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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: Ionic Liquid: 1-Ethyl-3-methylimidazolium Chloride
CASRN: ="65039-09-0"
Study Number: C07018
Exposure Route: DOSED WATER
TDMS Number: 0701802
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver 30 mg/mL 10 37 237 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Alimentary System Liver 30 mg/mL 10 40 240 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Stomach, Forestomach Epithelium 10 mg/mL 1 28 228 92 1 Cyst Moderate Terminal Sacrifice
Endocrine System Adrenal Cortex Subcapsular 30 mg/mL 10 40 240 92 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Islets Pancreatic Vehicle Control 10 7 207 92 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Thyroid Gland Vehicle Control 10 10 210 92 1 Cyst Minimal Terminal Sacrifice
Genital System Preputial Gland 30 mg/mL 10 37 237 92 1 Atrophy Mild Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 10 7 207 92 1 Hyperplasia Minimal, Lymphoid Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 30 mg/mL 10 38 238 92 1 Hyperplasia Minimal, Lymphoid Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 30 mg/mL 10 39 239 92 1 Hyperplasia Minimal, Lymphoid Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 30 mg/mL 10 40 240 92 1 Hyperplasia Minimal, Lymphoid Terminal Sacrifice
Hematopoietic System Spleen Lymph Follic Vehicle Control 10 2 202 92 1 Hyperplasia Minimal Terminal Sacrifice
Hematopoietic System Spleen Lymph Follic Vehicle Control 10 4 204 92 1 Hyperplasia Minimal Terminal Sacrifice
Hematopoietic System Spleen Lymph Follic Vehicle Control 10 7 207 92 1 Hyperplasia Minimal Terminal Sacrifice
Hematopoietic System Spleen Lymph Follic 30 mg/mL 10 37 237 92 1 Hyperplasia Minimal Terminal Sacrifice
Hematopoietic System Spleen Lymph Follic 30 mg/mL 10 38 238 92 1 Hyperplasia Minimal Terminal Sacrifice
Hematopoietic System Spleen Vehicle Control 10 2 202 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 30 mg/mL 10 31 231 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Thymus Vehicle Control 10 10 210 92 1 Atrophy Minimal Terminal Sacrifice
Hematopoietic System Thymus 30 mg/mL 10 33 233 92 1 Atrophy Minimal Terminal Sacrifice
Hematopoietic System Thymus 30 mg/mL 10 37 237 92 1 Atrophy Mild Terminal Sacrifice
Urinary System Kidney 30 mg/mL 10 31 231 92 1 Infarct Minimal Terminal Sacrifice
Urinary System Kidney 30 mg/mL 10 40 240 92 1 Infarct Minimal Terminal Sacrifice
Urinary System Kidney 10 mg/mL 10 25 225 92 1 Infiltration Cellular Minimal, Mononuclear Cl Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 6 206 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 mg/mL 10 16 216 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 10 mg/mL 10 22 222 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 10 mg/mL 10 26 226 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 10 mg/mL 10 27 227 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 30 mg/mL 10 31 231 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 30 mg/mL 10 32 232 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 30 mg/mL 10 34 234 92 1 Nephropathy Mild Terminal Sacrifice
Urinary System Kidney 30 mg/mL 10 35 235 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 30 mg/mL 10 36 236 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 30 mg/mL 10 37 237 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 30 mg/mL 10 38 238 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 30 mg/mL 10 40 240 92 1 Nephropathy Minimal Terminal Sacrifice