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Current Search Critera

Short-Term Study Individual Animal Clinical Observations

Study Information:

Chemical Name: 2,3-Pentanedione
CASRN: ="600-14-6"
Study Number: C08010
Exposure Route: RESPIRATORY EXPOSURE WHOLE BODY
TDMS Number: 0801001
Sex: Female
Strain and Species: Wistar Han Rats

Animal Number Dose Group Clinical Observation Qualifier Incident Number Observation Date First Dose Date Days On Study Removal Observation
901 50 ppm Sneezing 12/10/2010 9/14/10 88.00 No
901 50 ppm Sneezing 12/15/2010 9/14/10 93.00 Yes
902 50 ppm Sneezing 10/22/2010 9/14/10 39.00 No
902 50 ppm Sneezing 11/26/2010 9/14/10 74.00 No
904 50 ppm Sneezing 10/15/2010 9/14/10 32.00 No
905 50 ppm Sneezing 10/22/2010 9/14/10 39.00 No
906 50 ppm Sneezing 11/12/2010 9/14/10 60.00 No
906 50 ppm Eye Abnormality 11/12/2010 9/14/10 60.00 No
906 50 ppm Eye Abnormality 11/19/2010 9/14/10 67.00 No
906 50 ppm Eye Abnormality 11/26/2010 9/14/10 74.00 No
906 50 ppm Sneezing 11/26/2010 9/14/10 74.00 No
906 50 ppm Sneezing 12/03/2010 9/14/10 81.00 No
906 50 ppm Eye Abnormality 12/03/2010 9/14/10 81.00 No
906 50 ppm Sneezing 12/10/2010 9/14/10 88.00 No
906 50 ppm Eye Abnormality 12/10/2010 9/14/10 88.00 No
907 50 ppm Eye Abnormality 11/12/2010 9/14/10 60.00 No
907 50 ppm Sneezing 11/12/2010 9/14/10 60.00 No
907 50 ppm Eye Abnormality 11/19/2010 9/14/10 67.00 No
907 50 ppm Eye Abnormality 11/26/2010 9/14/10 74.00 No
907 50 ppm Abnormal Breathing 12/03/2010 9/14/10 81.00 No
907 50 ppm Eye Abnormality 12/03/2010 9/14/10 81.00 No
907 50 ppm Abnormal Breathing 12/10/2010 9/14/10 88.00 No
907 50 ppm Eye Abnormality 12/10/2010 9/14/10 88.00 No
907 50 ppm Abnormal Breathing 12/15/2010 9/14/10 93.00 Yes
907 50 ppm Eye Abnormality 12/15/2010 9/14/10 93.00 Yes
908 50 ppm Eye Abnormality 11/12/2010 9/14/10 60.00 No
908 50 ppm Abnormal Breathing 11/19/2010 9/14/10 67.00 No
908 50 ppm Eye Abnormality 11/19/2010 9/14/10 67.00 No
908 50 ppm Eye Abnormality 11/26/2010 9/14/10 74.00 No
908 50 ppm Eye Abnormality 12/03/2010 9/14/10 81.00 No
908 50 ppm Eye Abnormality 12/10/2010 9/14/10 88.00 No
908 50 ppm Eye Abnormality 12/15/2010 9/14/10 93.00 Yes
909 50 ppm Sneezing 10/29/2010 9/14/10 46.00 No
909 50 ppm Eye Abnormality 11/26/2010 9/14/10 74.00 No
909 50 ppm Eye Abnormality 12/03/2010 9/14/10 81.00 No
909 50 ppm Eye Abnormality 12/10/2010 9/14/10 88.00 No
909 50 ppm Sneezing 12/10/2010 9/14/10 88.00 No
909 50 ppm Sneezing 12/15/2010 9/14/10 93.00 Yes
909 50 ppm Eye Abnormality 12/15/2010 9/14/10 93.00 Yes
910 50 ppm Eye Abnormality 11/12/2010 9/14/10 60.00 No
910 50 ppm Eye Abnormality 11/19/2010 9/14/10 67.00 No
910 50 ppm Eye Abnormality 11/26/2010 9/14/10 74.00 No
910 50 ppm Eye Abnormality 12/10/2010 9/14/10 88.00 No
910 50 ppm Eye Abnormality 12/15/2010 9/14/10 93.00 Yes
1101 100 ppm Sneezing 11/12/2010 9/14/10 60.00 No
1101 100 ppm Eye Abnormality 11/26/2010 9/14/10 74.00 No
1101 100 ppm Eye Abnormality 12/03/2010 9/14/10 81.00 No
1101 100 ppm Eye Abnormality 12/10/2010 9/14/10 88.00 No
1101 100 ppm Sneezing 12/10/2010 9/14/10 88.00 No
1101 100 ppm Abnormal Breathing 12/10/2010 9/14/10 88.00 No
1101 100 ppm Eye Abnormality 12/15/2010 9/14/10 93.00 Yes
1101 100 ppm Sneezing 12/15/2010 9/14/10 93.00 Yes
1101 100 ppm Abnormal Breathing 12/15/2010 9/14/10 93.00 Yes
1102 100 ppm Sneezing 10/15/2010 9/14/10 32.00 No
1102 100 ppm Sneezing 10/22/2010 9/14/10 39.00 No
1102 100 ppm Sneezing 10/29/2010 9/14/10 46.00 No
1102 100 ppm Sneezing 11/05/2010 9/14/10 53.00 No
1102 100 ppm Sneezing 11/12/2010 9/14/10 60.00 No
1102 100 ppm Sneezing 11/26/2010 9/14/10 74.00 No
1102 100 ppm Sneezing 12/03/2010 9/14/10 81.00 No
1102 100 ppm Eye Abnormality 12/10/2010 9/14/10 88.00 No
1102 100 ppm Sneezing 12/10/2010 9/14/10 88.00 No
1102 100 ppm Eye Abnormality 12/15/2010 9/14/10 93.00 Yes
1102 100 ppm Sneezing 12/15/2010 9/14/10 93.00 Yes
1103 100 ppm Sneezing 10/08/2010 9/14/10 25.00 No
1103 100 ppm Sneezing 10/29/2010 9/14/10 46.00 No
1103 100 ppm Sneezing 11/05/2010 9/14/10 53.00 No
1103 100 ppm Sneezing 11/19/2010 9/14/10 67.00 No
1103 100 ppm Sneezing 12/03/2010 9/14/10 81.00 No
1104 100 ppm Sneezing 10/08/2010 9/14/10 25.00 No
1104 100 ppm Sneezing 11/05/2010 9/14/10 53.00 No
1104 100 ppm Sneezing 11/12/2010 9/14/10 60.00 No
1104 100 ppm Sneezing 11/19/2010 9/14/10 67.00 No
1104 100 ppm Eye Abnormality 11/19/2010 9/14/10 67.00 No
1104 100 ppm Eye Abnormality 11/26/2010 9/14/10 74.00 No
1104 100 ppm Sneezing 11/26/2010 9/14/10 74.00 No
1104 100 ppm Sneezing 12/03/2010 9/14/10 81.00 No
1104 100 ppm Eye Abnormality 12/10/2010 9/14/10 88.00 No
1104 100 ppm Sneezing 12/10/2010 9/14/10 88.00 No
1104 100 ppm Eye Abnormality 12/15/2010 9/14/10 93.00 Yes
1104 100 ppm Sneezing 12/15/2010 9/14/10 93.00 Yes
1105 100 ppm Eye Abnormality 11/12/2010 9/14/10 60.00 No
1105 100 ppm Sneezing 11/19/2010 9/14/10 67.00 No
1105 100 ppm Eye Abnormality 11/19/2010 9/14/10 67.00 No
1105 100 ppm Eye Abnormality 11/26/2010 9/14/10 74.00 No
1105 100 ppm Eye Abnormality 12/03/2010 9/14/10 81.00 No
1105 100 ppm Eye Abnormality 12/10/2010 9/14/10 88.00 No
1105 100 ppm Eye Abnormality 12/15/2010 9/14/10 93.00 Yes
1106 100 ppm Eye Abnormality 11/12/2010 9/14/10 60.00 No
1106 100 ppm Sneezing 11/12/2010 9/14/10 60.00 No
1106 100 ppm Eye Abnormality 11/19/2010 9/14/10 67.00 No
1106 100 ppm Abnormal Breathing 11/19/2010 9/14/10 67.00 No
1106 100 ppm Eye Abnormality 11/26/2010 9/14/10 74.00 No
1106 100 ppm Abnormal Breathing 11/26/2010 9/14/10 74.00 No
1106 100 ppm Abnormal Breathing 12/03/2010 9/14/10 81.00 No
1106 100 ppm Eye Abnormality 12/03/2010 9/14/10 81.00 No
1106 100 ppm Sneezing 12/03/2010 9/14/10 81.00 No
1106 100 ppm Eye Abnormality 12/10/2010 9/14/10 88.00 No
1106 100 ppm Abnormal Breathing 12/10/2010 9/14/10 88.00 No
1106 100 ppm Eye Abnormality 12/15/2010 9/14/10 93.00 Yes
1106 100 ppm Abnormal Breathing 12/15/2010 9/14/10 93.00 Yes
1107 100 ppm Sneezing 10/08/2010 9/14/10 25.00 No
1107 100 ppm Sneezing 10/15/2010 9/14/10 32.00 No
1107 100 ppm Sneezing 10/22/2010 9/14/10 39.00 No
1107 100 ppm Sneezing 10/29/2010 9/14/10 46.00 No
1107 100 ppm Eye Abnormality 11/12/2010 9/14/10 60.00 No
1107 100 ppm Sneezing 11/12/2010 9/14/10 60.00 No
1107 100 ppm Eye Abnormality 11/19/2010 9/14/10 67.00 No
1107 100 ppm Sneezing 11/26/2010 9/14/10 74.00 No
1107 100 ppm Sneezing 12/03/2010 9/14/10 81.00 No
1108 100 ppm Eye Abnormality 10/29/2010 9/14/10 46.00 No
1108 100 ppm Eye Abnormality 11/05/2010 9/14/10 53.00 No
1108 100 ppm Sneezing 11/05/2010 9/14/10 53.00 No
1108 100 ppm Eye Abnormality 11/12/2010 9/14/10 60.00 No
1108 100 ppm Sneezing 11/19/2010 9/14/10 67.00 No
1108 100 ppm Eye Abnormality 11/19/2010 9/14/10 67.00 No
1108 100 ppm Sneezing 11/26/2010 9/14/10 74.00 No
1108 100 ppm Eye Abnormality 11/26/2010 9/14/10 74.00 No
1108 100 ppm Eye Abnormality 12/03/2010 9/14/10 81.00 No
1108 100 ppm Eye Abnormality 12/10/2010 9/14/10 88.00 No
1108 100 ppm Eye Abnormality 12/15/2010 9/14/10 93.00 Yes
1109 100 ppm Abnormal Breathing 10/29/2010 9/14/10 46.00 No
1109 100 ppm Sneezing 10/29/2010 9/14/10 46.00 No
1109 100 ppm Abnormal Breathing 11/05/2010 9/14/10 53.00 No
1109 100 ppm Eye Abnormality 11/12/2010 9/14/10 60.00 No
1109 100 ppm Eye Abnormality 11/19/2010 9/14/10 67.00 No
1109 100 ppm Eye Abnormality 11/26/2010 9/14/10 74.00 No
1109 100 ppm Eye Abnormality 12/03/2010 9/14/10 81.00 No
1109 100 ppm Eye Abnormality 12/10/2010 9/14/10 88.00 No
1109 100 ppm Sneezing 12/10/2010 9/14/10 88.00 No
1109 100 ppm Eye Abnormality 12/15/2010 9/14/10 93.00 Yes
1109 100 ppm Sneezing 12/15/2010 9/14/10 93.00 Yes
1110 100 ppm Eye Abnormality 11/05/2010 9/14/10 53.00 No
1110 100 ppm Eye Abnormality 11/12/2010 9/14/10 60.00 No
1110 100 ppm Eye Abnormality 11/19/2010 9/14/10 67.00 No
1110 100 ppm Sneezing 11/19/2010 9/14/10 67.00 No
1110 100 ppm Eye Abnormality 11/26/2010 9/14/10 74.00 No
1110 100 ppm Eye Abnormality 12/03/2010 9/14/10 81.00 No
1110 100 ppm Eye Abnormality 12/10/2010 9/14/10 88.00 No
1110 100 ppm Eye Abnormality 12/15/2010 9/14/10 93.00 Yes