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Long-Term Study Organ Weights Individual Animal

Study Information:

Chemical Name: Perfluorooctanoic Acid
CASRN: ="335-67-1"
Study Number: C20614
Study Length (Year Completed): (N/A)
Exposure Route: DOSED FEED
TDMS Number: 2061401
Sex: Female
Strain and Species: HSD Rats

Organ Weights Individual Animal Data
Measurement Time Animal Number Dose Group (ppm) Control Code Final Body Weight (g)
Day 66 484 1000 7.4
Day 109 302 0 266.6
Day 109 305 0 269.8
Day 109 308 0 231.5
Day 109 312 0 277.9
Day 109 319 0 260.6
Day 109 332 0 258
Day 109 334 0 249.3
Day 109 339 0 247
Day 109 341 0 239.8
Day 109 346 0 251.7
Day 109 428 150 223.1
Day 109 429 150 229.2
Day 109 435 150 246.4
Day 109 436 150 257.3
Day 109 442 150 225.3
Day 109 444 150 216.9
Day 109 446 150 248.3
Day 109 451 150 233.7
Day 109 456 150 249.9
Day 109 468 150 293.3
Day 109 361 300 241.8
Day 109 365 300 246.5
Day 109 366 300 231.1
Day 109 367 300 276
Day 109 371 300 222.7
Day 109 382 300 229.1
Day 109 385 300 273.8
Day 109 405 300 230.9
Day 109 406 300 232.9
Day 109 409 300 304.5
Day 109 541 300 236
Day 109 562 300 220.1
Day 109 565 300 250.3
Day 109 571 300 254.2
Day 109 577 300 197.8
Day 109 581 300 200.5
Day 109 583 300 268.4
Day 109 593 300 198.2
Day 109 595 300 207
Day 109 600 300 201.6
Day 109 491 1000 213.6
Day 109 494 1000 226.3
Day 109 499 1000 204.8
Day 109 501 1000 222.4
Day 109 511 1000 244.4
Day 109 514 1000 223.1
Day 109 519 1000 228.3
Day 109 530 1000 237.6
Day 109 531 1000 228.3
Day 109 534 1000 207.7
Day 183 574 300 130.5
Day 225 532 1000 140.8
Day 250 390 300 294.2
Day 253 492 1000 158.6
Day 274 347 0 230
Day 284 520 1000 143.3
Day 295 432 150 316.3
Day 298 488 1000 158.8
Day 312 345 0 442
Day 322 421 150 261.1
Day 323 343 0 252.3
Day 349 474 150 291.4
Day 351 459 150 354.8
Day 351 517 1000 148.8
Day 368 473 150 576.4
Day 379 507 1000 270.2
Day 382 348 0 263.4
Day 391 575 300 192.3
Day 393 585 300 154.5
Day 411 359 0 323.8
Day 435 304 0 727.5
Day 438 497 1000 238.2
Day 440 588 300 156.3
Day 452 330 0 264.3
Day 454 557 300 148.9
Day 457 576 300 135.6
Day 470 374 300 472.9
Day 470 383 300 467.3
Day 472 551 300 222.8
Day 484 379 300 445.5
Day 484 510 1000 340.2
Day 491 591 300 339.2
Day 505 486 1000 251.9
Day 508 572 300 186.8
Day 522 527 1000 244.3
Day 533 311 0 266.3
Day 533 425 150 358.8
Day 533 447 150 438.1
Day 533 402 300 514
Day 540 533 1000 528.6
Day 543 318 0 310.8
Day 547 329 0 225.5
Day 564 470 150 205
Day 574 320 0 479.9
Day 574 377 300 372.6
Day 574 384 300 590.5
Day 574 542 300 259.2
Day 575 524 1000 152.3
Day 589 326 0 318.2
Day 589 452 150 395.5
Day 589 401 300 342
Day 589 546 300 235.1
Day 592 324 0 357.3
Day 617 547 300 175.7
Day 621 331 0 340.9
Day 622 467 150 336.9
Day 624 555 300 209.7
Day 624 556 300 425.7
Day 624 525 1000 419.2
Day 624 540 1000 333.8
Day 625 333 0 268.5
Day 634 426 150 390.3
Day 634 579 300 256
Day 638 354 0 565.5
Day 638 430 150 383.9
Day 638 395 300 599.3
Day 638 587 300 309.5
Day 643 363 300 296.9
Day 645 316 0 427.3
Day 647 328 0 230.3
Day 647 568 300 166.5
Day 652 506 1000 305.7
Day 659 414 300 308
Day 661 355 0 234.6
Day 667 344 0 278
Day 669 490 1000 293.5
Day 669 526 1000 263.3
Day 673 351 0 363
Day 673 550 300 134.1
Day 673 561 300 467.7
Day 673 567 300 414.1
Day 676 303 0 478.2
Day 676 380 300 232.6
Day 676 597 300 380.4
Day 676 598 300 259
Day 681 553 300 327.9
Day 683 545 300 318.7
Day 687 396 300 304.8
Day 688 360 0 401.8
Day 690 392 300 262.7
Day 690 570 300 376.2
Day 692 338 0 377.2
Day 695 472 150 373.7
Day 695 362 300 170.6
Day 695 378 300 574.8
Day 695 412 300 199.8
Day 695 418 300 370.1
Day 695 582 300 420.4
Day 695 489 1000 272.2
Day 695 509 1000 314.8
Day 705 340 0 410
Day 707 373 300 396.5
Day 712 325 0 261.8
Day 714 461 150 288.7
Day 714 502 1000 320.2
Day 718 422 150 249.2
Day 718 448 150 578.5
Day 718 419 300 532.7
Day 718 559 300 222.3
Day 718 529 1000 368.3
Day 721 516 1000 257.9
Day 722 314 0 300
Day 722 498 1000 238.6
Day 736 518 1000 135.5
Day 737 413 300 337.9
Day 737 500 1000 201.6
Day 739 438 150 222.7
Day 739 416 300 198
Day 741 495 1000 228.6
Day 742 458 150 474.2
Day 744 310 0 344.4
Day 744 315 0 328.1
Day 744 321 0 378.4
Day 744 323 0 354.3
Day 744 336 0 310.9
Day 744 337 0 317.4
Day 744 356 0 326.7
Day 744 357 0 469.4
Day 744 424 150 372.9
Day 744 434 150 336.7
Day 744 437 150 440.7
Day 744 443 150 414.4
Day 744 450 150 301.1
Day 744 455 150 344.2
Day 744 460 150 363.3
Day 744 462 150 353.2
Day 744 469 150 336.6
Day 744 478 150 315.3
Day 744 372 300 342.4
Day 744 381 300 300.9
Day 744 388 300 486.3
Day 744 391 300 392.8
Day 744 394 300 293.1
Day 744 403 300 323.3
Day 744 407 300 331.1
Day 744 410 300 327.2
Day 744 552 300 295.8
Day 744 558 300 299.4
Day 744 563 300 289.3
Day 744 564 300 277.7
Day 744 586 300 231.6
Day 744 589 300 268.3
Day 744 590 300 319.1
Day 744 592 300 349.5
Day 744 594 300 249.2
Day 744 596 300 266.8
Day 744 481 1000 259.5
Day 744 482 1000 332.3
Day 744 483 1000 352
Day 744 485 1000 329.2
Day 744 487 1000 258.2
Day 744 493 1000 285.6
Day 744 536 1000 322.1
Day 744 538 1000 364.8
Day 745 306 0 361.3
Day 745 327 0 345.3
Day 745 335 0 432.3
Day 745 349 0 582.2
Day 745 353 0 401.9
Day 745 431 150 301.3
Day 745 439 150 373
Day 745 441 150 213.5
Day 745 445 150 279.4
Day 745 449 150 292.5
Day 745 453 150 383.9
Day 745 457 150 382.1
Day 745 466 150 403
Day 745 475 150 273.9
Day 745 476 150 250.8
Day 745 479 150 323.3
Day 745 364 300 400.6
Day 745 368 300 406.5
Day 745 375 300 358.6
Day 745 376 300 383.4
Day 745 386 300 394.9
Day 745 389 300 358.1
Day 745 393 300 368.5
Day 745 398 300 384.7
Day 745 411 300 334.2
Day 745 415 300 288.6
Day 745 420 300 486.1
Day 745 548 300 248.3
Day 745 549 300 327.2
Day 745 554 300 344.6
Day 745 566 300 307.3
Day 745 569 300 279.9
Day 745 584 300 336
Day 745 599 300 279.4
Day 745 496 1000 256.2
Day 745 503 1000 268.7
Day 745 504 1000 394.6
Day 745 505 1000 313.9
Day 745 508 1000 356
Day 745 512 1000 343.9
Day 745 515 1000 310.2
Day 745 521 1000 257.7
Day 745 522 1000 260.9
Day 746 301 0 347.2
Day 746 307 0 332.9
Day 746 309 0 435.5
Day 746 313 0 332.1
Day 746 317 0 424.2
Day 746 322 0 386.9
Day 746 342 0 517.2
Day 746 350 0 324.9
Day 746 352 0 562.3
Day 746 358 0 334.9
Day 746 423 150 318.2
Day 746 427 150 294.5
Day 746 433 150 313.8
Day 746 440 150 336.7
Day 746 454 150 310.9
Day 746 463 150 427
Day 746 464 150 322.6
Day 746 465 150 492.2
Day 746 471 150 433.3
Day 746 477 150 447.7
Day 746 480 150 339.6
Day 746 369 300 467.8
Day 746 370 300 353.9
Day 746 387 300 393.1
Day 746 397 300 383
Day 746 399 300 325.8
Day 746 400 300 373.2
Day 746 404 300 500.7
Day 746 408 300 349.8
Day 746 417 300 264.6
Day 746 543 300 250.1
Day 746 544 300 271
Day 746 560 300 291.5
Day 746 573 300 271.2
Day 746 578 300 237.4
Day 746 580 300 273.9
Day 746 513 1000 284.9
Day 746 523 1000 272.2
Day 746 528 1000 293.6
Day 746 535 1000 304.1
Day 746 537 1000 300.9
Day 746 539 1000 473.7
Abbreviations:
NA: Not Available