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Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: 2,3-Butanedione
CASRN: ="431-03-8"
Study Number: C20725
Exposure Route: RESPIRATORY EXPOSURE WHOLE BODY
TDMS Number: 2072503
Sex: Female
Strain and Species: Wistar Han Rats

Female Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Intestine Small Ileum 12.5 ppm 50 39 344 687 1 Adenocarcinoma Metastatic Moribund Sacrifice
Alimentary System Intestine Small Jejunum 12.5 ppm 50 34 317 732 1 Leiomyosarcoma Terminal Sacrifice
Alimentary System Liver 12.5 ppm 50 36 328 715 1 Adenocarcinoma Metastatic Moribund Sacrifice
Alimentary System Liver 12.5 ppm 50 39 344 687 1 Adenocarcinoma Metastatic Moribund Sacrifice
Alimentary System Liver 50 ppm 50 80 746 687 1 Adenocarcinoma Metastatic Moribund Sacrifice
Alimentary System Liver Vehicle Control 50 17 132 614 1 Cholangioma Moribund Sacrifice
Alimentary System Liver Vehicle Control 50 15 121 731 1 Cholangioma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 20 148 731 1 Cholangioma Terminal Sacrifice
Alimentary System Liver 12.5 ppm 50 31 303 733 1 Cholangioma Terminal Sacrifice
Alimentary System Liver 12.5 ppm 50 40 346 732 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 25 ppm 50 52 507 733 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 12.5 ppm 50 32 308 630 1 Leukemia Mononuclear Moribund Sacrifice
Alimentary System Liver 50 ppm 50 75 722 435 1 Lymphoma Malignant Moribund Sacrifice
Alimentary System Liver 25 ppm 50 51 501 723 1 Schwannoma Malignant Metastatic Moribund Sacrifice
Alimentary System Mesentery Fat 12.5 ppm 10 35 325 418 1 Schwannoma Malignant Metastatic Moribund Sacrifice
Alimentary System Mesentery 50 ppm 4 80 746 687 1 Adenocarcinoma Metastatic Moribund Sacrifice
Alimentary System Mesentery 12.5 ppm 10 34 320 733 1 Cystadenocarcinoma Metastatic Terminal Sacrifice
Alimentary System Pancreas Acinus 50 ppm 50 80 746 687 1 Adenocarcinoma Metastatic Moribund Sacrifice
Alimentary System Pancreas 12.5 ppm 50 36 328 715 1 Adenocarcinoma Metastatic Moribund Sacrifice
Alimentary System Pancreas 50 ppm 50 76 727 633 1 Schwannoma Malignant Metastatic Moribund Sacrifice
Alimentary System Stomach Forestomach Vehicle Control 50 16 130 731 Multiple Squamous Cell Papilloma Terminal Sacrifice
Alimentary System Stomach Glandular 50 ppm 50 80 746 687 1 Adenocarcinoma Metastatic Moribund Sacrifice
Endocrine System Adrenal Cortex 12.5 ppm 50 36 328 715 1 Adenocarcinoma Metastatic Moribund Sacrifice
Endocrine System Adrenal Cortex 50 ppm 50 80 746 687 1 Adenocarcinoma Metastatic Moribund Sacrifice
Endocrine System Adrenal Cortex Vehicle Control 50 16 129 732 1 Adenoma Terminal Sacrifice
Endocrine System Adrenal Cortex 25 ppm 50 60 547 733 1 Adenoma Terminal Sacrifice
Endocrine System Adrenal Cortex 50 ppm 50 77 731 733 1 Adenoma Terminal Sacrifice
Endocrine System Adrenal Cortex 12.5 ppm 50 32 308 630 1 Leukemia Mononuclear Moribund Sacrifice
Endocrine System Adrenal Cortex 25 ppm 50 51 501 723 1 Schwannoma Malignant Metastatic Moribund Sacrifice
Endocrine System Adrenal Medulla Vehicle Control 50 20 147 599 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla Vehicle Control 50 14 119 733 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Adrenal Medulla Vehicle Control 50 16 126 732 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Adrenal Medulla 50 ppm 50 77 735 711 1 Pheochromocytoma Malignant Natural Death
Endocrine System Parathyroid Gland 25 ppm 50 53 515 732 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 11 104 614 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 12 107 702 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 12 110 547 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 13 112 683 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 14 117 579 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 16 128 417 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 17 134 253 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 17 135 647 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 18 136 561 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 18 140 667 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 20 147 599 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 20 149 687 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 11 102 733 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 11 103 731 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 12 109 732 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 14 120 732 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 15 121 731 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 15 122 731 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 15 123 731 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 15 125 732 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 16 126 732 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 17 131 733 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 18 137 733 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 18 138 732 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 20 148 731 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 20 150 732 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 31 302 661 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 31 304 519 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 31 305 654 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 33 314 603 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 33 315 610 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 35 324 715 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 35 325 418 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 36 328 715 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 36 329 723 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 37 331 603 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 37 335 715 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 38 337 585 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 38 338 718 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 39 344 687 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 39 345 721 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 32 306 732 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 32 307 733 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 32 310 733 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 33 313 731 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 34 318 732 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 35 321 733 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 36 327 731 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 38 340 732 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 12.5 ppm 50 40 349 733 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 51 503 617 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 51 505 724 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 52 508 614 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 53 513 710 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 53 514 452 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 54 518 453 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 54 520 575 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 55 523 695 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 56 527 509 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 57 532 520 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 57 533 361 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 58 536 617 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 58 538 684 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 58 539 515 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 60 550 727 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 53 512 732 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 53 515 732 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 54 516 732 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 55 521 733 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 56 529 732 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 58 537 732 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 59 541 733 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 59 542 731 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 ppm 50 60 546 733 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 50 ppm 50 71 704 544 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 50 ppm 50 72 707 571 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 50 ppm 50 72 708 725 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 50 ppm 50 72 709 633 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 50 ppm 50 73 712 635 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 50 ppm 50 74 716 711 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 50 ppm 50 76 726 697 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 50 ppm 50 78 737 537 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 50 ppm 50 78 739 729 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 50 ppm 50 79 745 642 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 50 ppm 50 80 748 642 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 50 ppm 50 74 720 724 1 Adenoma Natural Death
Endocrine System Pituitary Gland Pars Distalis 50 ppm 50 77 735 711 1 Adenoma Natural Death
Endocrine System Pituitary Gland Pars Distalis 50 ppm 50 71 705 731 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 50 ppm 50 72 710 733 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 50 ppm 50 75 724 732 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 50 ppm 50 77 731 733 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 50 ppm 50 77 732 732 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 50 ppm 50 78 736 731 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 50 ppm 50 79 741 733 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 50 ppm 50 79 742 731 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 50 ppm 50 80 747 733 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 50 ppm 50 80 749 732 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Intermed Vehicle Control 50 11 104 614 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland 50 ppm 50 75 722 435 1 Lymphoma Malignant Moribund Sacrifice
Endocrine System Pituitary Gland 12.5 ppm 50 37 333 137 1 Schwannoma Malignant Metastatic Moribund Sacrifice
Endocrine System Thyroid Gland C Cell Vehicle Control 50 11 102 733 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland C Cell Vehicle Control 50 11 103 731 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland C Cell 12.5 ppm 50 39 344 687 1 Adenoma Moribund Sacrifice
Endocrine System Thyroid Gland C Cell 12.5 ppm 50 31 303 733 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland C Cell 12.5 ppm 50 34 320 733 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland C Cell 12.5 ppm 50 36 330 732 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland C Cell 25 ppm 50 51 501 723 1 Adenoma Moribund Sacrifice
Endocrine System Thyroid Gland C Cell 25 ppm 50 51 505 724 1 Adenoma Moribund Sacrifice
Endocrine System Thyroid Gland C Cell 25 ppm 50 59 543 733 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland C Cell 50 ppm 50 75 723 732 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland C Cell 50 ppm 50 76 730 732 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland C Cell 50 ppm 50 77 732 732 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland C Cell Vehicle Control 50 14 118 733 1 Carcinoma Terminal Sacrifice
Endocrine System Thyroid Gland Follicular Cel Vehicle Control 50 11 104 614 1 Adenoma Moribund Sacrifice
Endocrine System Thyroid Gland Follicular Cel Vehicle Control 50 15 124 733 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland Follicular Cel 12.5 ppm 50 34 316 732 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland Follicular Cel 12.5 ppm 50 34 319 732 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland Follicular Cel 12.5 ppm 50 36 327 731 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland Follicular Cel 12.5 ppm 50 38 339 733 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland Follicular Cel 25 ppm 50 52 506 732 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland Follicular Cel 12.5 ppm 50 33 311 731 1 Carcinoma Terminal Sacrifice
Genital System Ovary Germinal Epith Vehicle Control 50 16 126 732 1 Tubulostromal Adenoma Terminal Sacrifice
Genital System Ovary 50 ppm 50 80 746 687 1 Adenocarcinoma Metastatic Moribund Sacrifice
Genital System Ovary 12.5 ppm 50 34 320 733 1 Cystadenocarcinoma Terminal Sacrifice
Genital System Ovary 12.5 ppm 50 32 307 733 1 Cystadenoma Terminal Sacrifice
Genital System Ovary 12.5 ppm 50 38 338 718 1 Granulosa Cell Tumor Malignant Moribund Sacrifice
Genital System Ovary 25 ppm 50 55 523 695 1 Granulosa Cell Tumor Malignant Moribund Sacrifice
Genital System Ovary 25 ppm 50 57 532 520 1 Granulosa Cell Tumor Malignant Moribund Sacrifice
Genital System Ovary Vehicle Control 50 11 102 733 1 Granulosa-Theca Tumor Malignant Terminal Sacrifice
Genital System Ovary 50 ppm 50 78 737 537 1 Granulosa-Theca Tumor Malignant Moribund Sacrifice
Genital System Ovary 50 ppm 50 80 746 687 1 Sertoli Cell Tumor Benign Moribund Sacrifice
Genital System Ovary 50 ppm 50 79 741 733 1 Sertoli Cell Tumor Benign Terminal Sacrifice
Genital System Ovary 50 ppm 50 78 740 733 1 Thecoma Benign Terminal Sacrifice
Genital System Uterus Cervix 12.5 ppm 50 32 308 630 1 Granular Cell Tumor Benign Moribund Sacrifice
Genital System Uterus Cervix 12.5 ppm 50 32 306 732 1 Granular Cell Tumor Benign Terminal Sacrifice
Genital System Uterus Cervix 12.5 ppm 50 34 316 732 1 Granular Cell Tumor Benign Terminal Sacrifice
Genital System Uterus Cervix 25 ppm 50 59 541 733 1 Hemangioma Terminal Sacrifice
Genital System Uterus Cervix Vehicle Control 50 14 117 579 1 Sarcoma Stromal Moribund Sacrifice
Genital System Uterus Cervix 25 ppm 50 51 502 589 1 Schwannoma Malignant Moribund Sacrifice
Genital System Uterus Cervix 25 ppm 50 51 505 724 1 Squamous Cell Carcinoma Moribund Sacrifice
Genital System Uterus Serosa 12.5 ppm 50 34 320 733 1 Cystadenocarcinoma Metastatic Terminal Sacrifice
Genital System Uterus Vehicle Control 50 12 109 732 1 Adenocarcinoma Terminal Sacrifice
Genital System Uterus Vehicle Control 50 17 133 732 1 Adenocarcinoma Terminal Sacrifice
Genital System Uterus 12.5 ppm 50 36 328 715 1 Adenocarcinoma Moribund Sacrifice
Genital System Uterus 12.5 ppm 50 39 344 687 1 Adenocarcinoma Moribund Sacrifice
Genital System Uterus 12.5 ppm 50 37 332 733 1 Adenocarcinoma Terminal Sacrifice
Genital System Uterus 12.5 ppm 50 39 343 733 1 Adenocarcinoma Terminal Sacrifice
Genital System Uterus 25 ppm 50 52 506 732 1 Adenocarcinoma Terminal Sacrifice
Genital System Uterus 25 ppm 50 59 544 733 1 Adenocarcinoma Terminal Sacrifice
Genital System Uterus 50 ppm 50 74 716 711 1 Adenocarcinoma Moribund Sacrifice
Genital System Uterus 50 ppm 50 80 746 687 1 Adenocarcinoma Moribund Sacrifice
Genital System Uterus 50 ppm 50 71 703 731 1 Adenocarcinoma Terminal Sacrifice
Genital System Uterus 50 ppm 50 73 715 731 1 Adenoma Terminal Sacrifice
Genital System Uterus 50 ppm 50 74 717 733 1 Adenoma Terminal Sacrifice
Genital System Uterus 50 ppm 50 74 718 732 1 Hemangioma Terminal Sacrifice
Genital System Uterus 12.5 ppm 50 31 305 654 1 Leiomyoma Moribund Sacrifice
Genital System Uterus Vehicle Control 50 13 111 710 1 Polyp Stromal Moribund Sacrifice
Genital System Uterus Vehicle Control 50 17 132 614 1 Polyp Stromal Moribund Sacrifice
Genital System Uterus Vehicle Control 50 12 108 635 1 Polyp Stromal Natural Death
Genital System Uterus Vehicle Control 50 12 106 731 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus Vehicle Control 50 14 118 733 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus Vehicle Control 50 14 119 733 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus Vehicle Control 50 15 121 731 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus Vehicle Control 50 18 139 731 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus Vehicle Control 50 19 143 732 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus 12.5 ppm 50 31 305 654 1 Polyp Stromal Moribund Sacrifice
Genital System Uterus 12.5 ppm 50 32 308 630 1 Polyp Stromal Moribund Sacrifice
Genital System Uterus 12.5 ppm 50 33 315 610 1 Polyp Stromal Moribund Sacrifice
Genital System Uterus 12.5 ppm 50 37 331 603 1 Polyp Stromal Moribund Sacrifice
Genital System Uterus 12.5 ppm 50 38 337 585 1 Polyp Stromal Moribund Sacrifice
Genital System Uterus 12.5 ppm 50 38 338 718 Multiple Polyp Stromal Moribund Sacrifice
Genital System Uterus 12.5 ppm 50 39 341 409 1 Polyp Stromal Moribund Sacrifice
Genital System Uterus 12.5 ppm 50 31 303 733 Multiple Polyp Stromal Terminal Sacrifice
Genital System Uterus 12.5 ppm 50 34 319 732 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus 12.5 ppm 50 35 321 733 Multiple Polyp Stromal Terminal Sacrifice
Genital System Uterus 12.5 ppm 50 35 323 732 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus 12.5 ppm 50 38 336 732 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus 12.5 ppm 50 38 340 732 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus 25 ppm 50 51 502 589 1 Polyp Stromal Moribund Sacrifice
Genital System Uterus 25 ppm 50 55 521 733 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus 25 ppm 50 56 528 732 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus 25 ppm 50 58 540 731 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus 25 ppm 50 59 541 733 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus 25 ppm 50 59 544 733 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus 25 ppm 50 60 546 733 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus 50 ppm 50 73 713 491 1 Polyp Stromal Moribund Sacrifice
Genital System Uterus 50 ppm 50 74 716 711 1 Polyp Stromal Moribund Sacrifice
Genital System Uterus 50 ppm 50 76 726 697 1 Polyp Stromal Moribund Sacrifice
Genital System Uterus 50 ppm 50 79 745 642 1 Polyp Stromal Moribund Sacrifice
Genital System Uterus 50 ppm 50 71 705 731 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus 50 ppm 50 74 717 733 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus 50 ppm 50 74 718 732 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus 50 ppm 50 75 724 732 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus 50 ppm 50 75 725 732 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus 50 ppm 50 76 728 731 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus 50 ppm 50 76 729 732 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus 50 ppm 50 77 734 733 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus 50 ppm 50 80 750 732 1 Polyp Stromal Terminal Sacrifice
Genital System Uterus 25 ppm 50 53 511 516 1 Sarcoma Stromal Moribund Sacrifice
Genital System Uterus 25 ppm 50 54 517 628 1 Sarcoma Stromal Moribund Sacrifice
Genital System Uterus 25 ppm 50 55 521 733 1 Sarcoma Stromal Terminal Sacrifice
Genital System Uterus Vehicle Control 50 12 108 635 1 Schwannoma Malignant Natural Death
Genital System Uterus 12.5 ppm 50 35 325 418 1 Schwannoma Malignant Moribund Sacrifice
Genital System Uterus 12.5 ppm 50 36 329 723 1 Schwannoma Malignant Moribund Sacrifice
Genital System Uterus 25 ppm 50 51 501 723 1 Schwannoma Malignant Moribund Sacrifice
Genital System Uterus 25 ppm 50 55 525 528 1 Schwannoma Malignant Moribund Sacrifice
Genital System Uterus 25 ppm 50 57 534 698 1 Schwannoma Malignant Moribund Sacrifice
Genital System Uterus 50 ppm 50 76 727 633 1 Schwannoma Malignant Moribund Sacrifice
Genital System Uterus 50 ppm 50 73 715 731 1 Schwannoma Malignant Terminal Sacrifice
Genital System Vagina 12.5 ppm 1 32 306 732 1 Granular Cell Tumor Benign Terminal Sacrifice
Genital System Vagina 25 ppm 2 57 532 520 1 Polyp Moribund Sacrifice
Genital System Vagina 25 ppm 2 55 525 528 1 Schwannoma Malignant Metastatic Moribund Sacrifice
Hematopoietic System Bone Marrow 50 ppm 50 75 722 435 1 Lymphoma Malignant Moribund Sacrifice
Hematopoietic System Lymph Node Bronchial 50 ppm 50 75 722 435 1 Lymphoma Malignant Moribund Sacrifice
Hematopoietic System Lymph Node Lumbar 12.5 ppm 50 39 343 733 1 Adenocarcinoma Metastatic Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 50 14 120 732 1 Hemangioma Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 50 ppm 50 75 722 435 1 Lymphoma Malignant Moribund Sacrifice
Hematopoietic System Lymph Node Mediastinal 50 ppm 50 80 746 687 1 Adenocarcinoma Metastatic Moribund Sacrifice
Hematopoietic System Lymph Node Mediastinal 50 ppm 50 75 722 435 1 Lymphoma Malignant Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric Vehicle Control 50 11 102 733 1 Hemangiosarcoma Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric Vehicle Control 50 11 103 731 1 Hemangiosarcoma Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 12.5 ppm 50 37 335 715 1 Lymphoma Malignant Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 12.5 ppm 50 35 325 418 1 Schwannoma Malignant Metastatic Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 25 ppm 50 51 502 589 1 Schwannoma Malignant Metastatic Moribund Sacrifice
Hematopoietic System Lymph Node Renal 12.5 ppm 50 39 344 687 1 Adenocarcinoma Metastatic Moribund Sacrifice
Hematopoietic System Lymph Node Renal 12.5 ppm 50 39 343 733 1 Adenocarcinoma Metastatic Terminal Sacrifice
Hematopoietic System Spleen 50 ppm 50 80 746 687 1 Adenocarcinoma Metastatic Moribund Sacrifice
Hematopoietic System Spleen 12.5 ppm 50 32 308 630 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Spleen 50 ppm 50 75 722 435 1 Lymphoma Malignant Moribund Sacrifice
Hematopoietic System Thymus Vehicle Control 50 13 111 710 1 Lymphoma Malignant Moribund Sacrifice
Hematopoietic System Thymus 12.5 ppm 50 37 335 715 1 Lymphoma Malignant Moribund Sacrifice
Hematopoietic System Thymus 25 ppm 50 52 508 614 1 Lymphoma Malignant Moribund Sacrifice
Hematopoietic System Thymus 25 ppm 50 54 519 723 1 Lymphoma Malignant Moribund Sacrifice
Hematopoietic System Thymus 25 ppm 50 59 545 647 1 Lymphoma Malignant Moribund Sacrifice
Integumentary System Mammary Gland Vehicle Control 50 11 104 614 1 Adenoma Moribund Sacrifice
Integumentary System Mammary Gland Vehicle Control 50 17 132 614 Multiple Adenoma Moribund Sacrifice
Integumentary System Mammary Gland Vehicle Control 50 20 149 687 1 Adenoma Moribund Sacrifice
Integumentary System Mammary Gland Vehicle Control 50 11 102 733 1 Adenoma Terminal Sacrifice
Integumentary System Mammary Gland Vehicle Control 50 17 131 733 1 Adenoma Terminal Sacrifice
Integumentary System Mammary Gland 12.5 ppm 50 39 344 687 1 Adenoma Moribund Sacrifice
Integumentary System Mammary Gland 12.5 ppm 50 34 320 733 1 Adenoma Terminal Sacrifice
Integumentary System Mammary Gland 12.5 ppm 50 36 327 731 1 Adenoma Terminal Sacrifice
Integumentary System Mammary Gland 25 ppm 50 56 526 731 1 Adenoma Terminal Sacrifice
Integumentary System Mammary Gland 25 ppm 50 58 537 732 1 Adenoma Terminal Sacrifice
Integumentary System Mammary Gland 50 ppm 50 71 704 544 1 Adenoma Moribund Sacrifice
Integumentary System Mammary Gland Vehicle Control 50 11 104 614 1 Carcinoma Moribund Sacrifice
Integumentary System Mammary Gland Vehicle Control 50 20 147 599 Multiple Carcinoma Moribund Sacrifice
Integumentary System Mammary Gland Vehicle Control 50 15 121 731 1 Carcinoma Terminal Sacrifice
Integumentary System Mammary Gland Vehicle Control 50 18 138 732 Multiple Carcinoma Terminal Sacrifice
Integumentary System Mammary Gland 12.5 ppm 50 35 325 418 1 Carcinoma Moribund Sacrifice
Integumentary System Mammary Gland 12.5 ppm 50 31 303 733 1 Carcinoma Terminal Sacrifice
Integumentary System Mammary Gland 12.5 ppm 50 37 332 733 1 Carcinoma Terminal Sacrifice
Integumentary System Mammary Gland 12.5 ppm 50 39 343 733 1 Carcinoma Terminal Sacrifice
Integumentary System Mammary Gland 25 ppm 50 60 548 732 1 Carcinoma Terminal Sacrifice
Integumentary System Mammary Gland 50 ppm 50 72 707 571 1 Carcinoma Moribund Sacrifice
Integumentary System Mammary Gland 50 ppm 50 72 709 633 1 Carcinoma Moribund Sacrifice
Integumentary System Mammary Gland 50 ppm 50 73 712 635 1 Carcinoma Moribund Sacrifice
Integumentary System Mammary Gland 50 ppm 50 73 713 491 1 Carcinoma Moribund Sacrifice
Integumentary System Mammary Gland 50 ppm 50 74 720 724 Multiple Carcinoma Natural Death
Integumentary System Mammary Gland 50 ppm 50 76 728 731 1 Carcinoma Terminal Sacrifice
Integumentary System Mammary Gland 50 ppm 50 78 736 731 1 Carcinoma Terminal Sacrifice
Integumentary System Mammary Gland 50 ppm 50 78 740 733 1 Carcinoma Terminal Sacrifice
Integumentary System Mammary Gland 50 ppm 50 79 742 731 1 Carcinoma Terminal Sacrifice
Integumentary System Mammary Gland Vehicle Control 50 13 112 683 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary Gland Vehicle Control 50 17 135 647 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary Gland Vehicle Control 50 18 136 561 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary Gland Vehicle Control 50 20 147 599 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary Gland Vehicle Control 50 20 149 687 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary Gland Vehicle Control 50 11 102 733 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland Vehicle Control 50 11 103 731 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland Vehicle Control 50 11 105 733 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland Vehicle Control 50 15 121 731 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland Vehicle Control 50 17 131 733 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland Vehicle Control 50 18 138 732 Multiple Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland Vehicle Control 50 18 139 731 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland Vehicle Control 50 20 150 732 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 12.5 ppm 50 32 308 630 Multiple Fibroadenoma Moribund Sacrifice
Integumentary System Mammary Gland 12.5 ppm 50 31 301 733 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 12.5 ppm 50 31 303 733 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 12.5 ppm 50 32 306 732 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 12.5 ppm 50 33 311 731 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 12.5 ppm 50 33 312 733 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 12.5 ppm 50 33 313 731 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 12.5 ppm 50 36 327 731 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 12.5 ppm 50 36 330 732 Multiple Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 12.5 ppm 50 39 342 732 Multiple Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 12.5 ppm 50 39 343 733 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 12.5 ppm 50 40 349 733 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 12.5 ppm 50 40 350 732 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 25 ppm 50 51 505 724 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary Gland 25 ppm 50 52 510 724 Multiple Fibroadenoma Moribund Sacrifice
Integumentary System Mammary Gland 25 ppm 50 54 519 723 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary Gland 25 ppm 50 55 524 442 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary Gland 25 ppm 50 60 549 723 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary Gland 25 ppm 50 52 506 732 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 25 ppm 50 52 507 733 Multiple Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 25 ppm 50 54 516 732 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 25 ppm 50 56 528 732 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 25 ppm 50 56 529 732 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 25 ppm 50 59 541 733 Multiple Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 25 ppm 50 60 546 733 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 50 ppm 50 71 704 544 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary Gland 50 ppm 50 72 708 725 Multiple Fibroadenoma Moribund Sacrifice
Integumentary System Mammary Gland 50 ppm 50 73 712 635 Multiple Fibroadenoma Moribund Sacrifice
Integumentary System Mammary Gland 50 ppm 50 74 716 711 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary Gland 50 ppm 50 80 748 642 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary Gland 50 ppm 50 74 720 724 1 Fibroadenoma Natural Death
Integumentary System Mammary Gland 50 ppm 50 71 705 731 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 50 ppm 50 75 724 732 Multiple Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 50 ppm 50 76 729 732 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 50 ppm 50 77 731 733 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 50 ppm 50 80 750 732 1 Fibroadenoma Terminal Sacrifice
Integumentary System Skin Subcut Tiss 12.5 ppm 50 39 344 687 1 Adenocarcinoma Metastatic Moribund Sacrifice
Integumentary System Skin Subcut Tiss 50 ppm 50 71 703 731 1 Hibernoma Terminal Sacrifice
Integumentary System Skin Subcut Tiss 50 ppm 50 71 705 731 1 Hibernoma Terminal Sacrifice
Integumentary System Skin Subcut Tiss 12.5 ppm 50 39 345 721 1 Lipoma Moribund Sacrifice
Integumentary System Skin Subcut Tiss 25 ppm 50 52 508 614 1 Lipoma Moribund Sacrifice
Musculoskeletal System Skeletal Muscle 12.5 ppm 7 36 328 715 1 Adenocarcinoma Metastatic Moribund Sacrifice
Musculoskeletal System Skeletal Muscle 12.5 ppm 7 39 344 687 1 Adenocarcinoma Metastatic Moribund Sacrifice
Nervous System Brain Meninges 50 ppm 50 75 722 435 1 Lymphoma Malignant Moribund Sacrifice
Nervous System Brain Vehicle Control 50 16 127 647 1 Granular Cell Tumor Benign Moribund Sacrifice
Nervous System Brain 12.5 ppm 50 38 338 718 1 Granular Cell Tumor Benign Moribund Sacrifice
Nervous System Brain 12.5 ppm 50 32 309 732 1 Granular Cell Tumor Benign Terminal Sacrifice
Nervous System Brain 25 ppm 50 55 521 733 1 Granular Cell Tumor Benign Terminal Sacrifice
Nervous System Brain 50 ppm 50 72 708 725 1 Granular Cell Tumor Benign Moribund Sacrifice
Nervous System Brain Vehicle Control 50 16 130 731 1 Oligodendroglioma Benign Terminal Sacrifice
Nervous System Brain 50 ppm 50 72 707 571 1 Oligodendroglioma Benign Moribund Sacrifice
Nervous System Brain 12.5 ppm 50 37 333 137 1 Schwannoma Malignant Metastatic Moribund Sacrifice
Nervous System Peripheral Nerve Trigeminal 12.5 ppm 6 37 333 137 1 Schwannoma Malignant Metastatic Moribund Sacrifice
Nervous System Peripheral Nerve 50 ppm 5 75 722 435 1 Lymphoma Malignant Moribund Sacrifice
Respiratory System Lung Mediastinum 50 ppm 50 80 746 687 1 Adenocarcinoma Metastatic Moribund Sacrifice
Respiratory System Lung 12.5 ppm 50 39 344 687 1 Adenocarcinoma Metastatic Moribund Sacrifice
Respiratory System Lung 50 ppm 50 74 718 732 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 12.5 ppm 50 32 308 630 1 Leukemia Mononuclear Moribund Sacrifice
Respiratory System Lung 50 ppm 50 76 727 633 1 Schwannoma Malignant Metastatic Moribund Sacrifice
Respiratory System Nose 50 ppm 50 75 722 435 1 Lymphoma Malignant Moribund Sacrifice
Respiratory System Nose 50 ppm 50 74 720 724 1 Squamous Cell Carcinoma Natural Death
Respiratory System Nose 50 ppm 50 71 701 731 1 Squamous Cell Carcinoma Terminal Sacrifice
Respiratory System Nose 50 ppm 50 76 729 732 1 Squamous Cell Carcinoma Terminal Sacrifice
Special Senses System Eye Iris 25 ppm 50 52 510 724 1 Melanoma Malignant Moribund Sacrifice
Special Senses System Eye Optic Nerve 12.5 ppm 50 37 333 137 1 Schwannoma Malignant Metastatic Moribund Sacrifice
Special Senses System Harderian Gland 12.5 ppm 50 37 333 137 1 Schwannoma Malignant Moribund Sacrifice
Urinary System Kidney 50 ppm 50 75 722 435 1 Lymphoma Malignant Moribund Sacrifice
Urinary System Urinary Bladder 25 ppm 50 51 501 723 1 Schwannoma Malignant Metastatic Moribund Sacrifice
Urinary System Urinary Bladder 50 ppm 50 76 727 633 1 Schwannoma Malignant Metastatic Moribund Sacrifice