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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: Acetoin
CASRN: ="513-86-0"
Study Number: C20724
Exposure Route: RESPIRATORY EXPOSURE WHOLE BODY
TDMS Number: 2072403
Sex: Female
Strain and Species: Wistar Han Rats

Female Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver 100 ppm 1 11 503 93 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 50 ppm 1 7 304 93 1 Necrosis Moderate Terminal Sacrifice
Hematopoietic System Lymph Node Iliac 100 ppm 1 11 501 93 1 Infiltration Cellular Moderate, Mixed Cell Terminal Sacrifice
Integumentary System Skin Vehicle Control 10 3 105 93 1 Ulcer Mild Terminal Sacrifice
Respiratory System Larynx 800 ppm 10 24 1109 93 1 Inflammation Minimal, Acute Terminal Sacrifice
Respiratory System Lung 800 ppm 10 23 1101 93 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Urinary System Kidney Medulla Vehicle Control 10 3 105 93 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Urinary System Kidney Medulla Vehicle Control 10 4 109 93 1 Inflammation Moderate, Chronic Active Terminal Sacrifice
Urinary System Kidney Medulla 800 ppm 10 23 1101 93 1 Inflammation Moderate, Chronic Active Terminal Sacrifice
Urinary System Kidney Pelvis 800 ppm 10 23 1101 93 1 Dilatation Mild Terminal Sacrifice
Urinary System Kidney Pelvis 800 ppm 10 23 1101 93 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Urinary System Kidney Transit Epithe 800 ppm 10 23 1101 93 1 Hyperplasia Moderate Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 3 103 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 3 104 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 4 110 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 800 ppm 10 24 1106 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 800 ppm 10 24 1110 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Urinary Bladder Transit Epithe 100 ppm 1 11 501 93 1 Hyperplasia Marked Terminal Sacrifice
Urinary System Urinary Bladder 100 ppm 1 11 501 93 1 Calculus Gross Observation Terminal Sacrifice