If this is the first time you are viewing this file, please choose 'Save As' from the 'File' menu and resave this file as an Excel file type. This will greatly speed up future viewings of this file.

Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: Perfluorononanoic Acid
CASRN: ="375-95-1"
Study Number: C04049
Exposure Route: GAVAGE
TDMS Number: 0404901
Sex: Male
Strain and Species: HSD Rats

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Hepatocyte 0.625 mg/kg 10 115 711 29 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 0.625 mg/kg 10 115 712 29 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 0.625 mg/kg 10 115 713 29 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 0.625 mg/kg 10 115 714 29 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 0.625 mg/kg 10 115 715 29 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 0.625 mg/kg 10 116 716 29 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 0.625 mg/kg 10 116 717 29 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 0.625 mg/kg 10 116 718 29 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 0.625 mg/kg 10 116 719 29 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 0.625 mg/kg 10 116 720 29 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 117 721 29 1 Cytoplasmic Alteration Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 117 722 29 1 Cytoplasmic Alteration Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 117 723 29 1 Cytoplasmic Alteration Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 117 724 29 1 Cytoplasmic Alteration Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 117 725 29 1 Cytoplasmic Alteration Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 118 726 29 1 Cytoplasmic Alteration Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 118 727 29 1 Cytoplasmic Alteration Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 118 728 29 1 Cytoplasmic Alteration Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 118 729 29 1 Cytoplasmic Alteration Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 118 730 29 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 119 731 29 1 Cytoplasmic Alteration Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 119 732 29 1 Cytoplasmic Alteration Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 119 733 29 1 Cytoplasmic Alteration Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 119 734 29 1 Cytoplasmic Alteration Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 119 735 29 1 Cytoplasmic Alteration Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 120 736 29 1 Cytoplasmic Alteration Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 120 737 29 1 Cytoplasmic Alteration Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 120 738 29 1 Cytoplasmic Alteration Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 120 739 29 1 Cytoplasmic Alteration Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 120 740 29 1 Cytoplasmic Alteration Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 5 mg/kg 10 121 741 24 1 Cytoplasmic Alteration Mild Natural Death
Alimentary System Liver Hepatocyte 5 mg/kg 10 121 742 25 1 Cytoplasmic Alteration Marked Natural Death
Alimentary System Liver Hepatocyte 5 mg/kg 10 121 743 24 1 Cytoplasmic Alteration Minimal Natural Death
Alimentary System Liver Hepatocyte 5 mg/kg 10 121 745 24 1 Cytoplasmic Alteration Moderate Natural Death
Alimentary System Liver Hepatocyte 5 mg/kg 10 122 746 25 1 Cytoplasmic Alteration Mild Natural Death
Alimentary System Liver Hepatocyte 5 mg/kg 10 122 749 26 1 Cytoplasmic Alteration Marked Natural Death
Alimentary System Liver Hepatocyte 5 mg/kg 10 122 750 24 1 Cytoplasmic Alteration Marked Natural Death
Alimentary System Liver Hepatocyte 5 mg/kg 10 121 744 29 1 Cytoplasmic Alteration Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 5 mg/kg 10 122 747 29 1 Cytoplasmic Alteration Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 10 mg/kg 10 123 751 15 1 Cytoplasmic Alteration Moderate Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 123 752 17 1 Cytoplasmic Alteration Mild Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 123 753 15 1 Cytoplasmic Alteration Mild Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 123 754 17 1 Cytoplasmic Alteration Mild Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 123 755 17 1 Cytoplasmic Alteration Mild Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 124 756 16 1 Cytoplasmic Alteration Mild Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 124 757 17 1 Cytoplasmic Alteration Mild Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 124 758 17 1 Cytoplasmic Alteration Moderate Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 124 759 18 1 Cytoplasmic Alteration Mild Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 124 760 16 1 Cytoplasmic Alteration Minimal Natural Death
Alimentary System Liver Hepatocyte 0.625 mg/kg 10 115 713 29 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 0.625 mg/kg 10 115 714 29 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 0.625 mg/kg 10 115 715 29 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 0.625 mg/kg 10 116 717 29 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 0.625 mg/kg 10 116 718 29 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 0.625 mg/kg 10 116 719 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 0.625 mg/kg 10 116 720 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 117 721 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 117 722 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 117 723 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 117 724 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 117 725 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 118 726 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 118 727 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 118 728 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 118 729 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 118 730 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 119 731 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 119 732 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 119 733 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 119 734 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 119 735 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 120 736 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 120 737 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 120 738 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 120 739 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 120 740 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 5 mg/kg 10 121 741 24 1 Hypertrophy Marked Natural Death
Alimentary System Liver Hepatocyte 5 mg/kg 10 121 742 25 1 Hypertrophy Marked Natural Death
Alimentary System Liver Hepatocyte 5 mg/kg 10 121 743 24 1 Hypertrophy Mild Natural Death
Alimentary System Liver Hepatocyte 5 mg/kg 10 121 745 24 1 Hypertrophy Moderate Natural Death
Alimentary System Liver Hepatocyte 5 mg/kg 10 122 746 25 1 Hypertrophy Moderate Natural Death
Alimentary System Liver Hepatocyte 5 mg/kg 10 122 749 26 1 Hypertrophy Marked Natural Death
Alimentary System Liver Hepatocyte 5 mg/kg 10 122 750 24 1 Hypertrophy Marked Natural Death
Alimentary System Liver Hepatocyte 5 mg/kg 10 121 744 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 5 mg/kg 10 122 747 29 1 Hypertrophy Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 10 mg/kg 10 123 751 15 1 Hypertrophy Moderate Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 123 752 17 1 Hypertrophy Moderate Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 123 753 15 1 Hypertrophy Moderate Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 123 754 17 1 Hypertrophy Moderate Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 123 755 17 1 Hypertrophy Moderate Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 124 756 16 1 Hypertrophy Moderate Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 124 757 17 1 Hypertrophy Moderate Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 124 758 17 1 Hypertrophy Moderate Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 124 759 18 1 Hypertrophy Moderate Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 124 760 16 1 Hypertrophy Moderate Natural Death
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 117 722 29 1 Necrosis Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 119 731 29 1 Necrosis Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 119 732 29 1 Necrosis Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 119 735 29 1 Necrosis Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 120 736 29 1 Necrosis Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 120 740 29 1 Necrosis Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 5 mg/kg 10 121 743 24 1 Necrosis Mild Natural Death
Alimentary System Liver Hepatocyte 5 mg/kg 10 121 745 24 1 Necrosis Mild Natural Death
Alimentary System Liver Hepatocyte 5 mg/kg 10 122 746 25 1 Necrosis Mild Natural Death
Alimentary System Liver Hepatocyte 5 mg/kg 10 122 749 26 1 Necrosis Mild Natural Death
Alimentary System Liver Hepatocyte 5 mg/kg 10 122 750 24 1 Necrosis Mild Natural Death
Alimentary System Liver Hepatocyte 5 mg/kg 10 121 744 29 1 Necrosis Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 10 mg/kg 10 123 752 17 1 Necrosis Minimal Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 123 753 15 1 Necrosis Mild Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 123 754 17 1 Necrosis Mild Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 123 755 17 1 Necrosis Mild Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 124 756 16 1 Necrosis Mild Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 124 757 17 1 Necrosis Mild Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 124 758 17 1 Necrosis Mild Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 124 759 18 1 Necrosis Minimal Natural Death
Alimentary System Liver Hepatocyte 10 mg/kg 10 124 760 16 1 Necrosis Mild Natural Death
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 117 722 29 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 117 723 29 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 117 724 29 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 117 725 29 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 118 727 29 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 1.25 mg/kg 10 118 728 29 1 Vacuolization Cytoplasmic Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 119 731 29 1 Vacuolization Cytoplasmic Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 119 732 29 1 Vacuolization Cytoplasmic Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 119 734 29 1 Vacuolization Cytoplasmic Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 119 735 29 1 Vacuolization Cytoplasmic Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 120 736 29 1 Vacuolization Cytoplasmic Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 120 737 29 1 Vacuolization Cytoplasmic Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 120 738 29 1 Vacuolization Cytoplasmic Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 120 739 29 1 Vacuolization Cytoplasmic Marked Terminal Sacrifice
Alimentary System Liver Hepatocyte 2.5 mg/kg 10 120 740 29 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 114 706 29 1 Infiltration Cellular Minimal, Mixed Cell Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 114 708 29 1 Infiltration Cellular Minimal, Mixed Cell Terminal Sacrifice
Alimentary System Liver 1.25 mg/kg 10 117 722 29 1 Infiltration Cellular Minimal, Mixed Cell Terminal Sacrifice
Alimentary System Liver 5 mg/kg 10 122 747 29 1 Infiltration Cellular Minimal, Mixed Cell Terminal Sacrifice
Alimentary System Stomach, Forestomach Epithelium 2.5 mg/kg 10 119 731 29 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach, Forestomach Epithelium 2.5 mg/kg 10 119 732 29 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach, Forestomach Epithelium 2.5 mg/kg 10 120 737 29 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach, Forestomach Epithelium 2.5 mg/kg 10 120 738 29 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach, Forestomach Epithelium 2.5 mg/kg 10 120 739 29 1 Hyperplasia Marked Terminal Sacrifice
Alimentary System Stomach, Forestomach Epithelium 2.5 mg/kg 10 120 740 29 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach, Forestomach Epithelium 5 mg/kg 10 121 742 25 1 Hyperplasia Minimal Natural Death
Alimentary System Stomach, Forestomach Epithelium 5 mg/kg 10 121 743 24 1 Hyperplasia Mild Natural Death
Alimentary System Stomach, Forestomach Epithelium 5 mg/kg 10 122 746 25 1 Hyperplasia Minimal Natural Death
Alimentary System Stomach, Forestomach Epithelium 5 mg/kg 10 122 749 26 1 Hyperplasia Mild Natural Death
Alimentary System Stomach, Forestomach Epithelium 5 mg/kg 10 122 750 24 1 Hyperplasia Moderate Natural Death
Alimentary System Stomach, Forestomach Epithelium 5 mg/kg 10 122 747 29 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach, Forestomach Epithelium 10 mg/kg 10 123 751 15 1 Hyperplasia Mild Natural Death
Alimentary System Stomach, Forestomach Epithelium 10 mg/kg 10 123 753 15 1 Hyperplasia Minimal Natural Death
Alimentary System Stomach, Forestomach Epithelium 10 mg/kg 10 123 754 17 1 Hyperplasia Mild Natural Death
Alimentary System Stomach, Forestomach Epithelium 10 mg/kg 10 123 755 17 1 Hyperplasia Mild Natural Death
Alimentary System Stomach, Forestomach Epithelium 10 mg/kg 10 124 757 17 1 Hyperplasia Mild Natural Death
Alimentary System Stomach, Forestomach Epithelium 10 mg/kg 10 124 758 17 1 Hyperplasia Minimal Natural Death
Alimentary System Stomach, Forestomach Epithelium 10 mg/kg 10 124 759 18 1 Hyperplasia Mild Natural Death
Alimentary System Stomach, Forestomach Epithelium 10 mg/kg 10 124 760 16 1 Hyperplasia Mild Natural Death
Alimentary System Stomach, Forestomach 2.5 mg/kg 10 119 732 29 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Stomach, Forestomach 2.5 mg/kg 10 120 737 29 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Stomach, Forestomach 2.5 mg/kg 10 120 738 29 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Stomach, Forestomach 2.5 mg/kg 10 120 739 29 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Stomach, Forestomach 2.5 mg/kg 10 120 740 29 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Stomach, Forestomach 2.5 mg/kg 10 120 738 29 1 Ulcer Minimal Terminal Sacrifice
Alimentary System Stomach, Forestomach 2.5 mg/kg 10 120 740 29 1 Ulcer Minimal Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 114 708 29 1 Infiltration Cellular Minimal, Mixed Cell Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 114 709 29 1 Infiltration Cellular Minimal, Mixed Cell Terminal Sacrifice
Genital System Epididymis Duct 2.5 mg/kg 10 119 731 29 1 Exfoliated Germ Cell Moderate Terminal Sacrifice
Genital System Epididymis Duct 2.5 mg/kg 10 119 732 29 1 Exfoliated Germ Cell Mild Terminal Sacrifice
Genital System Epididymis Duct 2.5 mg/kg 10 119 735 29 1 Exfoliated Germ Cell Mild Terminal Sacrifice
Genital System Epididymis Duct 2.5 mg/kg 10 120 736 29 1 Exfoliated Germ Cell Moderate Terminal Sacrifice
Genital System Epididymis Duct 2.5 mg/kg 10 120 739 29 1 Exfoliated Germ Cell Mild Terminal Sacrifice
Genital System Epididymis Duct 2.5 mg/kg 10 120 740 29 1 Exfoliated Germ Cell Marked Terminal Sacrifice
Genital System Epididymis Duct 5 mg/kg 10 121 742 25 1 Exfoliated Germ Cell Moderate Natural Death
Genital System Epididymis Duct 5 mg/kg 10 121 743 24 1 Exfoliated Germ Cell Moderate Natural Death
Genital System Epididymis Duct 5 mg/kg 10 121 745 24 1 Exfoliated Germ Cell Marked Natural Death
Genital System Epididymis Duct 5 mg/kg 10 122 746 25 1 Exfoliated Germ Cell Marked Natural Death
Genital System Epididymis Duct 5 mg/kg 10 122 748 25 1 Exfoliated Germ Cell Marked Natural Death
Genital System Epididymis Duct 5 mg/kg 10 122 749 26 1 Exfoliated Germ Cell Marked Natural Death
Genital System Epididymis Duct 5 mg/kg 10 122 750 24 1 Exfoliated Germ Cell Marked Natural Death
Genital System Epididymis Duct 5 mg/kg 10 121 744 29 1 Exfoliated Germ Cell Marked Terminal Sacrifice
Genital System Epididymis Duct 5 mg/kg 10 122 747 29 1 Exfoliated Germ Cell Moderate Terminal Sacrifice
Genital System Epididymis Duct 10 mg/kg 10 123 751 15 1 Exfoliated Germ Cell Moderate Natural Death
Genital System Epididymis Duct 10 mg/kg 10 123 752 17 1 Exfoliated Germ Cell Mild Natural Death
Genital System Epididymis Duct 10 mg/kg 10 123 753 15 1 Exfoliated Germ Cell Moderate Natural Death
Genital System Epididymis Duct 10 mg/kg 10 123 754 17 1 Exfoliated Germ Cell Marked Natural Death
Genital System Epididymis Duct 10 mg/kg 10 123 755 17 1 Exfoliated Germ Cell Marked Natural Death
Genital System Epididymis Duct 10 mg/kg 10 124 756 16 1 Exfoliated Germ Cell Marked Natural Death
Genital System Epididymis Duct 10 mg/kg 10 124 757 17 1 Exfoliated Germ Cell Marked Natural Death
Genital System Epididymis Duct 10 mg/kg 10 124 758 17 1 Exfoliated Germ Cell Marked Natural Death
Genital System Epididymis Duct 10 mg/kg 10 124 759 18 1 Exfoliated Germ Cell Marked Natural Death
Genital System Epididymis Duct 10 mg/kg 10 124 760 16 1 Exfoliated Germ Cell Marked Natural Death
Genital System Epididymis Epithelium 5 mg/kg 10 121 742 25 1 Apoptosis Mild Natural Death
Genital System Epididymis Epithelium 5 mg/kg 10 121 743 24 1 Apoptosis Mild Natural Death
Genital System Epididymis Epithelium 5 mg/kg 10 121 745 24 1 Apoptosis Moderate Natural Death
Genital System Epididymis Epithelium 5 mg/kg 10 122 746 25 1 Apoptosis Mild Natural Death
Genital System Epididymis Epithelium 5 mg/kg 10 122 748 25 1 Apoptosis Mild Natural Death
Genital System Epididymis Epithelium 5 mg/kg 10 122 749 26 1 Apoptosis Minimal Natural Death
Genital System Epididymis Epithelium 5 mg/kg 10 122 750 24 1 Apoptosis Mild Natural Death
Genital System Epididymis Epithelium 5 mg/kg 10 121 744 29 1 Apoptosis Mild Terminal Sacrifice
Genital System Epididymis Epithelium 10 mg/kg 10 123 751 15 1 Apoptosis Moderate Natural Death
Genital System Epididymis Epithelium 10 mg/kg 10 123 752 17 1 Apoptosis Moderate Natural Death
Genital System Epididymis Epithelium 10 mg/kg 10 123 753 15 1 Apoptosis Mild Natural Death
Genital System Epididymis Epithelium 10 mg/kg 10 123 754 17 1 Apoptosis Minimal Natural Death
Genital System Epididymis Epithelium 10 mg/kg 10 123 755 17 1 Apoptosis Minimal Natural Death
Genital System Epididymis Epithelium 10 mg/kg 10 124 756 16 1 Apoptosis Mild Natural Death
Genital System Epididymis Epithelium 10 mg/kg 10 124 757 17 1 Apoptosis Mild Natural Death
Genital System Epididymis Epithelium 10 mg/kg 10 124 758 17 1 Apoptosis Moderate Natural Death
Genital System Epididymis Epithelium 10 mg/kg 10 124 759 18 1 Apoptosis Mild Natural Death
Genital System Epididymis Epithelium 10 mg/kg 10 124 760 16 1 Apoptosis Mild Natural Death
Genital System Epididymis Epithelium 5 mg/kg 10 122 746 25 1 Exfoliated Germ Cell Mild Natural Death
Genital System Epididymis 10 mg/kg 10 123 751 15 1 Granuloma Sperm Mild Natural Death
Genital System Epididymis 10 mg/kg 10 123 752 17 1 Granuloma Sperm Mild Natural Death
Genital System Epididymis 10 mg/kg 10 123 755 17 1 Granuloma Sperm Mild Natural Death
Genital System Epididymis 10 mg/kg 10 124 760 16 1 Granuloma Sperm Mild Natural Death
Genital System Epididymis 2.5 mg/kg 10 119 731 29 1 Hypospermia Mild Terminal Sacrifice
Genital System Epididymis 2.5 mg/kg 10 120 740 29 1 Hypospermia Moderate Terminal Sacrifice
Genital System Epididymis 5 mg/kg 10 121 742 25 1 Hypospermia Moderate Natural Death
Genital System Epididymis 5 mg/kg 10 121 743 24 1 Hypospermia Moderate Natural Death
Genital System Epididymis 5 mg/kg 10 121 745 24 1 Hypospermia Marked Natural Death
Genital System Epididymis 5 mg/kg 10 122 746 25 1 Hypospermia Marked Natural Death
Genital System Epididymis 5 mg/kg 10 122 748 25 1 Hypospermia Marked Natural Death
Genital System Epididymis 5 mg/kg 10 122 749 26 1 Hypospermia Marked Natural Death
Genital System Epididymis 5 mg/kg 10 122 750 24 1 Hypospermia Marked Natural Death
Genital System Epididymis 5 mg/kg 10 121 744 29 1 Hypospermia Marked Terminal Sacrifice
Genital System Epididymis 5 mg/kg 10 122 747 29 1 Hypospermia Moderate Terminal Sacrifice
Genital System Epididymis 10 mg/kg 10 123 751 15 1 Hypospermia Moderate Natural Death
Genital System Epididymis 10 mg/kg 10 123 752 17 1 Hypospermia Moderate Natural Death
Genital System Epididymis 10 mg/kg 10 123 753 15 1 Hypospermia Mild Natural Death
Genital System Epididymis 10 mg/kg 10 123 754 17 1 Hypospermia Moderate Natural Death
Genital System Epididymis 10 mg/kg 10 123 755 17 1 Hypospermia Moderate Natural Death
Genital System Epididymis 10 mg/kg 10 124 756 16 1 Hypospermia Moderate Natural Death
Genital System Epididymis 10 mg/kg 10 124 757 17 1 Hypospermia Moderate Natural Death
Genital System Epididymis 10 mg/kg 10 124 758 17 1 Hypospermia Moderate Natural Death
Genital System Epididymis 10 mg/kg 10 124 759 18 1 Hypospermia Moderate Natural Death
Genital System Epididymis 10 mg/kg 10 124 760 16 1 Hypospermia Moderate Natural Death
Genital System Testes Germinal Epith 2.5 mg/kg 10 119 731 29 1 Degeneration Mild Terminal Sacrifice
Genital System Testes Germinal Epith 2.5 mg/kg 10 119 732 29 1 Degeneration Minimal Terminal Sacrifice
Genital System Testes Germinal Epith 2.5 mg/kg 10 119 735 29 1 Degeneration Mild Terminal Sacrifice
Genital System Testes Germinal Epith 2.5 mg/kg 10 120 736 29 1 Degeneration Mild Terminal Sacrifice
Genital System Testes Germinal Epith 2.5 mg/kg 10 120 739 29 1 Degeneration Mild Terminal Sacrifice
Genital System Testes Germinal Epith 2.5 mg/kg 10 120 740 29 1 Degeneration Marked Terminal Sacrifice
Genital System Testes Germinal Epith 5 mg/kg 10 121 742 25 1 Degeneration Moderate Natural Death
Genital System Testes Germinal Epith 5 mg/kg 10 121 743 24 1 Degeneration Mild Natural Death
Genital System Testes Germinal Epith 5 mg/kg 10 121 745 24 1 Degeneration Moderate Natural Death
Genital System Testes Germinal Epith 5 mg/kg 10 122 746 25 1 Degeneration Moderate Natural Death
Genital System Testes Germinal Epith 5 mg/kg 10 122 748 25 1 Degeneration Marked Natural Death
Genital System Testes Germinal Epith 5 mg/kg 10 122 749 26 1 Degeneration Moderate Natural Death
Genital System Testes Germinal Epith 5 mg/kg 10 122 750 24 1 Degeneration Marked Natural Death
Genital System Testes Germinal Epith 5 mg/kg 10 121 744 29 1 Degeneration Moderate Terminal Sacrifice
Genital System Testes Germinal Epith 5 mg/kg 10 122 747 29 1 Degeneration Moderate Terminal Sacrifice
Genital System Testes Germinal Epith 10 mg/kg 10 123 751 15 1 Degeneration Marked Natural Death
Genital System Testes Germinal Epith 10 mg/kg 10 123 752 17 1 Degeneration Marked Natural Death
Genital System Testes Germinal Epith 10 mg/kg 10 123 753 15 1 Degeneration Moderate Natural Death
Genital System Testes Germinal Epith 10 mg/kg 10 123 754 17 1 Degeneration Marked Natural Death
Genital System Testes Germinal Epith 10 mg/kg 10 123 755 17 1 Degeneration Marked Natural Death
Genital System Testes Germinal Epith 10 mg/kg 10 124 756 16 1 Degeneration Marked Natural Death
Genital System Testes Germinal Epith 10 mg/kg 10 124 757 17 1 Degeneration Moderate Natural Death
Genital System Testes Germinal Epith 10 mg/kg 10 124 758 17 1 Degeneration Marked Natural Death
Genital System Testes Germinal Epith 10 mg/kg 10 124 759 18 1 Degeneration Moderate Natural Death
Genital System Testes Germinal Epith 10 mg/kg 10 124 760 16 1 Degeneration Marked Natural Death
Genital System Testes Interstit Cell 1.25 mg/kg 10 118 727 29 1 Atrophy Minimal Terminal Sacrifice
Genital System Testes Interstit Cell 2.5 mg/kg 10 119 731 29 1 Atrophy Mild Terminal Sacrifice
Genital System Testes Interstit Cell 2.5 mg/kg 10 119 732 29 1 Atrophy Mild Terminal Sacrifice
Genital System Testes Interstit Cell 2.5 mg/kg 10 119 733 29 1 Atrophy Minimal Terminal Sacrifice
Genital System Testes Interstit Cell 2.5 mg/kg 10 119 734 29 1 Atrophy Minimal Terminal Sacrifice
Genital System Testes Interstit Cell 2.5 mg/kg 10 119 735 29 1 Atrophy Mild Terminal Sacrifice
Genital System Testes Interstit Cell 2.5 mg/kg 10 120 736 29 1 Atrophy Mild Terminal Sacrifice
Genital System Testes Interstit Cell 2.5 mg/kg 10 120 737 29 1 Atrophy Mild Terminal Sacrifice
Genital System Testes Interstit Cell 2.5 mg/kg 10 120 738 29 1 Atrophy Minimal Terminal Sacrifice
Genital System Testes Interstit Cell 2.5 mg/kg 10 120 739 29 1 Atrophy Mild Terminal Sacrifice
Genital System Testes Interstit Cell 2.5 mg/kg 10 120 740 29 1 Atrophy Mild Terminal Sacrifice
Genital System Testes Interstit Cell 5 mg/kg 10 121 742 25 1 Atrophy Moderate Natural Death
Genital System Testes Interstit Cell 5 mg/kg 10 121 743 24 1 Atrophy Moderate Natural Death
Genital System Testes Interstit Cell 5 mg/kg 10 121 745 24 1 Atrophy Moderate Natural Death
Genital System Testes Interstit Cell 5 mg/kg 10 122 746 25 1 Atrophy Moderate Natural Death
Genital System Testes Interstit Cell 5 mg/kg 10 122 748 25 1 Atrophy Marked Natural Death
Genital System Testes Interstit Cell 5 mg/kg 10 122 749 26 1 Atrophy Moderate Natural Death
Genital System Testes Interstit Cell 5 mg/kg 10 122 750 24 1 Atrophy Moderate Natural Death
Genital System Testes Interstit Cell 5 mg/kg 10 121 744 29 1 Atrophy Moderate Terminal Sacrifice
Genital System Testes Interstit Cell 5 mg/kg 10 122 747 29 1 Atrophy Moderate Terminal Sacrifice
Genital System Testes Interstit Cell 10 mg/kg 10 123 751 15 1 Atrophy Moderate Natural Death
Genital System Testes Interstit Cell 10 mg/kg 10 123 752 17 1 Atrophy Moderate Natural Death
Genital System Testes Interstit Cell 10 mg/kg 10 123 753 15 1 Atrophy Moderate Natural Death
Genital System Testes Interstit Cell 10 mg/kg 10 123 754 17 1 Atrophy Marked Natural Death
Genital System Testes Interstit Cell 10 mg/kg 10 123 755 17 1 Atrophy Marked Natural Death
Genital System Testes Interstit Cell 10 mg/kg 10 124 756 16 1 Atrophy Marked Natural Death
Genital System Testes Interstit Cell 10 mg/kg 10 124 757 17 1 Atrophy Moderate Natural Death
Genital System Testes Interstit Cell 10 mg/kg 10 124 758 17 1 Atrophy Marked Natural Death
Genital System Testes Interstit Cell 10 mg/kg 10 124 759 18 1 Atrophy Moderate Natural Death
Genital System Testes Interstit Cell 10 mg/kg 10 124 760 16 1 Atrophy Marked Natural Death
Genital System Testes Seminif Tub 2.5 mg/kg 10 119 731 29 1 Spermatid Retention Moderate Terminal Sacrifice
Genital System Testes Seminif Tub 2.5 mg/kg 10 119 732 29 1 Spermatid Retention Moderate Terminal Sacrifice
Genital System Testes Seminif Tub 2.5 mg/kg 10 119 735 29 1 Spermatid Retention Moderate Terminal Sacrifice
Genital System Testes Seminif Tub 2.5 mg/kg 10 120 736 29 1 Spermatid Retention Moderate Terminal Sacrifice
Genital System Testes Seminif Tub 2.5 mg/kg 10 120 739 29 1 Spermatid Retention Mild Terminal Sacrifice
Genital System Testes Seminif Tub 2.5 mg/kg 10 120 740 29 1 Spermatid Retention Moderate Terminal Sacrifice
Genital System Testes Seminif Tub 5 mg/kg 10 121 742 25 1 Spermatid Retention Moderate Natural Death
Genital System Testes Seminif Tub 5 mg/kg 10 121 743 24 1 Spermatid Retention Moderate Natural Death
Genital System Testes Seminif Tub 5 mg/kg 10 121 745 24 1 Spermatid Retention Moderate Natural Death
Genital System Testes Seminif Tub 5 mg/kg 10 122 746 25 1 Spermatid Retention Moderate Natural Death
Genital System Testes Seminif Tub 5 mg/kg 10 122 748 25 1 Spermatid Retention Moderate Natural Death
Genital System Testes Seminif Tub 5 mg/kg 10 122 749 26 1 Spermatid Retention Moderate Natural Death
Genital System Testes Seminif Tub 5 mg/kg 10 122 750 24 1 Spermatid Retention Moderate Natural Death
Genital System Testes Seminif Tub 5 mg/kg 10 121 744 29 1 Spermatid Retention Moderate Terminal Sacrifice
Genital System Testes Seminif Tub 5 mg/kg 10 122 747 29 1 Spermatid Retention Moderate Terminal Sacrifice
Genital System Testes Seminif Tub 10 mg/kg 10 123 751 15 1 Spermatid Retention Moderate Natural Death
Genital System Testes Seminif Tub 10 mg/kg 10 123 752 17 1 Spermatid Retention Moderate Natural Death
Genital System Testes Seminif Tub 10 mg/kg 10 123 753 15 1 Spermatid Retention Moderate Natural Death
Genital System Testes Seminif Tub 10 mg/kg 10 123 754 17 1 Spermatid Retention Moderate Natural Death
Genital System Testes Seminif Tub 10 mg/kg 10 123 755 17 1 Spermatid Retention Moderate Natural Death
Genital System Testes Seminif Tub 10 mg/kg 10 124 756 16 1 Spermatid Retention Moderate Natural Death
Genital System Testes Seminif Tub 10 mg/kg 10 124 757 17 1 Spermatid Retention Moderate Natural Death
Genital System Testes Seminif Tub 10 mg/kg 10 124 758 17 1 Spermatid Retention Moderate Natural Death
Genital System Testes Seminif Tub 10 mg/kg 10 124 759 18 1 Spermatid Retention Moderate Natural Death
Genital System Testes Seminif Tub 10 mg/kg 10 124 760 16 1 Spermatid Retention Moderate Natural Death
Hematopoietic System Bone Marrow 2.5 mg/kg 10 119 731 29 1 Hypocellularity Moderate Terminal Sacrifice
Hematopoietic System Bone Marrow 2.5 mg/kg 10 119 732 29 1 Hypocellularity Moderate Terminal Sacrifice
Hematopoietic System Bone Marrow 2.5 mg/kg 10 119 733 29 1 Hypocellularity Moderate Terminal Sacrifice
Hematopoietic System Bone Marrow 2.5 mg/kg 10 119 734 29 1 Hypocellularity Marked Terminal Sacrifice
Hematopoietic System Bone Marrow 2.5 mg/kg 10 119 735 29 1 Hypocellularity Moderate Terminal Sacrifice
Hematopoietic System Bone Marrow 2.5 mg/kg 10 120 736 29 1 Hypocellularity Marked Terminal Sacrifice
Hematopoietic System Bone Marrow 2.5 mg/kg 10 120 737 29 1 Hypocellularity Marked Terminal Sacrifice
Hematopoietic System Bone Marrow 2.5 mg/kg 10 120 738 29 1 Hypocellularity Moderate Terminal Sacrifice
Hematopoietic System Bone Marrow 2.5 mg/kg 10 120 739 29 1 Hypocellularity Moderate Terminal Sacrifice
Hematopoietic System Bone Marrow 2.5 mg/kg 10 120 740 29 1 Hypocellularity Marked Terminal Sacrifice
Hematopoietic System Bone Marrow 5 mg/kg 10 121 741 24 1 Hypocellularity Marked Natural Death
Hematopoietic System Bone Marrow 5 mg/kg 10 121 742 25 1 Hypocellularity Marked Natural Death
Hematopoietic System Bone Marrow 5 mg/kg 10 121 743 24 1 Hypocellularity Marked Natural Death
Hematopoietic System Bone Marrow 5 mg/kg 10 121 745 24 1 Hypocellularity Marked Natural Death
Hematopoietic System Bone Marrow 5 mg/kg 10 122 746 25 1 Hypocellularity Marked Natural Death
Hematopoietic System Bone Marrow 5 mg/kg 10 122 748 25 1 Hypocellularity Marked Natural Death
Hematopoietic System Bone Marrow 5 mg/kg 10 122 749 26 1 Hypocellularity Marked Natural Death
Hematopoietic System Bone Marrow 5 mg/kg 10 122 750 24 1 Hypocellularity Marked Natural Death
Hematopoietic System Bone Marrow 5 mg/kg 10 121 744 29 1 Hypocellularity Marked Terminal Sacrifice
Hematopoietic System Bone Marrow 5 mg/kg 10 122 747 29 1 Hypocellularity Marked Terminal Sacrifice
Hematopoietic System Bone Marrow 10 mg/kg 10 123 751 15 1 Hypocellularity Moderate Natural Death
Hematopoietic System Bone Marrow 10 mg/kg 10 123 752 17 1 Hypocellularity Moderate Natural Death
Hematopoietic System Bone Marrow 10 mg/kg 10 123 753 15 1 Hypocellularity Moderate Natural Death
Hematopoietic System Bone Marrow 10 mg/kg 10 123 754 17 1 Hypocellularity Moderate Natural Death
Hematopoietic System Bone Marrow 10 mg/kg 10 123 755 17 1 Hypocellularity Moderate Natural Death
Hematopoietic System Bone Marrow 10 mg/kg 10 124 756 16 1 Hypocellularity Moderate Natural Death
Hematopoietic System Bone Marrow 10 mg/kg 10 124 757 17 1 Hypocellularity Moderate Natural Death
Hematopoietic System Bone Marrow 10 mg/kg 10 124 758 17 1 Hypocellularity Moderate Natural Death
Hematopoietic System Bone Marrow 10 mg/kg 10 124 759 18 1 Hypocellularity Moderate Natural Death
Hematopoietic System Bone Marrow 10 mg/kg 10 124 760 16 1 Hypocellularity Marked Natural Death
Hematopoietic System Lymph Node Mandibular 2.5 mg/kg 10 120 739 29 1 Atrophy Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 2.5 mg/kg 10 120 740 29 1 Atrophy Mild Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 5 mg/kg 10 121 741 24 1 Atrophy Marked Natural Death
Hematopoietic System Lymph Node Mandibular 5 mg/kg 10 121 745 24 1 Atrophy Moderate Natural Death
Hematopoietic System Lymph Node Mandibular 5 mg/kg 10 122 746 25 1 Atrophy Marked Natural Death
Hematopoietic System Lymph Node Mandibular 5 mg/kg 10 122 748 25 1 Atrophy Marked Natural Death
Hematopoietic System Lymph Node Mandibular 5 mg/kg 10 122 749 26 1 Atrophy Marked Natural Death
Hematopoietic System Lymph Node Mandibular 10 mg/kg 10 123 752 17 1 Atrophy Mild Natural Death
Hematopoietic System Lymph Node Mandibular 10 mg/kg 10 124 757 17 1 Atrophy Mild Natural Death
Hematopoietic System Lymph Node Mandibular 10 mg/kg 10 124 758 17 1 Atrophy Mild Natural Death
Hematopoietic System Lymph Node Mandibular 10 mg/kg 10 124 759 18 1 Atrophy Mild Natural Death
Hematopoietic System Lymph Node Mandibular 10 mg/kg 10 124 760 16 1 Atrophy Moderate Natural Death
Hematopoietic System Lymph Node Mesenteric 2.5 mg/kg 10 119 731 29 1 Atrophy Mild Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 2.5 mg/kg 10 120 736 29 1 Atrophy Marked Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 2.5 mg/kg 10 120 739 29 1 Atrophy Moderate Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 5 mg/kg 10 121 742 25 1 Atrophy Marked Natural Death
Hematopoietic System Lymph Node Mesenteric 5 mg/kg 10 121 743 24 1 Atrophy Marked Natural Death
Hematopoietic System Lymph Node Mesenteric 5 mg/kg 10 121 745 24 1 Atrophy Moderate Natural Death
Hematopoietic System Lymph Node Mesenteric 5 mg/kg 10 122 746 25 1 Atrophy Marked Natural Death
Hematopoietic System Lymph Node Mesenteric 5 mg/kg 10 122 749 26 1 Atrophy Moderate Natural Death
Hematopoietic System Lymph Node Mesenteric 5 mg/kg 10 122 750 24 1 Atrophy Marked Natural Death
Hematopoietic System Lymph Node Mesenteric 10 mg/kg 10 123 751 15 1 Atrophy Moderate Natural Death
Hematopoietic System Lymph Node Mesenteric 10 mg/kg 10 123 752 17 1 Atrophy Marked Natural Death
Hematopoietic System Lymph Node Mesenteric 10 mg/kg 10 123 754 17 1 Atrophy Moderate Natural Death
Hematopoietic System Lymph Node Mesenteric 10 mg/kg 10 123 755 17 1 Atrophy Marked Natural Death
Hematopoietic System Lymph Node Mesenteric 10 mg/kg 10 124 756 16 1 Atrophy Marked Natural Death
Hematopoietic System Lymph Node Mesenteric 10 mg/kg 10 124 757 17 1 Atrophy Mild Natural Death
Hematopoietic System Lymph Node Mesenteric 10 mg/kg 10 124 758 17 1 Atrophy Marked Natural Death
Hematopoietic System Lymph Node Mesenteric 10 mg/kg 10 124 759 18 1 Atrophy Moderate Natural Death
Hematopoietic System Lymph Node Mesenteric 10 mg/kg 10 124 760 16 1 Atrophy Mild Natural Death
Hematopoietic System Spleen 5 mg/kg 10 121 742 25 1 Atrophy Marked Natural Death
Hematopoietic System Spleen 5 mg/kg 10 121 743 24 1 Atrophy Marked Natural Death
Hematopoietic System Spleen 5 mg/kg 10 121 745 24 1 Atrophy Marked Natural Death
Hematopoietic System Spleen 5 mg/kg 10 122 746 25 1 Atrophy Marked Natural Death
Hematopoietic System Spleen 5 mg/kg 10 122 749 26 1 Atrophy Marked Natural Death
Hematopoietic System Spleen 5 mg/kg 10 122 750 24 1 Atrophy Marked Natural Death
Hematopoietic System Spleen 5 mg/kg 10 122 747 29 1 Atrophy Minimal Terminal Sacrifice
Hematopoietic System Spleen 10 mg/kg 10 123 751 15 1 Atrophy Marked Natural Death
Hematopoietic System Spleen 10 mg/kg 10 123 752 17 1 Atrophy Marked Natural Death
Hematopoietic System Spleen 10 mg/kg 10 123 753 15 1 Atrophy Marked Natural Death
Hematopoietic System Spleen 10 mg/kg 10 123 754 17 1 Atrophy Marked Natural Death
Hematopoietic System Spleen 10 mg/kg 10 124 756 16 1 Atrophy Marked Natural Death
Hematopoietic System Spleen 10 mg/kg 10 124 757 17 1 Atrophy Marked Natural Death
Hematopoietic System Spleen 10 mg/kg 10 124 758 17 1 Atrophy Marked Natural Death
Hematopoietic System Spleen 10 mg/kg 10 124 759 18 1 Atrophy Marked Natural Death
Hematopoietic System Spleen 10 mg/kg 10 124 760 16 1 Atrophy Marked Natural Death
Hematopoietic System Thymus 2.5 mg/kg 10 119 731 29 1 Atrophy Marked Terminal Sacrifice
Hematopoietic System Thymus 2.5 mg/kg 10 119 732 29 1 Atrophy Marked Terminal Sacrifice
Hematopoietic System Thymus 2.5 mg/kg 10 119 733 29 1 Atrophy Mild Terminal Sacrifice
Hematopoietic System Thymus 2.5 mg/kg 10 119 734 29 1 Atrophy Mild Terminal Sacrifice
Hematopoietic System Thymus 2.5 mg/kg 10 119 735 29 1 Atrophy Marked Terminal Sacrifice
Hematopoietic System Thymus 2.5 mg/kg 10 120 736 29 1 Atrophy Marked Terminal Sacrifice
Hematopoietic System Thymus 2.5 mg/kg 10 120 737 29 1 Atrophy Moderate Terminal Sacrifice
Hematopoietic System Thymus 2.5 mg/kg 10 120 738 29 1 Atrophy Mild Terminal Sacrifice
Hematopoietic System Thymus 2.5 mg/kg 10 120 739 29 1 Atrophy Marked Terminal Sacrifice
Hematopoietic System Thymus 2.5 mg/kg 10 120 740 29 1 Atrophy Marked Terminal Sacrifice
Hematopoietic System Thymus 5 mg/kg 10 121 741 24 1 Atrophy Marked Natural Death
Hematopoietic System Thymus 5 mg/kg 10 121 742 25 1 Atrophy Marked Natural Death
Hematopoietic System Thymus 5 mg/kg 10 121 743 24 1 Atrophy Marked Natural Death
Hematopoietic System Thymus 5 mg/kg 10 121 745 24 1 Atrophy Marked Natural Death
Hematopoietic System Thymus 5 mg/kg 10 122 746 25 1 Atrophy Marked Natural Death
Hematopoietic System Thymus 5 mg/kg 10 122 748 25 1 Atrophy Marked Natural Death
Hematopoietic System Thymus 5 mg/kg 10 122 749 26 1 Atrophy Marked Natural Death
Hematopoietic System Thymus 5 mg/kg 10 122 750 24 1 Atrophy Marked Natural Death
Hematopoietic System Thymus 5 mg/kg 10 121 744 29 1 Atrophy Marked Terminal Sacrifice
Hematopoietic System Thymus 5 mg/kg 10 122 747 29 1 Atrophy Marked Terminal Sacrifice
Hematopoietic System Thymus 10 mg/kg 10 123 751 15 1 Atrophy Marked Natural Death
Hematopoietic System Thymus 10 mg/kg 10 123 753 15 1 Atrophy Marked Natural Death
Hematopoietic System Thymus 10 mg/kg 10 123 754 17 1 Atrophy Marked Natural Death
Hematopoietic System Thymus 10 mg/kg 10 123 755 17 1 Atrophy Marked Natural Death
Hematopoietic System Thymus 10 mg/kg 10 124 756 16 1 Atrophy Marked Natural Death
Hematopoietic System Thymus 10 mg/kg 10 124 757 17 1 Atrophy Marked Natural Death
Hematopoietic System Thymus 10 mg/kg 10 124 758 17 1 Atrophy Marked Natural Death
Hematopoietic System Thymus 10 mg/kg 10 124 759 18 1 Atrophy Marked Natural Death
Respiratory System Lung Artery 5 mg/kg 10 121 743 24 1 Thrombus Mild, Focal Natural Death
Respiratory System Lung Vehicle Control 10 113 702 29 1 Infiltration Cellular Minimal, Mixed Cell Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 113 704 29 1 Infiltration Cellular Minimal, Mixed Cell Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 114 708 29 1 Infiltration Cellular Minimal, Mixed Cell Terminal Sacrifice
Respiratory System Lung 10 mg/kg 10 123 752 17 1 Infiltration Cellular Minimal, Mixed Cell Natural Death
Respiratory System Nose Olfactory Epi 5 mg/kg 10 122 748 25 1 Degeneration Minimal Natural Death
Respiratory System Nose Olfactory Epi 10 mg/kg 10 123 752 17 1 Degeneration Minimal Natural Death
Respiratory System Nose Olfactory Epi 10 mg/kg 10 124 757 17 1 Degeneration Mild Natural Death
Respiratory System Nose Olfactory Epi 10 mg/kg 10 124 758 17 1 Degeneration Minimal Natural Death
Respiratory System Nose Olfactory Epi 5 mg/kg 10 122 748 25 1 Inflammation Mild, Suppurative Natural Death
Respiratory System Nose Olfactory Epi 10 mg/kg 10 123 752 17 1 Inflammation Mild, Suppurative Natural Death
Respiratory System Nose Olfactory Epi 10 mg/kg 10 124 757 17 1 Inflammation Mild, Suppurative Natural Death
Respiratory System Nose Respirat Epith 10 mg/kg 10 124 757 17 1 Hyperplasia Minimal Natural Death
Respiratory System Nose Respirat Epith Vehicle Control 10 113 701 29 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Respiratory System Nose Respirat Epith 0.625 mg/kg 10 116 716 29 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Respiratory System Nose Respirat Epith 0.625 mg/kg 10 116 717 29 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Respiratory System Nose Respirat Epith 0.625 mg/kg 10 116 718 29 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Respiratory System Nose Respirat Epith 0.625 mg/kg 10 116 719 29 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Respiratory System Nose Respirat Epith 0.625 mg/kg 10 116 720 29 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 113 702 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 113 703 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 113 704 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 113 705 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 114 706 29 1 Nephropathy Mild, Chronicprogr Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 114 707 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 114 708 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 114 709 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney 0.625 mg/kg 10 115 711 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney 0.625 mg/kg 10 115 712 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney 0.625 mg/kg 10 115 713 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney 0.625 mg/kg 10 115 714 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney 0.625 mg/kg 10 115 715 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney 0.625 mg/kg 10 116 716 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney 0.625 mg/kg 10 116 719 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney 0.625 mg/kg 10 116 720 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney 1.25 mg/kg 10 117 721 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney 1.25 mg/kg 10 117 724 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney 1.25 mg/kg 10 118 726 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney 1.25 mg/kg 10 118 728 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney 1.25 mg/kg 10 118 730 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney 2.5 mg/kg 10 119 731 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney 2.5 mg/kg 10 119 732 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney 2.5 mg/kg 10 119 733 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney 2.5 mg/kg 10 120 736 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney 2.5 mg/kg 10 120 738 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney 2.5 mg/kg 10 120 740 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice
Urinary System Kidney 5 mg/kg 10 122 746 25 1 Nephropathy Minimal, Chronicprogr Natural Death
Urinary System Kidney 5 mg/kg 10 122 749 26 1 Nephropathy Minimal, Chronicprogr Natural Death
Urinary System Kidney 5 mg/kg 10 122 750 24 1 Nephropathy Minimal, Chronicprogr Natural Death
Urinary System Kidney 5 mg/kg 10 122 747 29 1 Nephropathy Minimal, Chronicprogr Terminal Sacrifice