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Short-Term Study Individual Animal Clinical Observations

Study Information:

Chemical Name: Perfluorobutane sulfonate (PFBS)
CASRN: ="375-73-5"
Study Number: C07040
Exposure Route: GAVAGE
TDMS Number: 0704001
Sex: Female
Strain and Species: HSD Rats

Animal Number Dose Group Clinical Observation Qualifier Incident Number Observation Date First Dose Date Days On Study Removal Observation
245 250 mg/kg Clonic Seizures 02/17/2012 01/20/12 29.00 Yes
251 500 mg/kg Clonic Seizures 02/17/2012 01/20/12 29.00 Yes
260 500 mg/kg Clonic Seizures 02/17/2012 01/20/12 29.00 Yes
264 1000 mg/kg Tonic Seizures 02/17/2012 01/20/12 29.00 Yes
265 1000 mg/kg Thin 02/17/2012 01/20/12 29.00 Yes
266 1000 mg/kg Lethargic 02/02/2012 01/20/12 14.00 No
267 1000 mg/kg Ruffled Fur 01/30/2012 01/20/12 11.00 No
267 1000 mg/kg Thin 02/03/2012 01/20/12 15.00 No
267 1000 mg/kg Thin 02/04/2012 01/20/12 16.00 Yes
268 1000 mg/kg Thin 02/10/2012 01/20/12 22.00 No
268 1000 mg/kg Thin 02/11/2012 01/20/12 23.00 Yes
268 1000 mg/kg Nasal/Eye Discharge 02/11/2012 01/20/12 23.00 Yes
269 1000 mg/kg Ruffled Fur 01/30/2012 01/20/12 11.00 No