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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: Ionic Liquid: 1-Ethyl-3-methylimidazolium Chloride
CASRN: ="65039-09-0"
Study Number: C07018
Exposure Route: DOSED WATER
TDMS Number: 0701801
Sex: Male
Strain and Species: HSD Rats

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Vehicle Control 10 67 306 92 1 Infiltration Cellular Minimal, Mixed Cell Terminal Sacrifice
Alimentary System Liver 10 mg/mL 10 78 333 92 1 Infiltration Cellular Minimal, Mixed Cell Terminal Sacrifice
Alimentary System Liver 10 mg/mL 10 79 336 92 1 Infiltration Cellular Minimal, Mixed Cell Terminal Sacrifice
Alimentary System Pancreas Acinus Vehicle Control 10 66 302 92 1 Atrophy Minimal Terminal Sacrifice
Alimentary System Stomach, Glandular Epithelium Vehicle Control 10 67 304 92 1 Degeneration Minimal Terminal Sacrifice
Alimentary System Stomach, Glandular 10 mg/mL 10 79 334 92 1 Mineralization Minimal Terminal Sacrifice
Alimentary System Stomach, Glandular 10 mg/mL 10 79 335 92 1 Mineralization Minimal Terminal Sacrifice
Alimentary System Stomach, Glandular 10 mg/mL 10 80 338 92 1 Mineralization Minimal Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 66 302 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart 10 mg/mL 10 78 332 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart 10 mg/mL 10 78 333 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 10 69 309 92 1 Cyst Minimal Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 10 mg/mL 10 79 336 92 1 Cyst Minimal Terminal Sacrifice
Hematopoietic System Bone Marrow Vehicle Control 10 66 301 92 1 Hyperplasia Minimal Terminal Sacrifice
Hematopoietic System Bone Marrow Vehicle Control 10 67 305 92 1 Hyperplasia Minimal Terminal Sacrifice
Hematopoietic System Thymus 10 mg/mL 10 79 336 92 1 Atrophy Minimal Terminal Sacrifice
Hematopoietic System Thymus 10 mg/mL 10 80 337 92 1 Atrophy Minimal Terminal Sacrifice
Hematopoietic System Thymus 10 mg/mL 10 81 339 92 1 Atrophy Minimal Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 67 305 92 1 Infiltration Cellular Minimal, Histiocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 68 308 92 1 Infiltration Cellular Minimal, Histiocyte Terminal Sacrifice
Respiratory System Nose Olfactory Epi Vehicle Control 10 66 302 92 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi Vehicle Control 10 67 304 92 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi Vehicle Control 10 68 308 92 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi Vehicle Control 10 69 310 92 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10 mg/mL 10 78 332 92 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10 mg/mL 10 78 333 92 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10 mg/mL 10 80 337 92 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10 mg/mL 10 80 338 92 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10 mg/mL 10 81 340 92 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Special Senses System Harderian Gland Vehicle Control 10 66 302 92 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 66 301 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 66 302 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 66 303 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 67 304 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 67 305 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 68 307 92 1 Nephropathy Mild Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 68 308 92 1 Nephropathy Mild Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 69 309 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 69 310 92 1 Nephropathy Mild Terminal Sacrifice
Urinary System Kidney 10 mg/mL 10 78 331 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 10 mg/mL 10 78 332 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 10 mg/mL 10 78 333 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 10 mg/mL 10 79 334 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 10 mg/mL 10 79 335 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 10 mg/mL 10 79 336 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 10 mg/mL 10 80 337 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 10 mg/mL 10 80 338 92 1 Nephropathy Minimal Terminal Sacrifice