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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: alpha/beta Thujone mixture
CASRN: ="76231-76-0"
Study Number: C99037B
Exposure Route: GAVAGE
TDMS Number: 9903704
Sex: Female
Strain and Species: B6C3F1 Mice

Female Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Vehicle Control 10 61 61 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 61 62 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 62 69 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Alimentary System Liver 25 MG/KG 10 67 93 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Alimentary System Liver 25 MG/KG 10 67 94 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Alimentary System Liver 25 MG/KG 10 68 97 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Alimentary System Liver 50 MG/KG 10 69 101 65 1 Hematopoietic Cell Proliferation Minimal Natural Death
Alimentary System Liver 50 MG/KG 10 69 103 72 1 Hematopoietic Cell Proliferation Minimal Natural Death
Alimentary System Liver 50 MG/KG 10 70 106 83 1 Hematopoietic Cell Proliferation Minimal Natural Death
Alimentary System Liver 50 MG/KG 10 70 110 75 1 Hematopoietic Cell Proliferation Minimal Natural Death
Alimentary System Liver 75 MG/KG 10 72 118 51 1 Hematopoietic Cell Proliferation Minimal Natural Death
Alimentary System Liver 75 MG/KG 10 72 120 49 1 Hematopoietic Cell Proliferation Minimal Natural Death
Alimentary System Liver 75 MG/KG 10 72 119 42 1 Hepatodiaphragmatic Nodule Natural Death
Alimentary System Pancreas Acinus Vehicle Control 10 61 63 93 1 Atrophy Mild, Focal Terminal Sacrifice
Alimentary System Stomach Glandular Vehicle Control 10 61 62 93 1 Cyst Terminal Sacrifice
Alimentary System Stomach Glandular Vehicle Control 10 62 67 93 1 Cyst Terminal Sacrifice
Alimentary System Stomach Glandular Vehicle Control 10 62 67 93 1 Mineralization Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex 50 MG/KG 10 70 106 83 1 Accessory Adrenal Cortical Nodule Mild Natural Death
Genital System Uterus 12.5 MG/KG 10 65 84 93 1 Dilatation Minimal Terminal Sacrifice
Hematopoietic System Spleen Vehicle Control 10 62 66 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 25 MG/KG 10 68 100 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 6.25 MG/KG 1 63 71 93 1 Hyperplasia Minimal, Focal, Lymphoid Terminal Sacrifice
Nervous System Brain 50 MG/KG 10 69 104 93 1 Inflammation Minimal, Acute Terminal Sacrifice
Respiratory System Lung 50 MG/KG 10 69 103 72 1 Congestion Mild Natural Death
Respiratory System Lung 50 MG/KG 10 70 106 83 1 Congestion Minimal Natural Death
Respiratory System Lung 75 MG/KG 10 71 111 51 1 Congestion Mild Natural Death
Respiratory System Lung 75 MG/KG 10 71 112 49 1 Congestion Minimal Natural Death
Respiratory System Lung 75 MG/KG 10 72 116 56 1 Congestion Mild Natural Death
Respiratory System Lung 50 MG/KG 10 69 101 65 1 Hemorrhage Minimal Natural Death
Respiratory System Lung 50 MG/KG 10 69 105 75 1 Hemorrhage Minimal Natural Death
Respiratory System Lung 25 MG/KG 10 67 92 93 1 Infiltration Cellular Mild, Focal, Histiocyte Terminal Sacrifice
Respiratory System Lung 25 MG/KG 10 67 92 93 1 Inflammation Mild, Acute Terminal Sacrifice
Special Senses System Harderian Gland Vehicle Control 10 62 67 93 1 Inflammation Minimal, Acute Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 61 61 93 1 Casts Protein Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 61 63 93 1 Casts Protein Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 62 68 93 1 Casts Protein Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 61 65 93 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 50 MG/KG 10 70 106 83 1 Nephropathy Minimal Natural Death