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Long-Term Study Individual Animal Clinical Observations

Study Information:

Chemical Name: 2-Hydroxy-4-methoxybenzophenone
CASRN: ="131-57-7"
Study Number: C10260
Exposure Route: DOSED FEED
TDMS Number: 1026002
Sex: FEMALE
Strain and Species: B6C3F1/N Mice

Animal Number Dose Group Clinical Observation Qualifier Incident Number Observation Date First Dose Date Days On Study Removal Observation
201 Vehicle Control Ulcer/Abscess Torso/Dorsal 1 05/24/2012 07/15/10 680.00 No
201 Vehicle Control Ulcer/Abscess Torso/Dorsal 1 06/21/2012 07/15/10 708.00 No
201 Vehicle Control Ruffled Fur 07/11/2012 07/15/10 728.00 Yes
201 Vehicle Control Ulcer/Abscess Torso/Dorsal 1 07/11/2012 07/15/10 728.00 Yes
201 Vehicle Control Thin 07/11/2012 07/15/10 728.00 Yes
206 Vehicle Control Thin 02/02/2012 07/15/10 568.00 No
206 Vehicle Control Thin 02/09/2012 07/15/10 575.00 Yes
215 Vehicle Control Thin 04/26/2012 07/15/10 652.00 No
215 Vehicle Control Mass Torso/Lateral, Medium (6mm-15mm) 1 05/24/2012 07/15/10 680.00 No
215 Vehicle Control Thin 05/24/2012 07/15/10 680.00 No
215 Vehicle Control Mass Torso/Dorsal, Small (1mm-5mm) 1 05/24/2012 07/15/10 680.00 No
215 Vehicle Control Mass Torso/Lateral, Large (16mm And Larger) 1 05/26/2012 07/15/10 682.00 Yes
215 Vehicle Control Thin 05/26/2012 07/15/10 682.00 Yes
215 Vehicle Control Mass Torso/Dorsal, Small (1mm-5mm) 1 05/26/2012 07/15/10 682.00 Yes
221 Vehicle Control Mass Torso/Dorsal, Large (16mm And Larger) 1 05/17/2012 07/15/10 673.00 Yes
222 Vehicle Control Thin 05/24/2012 07/15/10 680.00 No
222 Vehicle Control Ruffled Fur 07/10/2012 07/15/10 727.00 Yes
234 Vehicle Control Impaired Gait 05/29/2012 07/15/10 685.00 Yes
234 Vehicle Control Thin 05/29/2012 07/15/10 685.00 Yes
234 Vehicle Control Lethargic 05/29/2012 07/15/10 685.00 Yes
244 Vehicle Control Mass Torso/Lateral, Medium (6mm-15mm) 2 05/24/2012 07/15/10 680.00 No
244 Vehicle Control Mass Torso/Lateral, Medium (6mm-15mm) 1 06/04/2012 07/15/10 691.00 Yes
250 Vehicle Control Ruffled Fur 06/21/2012 07/15/10 708.00 No
251 1000 ppm Eye Abnormality 10/13/2011 07/15/10 456.00 No
251 1000 ppm Eye Abnormality 11/10/2011 07/15/10 484.00 Yes
251 1000 ppm Eye Abnormality 11/10/2011 07/15/10 484.00 No
252 1000 ppm Head Tilt 06/21/2012 07/15/10 708.00 No
252 1000 ppm Head Tilt 07/10/2012 07/15/10 727.00 Yes
256 1000 ppm Eye Abnormality 04/26/2012 07/15/10 652.00 No
256 1000 ppm Eye Abnormality 05/07/2012 07/15/10 663.00 Yes
259 1000 ppm Mass Torso/Ventral, Medium (6mm-15mm) 1 07/10/2012 07/15/10 727.00 Yes
267 1000 ppm Eye Abnormality 11/10/2011 07/15/10 484.00 No
267 1000 ppm Eye Abnormality 12/08/2011 07/15/10 512.00 No
267 1000 ppm Eye Abnormality 01/05/2012 07/15/10 540.00 No
267 1000 ppm Mass Head, Medium (6mm-15mm) 1 02/02/2012 07/15/10 568.00 No
267 1000 ppm Eye Abnormality 02/02/2012 07/15/10 568.00 No
267 1000 ppm Mass Head, Medium (6mm-15mm) 1 03/01/2012 07/15/10 596.00 No
267 1000 ppm Eye Abnormality 03/01/2012 07/15/10 596.00 No
267 1000 ppm Eye Abnormality 03/07/2012 07/15/10 602.00 Yes
267 1000 ppm Mass Head, Medium (6mm-15mm) 1 03/07/2012 07/15/10 602.00 Yes
269 1000 ppm Mass Torso/Lateral, Small (1mm-5mm) 1 05/24/2012 07/15/10 680.00 No
269 1000 ppm Mass Torso/Ventral, Large (16mm And Larger) 1 06/21/2012 07/15/10 708.00 No
269 1000 ppm Mass Torso/Ventral, Large (16mm And Larger) 1 07/09/2012 07/15/10 726.00 Yes
269 1000 ppm Thin 07/09/2012 07/15/10 726.00 Yes
271 1000 ppm Mass Torso/Dorsal, Medium (6mm-15mm) 1 03/29/2012 07/15/10 624.00 No
271 1000 ppm Mass Torso/Dorsal, Medium (6mm-15mm) 1 04/18/2012 07/15/10 644.00 Yes
271 1000 ppm Thin 04/18/2012 07/15/10 644.00 Yes
275 1000 ppm Ruffled Fur 06/21/2012 07/15/10 708.00 No
276 1000 ppm Paralysis 06/21/2012 07/15/10 708.00 No
276 1000 ppm Paralysis 07/10/2012 07/15/10 727.00 Yes
277 1000 ppm Lethargic 12/26/2011 07/15/10 530.00 Yes
277 1000 ppm Ulcer/Abscess Torso/Ventral 1 12/26/2011 07/15/10 530.00 Yes
278 1000 ppm Ruffled Fur 06/21/2012 07/15/10 708.00 No
306 3000 ppm Lethargic 07/10/2012 07/15/10 727.00 Yes
306 3000 ppm Ruffled Fur 07/10/2012 07/15/10 727.00 Yes
314 3000 ppm Thin 06/18/2012 07/15/10 705.00 Yes
314 3000 ppm Lethargic 06/18/2012 07/15/10 705.00 Yes
316 3000 ppm Mass Torso/Lateral, Medium (6mm-15mm) 1 06/21/2012 07/15/10 708.00 No
317 3000 ppm Mass Torso/Dorsal, Small (1mm-5mm) 1 05/24/2012 07/15/10 680.00 No
317 3000 ppm Ruffled Fur 06/21/2012 07/15/10 708.00 No
317 3000 ppm Mass Torso/Dorsal, Large (16mm And Larger) 1 06/21/2012 07/15/10 708.00 No
317 3000 ppm Mass Torso/Lateral, Large (16mm And Larger) 1 06/25/2012 07/15/10 712.00 Yes
317 3000 ppm Ruffled Fur 06/25/2012 07/15/10 712.00 Yes
344 3000 ppm Abnormal Breathing 06/18/2012 07/15/10 705.00 Yes
344 3000 ppm Lethargic 06/18/2012 07/15/10 705.00 Yes
344 3000 ppm Head Tilt 06/18/2012 07/15/10 705.00 Yes
346 3000 ppm Eye Abnormality 07/11/2012 07/15/10 728.00 Yes
352 10000 ppm Ruffled Fur 06/21/2012 07/15/10 708.00 No
373 10000 ppm Ruffled Fur 06/21/2012 07/15/10 708.00 No
374 10000 ppm Mass Torso/Lateral, Small (1mm-5mm) 1 03/29/2012 07/15/10 624.00 No
374 10000 ppm Thin 03/29/2012 07/15/10 624.00 No
374 10000 ppm Ruffled Fur 03/29/2012 07/15/10 624.00 No
374 10000 ppm Mass Torso/Dorsal, Small (1mm-5mm) 1 04/26/2012 07/15/10 652.00 No
374 10000 ppm Mass Torso/Lateral, Large (16mm And Larger) 1 05/14/2012 07/15/10 670.00 Yes
381 10000 ppm Thin 03/01/2012 07/15/10 596.00 No
381 10000 ppm Thin 03/29/2012 07/15/10 624.00 No
381 10000 ppm Thin 04/26/2012 07/15/10 652.00 No
381 10000 ppm Thin 05/07/2012 07/15/10 663.00 Yes
383 10000 ppm Ruffled Fur 06/21/2012 07/15/10 708.00 No
384 10000 ppm Ruffled Fur 06/21/2012 07/15/10 708.00 No
386 10000 ppm Ruffled Fur 06/21/2012 07/15/10 708.00 No