 173.5 193.4 195 SSAC w/o Nec
1127 83 10mg/m3 32 111.7 147.3 175.2 200.4 207.8 Terminal Sacrifice
1128 83 10mg/m3 73 103 138.9 164.5 180.2 220.1 SSAC w/o Nec
1129 83 10mg/m3 31 113.1 141.2 170.9 183.6 185.2 SSAC w/o Nec
1130 83 10mg/m3 157 110.3 147.4 165.6 183.9 256.7 SSAC w/o Nec
1131 84 10mg/m3 157 107.2 147.3 174.9 192.6 271.1 SSAC w/o Nec
1132 84 10mg/m3 45 101.4 130.6 146.7 161.1 183.7 SSAC w/o Nec
1133 84 10mg/m3 32 95.7 133.2 160.8 174.9 186.2 Terminal Sacrifice
1134 84 10mg/m3 31 120.4 157.6 189.8 208.5 205.3 SSAC w/o Nec
1135 84 10mg/m3 73 105.8 142.1 169.2 179.4 217.1 SSAC w/o Nec
* All body weights in grams