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Short-Term Study Body Weights

Study Information:

Chemical Name: 2,3-Pentanedione
CASRN: ="600-14-6"
Study Number: C08010
Exposure Route: RESPIRATORY EXPOSURE WHOLE BODY
TDMS Number: 0801001
Sex: Male
Strain and Species: Wistar Han Rats

Animal Number Cage Number Dose Group Days On Study Week 1 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 14 Removal Reason
1 1 Vehicle Control 93 163.5 229.9 257.2 283.1 302.5 320 328.5 343.3 344 356 359.1 372 367.9 Terminal Sacrifice
2 1 Vehicle Control 93 182.9 261.1 290.2 316.8 337.8 362.5 373.8 382.1 390.5 400.4 410.5 415.3 421.3 Terminal Sacrifice
3 1 Vehicle Control 93 172.5 224.1 246.3 269.9 286.9 301.1 315.1 326.1 333.2 338.4 343.6 347.8 349.1 Terminal Sacrifice
4 1 Vehicle Control 93 196.4 258.9 284.7 306.8 322.8 340.9 358.5 365.1 372.7 378.2 386.9 394.2 398.6 Terminal Sacrifice
5 1 Vehicle Control 93 170.5 232 263.7 287 306.4 328 342.4 349.8 353.9 361.1 367.2 374.8 378.8 Terminal Sacrifice
6 2 Vehicle Control 93 191.7 241.9 266.2 293 313.6 327.3 339.5 354.7 361.8 370.8 377.1 385.7 388.8 Terminal Sacrifice
7 2 Vehicle Control 93 191.8 244.2 274.5 298 319.6 334.6 349.5 364.2 369.2 379.7 385.5 391.7 394.9 Terminal Sacrifice
8 2 Vehicle Control 93 180.9 237.3 260.8 282.1 299.3 314.3 325.1 334.5 336.9 345.6 348.8 355.2 356 Terminal Sacrifice
9 2 Vehicle Control 93 176.1 231.8 261.3 282.5 298.1 316.3 328.3 334.5 344.4 358.4 359.3 372.7 375 Terminal Sacrifice
10 2 Vehicle Control 93 185.7 249.5 280.3 308.2 328.1 346.2 358 370 377 385.4 397.5 405.1 407.8 Terminal Sacrifice
201 5 6.25ppm 93 159.2 219.1 244.9 266.4 281.4 298.6 313.3 325.5 340.6 350.3 356.9 365.8 367.7 Terminal Sacrifice
202 5 6.25ppm 93 167 225.9 251.7 275.3 295 312.8 329.6 340.4 348.8 358.8 365.4 375.2 375.7 Terminal Sacrifice
203 5 6.25ppm 93 176.2 230.7 247.3 261.8 274.2 295.2 302.1 311.4 316.8 320 327.7 335.7 338.4 Terminal Sacrifice
204 5 6.25ppm 93 186.1 248.6 278.1 309.8 329.4 351.9 364.4 374.2 380.1 386.5 397.9 410.4 413 Terminal Sacrifice
205 5 6.25ppm 93 184.9 243.9 268.1 289.4 295.9 318 326.9 333.3 337 345.2 353.8 362.4 366.6 Terminal Sacrifice
206 6 6.25ppm 93 174.9 237.9 266 288.8 306 334.5 348.4 354.8 363.9 370.6 373.7 384.2 385.2 Terminal Sacrifice
207 6 6.25ppm 93 195.4 249.5 271.5 297.1 311 332.3 343.7 356.2 359.3 368.1 375 377.5 380.8 Terminal Sacrifice
208 6 6.25ppm 93 196.5 256.8 279.2 297.6 309.7 336.8 348 355.9 368.3 380.6 389 395.2 395.3 Terminal Sacrifice
209 6 6.25ppm 93 179.6 237.9 262.8 285.8 307.2 321.3 331.7 341.5 350.6 355.2 363 372.2 375.5 Terminal Sacrifice
210 6 6.25ppm 93 190.3 256.2 290 321.5 341.9 366.9 382.6 393.2 403.9 417.1 426.2 430.6 434.2 Terminal Sacrifice
401 9 12.5ppm 93 182 240.6 262.9 281.8 307.7 326.7 337 351.2 360.3 370.7 373.1 385.1 376.6 Terminal Sacrifice
402 9 12.5ppm 93 174.7 238.9 270.3 296.5 309.5 333.6 352 364.5 370.6 383 394 403.9 405.2 Terminal Sacrifice
403 9 12.5ppm 93 180.9 238.6 271.5 298.1 318.1 333.2 339.8 347.9 348.4 356.1 364.1 369.6 371.6 Terminal Sacrifice
404 9 12.5ppm 93 205.3 263.3 294.4 318.7 337.3 349.7 359.1 374.9 377.9 384.8 397.8 405.7 408.9 Terminal Sacrifice
405 9 12.5ppm 93 169.4 222.4 247.3 268 288.6 304.5 314.5 327.2 338.5 345.3 355.1 355.7 361.1 Terminal Sacrifice
406 10 12.5ppm 93 172.7 223.8 251.2 274.5 294.8 312.1 330.1 341.2 348.8 357.3 364.8 372.9 375 Terminal Sacrifice
407 10 12.5ppm 93 179.6 241.3 271.7 296.3 317 328.7 342.7 353.2 358.7 371.7 378.7 391.7 393.2 Terminal Sacrifice
408 10 12.5ppm 93 178.9 246.7 276.8 300.6 320.8 336.6 350.6 357.1 368.1 376.1 389.3 394.8 401.2 Terminal Sacrifice
409 10 12.5ppm 93 193.5 248.2 275.5 297.9 313.7 326.1 341 345.6 350.9 359.9 366.9 375.3 377.5 Terminal Sacrifice
410 10 12.5ppm 93 167.4 231.1 265.6 293.6 316.4 333.3 348.5 354.9 363.4 371.9 380.1 385.5 394.3 Terminal Sacrifice
601 13 25ppm 93 186.3 258.2 289.4 315 331.5 346.7 359.5 372 379.6 392.4 399.4 402.6 405.6 Terminal Sacrifice
602 13 25ppm 93 188.4 251.5 278.5 304.1 321.9 334.4 349.6 358.6 374.7 381.6 388 395.8 405.5 Terminal Sacrifice
603 13 25ppm 93 164.5 222.6 254.5 281.6 302.1 319.7 334.4 346.6 358.6 370.2 381.4 389.8 393.5 Terminal Sacrifice
604 13 25ppm 93 174.9 243.3 277.6 304.2 317.1 336.3 351.2 365.4 378.1 389.2 398.2 409 409.6 Terminal Sacrifice
605 13 25ppm 93 163.3 215.2 238.4 254.2 268.5 275.4 289.6 298.8 304.2 311.7 315.1 320.7 319.9 Terminal Sacrifice
606 14 25ppm 93 196.4 268.9 301.6 337.2 359.2 377.4 388.9 402.3 411.1 422.2 436.2 443.1 449 Terminal Sacrifice
607 14 25ppm 93 183.5 248.6 274.5 297.3 303.2 316.9 327.5 345.2 357.1 364.9 376 380.2 381.2 Terminal Sacrifice
608 14 25ppm 93 177.5 251.1 282.3 315.9 337.1 362 378.5 392 404.5 413.9 418.4 427.9 436.2 Terminal Sacrifice
609 14 25ppm 93 188.5 249.6 275.5 297.9 320.5 338.2 347.1 354.4 362.6 373.3 381.4 390.5 392.7 Terminal Sacrifice
610 14 25ppm 93 173.6 227.3 252.6 274.3 293 310.1 321.3 332.5 339.6 346.7 357.4 367.8 367.5 Terminal Sacrifice
801 17 50ppm 93 168.3 218.6 240.8 257.5 273.6 285.8 298 305.8 314.6 319.6 322.1 331.3 333 Terminal Sacrifice
802 17 50ppm 93 191.7 259.3 281.6 306 330.8 350.5 371.3 381.7 395.2 397.1 408.1 419.2 419.3 Terminal Sacrifice
803 17 50ppm 93 189.3 254.9 256.4 292.3 328.6 342.9 367.7 382.4 395.4 409.6 423.6 436 441.9 Terminal Sacrifice
804 17 50ppm 93 191.9 250.5 282 310.5 331.5 350.4 359 368.1 374.1 383.2 396.8 407.8 412.5 Terminal Sacrifice
805 17 50ppm 93 193.1 253.4 278.1 297.1 319.6 336.9 354.2 358 366.7 374.4 387.8 391.9 392.5 Terminal Sacrifice
806 18 50ppm 93 162.2 200.6 219.8 232 241.7 251.1 261.1 262.3 268.5 278.5 281.7 286.6 292.1 Terminal Sacrifice
807 18 50ppm 93 171.1 220.1 243.8 269.6 283 293.6 302.3 313.3 315.2 323.8 333.6 339.7 342.1 Terminal Sacrifice
808 18 50ppm 93 174.5 230.1 262.6 288.7 309.4 324.9 336.7 344.7 357.9 364.5 376.5 386.1 391.2 Terminal Sacrifice
809 18 50ppm 93 191.1 257.7 281 307.5 327.7 345.3 356.5 367.6 377.7 387.4 402.1 412.7 415.5 Terminal Sacrifice
810 18 50ppm 93 161.8 213.4 236.1 251.1 270.7 286.4 299.6 304.6 311.3 325.7 332.2 346.2 345.4 Terminal Sacrifice
1001 21 100ppm 93 167.2 217.5 247.1 271.7 292.4 307.6 317.1 328 334.8 337.7 344.8 351.8 356.5 Terminal Sacrifice
1002 21 100ppm 93 181.4 233 256 276.4 293.5 308.6 319.6 326.9 332.7 342.8 358.3 361.4 364.4 Terminal Sacrifice
1003 21 100ppm 93 161 205.6 235 260.3 277.3 301.7 312.7 321.6 334.5 346.6 353.8 361.5 368.2 Terminal Sacrifice
1004 21 100ppm 93 177.4 221.3 245.8 269.1 278.8 301.8 316 323.3 328.6 342.5 355 362 364.4 Terminal Sacrifice
1005 21 100ppm 93 172.2 233.2 259.6 291 305.7 334.9 344.8 350.8 355.3 370.5 381.3 386.3 387.9 Terminal Sacrifice
1006 22 100ppm 93 175.4 237 258.6 286.2 307.8 328.1 341.2 346.9 350.8 364.7 382.8 383.5 382.1 Terminal Sacrifice
1007 22 100ppm 93 192.8 248.1 280.2 312.8 332 344.7 341.8 352.5 364.3 375.8 365.7 381.4 390 Terminal Sacrifice
1008 22 100ppm 93 167.2 209.3 237.6 253 268.3 286.2 296.9 301.6 305.3 314.8 321 323.6 324.3 Terminal Sacrifice
1009 22 100ppm 93 162.3 216.7 248.3 277.3 292.3 313.7 325.6 330 343.6 352.6 370.6 376.2 380 Terminal Sacrifice
1010 22 100ppm 93 161.6 205.7 238.1 262.8 271.9 276.4 291.1 299.1 300.8 299.1 301.4 319.7 319.1 Terminal Sacrifice
* All body weights in grams