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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: Ionic Liquid: N-Butylpyridinium Chloride
CASRN: ="1124-64-7"
Study Number: C05052
Exposure Route: DOSED WATER
TDMS Number: 5005201
Sex: Female
Strain and Species: HSD Rats

Female Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Intestine Small Jejunum, Peyers Patch 3 mg/mL 10 89 779 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Liver 3 mg/mL 10 89 776 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Alimentary System Liver 3 mg/mL 10 89 777 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 83 750 92 1 Infiltration Cellular Minimal, Mixed Cell Terminal Sacrifice
Alimentary System Liver 3 mg/mL 10 88 772 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Alimentary System Liver 3 mg/mL 10 89 778 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 82 745 92 1 Pigmentation Minimal, Bile Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 83 747 92 1 Pigmentation Minimal, Bile Terminal Sacrifice
Alimentary System Stomach, Glandular Vehicle Control 10 82 744 92 1 Mineralization Minimal Terminal Sacrifice
Genital System Uterus Endometrium 3 mg/mL 10 89 779 92 1 Hyperplasia Minimal, Cystic Terminal Sacrifice
Genital System Uterus 1 mg/mL 1 86 764 92 1 Dilatation Minimal Terminal Sacrifice
Genital System Uterus 3 mg/mL 10 88 771 92 1 Dilatation Minimal Terminal Sacrifice
Genital System Uterus Vehicle Control 10 82 742 92 1 Inflammation Minimal Terminal Sacrifice
Hematopoietic System Spleen 0.3 mg/mL 1 84 753 92 1 Atrophy Marked Terminal Sacrifice
Hematopoietic System Spleen 0.3 mg/mL 1 84 753 92 1 Fibrosis Moderate Terminal Sacrifice
Hematopoietic System Spleen 3 mg/mL 10 89 779 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 3 mg/mL 10 89 780 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen Vehicle Control 10 82 741 92 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen Vehicle Control 10 82 742 92 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen Vehicle Control 10 82 743 92 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen Vehicle Control 10 82 744 92 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen Vehicle Control 10 82 745 92 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen Vehicle Control 10 83 746 92 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen Vehicle Control 10 83 747 92 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen Vehicle Control 10 83 748 92 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen Vehicle Control 10 83 749 92 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen Vehicle Control 10 83 750 92 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 0.3 mg/mL 1 84 753 92 1 Pigmentation Moderate, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 3 mg/mL 10 88 771 92 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 3 mg/mL 10 88 772 92 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 3 mg/mL 10 88 773 92 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 3 mg/mL 10 88 774 92 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 3 mg/mL 10 88 775 92 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 3 mg/mL 10 89 776 92 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 3 mg/mL 10 89 777 92 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 3 mg/mL 10 89 778 92 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 3 mg/mL 10 89 779 92 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Hematopoietic System Spleen 3 mg/mL 10 89 780 92 1 Pigmentation Minimal, Hemosiderin Terminal Sacrifice
Respiratory System Lung 3 mg/mL 10 89 778 92 1 Infiltration Cellular Minimal, Histiocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 82 741 92 1 Inflammation Minimal Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 83 746 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Respiratory System Nose Olfactory Epi Vehicle Control 10 82 741 92 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi Vehicle Control 10 82 745 92 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi Vehicle Control 10 83 749 92 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi Vehicle Control 10 83 750 92 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 3 mg/mL 10 88 771 92 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 3 mg/mL 10 88 772 92 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 3 mg/mL 10 88 773 92 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 3 mg/mL 10 88 775 92 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 3 mg/mL 10 89 777 92 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 3 mg/mL 10 89 778 92 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 3 mg/mL 10 89 779 92 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Respiratory System Nose Respirat Epith Vehicle Control 10 82 741 92 1 Inflammation Minimal Terminal Sacrifice
Respiratory System Nose Respirat Epith Vehicle Control 10 82 742 92 1 Inflammation Mild Terminal Sacrifice
Respiratory System Nose Respirat Epith Vehicle Control 10 82 743 92 1 Inflammation Minimal Terminal Sacrifice
Respiratory System Nose Respirat Epith Vehicle Control 10 82 744 92 1 Inflammation Minimal Terminal Sacrifice
Respiratory System Nose Respirat Epith Vehicle Control 10 82 745 92 1 Inflammation Mild Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 82 741 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 82 744 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 83 747 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 mg/mL 10 88 773 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 mg/mL 10 88 774 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 mg/mL 10 89 776 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 mg/mL 10 89 779 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 mg/mL 10 89 780 92 1 Nephropathy Minimal Terminal Sacrifice