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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: Ionic Liquid: 1-Butyl-1-methylpyrrolidinium Chloride
CASRN: ="479500-35-1"
Study Number: C05051
Exposure Route: DOSED WATER
TDMS Number: 5005102
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Vehicle Control 10 10 410 92 1 Infiltration Cellular Minimal, Mononuclear Cl Terminal Sacrifice
Cardiovascular System Heart Valve 10 mg/mL 10 38 438 92 1 Pigmentation Mild, Melanin Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 3 403 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 8 408 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart 10 mg/mL 10 39 439 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex 10 mg/mL 10 32 432 92 1 Hypertrophy Minimal Terminal Sacrifice
Endocrine System Adrenal Medulla 10 mg/mL 10 39 439 92 1 Hyperplasia Minimal Terminal Sacrifice
Respiratory System Lung Alveolus Vehicle Control 10 5 405 92 1 Infiltration Cellular Minimal, Histiocyte Terminal Sacrifice
Urinary System Kidney Renal Tubule 10 mg/mL 10 35 435 92 1 Necrosis Moderate Terminal Sacrifice
Urinary System Kidney Transit Epithe Vehicle Control 10 3 403 92 1 Karyomegaly Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 10 mg/mL 10 33 433 92 1 Nuclear Alteration Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 10 mg/mL 10 38 438 92 1 Nuclear Alteration Minimal Terminal Sacrifice