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Short-Term Study Body Weights

Study Information:

Chemical Name: Tetrabromobisphenol A-bis(2,3-dibromopropyl ether)
CASRN: ="21850-44-2"
Study Number: C20321
Exposure Route: GAVAGE
TDMS Number: 2032101
Sex: Male
Strain and Species: F344/N Tac Rats

Animal Number Cage Number Dose Group Days On Study Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 14 Removal Reason
1 1 Vehicle Control 93 118.1 150.2 177.5 196.2 214.2 233 243.3 252.6 262.3 266.6 276.9 285 294.4 Terminal Sacrifice
2 1 Vehicle Control 93 96.7 124.4 161.6 191.5 218.6 240.2 253 265.3 276.6 288.5 302.5 312.6 330.9 Terminal Sacrifice
3 1 Vehicle Control 93 109.9 137.3 169.9 196.8 221.2 240.6 247.7 256.3 270.1 283.6 295.4 304.5 316.7 Terminal Sacrifice
4 1 Vehicle Control 93 114.4 145.3 172.2 194.8 221.6 240.2 254.6 268.5 276.9 289.1 303.9 306.9 326.2 Terminal Sacrifice
5 1 Vehicle Control 93 114.2 147.6 185 213.7 240.6 263.1 279.2 291.3 304.1 320.4 330.6 337.8 356.8 Terminal Sacrifice
6 2 Vehicle Control 93 119.3 151.9 184.1 209.1 234 255.5 272.8 285.7 301.8 316.7 326 334.5 350.9 Terminal Sacrifice
7 2 Vehicle Control 93 117.3 154.2 191.8 221.5 251.5 274.6 293.1 312.1 325.9 340.6 351.1 360.2 371.2 Terminal Sacrifice
8 2 Vehicle Control 93 108 133.9 159.5 178.9 199.4 214.2 226.3 242.1 257.1 259.3 267.5 271.9 286.4 Terminal Sacrifice
9 2 Vehicle Control 93 128.4 158.7 192 216.4 237.3 258.2 271.9 284.9 299.9 316.5 320.1 331.2 345.9 Terminal Sacrifice
10 2 Vehicle Control 93 98.8 129.5 160.2 183.3 207.6 223.8 240.9 255.2 267.1 277.7 289.5 299.7 316.1 Terminal Sacrifice
11 3 62.5mg/kg 93 120.8 150.1 181.5 203 221.7 241.5 257.3 268.6 281.6 290.4 302.9 309.9 326.6 Terminal Sacrifice
12 3 62.5mg/kg 40 105.2 136.5 171.5 192.1 216.6 228.1 Dosing Accident
13 3 62.5mg/kg 93 123.6 160.1 195.2 224.3 249.2 274.3 294.7 314.4 326.5 343.3 357.2 368.4 386.5 Terminal Sacrifice
14 3 62.5mg/kg 37 113.1 146 180 211 234.5 235.8 Natural Death
15 3 62.5mg/kg 93 115.3 145.2 174.7 195.1 214.6 233.6 247 259.8 274 280.5 299.8 308.2 330.8 Terminal Sacrifice
16 4 62.5mg/kg 93 114.3 144 170.7 192.1 212.3 230.8 244.9 264.2 276.3 282.7 293.1 300 311 Terminal Sacrifice
17 4 62.5mg/kg 93 112.6 143.5 178.7 206.4 229.9 251 275.2 293.3 307.1 322.4 335.9 344.2 365.5 Terminal Sacrifice
18 4 62.5mg/kg 93 111.1 142 175.9 205.9 229.5 251.2 270.9 288.6 302.1 313 323.1 339.5 351.1 Terminal Sacrifice
19 4 62.5mg/kg 93 103.9 136.4 168.9 197 222.8 245.9 260.7 275 290.4 299.9 308.5 316.2 334.1 Terminal Sacrifice
20 4 62.5mg/kg 93 112.7 145.1 178.7 205.8 229.9 250.7 269.1 282.9 297.6 308.9 326.9 335.4 347.1 Terminal Sacrifice
21 5 125mg/kg 93 107.3 135.4 162.3 180.5 203.8 223.8 236.6 251.1 266.2 270.2 281.5 286.1 300.4 Terminal Sacrifice
22 5 125mg/kg 93 99 126.5 155.7 177.3 199.8 220.1 234.2 245.8 256.4 265.4 278.4 286.3 301.4 Terminal Sacrifice
23 5 125mg/kg 93 112 144.8 179.4 207.2 233.4 251.4 270.2 287.7 301.2 308.3 326.3 335.1 353.4 Terminal Sacrifice
24 5 125mg/kg 93 117.3 152.3 184.8 209 234.5 255.3 271.2 288.9 307.5 318.1 336 343.2 360.8 Terminal Sacrifice
25 5 125mg/kg 93 118.6 147.4 175.7 196.3 220.1 236 248.9 260 274.8 282.9 295.1 297.1 310.5 Terminal Sacrifice
26 6 125mg/kg 93 112.1 146.8 178.7 201.4 222.3 240.6 257.5 274 285.1 300.2 309.1 317.2 338.1 Terminal Sacrifice
27 6 125mg/kg 93 104.7 136.7 169.1 197 220.9 245.1 262 278.7 294.1 304.5 320.5 328.2 345.6 Terminal Sacrifice
28 6 125mg/kg 93 118.4 150.3 178.8 198.5 221.5 240.2 257.3 273.4 281 289 305 310.8 326.3 Terminal Sacrifice
29 6 125mg/kg 93 98.9 132.9 167.4 191 212.8 233.3 250.3 267.1 281.1 292.4 305.7 313.3 325.5 Terminal Sacrifice
30 6 125mg/kg 93 108 139.2 173.2 196.1 218.7 238.3 256.2 271.4 287.8 297.8 306.4 314.3 330.7 Terminal Sacrifice
31 7 250mg/kg 93 109.9 144 176.4 204 228.1 248.9 265.1 280 291.8 306.3 322 332.1 348.4 Terminal Sacrifice
32 7 250mg/kg 93 113.6 145.7 179.6 208.7 230.3 253 269 285.6 303.7 315.6 332 339.9 361.2 Terminal Sacrifice
33 7 250mg/kg 93 109.7 142 177.4 202.7 229 248.7 265.4 282.4 298.3 311.2 327.4 332.5 352.6 Terminal Sacrifice
34 7 250mg/kg 93 122.8 154 183.4 206.6 229.2 248.2 262.6 281.3 293.5 305.2 313.7 324.6 339 Terminal Sacrifice
35 7 250mg/kg 93 109.5 135.5 167.1 189.2 209.7 227.9 238.5 250.7 264.2 277.3 289.5 294.6 316.3 Terminal Sacrifice
36 8 250mg/kg 93 103.6 136.1 168.6 196.7 221.6 246.7 265.1 282.4 295 307.7 319.1 326.7 344.7 Terminal Sacrifice
37 8 250mg/kg 93 101.3 137.6 172.8 201.5 228.8 250.4 269.9 285 301.5 309.3 324.6 327 339.6 Terminal Sacrifice
38 8 250mg/kg 93 114.6 147.9 177.9 200.7 223.7 246.6 263.1 281.2 295 307.5 316.1 317.9 336.3 Terminal Sacrifice
39 8 250mg/kg 93 119.9 157.8 195.4 219.7 242.6 264.9 281 302.1 318.6 327.6 339.9 345.3 365.4 Terminal Sacrifice
40 8 250mg/kg 93 117.4 144 170 190.9 213.9 235.1 226.7 249.8 269.7 281.7 296 296.5 311.5 Terminal Sacrifice
41 9 500mg/kg 93 103.9 137.9 175.5 206 231 255 270.5 289.6 308.2 321.4 336.7 346.6 355.7 Terminal Sacrifice
42 9 500mg/kg 93 101.9 128.2 156.3 179.3 200.1 216.3 234.5 250.7 268.1 279 288.9 301.7 311.3 Terminal Sacrifice
43 9 500mg/kg 93 99.2 131.2 165.1 196.9 220.5 237.5 258.7 276 291.6 299.2 312.4 311.9 324.9 Terminal Sacrifice
44 9 500mg/kg 93 120.9 151.1 183.7 207.7 232 253.2 267.1 284.6 301 310.5 326 333.3 345.1 Terminal Sacrifice
45 9 500mg/kg 93 118.4 147.2 179.5 205.8 226.3 240.1 253.1 266.1 276.1 288.9 305.9 310.7 320.9 Terminal Sacrifice
46 10 500mg/kg 93 117.2 152.4 188.4 215.6 239.6 262.1 278.2 291.6 311.6 322.6 328.6 338.5 351.9 Terminal Sacrifice
47 10 500mg/kg 93 116 147.5 177.8 205.7 229.1 245.6 259.3 275.1 288.4 294.4 302.8 310.1 329.4 Terminal Sacrifice
48 10 500mg/kg 93 119.7 150.9 179.2 198.2 222.9 239.1 254.4 265.6 286.3 291.3 299.1 307.8 325.9 Terminal Sacrifice
49 10 500mg/kg 93 116.9 147.9 180.7 203.4 227.2 242.5 259.8 276.6 288.2 292.3 299.1 309.5 314.8 Terminal Sacrifice
50 10 500mg/kg 93 102 137.8 171.6 204.2 232 254.9 274.7 289 300.1 316.4 325.8 335.9 348 Terminal Sacrifice
51 11 1000mg/kg 93 102.1 130.1 158.4 180.5 208.1 225.9 239.7 259.4 270.9 282.4 292.1 304.8 311.5 Terminal Sacrifice
52 11 1000mg/kg 93 120.1 145.5 169.4 185.6 212.1 229.9 244.2 257.7 273.8 284.2 295.2 304.8 318.3 Terminal Sacrifice
53 11 1000mg/kg 93 115.9 145 180.1 204.6 227 249.9 264.4 279.1 293.2 309.6 315.9 321.6 335.2 Terminal Sacrifice
54 11 1000mg/kg 93 113.5 145.1 178.1 201.2 227.4 243.5 257.6 277.8 293.4 299.9 315.6 322.6 338.3 Terminal Sacrifice
55 11 1000mg/kg 93 101.7 131.3 168.6 199.5 224.8 252 272.6 290.5 307.6 320.9 337 349.5 361.9 Terminal Sacrifice
56 12 1000mg/kg 93 110.8 140.4 168.2 190.9 210.1 229 243.8 257.4 272.8 278.9 285.8 294.6 306.4 Terminal Sacrifice
57 12 1000mg/kg 93 100.9 128.6 152.5 170.6 188.8 200.9 213.8 226.8 238.4 248.6 256.8 267.8 285.9 Terminal Sacrifice
58 12 1000mg/kg 93 117.3 146.4 172.6 194.6 212.3 231.9 248.6 261.1 272.3 285.5 297.4 303.7 311.8 Terminal Sacrifice
59 12 1000mg/kg 93 103.1 133.6 158.1 178.4 195.9 210.4 219.5 233.3 245.9 253.7 264.7 275.8 283.1 Terminal Sacrifice
60 12 1000mg/kg 93 115.1 146.9 177.8 203.3 228.3 249 263.8 277.2 294.9 305.6 316.5 327.8 346.6 Terminal Sacrifice
* All body weights in grams