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Short-Term Study Body Weights

Study Information:

Chemical Name: 2,3-Pentanedione
CASRN: ="600-14-6"
Study Number: C08010
Exposure Route: RESPIRATORY EXPOSURE WHOLE BODY
TDMS Number: 0801002
Sex: Male
Strain and Species: B6C3F1 Mice

Animal Number Cage Number Dose Group Days On Study Week 1 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 14 Removal Reason
1 1 Vehicle Control 95 24.2 25.9 26.5 27.9 28.4 29.3 30.6 31 32.2 33.7 34.7 35.5 35.6 Terminal Sacrifice
2 1 Vehicle Control 95 23.2 24.7 26.3 26 27.1 27.9 28.4 29.2 29.7 30.9 31.8 32.8 34 Terminal Sacrifice
3 1 Vehicle Control 95 24.5 26.9 27.8 28.2 29.2 29.8 30.9 31.2 31.1 32.2 32.8 32.9 33.9 Terminal Sacrifice
4 1 Vehicle Control 95 24.4 26.3 27.2 27.9 28.5 29.3 30.1 30.4 31.7 31.8 32.2 32.8 33 Terminal Sacrifice
5 1 Vehicle Control 95 23.2 25.1 25.7 26.3 26.9 27.7 28.7 29.2 30.9 31.5 32.7 33 33.9 Terminal Sacrifice
6 2 Vehicle Control 95 24.9 25.6 26.2 26.9 27.8 28.5 29 29.4 29.9 31 32 32.6 32.8 Terminal Sacrifice
7 2 Vehicle Control 95 24.5 25.7 26 26.8 27.1 27.4 28.7 28.5 29.2 30.2 31.2 31.8 32.2 Terminal Sacrifice
8 2 Vehicle Control 95 24.4 24.9 25.4 26.1 27.1 27 28.2 28.9 29.4 30.1 31.2 31.5 32.7 Terminal Sacrifice
9 2 Vehicle Control 95 25.1 26.2 26.7 27.3 28.5 29 30.6 31.7 32.4 33.6 35 35.8 35.9 Terminal Sacrifice
10 2 Vehicle Control 95 24.9 26 26.8 27.2 27.9 28.2 29 29.5 30.1 31 31.7 32.6 32.8 Terminal Sacrifice
201 5 6.25ppm 95 22.4 23.8 25 25.5 26.1 26.9 27.8 28.7 29.3 29.9 31.1 31.7 32.8 Terminal Sacrifice
202 5 6.25ppm 95 23.2 24.6 25.3 26 26.4 27.5 28 28.8 29.1 30.5 30.9 31.7 32.1 Terminal Sacrifice
203 5 6.25ppm 95 24.6 25.3 26.3 27.5 28 28.3 28.8 29.6 30.4 31 31.8 33 34 Terminal Sacrifice
204 5 6.25ppm 95 24.6 26.1 27.1 27.9 28.3 29.4 29.6 30.2 31.3 32.3 33.7 34.5 34.8 Terminal Sacrifice
205 5 6.25ppm 95 23.3 24.6 25.4 25.5 26.5 27.1 27.7 28.4 28.6 29.6 30.1 31.1 31.2 Terminal Sacrifice
206 6 6.25ppm 95 23.8 26.7 27.4 28.4 29.3 29.7 31.4 32.3 33.3 34.2 35.9 36.3 37.1 Terminal Sacrifice
207 6 6.25ppm 95 25.3 26.9 27.5 28.1 28.7 28.8 30.1 31.3 31.6 32.8 33.4 34.5 35.1 Terminal Sacrifice
208 6 6.25ppm 95 25.7 27.1 28 28.8 29.8 31.1 32.2 33.2 34 35.2 36.3 37.1 37.9 Terminal Sacrifice
209 6 6.25ppm 95 24 25.5 26.1 26.6 26.8 27.4 28.5 29.6 29.7 30.4 31.5 32.1 33.1 Terminal Sacrifice
210 6 6.25ppm 95 22.7 24.3 24.8 25.6 26.5 27 27.4 27.6 28 28.7 29.6 30.3 30.9 Terminal Sacrifice
401 9 12.5ppm 95 22.3 24.4 25.1 26 26.8 27.4 27.9 29.4 30.5 31.2 32.3 33.2 33.5 Terminal Sacrifice
402 9 12.5ppm 95 24.3 26.3 27.1 28 29 29.5 30.9 31.7 32.8 33.8 34.4 35.4 36.3 Terminal Sacrifice
403 9 12.5ppm 95 22.7 24.4 24.8 25.7 26.7 26.8 27.8 28.2 28.6 29 29.9 30.8 31.1 Terminal Sacrifice
404 9 12.5ppm 95 23.4 24.6 25.2 26.1 26.9 27.7 28.8 29.5 30.4 31.1 32.2 32.5 32.9 Terminal Sacrifice
405 9 12.5ppm 95 25.9 26.7 27.1 28 29.1 29.5 30.5 31.1 31.7 32.5 33.6 34.7 35.4 Terminal Sacrifice
406 10 12.5ppm 95 24 25.7 26.1 26.8 28.1 28.9 30.2 31.4 32.8 33.8 34.5 35.7 36.2 Terminal Sacrifice
407 10 12.5ppm 95 25.8 27.6 28.6 29.6 30.6 31.2 31.9 33.3 33.7 34.3 34.9 35.3 36 Terminal Sacrifice
408 10 12.5ppm 95 24.6 26.7 27.5 28.4 29.1 29.6 30.1 30.9 31.3 32.1 32.9 33.8 34.3 Terminal Sacrifice
409 10 12.5ppm 95 24.9 25.7 25.7 26.8 27.9 28.7 29.8 30.7 31.4 32.4 33.5 34.6 35.2 Terminal Sacrifice
410 10 12.5ppm 95 23.3 23.8 24.7 25.6 27.2 28.3 28.9 29.6 30.4 31.5 32 32.5 33 Terminal Sacrifice
601 13 25ppm 95 23.3 24.8 25.4 25.7 26.6 26.8 27.6 28.3 27.7 28.5 29.3 29.6 29.4 Terminal Sacrifice
602 13 25ppm 95 23.4 25.5 26.6 28.3 29.1 30 30.8 31.5 32.8 33.8 34.8 36.1 36.8 Terminal Sacrifice
603 13 25ppm 95 24.5 24.9 25.4 26.8 27.8 28.7 29.5 30.5 31 31.8 33 33.8 34.2 Terminal Sacrifice
604 13 25ppm 95 23.6 26.1 26.9 28 29.2 30.3 30.6 32 32.6 33.7 34.6 35.5 36.4 Terminal Sacrifice
605 13 25ppm 95 23.6 23.7 24.2 25.5 26.6 27.1 28 28.3 28.7 30.4 31 32.7 33.2 Terminal Sacrifice
606 14 25ppm 95 24.8 25.2 25.9 27 28.2 28.6 29.7 31 31.3 32.2 33 34 34.1 Terminal Sacrifice
607 14 25ppm 95 24.3 26.5 27.3 28.5 29 29.6 30.5 31.1 31.8 32.9 34.2 34.3 35.6 Terminal Sacrifice
608 14 25ppm 95 24.8 26.3 26.8 28 28.7 29.6 30.8 32 32.3 33.6 34.6 35.9 36.3 Terminal Sacrifice
609 14 25ppm 95 23.9 25.1 25.8 26.8 27.4 28.1 28.7 29.3 29.9 30.5 31 31.6 32 Terminal Sacrifice
610 14 25ppm 95 24.4 25.3 26.2 26.8 27.6 29 29.3 30.2 30.6 31.7 32 32.9 32.9 Terminal Sacrifice
801 17 50ppm 95 23 24.7 24.3 25.6 26.1 26.7 27.6 27.7 28.7 29.2 29.4 29.9 29.9 Terminal Sacrifice
802 17 50ppm 95 23.7 23.5 24.7 25 25.7 26.7 27.3 27.8 28.4 28.9 29.6 29.4 29.9 Terminal Sacrifice
803 17 50ppm 95 24.5 25.2 25.3 26.1 26.6 26.8 28.1 27.7 29 28.4 29.5 29.2 29.9 Terminal Sacrifice
804 17 50ppm 95 24.8 24.5 25.5 26.4 27.4 27.5 28.1 28.7 29.2 29.4 30.7 31.5 31 Terminal Sacrifice
805 17 50ppm 95 22.3 23.3 24 24.3 24.6 24.8 25.8 26 25.4 26 26.7 26 26.7 Terminal Sacrifice
806 18 50ppm 95 24.8 23.6 24.4 24.9 25.8 25.9 26.9 26.9 27.2 27.9 28.9 29.1 29.3 Terminal Sacrifice
807 18 50ppm 95 25.2 24.5 24.8 25.5 26.6 26.7 26.7 27.7 28.7 29 29.5 30.2 30.1 Terminal Sacrifice
808 18 50ppm 95 23.5 25.5 26.3 25.9 26.5 27.4 28.2 28.6 29.6 30.1 29.8 29.6 31 Terminal Sacrifice
809 18 50ppm 95 23.6 24 24.5 25.3 26.1 25.9 26.7 27.3 27.4 26.6 26.8 27.9 27.9 Terminal Sacrifice
810 18 50ppm 95 23.6 25.2 25.4 26.2 27.8 28.3 29.1 29 29.4 29.3 29.9 30.1 29.9 Terminal Sacrifice
1001 21 100ppm 95 19.6 21.3 21.8 22.2 22.1 22.7 22.7 22.7 22.7 23.8 24 24.7 24.3 Terminal Sacrifice
1002 21 100ppm 95 20.5 22.4 22.4 23.5 23.5 22.8 21 21.1 21.8 22.3 22.3 22.1 23 Terminal Sacrifice
1003 21 100ppm 95 19.6 21.6 22.4 23.1 23.1 22.3 23.5 23.6 23.6 24.4 25.2 24.8 25.7 Terminal Sacrifice
1004 21 100ppm 95 20.5 22.1 21 21.1 21.3 21.2 21.7 21.4 22.6 22.9 22.9 23.6 22 Terminal Sacrifice
1005 21 100ppm 95 19.1 20.8 21.4 20.9 22.6 22.5 22.3 21.7 23.7 25.2 25.1 24.6 25.1 Terminal Sacrifice
1006 22 100ppm 95 20.3 21.2 22.2 21.9 20.3 21.7 21.6 21.6 21.5 23.1 23.2 23.2 22.1 Terminal Sacrifice
1007 22 100ppm 95 21.1 20.8 21.1 21.9 21.7 23.2 23.5 23.2 24.2 24.6 24.4 22.7 24.1 Terminal Sacrifice
1008 22 100ppm 95 19.8 20.6 21.1 21.5 21.9 21.6 22.3 22.5 23.4 23.7 21.8 24.3 23.5 Terminal Sacrifice
1009 22 100ppm 95 19.2 20.5 20.4 20.4 21.2 21.1 20.5 21.2 20.5 21.6 22 22.1 22.4 Terminal Sacrifice
1010 22 100ppm 95 19.7 22.3 23.5 21.5 20.2 20.9 20.8 21.9 22 22.1 22 20.4 21 Terminal Sacrifice
* All body weights in grams