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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: Ionic Liquid: 1-Butyl-1-methylpyrrolidinium Chloride
CASRN: ="479500-35-1"
Study Number: C05051
Exposure Route: DOSED WATER
TDMS Number: 5005101
Sex: Male
Strain and Species: HSD Rats

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Vehicle Control 10 66 502 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 67 506 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Alimentary System Liver 3 mg/mL 10 81 540 92 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Alimentary System Liver 0.3 mg/mL 1 71 514 92 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 66 502 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 67 506 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver 3 mg/mL 10 79 535 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver 3 mg/mL 10 79 536 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Pancreas Acinus 3 mg/mL 10 79 534 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Pancreas Vehicle Control 10 69 510 92 1 Atrophy Minimal, Focal Terminal Sacrifice
Alimentary System Stomach, Glandular Vehicle Control 10 66 501 92 1 Cyst Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Vehicle Control 10 66 501 92 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Islets Pancreatic Vehicle Control 10 67 505 92 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Islets Pancreatic Vehicle Control 10 69 509 92 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Islets Pancreatic 3 mg/mL 10 78 532 92 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Islets Pancreatic 3 mg/mL 10 80 538 92 1 Hyperplasia Minimal Terminal Sacrifice
Hematopoietic System Thymus 3 mg/mL 10 78 531 92 1 Hemorrhage Minimal Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 66 502 92 1 Infiltration Cellular Minimal, Histiocyte Terminal Sacrifice
Respiratory System Lung 3 mg/mL 10 80 538 92 1 Infiltration Cellular Minimal, Histiocyte Terminal Sacrifice
Respiratory System Lung 3 mg/mL 10 78 532 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Respiratory System Lung 3 mg/mL 10 78 533 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Special Senses System Eye Retina Vehicle Control 10 69 510 92 1 Dysplasia Minimal Terminal Sacrifice
Special Senses System Harderian Gland Vehicle Control 10 66 503 92 1 Inflammation Minimal Terminal Sacrifice
Urinary System Kidney Pelvis 0.3 mg/mL 1 71 514 92 1 Dilatation Mild Terminal Sacrifice
Urinary System Kidney Pelvis 0.3 mg/mL 1 71 514 92 1 Inflammation Moderate Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 66 501 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 66 502 92 1 Nephropathy Mild Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 66 503 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 67 504 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 67 505 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 67 506 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 68 508 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 69 509 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 69 510 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 mg/mL 10 78 531 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 mg/mL 10 78 533 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 mg/mL 10 79 534 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 mg/mL 10 79 535 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 mg/mL 10 79 536 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 mg/mL 10 80 537 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 mg/mL 10 80 538 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 mg/mL 10 81 539 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 mg/mL 10 81 540 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Ureter 0.3 mg/mL 1 71 514 92 1 Inflammation Mild Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 0.3 mg/mL 1 71 514 92 1 Hyperplasia Moderate Terminal Sacrifice
Urinary System Urinary Bladder 0.3 mg/mL 1 71 514 92 1 Calculus Gross Observation Terminal Sacrifice
Urinary System Urinary Bladder 0.3 mg/mL 1 71 514 92 1 Inflammation Mild Terminal Sacrifice