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Short-Term Individual Animal Non Neoplastic Diagnosis
Study Information:
Chemical Name: | Acetoin |
CASRN: | ="513-86-0" |
Study Number: | C20724 |
Exposure Route: | RESPIRATORY EXPOSURE WHOLE BODY |
TDMS Number: | 2072403 |
Sex: | Female |
Strain and Species: | Wistar Han Rats |
Female Individual Animal Non Neoplastic Diagnoses
System |
Organ |
Site |
Treatment Group |
Number Examined |
Cage Number |
Animal Number |
Days on Study |
Lesion Found |
Lesion Name |
Lesion Qualifier |
Removal Reason |
Alimentary System |
Liver |
|
100 ppm |
1 |
11 |
503 |
93 |
1 |
Hepatodiaphragmatic Nodule |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
50 ppm |
1 |
7 |
304 |
93 |
1 |
Necrosis |
Moderate |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Iliac |
100 ppm |
1 |
11 |
501 |
93 |
1 |
Infiltration Cellular |
Moderate, Mixed Cell |
Terminal Sacrifice |
Integumentary System |
Skin |
|
Vehicle Control |
10 |
3 |
105 |
93 |
1 |
Ulcer |
Mild |
Terminal Sacrifice |
Respiratory System |
Larynx |
|
800 ppm |
10 |
24 |
1109 |
93 |
1 |
Inflammation |
Minimal, Acute |
Terminal Sacrifice |
Respiratory System |
Lung |
|
800 ppm |
10 |
23 |
1101 |
93 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Urinary System |
Kidney |
Medulla |
Vehicle Control |
10 |
3 |
105 |
93 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Urinary System |
Kidney |
Medulla |
Vehicle Control |
10 |
4 |
109 |
93 |
1 |
Inflammation |
Moderate, Chronic Active |
Terminal Sacrifice |
Urinary System |
Kidney |
Medulla |
800 ppm |
10 |
23 |
1101 |
93 |
1 |
Inflammation |
Moderate, Chronic Active |
Terminal Sacrifice |
Urinary System |
Kidney |
Pelvis |
800 ppm |
10 |
23 |
1101 |
93 |
1 |
Dilatation |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
Pelvis |
800 ppm |
10 |
23 |
1101 |
93 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Urinary System |
Kidney |
Transit Epithe |
800 ppm |
10 |
23 |
1101 |
93 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
10 |
3 |
103 |
93 |
1 |
Nephropathy |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
10 |
3 |
104 |
93 |
1 |
Nephropathy |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
10 |
4 |
110 |
93 |
1 |
Nephropathy |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
|
800 ppm |
10 |
24 |
1106 |
93 |
1 |
Nephropathy |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
|
800 ppm |
10 |
24 |
1110 |
93 |
1 |
Nephropathy |
Minimal |
Terminal Sacrifice |
Urinary System |
Urinary Bladder |
Transit Epithe |
100 ppm |
1 |
11 |
501 |
93 |
1 |
Hyperplasia |
Marked |
Terminal Sacrifice |
Urinary System |
Urinary Bladder |
|
100 ppm |
1 |
11 |
501 |
93 |
1 |
Calculus Gross Observation |
|
Terminal Sacrifice |